SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ziu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_2
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN)
IGG2B-KAPPA 40-50
FAB (LIGHT CHAIN))		 2ziu CROSSOVER JUNCTION
ENDONUCLEASE EME1
MUS81 PROTEIN
(Danio
rerio;
Homo
sapiens) 		4 / 7 THR A 560
SER A 559
TYR B 514
LEU B 510
 None
 1.06A 1ibgL-2ziuA:
undetectable		 1ibgL-2ziuA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_A_DVAA6_0
(MINI-GRAMICIDIN A)		 2ziu CROSSOVER JUNCTION
ENDONUCLEASE EME1
(Homo
sapiens) 		3 / 3 ALA B 318
VAL B 364
TRP B 429
 None
 0.81A 1kqeA-2ziuB:
undetectable
1kqeE-2ziuB:
undetectable		 1kqeA-2ziuB:
2.46
1kqeE-2ziuB:
2.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_B_DVAB6_0
(MINI-GRAMICIDIN A)		 2ziu CROSSOVER JUNCTION
ENDONUCLEASE EME1
(Homo
sapiens) 		3 / 3 ALA B 318
VAL B 364
TRP B 429
 None
 0.82A 1kqeB-2ziuB:
undetectable
1kqeD-2ziuB:
undetectable		 1kqeB-2ziuB:
2.46
1kqeD-2ziuB:
2.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_D_DVAD6_0
(MINI-GRAMICIDIN A)		 2ziu CROSSOVER JUNCTION
ENDONUCLEASE EME1
(Homo
sapiens) 		3 / 3 TRP B 429
ALA B 318
VAL B 364
 None
 0.82A 1kqeB-2ziuB:
undetectable
1kqeD-2ziuB:
undetectable		 1kqeB-2ziuB:
2.46
1kqeD-2ziuB:
2.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_E_DVAE6_0
(MINI-GRAMICIDIN A)		 2ziu CROSSOVER JUNCTION
ENDONUCLEASE EME1
(Homo
sapiens) 		3 / 3 TRP B 429
ALA B 318
VAL B 364
 None
 0.83A 1kqeA-2ziuB:
undetectable
1kqeE-2ziuB:
undetectable		 1kqeA-2ziuB:
2.46
1kqeE-2ziuB:
2.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 2ziu CROSSOVER JUNCTION
ENDONUCLEASE EME1
(Homo
sapiens) 		3 / 3 ALA B 318
VAL B 364
TRP B 429
 None
 0.81A 1micA-2ziuB:
undetectable
1micB-2ziuB:
undetectable		 1micA-2ziuB:
3.47
1micB-2ziuB:
3.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 6 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.70A 1v54A-2ziuA:
undetectable
1v54J-2ziuA:
undetectable		 1v54A-2ziuA:
18.55
1v54J-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 7 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.73A 1v54N-2ziuA:
undetectable
1v54W-2ziuA:
undetectable		 1v54N-2ziuA:
18.55
1v54W-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 7 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.75A 1v55A-2ziuA:
undetectable
1v55J-2ziuA:
undetectable		 1v55A-2ziuA:
18.55
1v55J-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 8 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.79A 1v55N-2ziuA:
undetectable
1v55W-2ziuA:
undetectable		 1v55N-2ziuA:
18.55
1v55W-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 6 LEU A 581
LEU A 593
LEU A 540
LEU A 604
 None
 0.86A 2ab2A-2ziuA:
undetectable		 2ab2A-2ziuA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 6 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.71A 2dyrA-2ziuA:
undetectable
2dyrJ-2ziuA:
undetectable		 2dyrA-2ziuA:
18.55
2dyrJ-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 7 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.76A 2dyrN-2ziuA:
undetectable
2dyrW-2ziuA:
undetectable		 2dyrN-2ziuA:
18.55
2dyrW-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 6 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.71A 2dysA-2ziuA:
undetectable
2dysJ-2ziuA:
undetectable		 2dysA-2ziuA:
18.55
2dysJ-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 6 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.70A 2dysN-2ziuA:
undetectable
2dysW-2ziuA:
undetectable		 2dysN-2ziuA:
18.55
2dysW-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 6 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.79A 2eijA-2ziuA:
undetectable
2eijJ-2ziuA:
undetectable		 2eijA-2ziuA:
18.55
2eijJ-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 7 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.76A 2eikA-2ziuA:
undetectable
2eikJ-2ziuA:
undetectable		 2eikA-2ziuA:
18.55
2eikJ-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 6 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.74A 2eilA-2ziuA:
undetectable
2eilJ-2ziuA:
undetectable		 2eilA-2ziuA:
18.55
2eilJ-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 8 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.71A 2eilN-2ziuA:
undetectable
2eilW-2ziuA:
undetectable		 2eilN-2ziuA:
18.55
2eilW-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 5 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.75A 2eimJ-2ziuA:
undetectable		 2eimJ-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 5 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.72A 2eimW-2ziuA:
undetectable		 2eimW-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 8 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.78A 2einA-2ziuA:
undetectable
2einJ-2ziuA:
undetectable		 2einA-2ziuA:
18.55
2einJ-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 6 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.69A 2einN-2ziuA:
undetectable
2einW-2ziuA:
undetectable		 2einN-2ziuA:
18.55
2einW-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_1
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		3 / 3 ARG A 414
ASP A 326
ASP A 353
 None
 0.80A 2ejtA-2ziuA:
undetectable		 2ejtA-2ziuA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJP_A_KLNA413_1
(CYTOCHROME P450
113A1)		 2ziu CROSSOVER JUNCTION
ENDONUCLEASE EME1
MUS81 PROTEIN
(Danio
rerio;
Homo
sapiens) 		6 / 12 ALA B 421
LEU B 359
ALA B 358
THR B 311
PHE B 439
GLN A 445
 None
 1.45A 2jjpA-2ziuB:
undetectable		 2jjpA-2ziuB:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 2ziu CROSSOVER JUNCTION
ENDONUCLEASE EME1
(Homo
sapiens) 		3 / 3 LYS B 541
ARG B 534
VAL B 532
 None
 0.86A 2r2vC-2ziuB:
undetectable
2r2vD-2ziuB:
undetectable		 2r2vC-2ziuB:
7.64
2r2vD-2ziuB:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3K_A_SAMA1254_0
(ESSENTIAL FOR
MITOTIC GROWTH 1)		 2ziu CROSSOVER JUNCTION
ENDONUCLEASE EME1
(Homo
sapiens) 		5 / 10 LEU B 269
GLY B 271
LEU B 432
SER B 428
ALA B 433
 None
 0.84A 2v3kA-2ziuB:
undetectable		 2v3kA-2ziuB:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN1_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 6 LEU A 415
ASP A 397
LYS A 412
GLU A 392
 None
 1.25A 2vn1B-2ziuA:
undetectable		 2vn1B-2ziuA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 6 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.77A 2zxwA-2ziuA:
undetectable
2zxwJ-2ziuA:
undetectable		 2zxwA-2ziuA:
18.55
2zxwJ-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 8 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.81A 3abkA-2ziuA:
undetectable
3abkJ-2ziuA:
undetectable		 3abkA-2ziuA:
18.55
3abkJ-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 6 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.74A 3abmA-2ziuA:
undetectable
3abmJ-2ziuA:
undetectable		 3abmA-2ziuA:
18.55
3abmJ-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 8 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.70A 3abmN-2ziuA:
undetectable
3abmW-2ziuA:
undetectable		 3abmN-2ziuA:
18.55
3abmW-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 5 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.58A 3ag1J-2ziuA:
undetectable		 3ag1J-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 6 ILE A 424
MET A 475
THR A 476
LEU A 479
 None
 0.87A 3ag1N-2ziuA:
undetectable
3ag1W-2ziuA:
undetectable		 3ag1N-2ziuA:
18.55
3ag1W-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 6 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.43A 3ag1N-2ziuA:
undetectable
3ag1W-2ziuA:
undetectable		 3ag1N-2ziuA:
18.55
3ag1W-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 5 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.81A 3ag2J-2ziuA:
undetectable		 3ag2J-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 7 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.82A 3ag3A-2ziuA:
undetectable
3ag3J-2ziuA:
undetectable		 3ag3A-2ziuA:
18.55
3ag3J-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 5 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.82A 3ag4J-2ziuA:
undetectable		 3ag4J-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 6 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.78A 3asnA-2ziuA:
undetectable
3asnJ-2ziuA:
undetectable		 3asnA-2ziuA:
18.55
3asnJ-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 6 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.77A 3asoA-2ziuA:
undetectable
3asoJ-2ziuA:
undetectable		 3asoA-2ziuA:
18.55
3asoJ-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 8 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.79A 3asoN-2ziuA:
undetectable
3asoW-2ziuA:
undetectable		 3asoN-2ziuA:
18.55
3asoW-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 2ziu CROSSOVER JUNCTION
ENDONUCLEASE EME1
(Homo
sapiens) 		4 / 7 VAL B 501
ILE B 545
GLY B 546
ARG B 551
 None
 0.85A 3bjwF-2ziuB:
undetectable		 3bjwF-2ziuB:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 2ziu CROSSOVER JUNCTION
ENDONUCLEASE EME1
(Homo
sapiens) 		4 / 7 VAL B 501
ILE B 545
GLY B 546
ARG B 551
 None
 0.80A 3bjwH-2ziuB:
undetectable		 3bjwH-2ziuB:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_B_SAMB501_1
(SPERMIDINE SYNTHASE)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 5 GLN A 346
GLN A 339
ASP A 353
THR A 330
 None
 1.23A 3bwcB-2ziuA:
undetectable		 3bwcB-2ziuA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 7 LEU A 341
GLU A 329
ASP A 361
SER A 468
 None
 1.34A 3dzgA-2ziuA:
2.2		 3dzgA-2ziuA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_B_NCAB302_0
(ADP-RIBOSYL CYCLASE
1)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 7 LEU A 341
GLU A 329
ASP A 361
SER A 468
 None
 1.34A 3dzgB-2ziuA:
undetectable		 3dzgB-2ziuA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA304_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 2ziu MUS81 PROTEIN
CROSSOVER JUNCTION
ENDONUCLEASE EME1
(Danio
rerio;
Homo
sapiens) 		4 / 4 GLN B 561
PRO B 562
VAL A 532
GLU A 534
 None
 0.92A 3huoA-2ziuB:
undetectable		 3huoA-2ziuB:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 6 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.83A 3wg7N-2ziuA:
undetectable
3wg7W-2ziuA:
undetectable		 3wg7N-2ziuA:
18.55
3wg7W-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 2ziu CROSSOVER JUNCTION
ENDONUCLEASE EME1
(Homo
sapiens) 		4 / 6 GLU B 283
GLN B 285
VAL B 312
THR B 311
 None
 1.29A 4lnxA-2ziuB:
undetectable		 4lnxA-2ziuB:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 2ziu CROSSOVER JUNCTION
ENDONUCLEASE EME1
MUS81 PROTEIN
(Danio
rerio;
Homo
sapiens) 		5 / 9 ASP B 464
ALA A 537
GLY B 468
SER B 463
GLY A 548
 None
 1.42A 4mmeA-2ziuB:
undetectable		 4mmeA-2ziuB:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		5 / 12 LEU A 593
VAL A 546
GLY A 548
ALA A 551
LEU A 555
 None
 1.13A 4rrwA-2ziuA:
undetectable		 4rrwA-2ziuA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		5 / 12 LEU A 593
VAL A 546
GLY A 548
ALA A 551
LEU A 555
 None
 1.13A 4rrwB-2ziuA:
undetectable		 4rrwB-2ziuA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		5 / 12 LEU A 593
VAL A 546
GLY A 548
ALA A 551
LEU A 555
 None
 1.13A 4rrzA-2ziuA:
undetectable		 4rrzA-2ziuA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		5 / 12 LEU A 593
VAL A 546
GLY A 548
ALA A 551
LEU A 555
 None
 1.13A 4rrzB-2ziuA:
undetectable		 4rrzB-2ziuA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 7 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.84A 5b1aA-2ziuA:
undetectable
5b1aJ-2ziuA:
undetectable		 5b1aA-2ziuA:
18.55
5b1aJ-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 7 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.84A 5b1bN-2ziuA:
undetectable
5b1bW-2ziuA:
undetectable		 5b1bN-2ziuA:
18.55
5b1bW-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 7 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.84A 5b3sA-2ziuA:
undetectable
5b3sJ-2ziuA:
undetectable		 5b3sA-2ziuA:
18.55
5b3sJ-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 7 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.82A 5b3sN-2ziuA:
undetectable
5b3sW-2ziuA:
undetectable		 5b3sN-2ziuA:
18.55
5b3sW-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 2ziu CROSSOVER JUNCTION
ENDONUCLEASE EME1
(Homo
sapiens) 		5 / 12 GLY B 265
LEU B 261
LYS B 430
LEU B 273
CYH B 437
 None
 1.27A 5emlA-2ziuB:
undetectable		 5emlA-2ziuB:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 2ziu MUS81 PROTEIN
CROSSOVER JUNCTION
ENDONUCLEASE EME1
(Danio
rerio;
Homo
sapiens) 		5 / 12 LEU B 359
GLY A 456
ASP A 455
LEU B 361
ALA B 421
 None
 1.12A 5h5fA-2ziuB:
undetectable		 5h5fA-2ziuB:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		5 / 12 LEU A 593
VAL A 546
GLY A 548
ALA A 551
LEU A 555
 None
 1.17A 5ikrA-2ziuA:
undetectable		 5ikrA-2ziuA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 7 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.71A 5iy5N-2ziuA:
undetectable
5iy5W-2ziuA:
undetectable		 5iy5N-2ziuA:
18.55
5iy5W-2ziuA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 5 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.45A 5w97J-2ziuA:
undetectable		 5w97J-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 5 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.71A 5wauJ-2ziuA:
undetectable		 5wauJ-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 5 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.55A 5x19J-2ziuA:
undetectable		 5x19J-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 5 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.59A 5x1bJ-2ziuA:
undetectable		 5x1bJ-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 5 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.58A 5x1bW-2ziuA:
undetectable		 5x1bW-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 6 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.66A 5x1fA-2ziuA:
undetectable
5x1fJ-2ziuA:
undetectable		 5x1fA-2ziuA:
18.55
5x1fJ-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 5 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.53A 5x1fW-2ziuA:
undetectable		 5x1fW-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 7 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.62A 5xdqA-2ziuA:
undetectable
5xdqJ-2ziuA:
undetectable		 5xdqA-2ziuA:
18.55
5xdqJ-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 7 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.60A 5xdqN-2ziuA:
undetectable
5xdqW-2ziuA:
undetectable		 5xdqN-2ziuA:
18.55
5xdqW-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 7 ILE A 424
MET A 475
THR A 476
LEU A 479
 None
 0.98A 5xdxA-2ziuA:
undetectable
5xdxJ-2ziuA:
undetectable		 5xdxA-2ziuA:
18.55
5xdxJ-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 7 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.80A 5xdxA-2ziuA:
undetectable
5xdxJ-2ziuA:
undetectable		 5xdxA-2ziuA:
18.55
5xdxJ-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 5 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.82A 5z86J-2ziuA:
undetectable		 5z86J-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 6 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.79A 5z86N-2ziuA:
undetectable
5z86W-2ziuA:
undetectable		 5z86N-2ziuA:
18.55
5z86W-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 6 ILE A 424
MET A 475
THR A 476
LEU A 479
 None
 1.03A 5zcoN-2ziuA:
undetectable
5zcoW-2ziuA:
undetectable		 5zcoN-2ziuA:
18.55
5zcoW-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 6 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.77A 5zcoN-2ziuA:
undetectable
5zcoW-2ziuA:
undetectable		 5zcoN-2ziuA:
18.55
5zcoW-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 7 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.81A 5zcpA-2ziuA:
undetectable
5zcpJ-2ziuA:
undetectable		 5zcpA-2ziuA:
18.55
5zcpJ-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 8 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.78A 5zcpN-2ziuA:
undetectable
5zcpW-2ziuA:
undetectable		 5zcpN-2ziuA:
18.55
5zcpW-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 7 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.84A 5zcqA-2ziuA:
undetectable
5zcqJ-2ziuA:
undetectable		 5zcqA-2ziuA:
18.55
5zcqJ-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 2ziu CROSSOVER JUNCTION
ENDONUCLEASE EME1
MUS81 PROTEIN
(Danio
rerio;
Homo
sapiens) 		4 / 5 VAL B 500
LEU B 510
VAL A 561
LEU A 604
 None
 1.02A 6bqgA-2ziuB:
undetectable		 6bqgA-2ziuB:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 5 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.49A 6nknJ-2ziuA:
undetectable		 6nknJ-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 5 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.54A 6nknW-2ziuA:
undetectable		 6nknW-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 7 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.58A 6nmfA-2ziuA:
undetectable
6nmfJ-2ziuA:
undetectable		 6nmfA-2ziuA:
18.55
6nmfJ-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ziu MUS81 PROTEIN
(Danio
rerio) 		4 / 7 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.49A 6nmpA-2ziuA:
undetectable
6nmpJ-2ziuA:
undetectable		 6nmpA-2ziuA:
18.55
6nmpJ-2ziuA:
10.29