SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zhy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_A_EAAA224_1
(GLUTATHIONE
TRANSFERASE)		 2zhy ATP:COB(I)ALAMIN
ADENOSYLTRANSFERASE,
PUTATIVE
(Burkholderia
thailandensis) 		5 / 12 GLY A 117
LEU A  49
LEU A  62
VAL A  58
ALA A 169
 None
 1.10A 1gseA-2zhyA:
undetectable		 1gseA-2zhyA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_B_EAAB224_1
(GLUTATHIONE
TRANSFERASE)		 2zhy ATP:COB(I)ALAMIN
ADENOSYLTRANSFERASE,
PUTATIVE
(Burkholderia
thailandensis) 		5 / 12 GLY A 117
LEU A  49
LEU A  62
VAL A  58
ALA A 169
 None
 1.04A 1gseB-2zhyA:
undetectable		 1gseB-2zhyA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 2zhy ATP:COB(I)ALAMIN
ADENOSYLTRANSFERASE,
PUTATIVE
(Burkholderia
thailandensis) 		4 / 8 ARG A 150
ILE A  84
LEU A  76
GLY A  73
 None
 0.87A 2tsrB-2zhyA:
undetectable		 2tsrB-2zhyA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2zhy ATP:COB(I)ALAMIN
ADENOSYLTRANSFERASE,
PUTATIVE
(Burkholderia
thailandensis) 		4 / 7 PRO A  55
ALA A 169
LEU A 166
ALA A 115
 None
 0.84A 2vcvA-2zhyA:
undetectable		 2vcvA-2zhyA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2zhy ATP:COB(I)ALAMIN
ADENOSYLTRANSFERASE,
PUTATIVE
(Burkholderia
thailandensis) 		5 / 9 PRO A  55
LEU A  54
ALA A 169
LEU A 166
ALA A 115
 None
 1.16A 2vcvD-2zhyA:
undetectable		 2vcvD-2zhyA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2zhy ATP:COB(I)ALAMIN
ADENOSYLTRANSFERASE,
PUTATIVE
(Burkholderia
thailandensis) 		4 / 7 PRO A  55
ALA A 169
LEU A 166
ALA A 115
 None
 0.83A 2vcvG-2zhyA:
undetectable		 2vcvG-2zhyA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2zhy ATP:COB(I)ALAMIN
ADENOSYLTRANSFERASE,
PUTATIVE
(Burkholderia
thailandensis) 		4 / 6 PRO A  55
ALA A 169
LEU A 166
ALA A 115
 None
 0.87A 2vcvK-2zhyA:
undetectable		 2vcvK-2zhyA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2zhy ATP:COB(I)ALAMIN
ADENOSYLTRANSFERASE,
PUTATIVE
(Burkholderia
thailandensis) 		4 / 7 PRO A  55
ALA A 169
LEU A 166
ALA A 115
 None
 1.08A 2vcvL-2zhyA:
undetectable		 2vcvL-2zhyA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 2zhy ATP:COB(I)ALAMIN
ADENOSYLTRANSFERASE,
PUTATIVE
(Burkholderia
thailandensis) 		4 / 6 LEU A 138
ILE A 135
LEU A  76
GLU A  75
 None
 0.94A 4w5nA-2zhyA:
undetectable		 4w5nA-2zhyA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2zhy ATP:COB(I)ALAMIN
ADENOSYLTRANSFERASE,
PUTATIVE
(Burkholderia
thailandensis) 		5 / 12 CYH A 124
ILE A  65
LEU A  54
LEU A 166
LEU A 162
 None
 1.18A 4xumA-2zhyA:
undetectable		 4xumA-2zhyA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_I_DIFI1006_1
(SERUM ALBUMIN)		 2zhy ATP:COB(I)ALAMIN
ADENOSYLTRANSFERASE,
PUTATIVE
(Burkholderia
thailandensis) 		5 / 10 ARG A 116
ARG A  59
LEU A  62
ILE A  46
ALA A  51
 None
 1.44A 4z69I-2zhyA:
3.6		 4z69I-2zhyA:
14.51