SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zp2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 2zp2 KINASE A INHIBITOR
(Bacillus
subtilis) 		4 / 7 TYR A 142
PHE A 152
GLY A 154
GLY A 185
 None
 0.80A 11gsB-2zp2A:
undetectable		 11gsB-2zp2A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2zp2 KINASE A INHIBITOR
(Bacillus
subtilis) 		5 / 12 ILE A 172
GLY A 178
ILE A 160
ILE A 131
LEU A 116
 None
 0.79A 3mb5A-2zp2A:
undetectable		 3mb5A-2zp2A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 2zp2 KINASE A INHIBITOR
(Bacillus
subtilis) 		4 / 8 TYR A 142
PHE A 152
GLY A 154
GLY A 185
 None
 0.77A 3n9jB-2zp2A:
undetectable		 3n9jB-2zp2A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 2zp2 KINASE A INHIBITOR
(Bacillus
subtilis) 		4 / 5 PHE A 224
ILE A 104
GLY A 199
HIS A 134
 None
 1.37A 3r0lD-2zp2A:
undetectable		 3r0lD-2zp2A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_2
(PROTEASE)		 2zp2 KINASE A INHIBITOR
(Bacillus
subtilis) 		5 / 12 VAL A 130
GLY A 199
GLY A 178
ILE A 198
ILE A 104
 None
 1.03A 4q5mA-2zp2A:
undetectable		 4q5mA-2zp2A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 2zp2 KINASE A INHIBITOR
(Bacillus
subtilis) 		4 / 6 GLY A 185
THR A 184
GLN A 183
TYR A 142
 None
 1.27A 6ag0C-2zp2A:
undetectable		 6ag0C-2zp2A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_2
(PROTEASE)		 2zp2 KINASE A INHIBITOR
(Bacillus
subtilis) 		3 / 3 GLY A 113
ASP A 115
ILE A 179
 None
 0.56A 6dgxB-2zp2A:
undetectable		 6dgxB-2zp2A:
22.41