SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zq5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 4 THR A  54
LEU A  53
VAL A  10
LEU A  44
 None
 1.12A 1fbmB-2zq5A:
undetectable		 1fbmB-2zq5A:
7.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2503_0
(FERROCHELATASE)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 4 LEU A 221
PRO A 130
LEU A 218
ARG A 214
 None
 1.41A 1hrkB-2zq5A:
undetectable		 1hrkB-2zq5A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 6 ARG A 179
ALA A  71
ILE A 219
PRO A 128
 None
 1.17A 1oniH-2zq5A:
undetectable
1oniI-2zq5A:
undetectable		 1oniH-2zq5A:
15.42
1oniI-2zq5A:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_B_CHDB500_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 4 LEU A 230
VAL A  96
ILE A  94
TRP A 228
 None
 1.01A 1s9qB-2zq5A:
undetectable		 1s9qB-2zq5A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 4 LEU A 221
PRO A 130
LEU A 218
ARG A 214
 None
 1.44A 2hrcB-2zq5A:
undetectable		 2hrcB-2zq5A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 4 LEU A 221
PRO A 130
LEU A 218
ARG A 214
 None
 1.44A 2pnjB-2zq5A:
undetectable		 2pnjB-2zq5A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 11 LEU A 190
PHE A 280
ALA A 197
ASP A 291
ASP A 288
 None
 1.17A 2q72A-2zq5A:
undetectable		 2q72A-2zq5A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 190
PHE A 280
ALA A 197
ASP A 291
ASP A 288
 None
 1.15A 2qb4A-2zq5A:
0.9		 2qb4A-2zq5A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 ASN A 301
ARG A 304
ASP A 316
 None
 0.98A 2qe6A-2zq5A:
undetectable		 2qe6A-2zq5A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 ASN A 301
ARG A 304
ASP A 316
 None
 0.98A 2qe6B-2zq5A:
undetectable		 2qe6B-2zq5A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RIW_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 10 LEU A  43
LEU A  40
LEU A  69
LEU A 182
ARG A 179
 None
 1.14A 2riwA-2zq5A:
undetectable
2riwB-2zq5A:
undetectable		 2riwA-2zq5A:
23.02
2riwB-2zq5A:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_B_PFNB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 4 TYR A 209
LEU A 239
LEU A 242
HIS A 212
 None
 1.49A 2x7hB-2zq5A:
undetectable		 2x7hB-2zq5A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 6 TYR A 196
ALA A 197
LEU A 200
ASN A 232
 None
 0.75A 3b6hB-2zq5A:
undetectable		 3b6hB-2zq5A:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 6 LEU A  16
SER A  19
ARG A  62
LEU A  69
 None
 1.04A 3f33A-2zq5A:
undetectable		 3f33A-2zq5A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 6 LEU A  16
SER A  19
LEU A  23
LEU A  69
 None
 0.97A 3f33A-2zq5A:
undetectable		 3f33A-2zq5A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  98
THR A 104
PHE A 237
ARG A 101
LEU A  99
 None
 1.19A 3iv6C-2zq5A:
undetectable		 3iv6C-2zq5A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 ALA A 249
LEU A 236
PHE A 237
THR A 245
LEU A 242
 None
 1.02A 3mteB-2zq5A:
undetectable		 3mteB-2zq5A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_C_OBNC1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 11 PRO A 115
ASP A 114
LEU A 111
VAL A 328
ALA A 329
 None
 1.11A 3n23C-2zq5A:
undetectable		 3n23C-2zq5A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAV_A_RAVA183_1
(FERRITIN LIGHT CHAIN)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 6 LEU A  16
SER A  19
ARG A  62
LEU A  69
 None
 1.05A 3ravA-2zq5A:
undetectable		 3ravA-2zq5A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 7 ASN A  61
LEU A  65
ARG A 179
TYR A 187
 None
 0.99A 4cp3A-2zq5A:
undetectable
4cp3B-2zq5A:
undetectable		 4cp3A-2zq5A:
16.39
4cp3B-2zq5A:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 TYR A  36
ARG A 211
SER A 181
 None
 1.18A 4lf7I-2zq5A:
undetectable
4lf7J-2zq5A:
undetectable		 4lf7I-2zq5A:
18.18
4lf7J-2zq5A:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 TYR A  36
ARG A 211
SER A 181
 None
 1.18A 4lf8I-2zq5A:
undetectable
4lf8J-2zq5A:
undetectable		 4lf8I-2zq5A:
18.18
4lf8J-2zq5A:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 5 TYR A  82
LEU A 124
PRO A 132
LEU A  74
 None
 1.27A 5eshA-2zq5A:
undetectable		 5eshA-2zq5A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_E_ASCE1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 7 HIS A 117
HIS A 108
ILE A  94
TYR A 332
 None
 1.25A 5kkzC-2zq5A:
undetectable
5kkzE-2zq5A:
undetectable		 5kkzC-2zq5A:
20.50
5kkzE-2zq5A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_K_ASCK1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 7 HIS A 108
ILE A  94
TYR A 332
HIS A 117
 None
 1.26A 5kkzK-2zq5A:
undetectable
5kkzQ-2zq5A:
undetectable		 5kkzK-2zq5A:
22.88
5kkzQ-2zq5A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 7 HIS A 117
HIS A 108
ILE A  94
TYR A 332
 None
 1.25A 5kkzM-2zq5A:
undetectable
5kkzO-2zq5A:
undetectable		 5kkzM-2zq5A:
20.50
5kkzO-2zq5A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_2
(CYTOCHROME P450 3A5)		 2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 5 ARG A 295
PHE A 300
PHE A 237
LEU A 384
 None
 1.26A 5veuH-2zq5A:
undetectable		 5veuH-2zq5A:
20.93