SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zf9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		 2zf9 SCAE CELL-SURFACE
ANCHORED SCAFFOLDIN
PROTEIN
(Ruminococcus
flavefaciens) 		4 / 7 TYR A  56
ASP A 115
GLU A  50
PHE A 151
 None
 1.16A 1b2iA-2zf9A:
undetectable		 1b2iA-2zf9A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2zf9 SCAE CELL-SURFACE
ANCHORED SCAFFOLDIN
PROTEIN
(Ruminococcus
flavefaciens) 		4 / 7 LYS A  70
LEU A 123
GLN A 124
PHE A 102
 None
 1.03A 2dysC-2zf9A:
undetectable
2dysJ-2zf9A:
undetectable		 2dysC-2zf9A:
20.74
2dysJ-2zf9A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O5Y_H_STRH249_1
(CHIMERIC ANTIBODY
FAB 1E9-DB3)		 2zf9 SCAE CELL-SURFACE
ANCHORED SCAFFOLDIN
PROTEIN
(Ruminococcus
flavefaciens) 		4 / 7 GLY A  51
THR A  25
TRP A 166
SER A  20
 None
 1.10A 2o5yH-2zf9A:
2.6
2o5yL-2zf9A:
2.8		 2o5yH-2zf9A:
23.33
2o5yL-2zf9A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2zf9 SCAE CELL-SURFACE
ANCHORED SCAFFOLDIN
PROTEIN
(Ruminococcus
flavefaciens) 		4 / 7 LYS A  70
LEU A 123
GLN A 124
PHE A 102
 None
 0.91A 2zxwC-2zf9A:
undetectable
2zxwJ-2zf9A:
undetectable		 2zxwC-2zf9A:
20.74
2zxwJ-2zf9A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2zf9 SCAE CELL-SURFACE
ANCHORED SCAFFOLDIN
PROTEIN
(Ruminococcus
flavefaciens) 		4 / 8 LYS A  70
LEU A 123
GLN A 124
PHE A 102
 None
 0.96A 3asoC-2zf9A:
undetectable
3asoJ-2zf9A:
undetectable		 3asoC-2zf9A:
20.74
3asoJ-2zf9A:
17.07