SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ze0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		3 / 3 TRP A 317
VAL A  10
TRP A   6
 None
 1.25A 1c4dA-2ze0A:
undetectable
1c4dB-2ze0A:
undetectable		 1c4dA-2ze0A:
3.99
1c4dB-2ze0A:
3.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		5 / 11 ILE A  27
GLY A 427
GLY A  24
PHE A 424
ASP A  21
 CA  A 552 (-4.7A)
None
None
None
CA  A 552 (-3.1A)
 1.03A 1ho5A-2ze0A:
undetectable		 1ho5A-2ze0A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_A_DVAA8_0
(MINI-GRAMICIDIN A)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		4 / 5 VAL A  10
TRP A   6
ALA A  11
TRP A   5
 None
 1.37A 1kqeA-2ze0A:
undetectable
1kqeE-2ze0A:
undetectable		 1kqeA-2ze0A:
2.87
1kqeE-2ze0A:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_B_DVAB8_0
(MINI-GRAMICIDIN A)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		4 / 4 VAL A  10
TRP A   6
ALA A  11
TRP A   5
 None
 1.40A 1kqeB-2ze0A:
undetectable
1kqeD-2ze0A:
undetectable		 1kqeB-2ze0A:
2.87
1kqeD-2ze0A:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_D_DVAD8_0
(MINI-GRAMICIDIN A)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		4 / 4 ALA A  11
TRP A   5
VAL A  10
TRP A   6
 None
 1.40A 1kqeB-2ze0A:
undetectable
1kqeD-2ze0A:
undetectable		 1kqeB-2ze0A:
2.87
1kqeD-2ze0A:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRL_B_DOLB301_1
(STREPTOGRAMIN A
ACETYLTRANSFERASE)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		5 / 12 ILE A  47
HIS A 325
VAL A 100
TYR A  63
ASP A 199
 None
 1.48A 1mrlB-2ze0A:
undetectable
1mrlC-2ze0A:
undetectable		 1mrlB-2ze0A:
17.27
1mrlC-2ze0A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		4 / 8 ILE A 193
LEU A  97
PHE A 196
MET A 184
 None
 0.76A 1v55N-2ze0A:
undetectable
1v55W-2ze0A:
undetectable		 1v55N-2ze0A:
19.59
1v55W-2ze0A:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		4 / 8 ILE A 193
LEU A  97
PHE A 196
MET A 184
 None
 0.77A 2eijN-2ze0A:
undetectable
2eijW-2ze0A:
undetectable		 2eijN-2ze0A:
19.59
2eijW-2ze0A:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		4 / 8 ILE A 193
LEU A  97
PHE A 196
MET A 184
 None
 0.77A 2eikN-2ze0A:
undetectable
2eikW-2ze0A:
undetectable		 2eikN-2ze0A:
19.59
2eikW-2ze0A:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		4 / 8 ILE A 193
LEU A  97
PHE A 196
MET A 184
 None
 0.77A 2eilN-2ze0A:
undetectable
2eilW-2ze0A:
undetectable		 2eilN-2ze0A:
19.59
2eilW-2ze0A:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		4 / 8 ILE A 193
LEU A  97
PHE A 196
MET A 184
 None
 0.82A 2einA-2ze0A:
undetectable
2einJ-2ze0A:
undetectable		 2einA-2ze0A:
19.59
2einJ-2ze0A:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA6_A_SCKA902_1
(ACETYLCHOLINESTERASE)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		5 / 10 ASN A 324
GLU A 366
LEU A  43
LEU A  40
TYR A  39
 None
 1.40A 2ha6A-2ze0A:
undetectable		 2ha6A-2ze0A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		3 / 3 ASP A 376
THR A 412
PRO A 413
 None
 0.67A 2pynB-2ze0A:
undetectable		 2pynB-2ze0A:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_4
(PROTEASE RETROPEPSIN)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		3 / 3 ASP A 376
THR A 412
PRO A 413
 None
 0.66A 2q64B-2ze0A:
undetectable		 2q64B-2ze0A:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		3 / 3 ASP A 376
THR A 412
PRO A 413
 None
 0.69A 2qakB-2ze0A:
undetectable		 2qakB-2ze0A:
10.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		4 / 6 LEU A  40
TRP A 453
ILE A 367
ARG A 446
 None
 0.90A 2rlfB-2ze0A:
undetectable
2rlfC-2ze0A:
undetectable		 2rlfB-2ze0A:
6.44
2rlfC-2ze0A:
6.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		4 / 8 ILE A 193
LEU A  97
PHE A 196
MET A 184
 None
 0.79A 3abkA-2ze0A:
undetectable
3abkJ-2ze0A:
undetectable		 3abkA-2ze0A:
19.59
3abkJ-2ze0A:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		4 / 8 ILE A 193
LEU A  97
PHE A 196
MET A 184
 None
 0.76A 3ablN-2ze0A:
undetectable
3ablW-2ze0A:
undetectable		 3ablN-2ze0A:
19.59
3ablW-2ze0A:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		4 / 8 ILE A 193
LEU A  97
PHE A 196
MET A 184
 None
 0.74A 3abmN-2ze0A:
undetectable
3abmW-2ze0A:
undetectable		 3abmN-2ze0A:
19.59
3abmW-2ze0A:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		4 / 7 ILE A 193
LEU A  97
PHE A 196
MET A 184
 None
 0.77A 3ag2N-2ze0A:
undetectable
3ag2W-2ze0A:
undetectable		 3ag2N-2ze0A:
19.59
3ag2W-2ze0A:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		4 / 7 ILE A 193
LEU A  97
PHE A 196
MET A 184
 None
 0.72A 3ag4N-2ze0A:
undetectable
3ag4W-2ze0A:
undetectable		 3ag4N-2ze0A:
19.59
3ag4W-2ze0A:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		4 / 8 ILE A 193
LEU A  97
PHE A 196
MET A 184
 None
 0.77A 3asoN-2ze0A:
undetectable
3asoW-2ze0A:
undetectable		 3asoN-2ze0A:
19.59
3asoW-2ze0A:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		4 / 8 ASP A  25
PHE A  75
ASP A  21
GLY A  26
 CA  A 552 (-2.7A)
None
CA  A 552 (-3.1A)
None
 0.90A 3c0zB-2ze0A:
undetectable		 3c0zB-2ze0A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_2
(PROTEASE)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		5 / 9 ASP A  80
ILE A  33
GLY A  28
ILE A  27
ILE A  53
 None
None
CA  A 552 ( 4.7A)
CA  A 552 (-4.7A)
None
 1.11A 3ekyB-2ze0A:
undetectable		 3ekyB-2ze0A:
10.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAM_A_LLLA500_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		5 / 12 ASP A 382
ASP A 408
ASP A  60
ASP A  64
TYR A  15
 None
 1.49A 3hamA-2ze0A:
1.5		 3hamA-2ze0A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_B_MTXB164_1
(DIHYDROFOLATE
REDUCTASE)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		5 / 12 ILE A  96
ALA A  11
LEU A  93
ILE A  33
LEU A  84
 None
 1.17A 3ia4B-2ze0A:
undetectable		 3ia4B-2ze0A:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_1
(DIHYDROFOLATE
REDUCTASE)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		5 / 12 ILE A  96
ALA A  11
LEU A  93
ILE A  33
LEU A  84
 None
 1.13A 3ia4D-2ze0A:
undetectable		 3ia4D-2ze0A:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_1
(PROTEASE)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		5 / 12 ASP A  80
ILE A  33
GLY A  28
ILE A  27
ILE A  53
 None
None
CA  A 552 ( 4.7A)
CA  A 552 (-4.7A)
None
 1.07A 3ndxA-2ze0A:
undetectable		 3ndxA-2ze0A:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_1
(HIV-1 PROTEASE)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		4 / 7 GLY A 349
ALA A 350
VAL A 546
ILE A 460
 None
 0.78A 3t3cA-2ze0A:
undetectable		 3t3cA-2ze0A:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_3
(PROTEASE)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		3 / 3 ASP A 376
THR A 412
PRO A 413
 None
 0.63A 3tkgD-2ze0A:
undetectable		 3tkgD-2ze0A:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5V_C_ACTC510_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		4 / 5 THR A 473
ASP A 475
LYS A 310
GLU A 313
 None
 1.38A 3v5vC-2ze0A:
undetectable
3v5vD-2ze0A:
0.2		 3v5vC-2ze0A:
21.35
3v5vD-2ze0A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_B_ACTB502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		4 / 5 LYS A 310
GLU A 313
THR A 473
ASP A 475
 None
 1.38A 4e7cA-2ze0A:
undetectable
4e7cB-2ze0A:
undetectable		 4e7cA-2ze0A:
21.35
4e7cB-2ze0A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		4 / 5 GLY A 259
MET A 229
ASN A 230
GLU A 283
 None
 1.26A 4fglC-2ze0A:
undetectable		 4fglC-2ze0A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_A_SASA806_1
(SEPIAPTERIN
REDUCTASE)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		5 / 12 LEU A  97
PHE A  81
PRO A  16
ASP A  79
GLY A  76
 None
 1.49A 4j7xA-2ze0A:
undetectable		 4j7xA-2ze0A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		5 / 12 LEU A 348
GLY A 349
MET A 459
ILE A 460
VAL A  10
 None
 1.27A 4okwA-2ze0A:
undetectable		 4okwA-2ze0A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_1
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		3 / 3 SER A 330
GLU A 445
GLU A  42
 None
 0.88A 4ymgB-2ze0A:
undetectable		 4ymgB-2ze0A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		4 / 7 GLY A 195
ASP A 250
HIS A  89
ASP A 194
 None
 1.08A 5nnwD-2ze0A:
undetectable		 5nnwD-2ze0A:
8.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		4 / 7 GLY A 195
ASP A 250
HIS A  89
ASP A 194
 None
 1.07A 5no9D-2ze0A:
undetectable		 5no9D-2ze0A:
8.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_0
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		5 / 12 LEU A  40
GLN A  13
TRP A  49
VAL A  48
LEU A  93
 None
 1.24A 5ubbA-2ze0A:
undetectable		 5ubbA-2ze0A:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		4 / 8 ILE A 193
LEU A  97
PHE A 196
MET A 184
 None
 0.78A 5zcpN-2ze0A:
undetectable
5zcpW-2ze0A:
undetectable		 5zcpN-2ze0A:
19.59
5zcpW-2ze0A:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		4 / 8 ILE A 193
LEU A  97
PHE A 196
MET A 184
 None
 0.79A 5zcqN-2ze0A:
undetectable
5zcqW-2ze0A:
undetectable		 5zcqN-2ze0A:
19.59
5zcqW-2ze0A:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		4 / 8 TRP A   6
TYR A 471
GLU A   8
TRP A 317
 None
 1.09A 6c71B-2ze0A:
undetectable		 6c71B-2ze0A:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)		 2ze0 ALPHA-GLUCOSIDASE
(Geobacillus
sp.
HTA-462) 		3 / 3 GLU A 467
LEU A 468
ARG A 489
 None
 0.83A 6d8fA-2ze0A:
undetectable		 6d8fA-2ze0A:
22.00