SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zjs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 2zjs FAB56 (HEAVY CHAIN)
(Mus
musculus) 		4 / 5 VAL H   2
TYR H  27
ARG H  98
TYR H 108
 None
 0.30A 4m7kH-2zjsH:
23.1		 4m7kH-2zjsH:
75.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 2zjs FAB56 (HEAVY CHAIN)
(Mus
musculus) 		3 / 3 THR H  28
SER H  31
TYR H  32
 None
 0.81A 5jsdA-2zjsH:
2.6		 5jsdA-2zjsH:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 2zjs FAB56 (HEAVY CHAIN)
(Mus
musculus) 		3 / 3 THR H  28
SER H  31
TYR H  32
 None
 0.81A 5jsdB-2zjsH:
2.8		 5jsdB-2zjsH:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 2zjs FAB56 (HEAVY CHAIN)
(Mus
musculus) 		3 / 3 THR H  28
SER H  31
TYR H  32
 None
 0.80A 5jsdC-2zjsH:
2.7		 5jsdC-2zjsH:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 2zjs FAB56 (HEAVY CHAIN)
(Mus
musculus) 		3 / 3 THR H  28
SER H  31
TYR H  32
 None
 0.82A 5jseA-2zjsH:
2.5		 5jseA-2zjsH:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 2zjs FAB56 (HEAVY CHAIN)
(Mus
musculus) 		3 / 3 THR H  28
SER H  31
TYR H  32
 None
 0.81A 5jseB-2zjsH:
2.8		 5jseB-2zjsH:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 2zjs FAB56 (HEAVY CHAIN)
(Mus
musculus) 		3 / 3 THR H  28
SER H  31
TYR H  32
 None
 0.81A 5jseC-2zjsH:
undetectable		 5jseC-2zjsH:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN8_A_ACRA1016_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 2zjs FAB56 (HEAVY CHAIN)
(Mus
musculus) 		4 / 5 ASP H 107
GLY H 104
PRO H 100
TRP H  33
 None
 1.16A 5nn8A-2zjsH:
0.6		 5nn8A-2zjsH:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 2zjs FAB56 (HEAVY CHAIN)
(Mus
musculus) 		4 / 6 ASN H  77
ALA H  24
PRO H  53
TYR H  27
 None
 1.07A 5umd2-2zjsH:
undetectable
5umdF-2zjsH:
undetectable		 5umd2-2zjsH:
18.14
5umdF-2zjsH:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2zjs FAB56 (HEAVY CHAIN)
(Mus
musculus) 		4 / 4 LEU H  52
GLY H  54
SER H  30
SER H  31
 None
 1.22A 5uunA-2zjsH:
undetectable		 5uunA-2zjsH:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB306_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2zjs FAB56 (HEAVY CHAIN)
(Mus
musculus) 		4 / 4 LEU H  52
GLY H  54
SER H  30
SER H  31
 None
 1.18A 5uunB-2zjsH:
undetectable		 5uunB-2zjsH:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 2zjs FAB56 (HEAVY CHAIN)
(Mus
musculus) 		4 / 4 VAL H 127
LEU H 130
ASN H 202
ASP H 213
 None
 1.32A 5vcyA-2zjsH:
undetectable		 5vcyA-2zjsH:
19.94