SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zds'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_B_URFB999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 2zds PUTATIVE DNA-BINDING
PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ALA A 194
TYR A 186
ILE A 184
ILE A 135
 None
 0.91A 1upfB-2zdsA:
undetectable		 1upfB-2zdsA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)		 2zds PUTATIVE DNA-BINDING
PROTEIN
(Streptomyces
coelicolor) 		4 / 8 GLU A 178
ASP A 235
HIS A  72
GLU A  32
 None
 0.93A 1v7zA-2zdsA:
undetectable		 1v7zA-2zdsA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)		 2zds PUTATIVE DNA-BINDING
PROTEIN
(Streptomyces
coelicolor) 		4 / 8 GLU A 178
ASP A 235
HIS A  72
GLU A  32
 None
 0.95A 1v7zB-2zdsA:
undetectable		 1v7zB-2zdsA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_D_CRND5401_1
(CREATININE
AMIDOHYDROLASE)		 2zds PUTATIVE DNA-BINDING
PROTEIN
(Streptomyces
coelicolor) 		4 / 8 GLU A 178
ASP A 235
HIS A  72
GLU A  32
 None
 0.95A 1v7zD-2zdsA:
undetectable		 1v7zD-2zdsA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_E_CRNE6401_1
(CREATININE
AMIDOHYDROLASE)		 2zds PUTATIVE DNA-BINDING
PROTEIN
(Streptomyces
coelicolor) 		4 / 8 GLU A 178
ASP A 235
HIS A  72
GLU A  32
 None
 0.96A 1v7zE-2zdsA:
undetectable		 1v7zE-2zdsA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)		 2zds PUTATIVE DNA-BINDING
PROTEIN
(Streptomyces
coelicolor) 		4 / 8 GLU A 178
ASP A 235
HIS A  72
GLU A  32
 None
 0.95A 1v7zF-2zdsA:
undetectable		 1v7zF-2zdsA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 2zds PUTATIVE DNA-BINDING
PROTEIN
(Streptomyces
coelicolor) 		5 / 12 SER A 182
GLY A  75
PHE A 130
ALA A 108
ALA A  77
 None
 1.36A 2avdB-2zdsA:
undetectable		 2avdB-2zdsA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LBD_A_REAA500_1
(RETINOIC ACID
RECEPTOR GAMMA)		 2zds PUTATIVE DNA-BINDING
PROTEIN
(Streptomyces
coelicolor) 		5 / 12 LYS A  65
CYH A  66
LEU A  33
GLY A  37
LEU A  14
 None
 1.05A 2lbdA-2zdsA:
undetectable		 2lbdA-2zdsA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 2zds PUTATIVE DNA-BINDING
PROTEIN
(Streptomyces
coelicolor) 		3 / 3 SER A 292
HIS A 212
ASP A 264
 None
 0.65A 2wa2B-2zdsA:
undetectable		 2wa2B-2zdsA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)		 2zds PUTATIVE DNA-BINDING
PROTEIN
(Streptomyces
coelicolor) 		4 / 8 GLY A  75
ILE A 184
ALA A 108
HIS A  87
 None
 0.93A 2x0pA-2zdsA:
undetectable		 2x0pA-2zdsA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)		 2zds PUTATIVE DNA-BINDING
PROTEIN
(Streptomyces
coelicolor) 		4 / 8 GLU A 178
ASP A 235
HIS A  72
GLU A  32
 None
 0.92A 3a6jA-2zdsA:
undetectable		 3a6jA-2zdsA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 2zds PUTATIVE DNA-BINDING
PROTEIN
(Streptomyces
coelicolor) 		4 / 7 GLU A 178
ASP A 235
HIS A  72
GLU A  32
 None
 0.92A 3a6jB-2zdsA:
undetectable		 3a6jB-2zdsA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 2zds PUTATIVE DNA-BINDING
PROTEIN
(Streptomyces
coelicolor) 		4 / 8 GLU A 178
ASP A 235
HIS A  72
GLU A  32
 None
 0.93A 3a6jC-2zdsA:
undetectable		 3a6jC-2zdsA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 2zds PUTATIVE DNA-BINDING
PROTEIN
(Streptomyces
coelicolor) 		4 / 8 GLU A 178
ASP A 235
HIS A  72
GLU A  32
 None
 0.93A 3a6jE-2zdsA:
undetectable		 3a6jE-2zdsA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)		 2zds PUTATIVE DNA-BINDING
PROTEIN
(Streptomyces
coelicolor) 		4 / 8 GLU A 178
ASP A 235
HIS A  72
GLU A  32
 None
 0.93A 3a6jF-2zdsA:
undetectable		 3a6jF-2zdsA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_1
(MNMC2)		 2zds PUTATIVE DNA-BINDING
PROTEIN
(Streptomyces
coelicolor) 		4 / 6 GLY A 132
GLU A 183
ASP A 209
GLU A 294
 None
 1.06A 3vywC-2zdsA:
undetectable		 3vywC-2zdsA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 2zds PUTATIVE DNA-BINDING
PROTEIN
(Streptomyces
coelicolor) 		5 / 11 PHE A 204
GLY A 199
LEU A 165
ILE A  95
LEU A  91
 None
 1.13A 4kt0A-2zdsA:
undetectable
4kt0J-2zdsA:
undetectable		 4kt0A-2zdsA:
20.28
4kt0J-2zdsA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8W_G_MTXG301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 2zds PUTATIVE DNA-BINDING
PROTEIN
(Streptomyces
coelicolor) 		5 / 9 PHE A   4
GLY A  63
GLY A  30
LEU A  64
HIS A  56
 None
 1.42A 4l8wG-2zdsA:
0.5		 4l8wG-2zdsA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 2zds PUTATIVE DNA-BINDING
PROTEIN
(Streptomyces
coelicolor) 		4 / 4 HIS A 177
GLU A  32
HIS A 233
LEU A 282
 None
 1.35A 4m2rA-2zdsA:
undetectable		 4m2rA-2zdsA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 2zds PUTATIVE DNA-BINDING
PROTEIN
(Streptomyces
coelicolor) 		5 / 12 SER A  70
GLU A  32
ASP A 125
ALA A 116
ARG A 174
 None
 1.13A 4u95B-2zdsA:
undetectable		 4u95B-2zdsA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2zds PUTATIVE DNA-BINDING
PROTEIN
(Streptomyces
coelicolor) 		5 / 11 LEU A  33
GLU A  41
LEU A  16
LEU A  58
LEU A  59
 None
 1.12A 4wg0K-2zdsA:
undetectable
4wg0L-2zdsA:
undetectable
4wg0M-2zdsA:
undetectable		 4wg0K-2zdsA:
12.20
4wg0L-2zdsA:
12.20
4wg0M-2zdsA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 2zds PUTATIVE DNA-BINDING
PROTEIN
(Streptomyces
coelicolor) 		4 / 6 GLY A 132
ASP A  80
GLY A  75
ARG A 160
 None
 1.03A 4z53A-2zdsA:
undetectable
4z53B-2zdsA:
undetectable		 4z53A-2zdsA:
18.95
4z53B-2zdsA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UH6_C_RFPC1201_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 2zds PUTATIVE DNA-BINDING
PROTEIN
(Streptomyces
coelicolor) 		5 / 12 ASP A 125
SER A  70
ASN A 207
ILE A 128
ARG A 174
 None
 1.40A 5uh6C-2zdsA:
undetectable		 5uh6C-2zdsA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHG_C_RFPC1201_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 2zds PUTATIVE DNA-BINDING
PROTEIN
(Streptomyces
coelicolor) 		5 / 12 ASP A 125
SER A  70
ASN A 207
ILE A 128
ARG A 174
 None
 1.32A 5uhgC-2zdsA:
undetectable		 5uhgC-2zdsA:
14.94