SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zgd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3O02_B_JN3B1_1 (CELL INVASION PROTEIN SIPD)	2zgd	3 REPEAT SYNTHETIC ANKYRIN (-)	5 / 10	ILE A 108 ASN A 67 ALA A 65 LEU A 77 LEU A 61	None	1.18A	3o02A-2zgdA: undetectable 3o02B-2zgdA: undetectable	3o02A-2zgdA: 16.94 3o02B-2zgdA: 16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ND7_B_TA1B601_1 (TUBULIN BETA-2B CHAIN)	2zgd	3 REPEAT SYNTHETIC ANKYRIN (-)	5 / 12	VAL A 40 ASP A 38 GLU A 39 LEU A 105 ALA A 32	None CD A 413 ( 2.4A) CD A 410 ( 2.1A) None None	1.09A	5nd7B-2zgdA: undetectable	5nd7B-2zgdA: 14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_B_TA1B501_1 (TUBULIN BETA CHAIN)	2zgd	3 REPEAT SYNTHETIC ANKYRIN (-)	5 / 12	VAL A 40 ASP A 38 GLU A 39 LEU A 105 ALA A 32	None CD A 413 ( 2.4A) CD A 410 ( 2.1A) None None	1.09A	6ew0B-2zgdA: undetectable	6ew0B-2zgdA: 20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_D_TA1D501_1 (TUBULIN BETA CHAIN)	2zgd	3 REPEAT SYNTHETIC ANKYRIN (-)	5 / 12	VAL A 40 ASP A 38 GLU A 39 LEU A 105 ALA A 32	None CD A 413 ( 2.4A) CD A 410 ( 2.1A) None None	1.09A	6ew0D-2zgdA: undetectable	6ew0D-2zgdA: 20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_F_TA1F502_1 (TUBULIN BETA CHAIN)	2zgd	3 REPEAT SYNTHETIC ANKYRIN (-)	5 / 12	VAL A 40 ASP A 38 GLU A 39 LEU A 105 ALA A 32	None CD A 413 ( 2.4A) CD A 410 ( 2.1A) None None	1.09A	6ew0F-2zgdA: undetectable	6ew0F-2zgdA: 20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_G_TA1G501_1 (TUBULIN BETA CHAIN)	2zgd	3 REPEAT SYNTHETIC ANKYRIN (-)	5 / 12	VAL A 40 ASP A 38 GLU A 39 LEU A 105 ALA A 32	None CD A 413 ( 2.4A) CD A 410 ( 2.1A) None None	1.08A	6ew0G-2zgdA: undetectable	6ew0G-2zgdA: 20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_H_TA1H501_1 (TUBULIN BETA CHAIN)	2zgd	3 REPEAT SYNTHETIC ANKYRIN (-)	5 / 12	VAL A 40 ASP A 38 GLU A 39 LEU A 105 ALA A 32	None CD A 413 ( 2.4A) CD A 410 ( 2.1A) None None	1.09A	6ew0H-2zgdA: undetectable	6ew0H-2zgdA: 20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_I_TA1I501_1 (TUBULIN BETA CHAIN)	2zgd	3 REPEAT SYNTHETIC ANKYRIN (-)	5 / 12	VAL A 40 ASP A 38 GLU A 39 LEU A 105 ALA A 32	None CD A 413 ( 2.4A) CD A 410 ( 2.1A) None None	1.09A	6ew0I-2zgdA: undetectable	6ew0I-2zgdA: 20.18

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3O02_B_JN3B1_1","CELL INVASION PROTEIN SIPD;CELL INVASION PROTEIN SIPD","2zgd","3 REPEAT SYNTHETIC ANKYRIN","-",5,"ILE A 108;ASN A  67;ALA A  65;LEU A  77;LEU A  61","None","1.18A","3o02A-2zgdA:undetectable;3o02B-2zgdA:undetectable","3o02A-2zgdA:16.94;3o02B-2zgdA:16.94"],["5ND7_B_TA1B601_1","TUBULIN BETA-2B CHAIN","2zgd","3 REPEAT SYNTHETIC ANKYRIN","-",5,"VAL A  40;ASP A  38;GLU A  39;LEU A 105;ALA A  32","None; CD A 413 ( 2.4A); CD A 410 ( 2.1A);None;None","1.09A","5nd7B-2zgdA:undetectable","5nd7B-2zgdA:14.38"],["6EW0_B_TA1B501_1","TUBULIN BETA CHAIN","2zgd","3 REPEAT SYNTHETIC ANKYRIN","-",5,"VAL A  40;ASP A  38;GLU A  39;LEU A 105;ALA A  32","None; CD A 413 ( 2.4A); CD A 410 ( 2.1A);None;None","1.09A","6ew0B-2zgdA:undetectable","6ew0B-2zgdA:20.18"],["6EW0_D_TA1D501_1","TUBULIN BETA CHAIN","2zgd","3 REPEAT SYNTHETIC ANKYRIN","-",5,"VAL A  40;ASP A  38;GLU A  39;LEU A 105;ALA A  32","None; CD A 413 ( 2.4A); CD A 410 ( 2.1A);None;None","1.09A","6ew0D-2zgdA:undetectable","6ew0D-2zgdA:20.18"],["6EW0_F_TA1F502_1","TUBULIN BETA CHAIN","2zgd","3 REPEAT SYNTHETIC ANKYRIN","-",5,"VAL A  40;ASP A  38;GLU A  39;LEU A 105;ALA A  32","None; CD A 413 ( 2.4A); CD A 410 ( 2.1A);None;None","1.09A","6ew0F-2zgdA:undetectable","6ew0F-2zgdA:20.18"],["6EW0_G_TA1G501_1","TUBULIN BETA CHAIN","2zgd","3 REPEAT SYNTHETIC ANKYRIN","-",5,"VAL A  40;ASP A  38;GLU A  39;LEU A 105;ALA A  32","None; CD A 413 ( 2.4A); CD A 410 ( 2.1A);None;None","1.08A","6ew0G-2zgdA:undetectable","6ew0G-2zgdA:20.18"],["6EW0_H_TA1H501_1","TUBULIN BETA CHAIN","2zgd","3 REPEAT SYNTHETIC ANKYRIN","-",5,"VAL A  40;ASP A  38;GLU A  39;LEU A 105;ALA A  32","None; CD A 413 ( 2.4A); CD A 410 ( 2.1A);None;None","1.09A","6ew0H-2zgdA:undetectable","6ew0H-2zgdA:20.18"],["6EW0_I_TA1I501_1","TUBULIN BETA CHAIN","2zgd","3 REPEAT SYNTHETIC ANKYRIN","-",5,"VAL A  40;ASP A  38;GLU A  39;LEU A 105;ALA A  32","None; CD A 413 ( 2.4A); CD A 410 ( 2.1A);None;None","1.09A","6ew0I-2zgdA:undetectable","6ew0I-2zgdA:20.18"]]