SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zk9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2zk9 PROTEIN-GLUTAMINASE
(Chryseobacterium
proteolyticum) 		3 / 3 TYR X  82
ASP X  40
ASP X 179
 GOL  X 201 ( 4.7A)
None
None
 0.73A 3ou6B-2zk9X:
undetectable		 3ou6B-2zk9X:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2zk9 PROTEIN-GLUTAMINASE
(Chryseobacterium
proteolyticum) 		3 / 3 THR X  25
HIS X  47
LEU X 163
 None
 0.78A 5axdC-2zk9X:
undetectable		 5axdC-2zk9X:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 2zk9 PROTEIN-GLUTAMINASE
(Chryseobacterium
proteolyticum) 		3 / 3 THR X  97
SER X  89
ASP X 114
 None
 0.73A 5kvaA-2zk9X:
undetectable		 5kvaA-2zk9X:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 2zk9 PROTEIN-GLUTAMINASE
(Chryseobacterium
proteolyticum) 		3 / 3 THR X  97
SER X  89
ASP X 114
 None
 0.74A 5kvaB-2zk9X:
undetectable		 5kvaB-2zk9X:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 2zk9 PROTEIN-GLUTAMINASE
(Chryseobacterium
proteolyticum) 		4 / 6 GLY X  74
THR X  75
ARG X  36
SER X 170
 None
 1.07A 6jogA-2zk9X:
undetectable		 6jogA-2zk9X:
18.69