SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zf3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_H_LFXH0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 2zf3 HYPOTHETICAL PROTEIN
VIOE
(Chromobacterium
violaceum) 		4 / 6 SER A 154
ARG A 126
GLY A 135
GLU A 165
 None
 1.16A 3k9fA-2zf3A:
undetectable
3k9fB-2zf3A:
undetectable
3k9fD-2zf3A:
undetectable		 3k9fA-2zf3A:
18.90
3k9fB-2zf3A:
18.90
3k9fD-2zf3A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 2zf3 HYPOTHETICAL PROTEIN
VIOE
(Chromobacterium
violaceum) 		4 / 5 CYH A  35
SER A  15
LEU A 158
LEU A 110
 None
 1.23A 4n09D-2zf3A:
undetectable		 4n09D-2zf3A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_I_BEZI1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 2zf3 HYPOTHETICAL PROTEIN
VIOE
(Chromobacterium
violaceum) 		3 / 3 SER A  15
TYR A  17
TYR A  34
 None
 0.73A 5lakA-2zf3A:
undetectable
5lakI-2zf3A:
undetectable		 5lakA-2zf3A:
22.15
5lakI-2zf3A:
4.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 2zf3 HYPOTHETICAL PROTEIN
VIOE
(Chromobacterium
violaceum) 		3 / 3 SER A  15
TYR A  17
TYR A  34
 None
 0.73A 5lakC-2zf3A:
undetectable
5lakJ-2zf3A:
undetectable		 5lakC-2zf3A:
22.15
5lakJ-2zf3A:
4.94