SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zrr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_2
(MINERALOCORTICOID
RECEPTOR)		 2zrr MUNDTICIN KS
IMMUNITY PROTEIN
(Enterococcus
mundtii) 		3 / 3 LEU A  24
LEU A  45
MET A  62
 None
 0.62A 1ya3B-2zrrA:
undetectable		 1ya3B-2zrrA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2zrr MUNDTICIN KS
IMMUNITY PROTEIN
(Enterococcus
mundtii) 		4 / 7 LYS A  84
LEU A  85
LEU A  24
LEU A  41
 None
 0.76A 4wg0B-2zrrA:
undetectable
4wg0C-2zrrA:
undetectable		 4wg0B-2zrrA:
10.64
4wg0C-2zrrA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2zrr MUNDTICIN KS
IMMUNITY PROTEIN
(Enterococcus
mundtii) 		4 / 7 LEU A  24
LEU A  41
LYS A  84
LEU A  85
 None
 0.70A 4wg0L-2zrrA:
undetectable
4wg0M-2zrrA:
undetectable		 4wg0L-2zrrA:
10.64
4wg0M-2zrrA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZOW_A_CLMA500_0
(MULTIDRUG
TRANSPORTER MDFA)		 2zrr MUNDTICIN KS
IMMUNITY PROTEIN
(Enterococcus
mundtii) 		5 / 11 LEU A  77
LEU A  45
LEU A  88
LEU A  85
ILE A  66
 None
 0.93A 4zowA-2zrrA:
undetectable		 4zowA-2zrrA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 2zrr MUNDTICIN KS
IMMUNITY PROTEIN
(Enterococcus
mundtii) 		4 / 7 LEU A  77
LEU A  37
LEU A  88
MET A  89
 None
 0.74A 6g9bA-2zrrA:
undetectable
6g9bB-2zrrA:
undetectable		 6g9bA-2zrrA:
23.14
6g9bB-2zrrA:
18.33