SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zqb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 2zqb RIBONUCLEASE HI
(Shewanella
oneidensis) 		3 / 3 GLN A  74
THR A  11
TRP A 120
 None
 0.95A 2rctA-2zqbA:
undetectable		 2rctA-2zqbA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 2zqb RIBONUCLEASE HI
(Shewanella
oneidensis) 		5 / 12 THR A  44
SER A  73
SER A  71
THR A  11
GLY A  23
 None
 1.22A 2x2iA-2zqbA:
undetectable		 2x2iA-2zqbA:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 2zqb RIBONUCLEASE HI
(Shewanella
oneidensis) 		5 / 12 THR A  44
SER A  73
SER A  71
THR A  11
GLY A  23
 None
 1.24A 2x2iC-2zqbA:
undetectable		 2x2iC-2zqbA:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 2zqb RIBONUCLEASE HI
(Shewanella
oneidensis) 		4 / 5 TYR A  30
LYS A   5
LEU A  61
GLU A  63
 None
 1.21A 4olaA-2zqbA:
5.9		 4olaA-2zqbA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLB_A_TRPA902_0
(PROTEIN ARGONAUTE-2)		 2zqb RIBONUCLEASE HI
(Shewanella
oneidensis) 		4 / 5 TYR A  30
LYS A   5
LEU A  61
GLU A  63
 None
 1.37A 4olbA-2zqbA:
5.7		 4olbA-2zqbA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 2zqb RIBONUCLEASE HI
(Shewanella
oneidensis) 		4 / 5 TYR A  30
LYS A   5
LEU A  61
GLU A  63
 None
 1.24A 4z4dA-2zqbA:
6.7		 4z4dA-2zqbA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 2zqb RIBONUCLEASE HI
(Shewanella
oneidensis) 		4 / 5 TYR A  30
LYS A   5
LEU A  61
GLU A  63
 None
 1.34A 5js1A-2zqbA:
3.6		 5js1A-2zqbA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA901_0
(PROTEIN ARGONAUTE-2)		 2zqb RIBONUCLEASE HI
(Shewanella
oneidensis) 		4 / 5 TYR A  30
LYS A   5
LEU A  61
GLU A  63
 None
 1.38A 6cbdA-2zqbA:
5.5		 6cbdA-2zqbA:
11.46