SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zm2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		3 / 3 THR A 320
THR A 318
PRO A 322
 None
 0.86A 1a7yB-2zm2A:
undetectable		 1a7yB-2zm2A:
6.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		3 / 3 ALA A 305
VAL A 300
TRP A 299
 None
 0.96A 1c4dA-2zm2A:
undetectable
1c4dB-2zm2A:
undetectable		 1c4dA-2zm2A:
3.81
1c4dB-2zm2A:
3.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 7 LEU A 243
LEU A 117
SER A 116
VAL A 300
 None
 1.02A 1dvxB-2zm2A:
undetectable		 1dvxB-2zm2A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 5 THR A 197
ASP A 221
HIS A 266
HIS A 180
 None
None
MES  A 504 (-4.0A)
MES  A 504 (-4.2A)
 1.01A 1ei6A-2zm2A:
undetectable		 1ei6A-2zm2A:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_D_PPFD412_1
(PHOSPHONOACETATE
HYDROLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 8 THR A 197
ASP A 221
HIS A 266
HIS A 180
 None
None
MES  A 504 (-4.0A)
MES  A 504 (-4.2A)
 0.99A 1ei6D-2zm2A:
undetectable		 1ei6D-2zm2A:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 4 LEU A 125
VAL A 121
CYH A 118
ALA A 265
 None
 1.09A 1mz9E-2zm2A:
undetectable		 1mz9E-2zm2A:
7.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		5 / 7 LEU A  70
ARG A  76
ASP A 384
LEU A 383
GLY A 380
 MES  A 503 (-3.4A)
MES  A 503 (-3.9A)
MES  A 503 ( 3.9A)
GOL  A 507 ( 4.7A)
None
 1.46A 1n13D-2zm2A:
undetectable
1n13E-2zm2A:
undetectable		 1n13D-2zm2A:
12.81
1n13E-2zm2A:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 8 HIS A 266
ASP A 221
THR A 260
PHE A 262
 MES  A 504 (-4.0A)
None
None
None
 1.16A 1p7lC-2zm2A:
undetectable		 1p7lC-2zm2A:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 8 HIS A 266
ASP A 221
THR A 260
PHE A 262
 MES  A 504 (-4.0A)
None
None
None
 1.15A 1p7lD-2zm2A:
undetectable		 1p7lD-2zm2A:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		3 / 3 THR A 320
THR A 318
PRO A 322
 None
 0.82A 1qfiB-2zm2A:
undetectable		 1qfiB-2zm2A:
6.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 8 HIS A 266
ASP A 221
THR A 260
PHE A 262
 MES  A 504 (-4.0A)
None
None
None
 1.16A 1rg9A-2zm2A:
undetectable		 1rg9A-2zm2A:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 8 HIS A 266
ASP A 221
THR A 260
PHE A 262
 MES  A 504 (-4.0A)
None
None
None
 1.14A 1rg9B-2zm2A:
undetectable		 1rg9B-2zm2A:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 8 HIS A 266
ASP A 221
THR A 260
PHE A 262
 MES  A 504 (-4.0A)
None
None
None
 1.16A 1rg9C-2zm2A:
undetectable		 1rg9C-2zm2A:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 8 HIS A 266
ASP A 221
THR A 260
PHE A 262
 MES  A 504 (-4.0A)
None
None
None
 1.14A 1rg9D-2zm2A:
undetectable		 1rg9D-2zm2A:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 8 PHE A  85
LEU A  73
ASP A 384
THR A  82
 None
None
MES  A 503 ( 3.9A)
None
 1.12A 1rmtD-2zm2A:
undetectable		 1rmtD-2zm2A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 7 GLY A 123
ILE A 131
VAL A 126
PRO A 133
 None
 1.02A 1rxcC-2zm2A:
undetectable		 1rxcC-2zm2A:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 7 GLY A 123
ILE A 131
VAL A 126
PRO A 133
 None
 1.00A 1rxcD-2zm2A:
undetectable		 1rxcD-2zm2A:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 8 GLY A 123
ILE A 131
VAL A 126
PRO A 133
 None
 0.99A 1rxcE-2zm2A:
undetectable		 1rxcE-2zm2A:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 7 GLY A 123
ILE A 131
VAL A 126
PRO A 133
 None
 1.01A 1rxcF-2zm2A:
undetectable		 1rxcF-2zm2A:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 7 GLY A 123
ILE A 131
VAL A 126
PRO A 133
 None
 1.00A 1rxcL-2zm2A:
undetectable		 1rxcL-2zm2A:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		5 / 12 ALA A 265
GLY A 267
SER A 217
ALA A 224
PHE A 262
 None
MES  A 504 (-3.3A)
MES  A 504 ( 2.7A)
None
None
 1.12A 1ve3A-2zm2A:
undetectable		 1ve3A-2zm2A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 7 TRP A 331
GLY A 342
TYR A 326
THR A 220
 MES  A 501 (-4.0A)
None
None
None
 1.16A 2aouB-2zm2A:
undetectable		 2aouB-2zm2A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		5 / 10 THR A 120
LEU A 350
VAL A 279
GLY A 280
VAL A 300
 None
 1.34A 2cp4A-2zm2A:
undetectable		 2cp4A-2zm2A:
25.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		5 / 10 THR A 120
LEU A 350
VAL A 279
GLY A 280
VAL A 303
 None
 1.24A 2cp4A-2zm2A:
undetectable		 2cp4A-2zm2A:
25.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 6 TYR A 215
TRP A 331
ILE A 343
ILE A 345
 GOL  A 505 ( 4.4A)
MES  A 501 (-4.0A)
MES  A 501 (-4.2A)
MES  A 504 ( 3.7A)
 0.22A 2dcfA-2zm2A:
67.4		 2dcfA-2zm2A:
97.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DCF_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		7 / 12 MET A 111
VAL A 177
TRP A 186
TYR A 215
SER A 217
GLY A 344
ILE A 345
 MES  A 504 (-3.8A)
MES  A 504 (-4.4A)
MES  A 504 (-4.0A)
GOL  A 505 ( 4.4A)
MES  A 504 ( 2.7A)
MES  A 501 (-3.5A)
MES  A 504 ( 3.7A)
 0.46A 2dcfA-2zm2A:
67.4		 2dcfA-2zm2A:
97.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_1
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		3 / 3 SER A 240
ASP A 275
ASP A 252
 None
None
SO4  A 509 (-3.5A)
 0.53A 2plwA-2zm2A:
undetectable		 2plwA-2zm2A:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QM9_A_TDZA201_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		5 / 12 VAL A 148
ALA A 218
SER A 183
THR A 179
ARG A 205
 None
None
None
None
SO4  A 512 (-4.1A)
 1.34A 2qm9A-2zm2A:
undetectable		 2qm9A-2zm2A:
21.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		5 / 7 TYR A 215
TRP A 331
ILE A 343
ILE A 345
HIS A 375
 GOL  A 505 ( 4.4A)
MES  A 501 (-4.0A)
MES  A 501 (-4.2A)
MES  A 504 ( 3.7A)
MES  A 501 ( 4.2A)
 0.21A 2zm7A-2zm2A:
67.3		 2zm7A-2zm2A:
97.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZM7_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		6 / 10 MET A 111
TRP A 186
TYR A 215
HIS A 266
GLY A 344
ILE A 345
 MES  A 504 (-3.8A)
MES  A 504 (-4.0A)
GOL  A 505 ( 4.4A)
MES  A 504 (-4.0A)
MES  A 501 (-3.5A)
MES  A 504 ( 3.7A)
 0.31A 2zm7A-2zm2A:
67.3		 2zm7A-2zm2A:
97.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZM8_A_ACAA511_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 8 TYR A 215
TRP A 331
ILE A 343
ILE A 345
 GOL  A 505 ( 4.4A)
MES  A 501 (-4.0A)
MES  A 501 (-4.2A)
MES  A 504 ( 3.7A)
 0.21A 2zm8A-2zm2A:
67.1		 2zm8A-2zm2A:
98.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZM8_A_ACAA512_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		7 / 10 MET A 111
TRP A 186
TYR A 215
SER A 217
HIS A 266
GLY A 344
ILE A 345
 MES  A 504 (-3.8A)
MES  A 504 (-4.0A)
GOL  A 505 ( 4.4A)
MES  A 504 ( 2.7A)
MES  A 504 (-4.0A)
MES  A 501 (-3.5A)
MES  A 504 ( 3.7A)
 0.30A 2zm8A-2zm2A:
67.1		 2zm8A-2zm2A:
98.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZM9_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		5 / 9 TYR A 215
TRP A 331
ILE A 343
GLY A 344
ILE A 345
 GOL  A 505 ( 4.4A)
MES  A 501 (-4.0A)
MES  A 501 (-4.2A)
MES  A 501 (-3.5A)
MES  A 504 ( 3.7A)
 0.18A 2zm9A-2zm2A:
68.2		 2zm9A-2zm2A:
99.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZM9_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		6 / 8 MET A 111
TRP A 186
TYR A 215
HIS A 266
GLY A 344
ILE A 345
 MES  A 504 (-3.8A)
MES  A 504 (-4.0A)
GOL  A 505 ( 4.4A)
MES  A 504 (-4.0A)
MES  A 501 (-3.5A)
MES  A 504 ( 3.7A)
 0.16A 2zm9A-2zm2A:
68.2		 2zm9A-2zm2A:
99.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZMA_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 8 TYR A 215
TRP A 331
ILE A 343
ILE A 345
 GOL  A 505 ( 4.4A)
MES  A 501 (-4.0A)
MES  A 501 (-4.2A)
MES  A 504 ( 3.7A)
 0.21A 2zmaA-2zm2A:
67.3		 2zmaA-2zm2A:
97.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZMA_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		6 / 11 MET A 111
TRP A 186
TYR A 215
SER A 217
GLY A 344
ILE A 345
 MES  A 504 (-3.8A)
MES  A 504 (-4.0A)
GOL  A 505 ( 4.4A)
MES  A 504 ( 2.7A)
MES  A 501 (-3.5A)
MES  A 504 ( 3.7A)
 0.24A 2zmaA-2zm2A:
67.3		 2zmaA-2zm2A:
97.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_D_VD3D2001_1
(VITAMIN D
HYDROXYLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		5 / 12 ILE A  66
LEU A  73
LEU A 382
ILE A 360
THR A 356
 None
 1.09A 3a50D-2zm2A:
undetectable		 3a50D-2zm2A:
24.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A65_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		8 / 12 MET A 111
LYS A 115
VAL A 177
TRP A 186
TYR A 215
SER A 217
GLY A 344
ILE A 345
 MES  A 504 (-3.8A)
MES  A 504 (-3.1A)
MES  A 504 (-4.4A)
MES  A 504 (-4.0A)
GOL  A 505 ( 4.4A)
MES  A 504 ( 2.7A)
MES  A 501 (-3.5A)
MES  A 504 ( 3.7A)
 0.32A 3a65A-2zm2A:
67.9		 3a65A-2zm2A:
97.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A66_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		7 / 10 MET A 111
LYS A 115
TRP A 186
TYR A 215
SER A 217
GLY A 344
ILE A 345
 MES  A 504 (-3.8A)
MES  A 504 (-3.1A)
MES  A 504 (-4.0A)
GOL  A 505 ( 4.4A)
MES  A 504 ( 2.7A)
MES  A 501 (-3.5A)
MES  A 504 ( 3.7A)
 0.21A 3a66A-2zm2A:
67.3		 3a66A-2zm2A:
97.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_B_SAMB270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		5 / 11 ALA A 253
GLY A 263
SER A 270
LEU A 110
SER A 114
 None
 1.06A 3gyqB-2zm2A:
undetectable		 3gyqB-2zm2A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		3 / 3 VAL A  43
SER A  45
LEU A  39
 None
 0.73A 3n8xA-2zm2A:
undetectable		 3n8xA-2zm2A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3N_A_DLUA398_1
(PFV INTEGRASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 8 ASP A 285
GLY A 280
PRO A 290
ARG A 274
 None
None
None
SO4  A 513 (-4.2A)
 0.98A 3s3nA-2zm2A:
undetectable		 3s3nA-2zm2A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T01_A_PPFA503_1
(PHOSPHONOACETATE
HYDROLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 7 THR A 197
ASP A 221
HIS A 266
HIS A 180
 None
None
MES  A 504 (-4.0A)
MES  A 504 (-4.2A)
 0.96A 3t01A-2zm2A:
undetectable		 3t01A-2zm2A:
24.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VWP_A_ACAA503_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		7 / 10 MET A 111
LYS A 115
TRP A 186
TYR A 215
SER A 217
GLY A 344
ILE A 345
 MES  A 504 (-3.8A)
MES  A 504 (-3.1A)
MES  A 504 (-4.0A)
GOL  A 505 ( 4.4A)
MES  A 504 ( 2.7A)
MES  A 501 (-3.5A)
MES  A 504 ( 3.7A)
 0.20A 3vwpA-2zm2A:
68.8		 3vwpA-2zm2A:
97.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VWQ_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		7 / 12 MET A 111
LYS A 115
TRP A 186
TYR A 215
SER A 217
GLY A 344
ILE A 345
 MES  A 504 (-3.8A)
MES  A 504 (-3.1A)
MES  A 504 (-4.0A)
GOL  A 505 ( 4.4A)
MES  A 504 ( 2.7A)
MES  A 501 (-3.5A)
MES  A 504 ( 3.7A)
 0.19A 3vwqA-2zm2A:
68.6		 3vwqA-2zm2A:
97.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VWQ_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		7 / 12 MET A 111
LYS A 115
TYR A 170
TYR A 215
SER A 217
GLY A 344
ILE A 345
 MES  A 504 (-3.8A)
MES  A 504 (-3.1A)
None
GOL  A 505 ( 4.4A)
MES  A 504 ( 2.7A)
MES  A 501 (-3.5A)
MES  A 504 ( 3.7A)
 1.46A 3vwqA-2zm2A:
68.6		 3vwqA-2zm2A:
97.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VWR_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		7 / 11 MET A 111
LYS A 115
TRP A 186
TYR A 215
SER A 217
GLY A 344
ILE A 345
 MES  A 504 (-3.8A)
MES  A 504 (-3.1A)
MES  A 504 (-4.0A)
GOL  A 505 ( 4.4A)
MES  A 504 ( 2.7A)
MES  A 501 (-3.5A)
MES  A 504 ( 3.7A)
 0.19A 3vwrA-2zm2A:
68.7		 3vwrA-2zm2A:
97.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 7 GLY A 123
ILE A 131
VAL A 126
PRO A 133
 None
 0.98A 4e1vB-2zm2A:
undetectable		 4e1vB-2zm2A:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 8 GLY A 123
ILE A 131
VAL A 126
PRO A 133
 None
 0.97A 4e1vD-2zm2A:
undetectable		 4e1vD-2zm2A:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 8 GLY A 123
ILE A 131
VAL A 126
PRO A 133
 None
 0.93A 4e1vG-2zm2A:
undetectable		 4e1vG-2zm2A:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 8 GLY A 123
ILE A 131
VAL A 126
PRO A 133
 None
 0.97A 4e1vH-2zm2A:
undetectable		 4e1vH-2zm2A:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_B_SAMB303_0
(CATECHOL
O-METHYLTRANSFERASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		5 / 12 VAL A 177
GLY A 267
SER A 217
ILE A 255
SER A 270
 MES  A 504 (-4.4A)
MES  A 504 (-3.3A)
MES  A 504 ( 2.7A)
None
None
 1.43A 4xueB-2zm2A:
undetectable		 4xueB-2zm2A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 6 LEU A 243
LEU A 117
SER A 116
VAL A 300
 None
 1.02A 5a6iA-2zm2A:
undetectable		 5a6iA-2zm2A:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		3 / 3 GLU A  41
HIS A  38
ASP A 252
 None
None
SO4  A 509 (-3.5A)
 0.79A 5c0oG-2zm2A:
undetectable		 5c0oG-2zm2A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 8 HIS A 266
ASP A 221
THR A 260
PHE A 262
 MES  A 504 (-4.0A)
None
None
None
 1.17A 5t8sB-2zm2A:
undetectable		 5t8sB-2zm2A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 8 TYR A 149
VAL A 148
ARG A 205
ILE A 164
 None
None
SO4  A 512 (-4.1A)
None
 0.84A 5v0vA-2zm2A:
undetectable		 5v0vA-2zm2A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		5 / 9 LEU A 125
LEU A 117
VAL A 121
GLY A 232
ILE A 255
 None
 0.96A 5vkqC-2zm2A:
undetectable
5vkqD-2zm2A:
undetectable		 5vkqC-2zm2A:
12.50
5vkqD-2zm2A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE
(Flavobacterium
sp.) 		4 / 7 TYR A 198
HIS A   9
LEU A 144
VAL A 141
 None
 1.26A 6g2pA-2zm2A:
undetectable		 6g2pA-2zm2A:
24.67