SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zhh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 2zhh REDOX-SENSITIVE
TRANSCRIPTIONAL
ACTIVATOR SOXR
(Escherichia
coli) 		4 / 8 VAL A  57
THR A  38
TYR A  31
LEU A  28
 None
 0.87A 1z2bB-2zhhA:
undetectable		 1z2bB-2zhhA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 2zhh REDOX-SENSITIVE
TRANSCRIPTIONAL
ACTIVATOR SOXR
(Escherichia
coli) 		5 / 12 GLU A  32
LEU A  86
ASP A  52
SER A  39
ILE A  37
 None
 1.49A 4djeA-2zhhA:
undetectable		 4djeA-2zhhA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 2zhh REDOX-SENSITIVE
TRANSCRIPTIONAL
ACTIVATOR SOXR
(Escherichia
coli) 		3 / 3 TYR A  49
ARG A  47
SER A  39
 None
 0.76A 4khpI-2zhhA:
undetectable
4khpJ-2zhhA:
undetectable		 4khpI-2zhhA:
22.93
4khpJ-2zhhA:
25.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 2zhh REDOX-SENSITIVE
TRANSCRIPTIONAL
ACTIVATOR SOXR
(Escherichia
coli) 		3 / 3 TYR A  49
ARG A  47
SER A  39
 None
 1.19A 4lf7I-2zhhA:
undetectable
4lf7J-2zhhA:
undetectable		 4lf7I-2zhhA:
20.73
4lf7J-2zhhA:
27.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 2zhh REDOX-SENSITIVE
TRANSCRIPTIONAL
ACTIVATOR SOXR
(Escherichia
coli) 		3 / 3 TYR A  49
ARG A  47
SER A  39
 None
 1.19A 4lf8I-2zhhA:
undetectable
4lf8J-2zhhA:
undetectable		 4lf8I-2zhhA:
20.73
4lf8J-2zhhA:
27.45