SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zo6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 2zo6 CYAN-EMITTING
GFP-LIKE PROTEIN,
KUSABIRA-CYAN (KCY)
(Verrillofungia
concinna) 		5 / 10 VAL A  60
VAL A  25
ASN A 133
ILE A  40
LEU A  57
 None
 1.19A 1fe2A-2zo6A:
undetectable		 1fe2A-2zo6A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J3J_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2zo6 CYAN-EMITTING
GFP-LIKE PROTEIN,
KUSABIRA-CYAN (KCY)
(Verrillofungia
concinna) 		5 / 9 ASP A  55
PHE A  54
ILE A  40
ILE A 204
THR A 135
 None
 1.39A 1j3jB-2zo6A:
undetectable		 1j3jB-2zo6A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)		 2zo6 CYAN-EMITTING
GFP-LIKE PROTEIN,
KUSABIRA-CYAN (KCY)
(Verrillofungia
concinna) 		3 / 3 LEU A  50
PHE A  23
ARG A  91
 None
None
GYS  A  63 ( 3.0A)
 0.78A 1xdkB-2zo6A:
undetectable		 1xdkB-2zo6A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_1
(POL PROTEIN)		 2zo6 CYAN-EMITTING
GFP-LIKE PROTEIN,
KUSABIRA-CYAN (KCY)
(Verrillofungia
concinna) 		5 / 11 ILE A 195
ALA A 103
GLY A  16
PHE A  61
VAL A  60
 GYS  A  63 ( 3.7A)
None
None
None
None
 0.94A 2fxdA-2zo6A:
undetectable		 2fxdA-2zo6A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_B_PPFB3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 2zo6 CYAN-EMITTING
GFP-LIKE PROTEIN,
KUSABIRA-CYAN (KCY)
(Verrillofungia
concinna) 		4 / 7 ARG A  66
LYS A  65
HIS A  38
ARG A  91
 GYS  A  63 ( 4.2A)
GYS  A  63 ( 3.6A)
GYS  A  63 ( 3.9A)
GYS  A  63 ( 3.0A)
 1.37A 2rk8B-2zo6A:
undetectable		 2rk8B-2zo6A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CO4_A_GCSA401_1
(CHITINASE)		 2zo6 CYAN-EMITTING
GFP-LIKE PROTEIN,
KUSABIRA-CYAN (KCY)
(Verrillofungia
concinna) 		3 / 3 GLU A 143
HIS A 213
HIS A 189
 GYS  A  63 ( 4.8A)
None
None
 0.93A 3co4A-2zo6A:
undetectable		 3co4A-2zo6A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA2_1
(CYTOCHROME P450 2D6)		 2zo6 CYAN-EMITTING
GFP-LIKE PROTEIN,
KUSABIRA-CYAN (KCY)
(Verrillofungia
concinna) 		5 / 11 THR A 174
SER A 118
LEU A  56
THR A  59
PHE A  23
 None
None
None
GYS  A  63 ( 4.1A)
None
 1.42A 3tbgA-2zo6A:
undetectable		 3tbgA-2zo6A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2zo6 CYAN-EMITTING
GFP-LIKE PROTEIN,
KUSABIRA-CYAN (KCY)
(Verrillofungia
concinna) 		4 / 8 LEU A  57
VAL A 199
VAL A 206
LEU A  50
 None
None
GYS  A  63 ( 4.9A)
None
 0.89A 3v81C-2zo6A:
undetectable		 3v81C-2zo6A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 2zo6 CYAN-EMITTING
GFP-LIKE PROTEIN,
KUSABIRA-CYAN (KCY)
(Verrillofungia
concinna) 		4 / 5 PHE A  54
THR A  45
PHE A  23
ILE A 204
 None
 1.06A 4jx1E-2zo6A:
undetectable		 4jx1E-2zo6A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P68_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 2zo6 CYAN-EMITTING
GFP-LIKE PROTEIN,
KUSABIRA-CYAN (KCY)
(Verrillofungia
concinna) 		5 / 11 ASP A  55
PHE A  54
ILE A  40
ILE A 204
THR A 135
 None
 1.32A 4p68A-2zo6A:
undetectable		 4p68A-2zo6A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2zo6 CYAN-EMITTING
GFP-LIKE PROTEIN,
KUSABIRA-CYAN (KCY)
(Verrillofungia
concinna) 		4 / 8 LEU A  57
VAL A 199
VAL A 206
LEU A  50
 None
None
GYS  A  63 ( 4.9A)
None
 0.87A 4puoC-2zo6A:
undetectable		 4puoC-2zo6A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2zo6 CYAN-EMITTING
GFP-LIKE PROTEIN,
KUSABIRA-CYAN (KCY)
(Verrillofungia
concinna) 		4 / 8 LEU A  57
VAL A 199
VAL A 206
LEU A  50
 None
None
GYS  A  63 ( 4.9A)
None
 0.81A 4pwdA-2zo6A:
undetectable		 4pwdA-2zo6A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2zo6 CYAN-EMITTING
GFP-LIKE PROTEIN,
KUSABIRA-CYAN (KCY)
(Verrillofungia
concinna) 		4 / 8 LEU A  57
VAL A 199
VAL A 206
LEU A  50
 None
None
GYS  A  63 ( 4.9A)
None
 0.94A 4q0bA-2zo6A:
undetectable		 4q0bA-2zo6A:
17.67