SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zg6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)
2zg6 PUTATIVE
UNCHARACTERIZED
PROTEIN ST2620

(Sulfurisphaera
tokodaii)
4 / 7 LEU A  14
THR A  13
GLY A  16
LEU A  96
None
0.92A 1gtiB-2zg6A:
undetectable
1gtiB-2zg6A:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)
2zg6 PUTATIVE
UNCHARACTERIZED
PROTEIN ST2620

(Sulfurisphaera
tokodaii)
5 / 12 LEU A 128
LEU A 114
ALA A 115
LEU A   7
VAL A 170
None
1.30A 1s9pB-2zg6A:
undetectable
1s9pB-2zg6A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)
2zg6 PUTATIVE
UNCHARACTERIZED
PROTEIN ST2620

(Sulfurisphaera
tokodaii)
4 / 4 ASP A  99
LEU A 104
LEU A 101
LEU A 207
None
1.42A 1u18A-2zg6A:
undetectable
1u18A-2zg6A:
26.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)
2zg6 PUTATIVE
UNCHARACTERIZED
PROTEIN ST2620

(Sulfurisphaera
tokodaii)
5 / 12 GLY A  11
SER A 118
ASP A 172
ARG A  43
ALA A  46
None
1.16A 2br4D-2zg6A:
2.7
2br4D-2zg6A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
2zg6 PUTATIVE
UNCHARACTERIZED
PROTEIN ST2620

(Sulfurisphaera
tokodaii)
3 / 3 PRO A 188
ASP A 177
GLU A 175
None
0.86A 3v4tC-2zg6A:
undetectable
3v4tC-2zg6A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)
2zg6 PUTATIVE
UNCHARACTERIZED
PROTEIN ST2620

(Sulfurisphaera
tokodaii)
4 / 8 LEU A  14
ARG A 193
VAL A 204
GLY A 171
None
0.92A 4eq4B-2zg6A:
undetectable
4eq4B-2zg6A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
2zg6 PUTATIVE
UNCHARACTERIZED
PROTEIN ST2620

(Sulfurisphaera
tokodaii)
4 / 7 GLU A  86
LYS A  85
LEU A  84
LEU A  69
None
0.67A 4wg0B-2zg6A:
undetectable
4wg0C-2zg6A:
undetectable
4wg0B-2zg6A:
5.58
4wg0C-2zg6A:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
2zg6 PUTATIVE
UNCHARACTERIZED
PROTEIN ST2620

(Sulfurisphaera
tokodaii)
4 / 7 LEU A  69
GLU A  86
LYS A  85
LEU A  84
None
0.75A 4wg0L-2zg6A:
undetectable
4wg0M-2zg6A:
undetectable
4wg0L-2zg6A:
5.58
4wg0M-2zg6A:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_B_ADNB902_1
(MYOSIN HEAVY CHAIN
KINASE A)
2zg6 PUTATIVE
UNCHARACTERIZED
PROTEIN ST2620

(Sulfurisphaera
tokodaii)
5 / 10 PHE A  17
ALA A  46
VAL A  15
LEU A 116
LEU A 127
None
1.30A 4zmeB-2zg6A:
undetectable
4zmeB-2zg6A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA609_0
(ALPHA-AMYLASE)
2zg6 PUTATIVE
UNCHARACTERIZED
PROTEIN ST2620

(Sulfurisphaera
tokodaii)
4 / 7 LYS A  47
GLY A  11
ASP A  99
TYR A  97
None
1.30A 6ag0A-2zg6A:
undetectable
6ag0A-2zg6A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC609_0
(ALPHA-AMYLASE)
2zg6 PUTATIVE
UNCHARACTERIZED
PROTEIN ST2620

(Sulfurisphaera
tokodaii)
4 / 7 LYS A  47
GLY A  11
ASP A  99
TYR A  97
None
1.36A 6ag0C-2zg6A:
undetectable
6ag0C-2zg6A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
2zg6 PUTATIVE
UNCHARACTERIZED
PROTEIN ST2620

(Sulfurisphaera
tokodaii)
4 / 7 ASP A  31
ARG A  79
GLN A  27
LYS A  24
None
1.49A 6g31A-2zg6A:
undetectable
6g31A-2zg6A:
19.19