SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zr1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 2zr1 AGGLUTININ-1 CHAIN A
(Abrus
precatorius) 		7 / 9 PHE A  86
GLY A 110
TYR A 112
ILE A 158
ALA A 162
GLU A 163
ARG A 166
 None
 0.44A 1mrgA-2zr1A:
33.4		 1mrgA-2zr1A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 2zr1 AGGLUTININ-1 CHAIN A
(Abrus
precatorius) 		5 / 8 GLY A 110
TYR A 112
ILE A 158
GLU A 163
ARG A 166
 None
 0.27A 1mrjA-2zr1A:
33.7		 1mrjA-2zr1A:
35.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2002_1
(SERUM ALBUMIN)		 2zr1 AGGLUTININ-1 CHAIN A
(Abrus
precatorius) 		4 / 9 ILE A 158
PHE A  86
ALA A  76
VAL A  74
 None
 0.77A 2vufA-2zr1A:
undetectable		 2vufA-2zr1A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_1
(RENIN)		 2zr1 AGGLUTININ-1 CHAIN A
(Abrus
precatorius) 		5 / 12 GLY A  66
THR A  70
LEU A  97
SER A  92
ALA A  93
 None
 1.22A 3d91A-2zr1A:
undetectable		 3d91A-2zr1A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_2
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT
LIGHT CHAIN OF
ANTIBODY FAB
FRAGMENT)		 2zr1 AGGLUTININ-1 CHAIN A
(Abrus
precatorius) 		4 / 5 TYR A  16
ILE A  63
LEU A  55
PHE A   6
 None
 1.27A 3ls4L-2zr1A:
undetectable		 3ls4L-2zr1A:
22.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)		 2zr1 AGGLUTININ-1 CHAIN A
(Abrus
precatorius) 		6 / 10 ASN A 111
TYR A 112
ILE A 158
ALA A 162
GLU A 163
ARG A 166
 None
 0.99A 3u6tA-2zr1A:
33.5		 3u6tA-2zr1A:
33.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_B_SFYB806_0
(SEPIAPTERIN
REDUCTASE)		 2zr1 AGGLUTININ-1 CHAIN A
(Abrus
precatorius) 		5 / 11 LEU A  38
SER A 201
LEU A 200
PHE A 167
ALA A  72
 None
 1.48A 4hwkB-2zr1A:
undetectable		 4hwkB-2zr1A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_C_SFYC804_0
(SEPIAPTERIN
REDUCTASE)		 2zr1 AGGLUTININ-1 CHAIN A
(Abrus
precatorius) 		5 / 12 LEU A  38
SER A 201
LEU A 200
PHE A 167
ALA A  72
 None
 1.46A 4hwkC-2zr1A:
undetectable		 4hwkC-2zr1A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_D_SFYD803_0
(SEPIAPTERIN
REDUCTASE)		 2zr1 AGGLUTININ-1 CHAIN A
(Abrus
precatorius) 		5 / 11 LEU A  38
SER A 201
LEU A 200
PHE A 167
ALA A  72
 None
 1.49A 4hwkD-2zr1A:
undetectable		 4hwkD-2zr1A:
20.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O0O_A_URFA303_1
(RRNA N-GLYCOSIDASE)		 2zr1 AGGLUTININ-1 CHAIN A
(Abrus
precatorius) 		4 / 5 TYR A  73
TYR A 112
ILE A 158
ARG A 166
 None
 0.57A 4o0oA-2zr1A:
33.6		 4o0oA-2zr1A:
33.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 2zr1 AGGLUTININ-1 CHAIN A
(Abrus
precatorius) 		3 / 3 GLU A 163
ALA A 164
PHE A 167
 None
 0.63A 4v1fA-2zr1A:
undetectable		 4v1fA-2zr1A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 2zr1 AGGLUTININ-1 CHAIN A
(Abrus
precatorius) 		3 / 3 GLU A 163
ALA A 164
PHE A 167
 None
 0.59A 4v1fC-2zr1A:
undetectable		 4v1fC-2zr1A:
17.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 2zr1 AGGLUTININ-1 CHAIN A
(Abrus
precatorius) 		8 / 9 TYR A  73
PHE A  86
GLY A 110
TYR A 112
ILE A 158
ALA A 162
GLU A 163
ARG A 166
 None
 0.43A 4yp2B-2zr1A:
24.7		 4yp2B-2zr1A:
33.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 2zr1 AGGLUTININ-1 CHAIN A
(Abrus
precatorius) 		8 / 9 TYR A  73
PHE A  86
GLY A 110
TYR A 112
ILE A 158
ALA A 162
GLU A 163
ARG A 166
 None
 0.43A 5cf9B-2zr1A:
33.6		 5cf9B-2zr1A:
33.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)		 2zr1 AGGLUTININ-1 CHAIN A
(Abrus
precatorius) 		5 / 12 LEU A 130
LEU A  65
ILE A   4
ALA A 164
LEU A  23
 None
 1.38A 5ienA-2zr1A:
undetectable		 5ienA-2zr1A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)		 2zr1 AGGLUTININ-1 CHAIN A
(Abrus
precatorius) 		5 / 12 LEU A  97
PHE A  98
LEU A 140
PHE A  86
LEU A 115
 None
 1.07A 5iepA-2zr1A:
undetectable		 5iepA-2zr1A:
19.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z3J_A_NCAA302_0
(ABRIN A-CHAIN)		 2zr1 AGGLUTININ-1 CHAIN A
(Abrus
precatorius) 		6 / 6 TYR A  73
VAL A  74
TYR A 112
ILE A 158
GLU A 163
ARG A 166
 None
 0.47A 5z3jA-2zr1A:
40.2		 5z3jA-2zr1A:
64.53