SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zl3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)		 2zl3 ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT
(Helicobacter
pylori) 		5 / 10 GLY A 101
PHE A 103
LEU A  33
THR A  91
LEU A  63
 None
 1.47A 1a8uA-2zl3A:
undetectable		 1a8uA-2zl3A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_B_BEZB294_0
(CHLOROPEROXIDASE T)		 2zl3 ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT
(Helicobacter
pylori) 		5 / 10 GLY A 101
PHE A 103
LEU A  33
THR A  91
LEU A  63
 None
 1.48A 1a8uB-2zl3A:
undetectable		 1a8uB-2zl3A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		 2zl3 ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT
(Helicobacter
pylori) 		3 / 3 LEU A 191
LEU A 116
SER A 119
 None
 0.65A 1tlmA-2zl3A:
undetectable		 1tlmA-2zl3A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)		 2zl3 ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT
(Helicobacter
pylori) 		4 / 4 LEU A 104
SER A  77
LEU A  63
LEU A  33
 None
 1.04A 1yajA-2zl3A:
undetectable		 1yajA-2zl3A:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_H_TRUH800_1
(GLUTAMATE RECEPTOR 2)		 2zl3 ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT
(Helicobacter
pylori) 		3 / 3 ILE A  78
SER A  44
SER A  40
 None
 0.59A 3iltH-2zl3A:
undetectable		 3iltH-2zl3A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 2zl3 ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT
(Helicobacter
pylori) 		5 / 10 SER A  67
GLY A  35
ILE A  37
LEU A  63
ILE A  45
 None
 1.09A 4dt8B-2zl3A:
undetectable		 4dt8B-2zl3A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_2
(PROTEASE PR5-SQV)		 2zl3 ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT
(Helicobacter
pylori) 		5 / 11 ARG A 113
ALA A  99
ILE A  72
GLY A  75
ILE A  78
 None
 1.16A 5kr2B-2zl3A:
undetectable		 5kr2B-2zl3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_B_PFLB510_1
(PROTON-GATED ION
CHANNEL)		 2zl3 ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT
(Helicobacter
pylori) 		4 / 6 ILE A 121
ALA A 102
LEU A 105
ILE A  65
 None
 0.86A 5mvmB-2zl3A:
undetectable
5mvmC-2zl3A:
undetectable		 5mvmB-2zl3A:
14.36
5mvmC-2zl3A:
14.36