SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2znv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z95_A_198A501_2 (ANDROGEN RECEPTOR)	2znv	AMSH-LIKE PROTEASE (Homo sapiens)	4 / 6	LEU A 340 LEU A 275 LEU A 433 ILE A 346	None	0.96A	1z95A-2znvA: undetectable	1z95A-2znvA: 19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OAX_D_SNLD4001_2 (MINERALOCORTICOID RECEPTOR)	2znv	AMSH-LIKE PROTEASE (Homo sapiens)	4 / 5	LEU A 282 LEU A 435 CYH A 294 THR A 348	None	1.42A	2oaxD-2znvA: undetectable	2oaxD-2znvA: 20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZR_F_HAEF3004_1 (COLLAGENASE 3)	2znv	AMSH-LIKE PROTEASE (Homo sapiens)	3 / 3	HIS A 410 HIS A 408 HIS A 362	ZN A 1 (-3.2A) ZN A 1 (-3.2A) ZN A 1 ( 3.3A)	0.40A	2ozrF-2znvA: undetectable	2ozrF-2znvA: 20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QPK_A_CUA601_0 (LACCASE-1)	2znv	AMSH-LIKE PROTEASE (Homo sapiens)	4 / 5	HIS A 310 CYH A 298 ILE A 312 LEU A 340	None	0.98A	3qpkA-2znvA: undetectable	3qpkA-2znvA: 16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QB9_D_PARD500_1 (ENHANCED INTRACELLULAR SURVIVAL PROTEIN)	2znv	AMSH-LIKE PROTEASE (Homo sapiens)	4 / 8	THR A 363 SER A 366 ASP A 360 TYR A 322	None EDO A 2 (-3.4A) None None	1.43A	4qb9D-2znvA: undetectable	4qb9D-2znvA: 17.26

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1Z95_A_198A501_2","ANDROGEN RECEPTOR","2znv","AMSH-LIKE PROTEASE","Homo sapiens",4,"LEU A 340;LEU A 275;LEU A 433;ILE A 346","None","0.96A","1z95A-2znvA:undetectable","1z95A-2znvA:19.32"],["2OAX_D_SNLD4001_2","MINERALOCORTICOID RECEPTOR","2znv","AMSH-LIKE PROTEASE","Homo sapiens",4,"LEU A 282;LEU A 435;CYH A 294;THR A 348","None","1.42A","2oaxD-2znvA:undetectable","2oaxD-2znvA:20.68"],["2OZR_F_HAEF3004_1","COLLAGENASE 3","2znv","AMSH-LIKE PROTEASE","Homo sapiens",3,"HIS A 410;HIS A 408;HIS A 362"," ZN A   1 (-3.2A); ZN A   1 (-3.2A); ZN A   1 ( 3.3A)","0.40A","2ozrF-2znvA:undetectable","2ozrF-2znvA:20.67"],["3QPK_A_CUA601_0","LACCASE-1","2znv","AMSH-LIKE PROTEASE","Homo sapiens",4,"HIS A 310;CYH A 298;ILE A 312;LEU A 340","None","0.98A","3qpkA-2znvA:undetectable","3qpkA-2znvA:16.18"],["4QB9_D_PARD500_1","ENHANCED INTRACELLULAR SURVIVAL PROTEIN","2znv","AMSH-LIKE PROTEASE","Homo sapiens",4,"THR A 363;SER A 366;ASP A 360;TYR A 322","None;EDO A   2 (-3.4A);None;None","1.43A","4qb9D-2znvA:undetectable","4qb9D-2znvA:17.26"]]