SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zs0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXE_B_1FLB2001_1 (SERUM ALBUMIN)	2zs0	EXTRACELLULAR GIANT HEMOGLOBIN MAJOR GLOBIN SUBUNIT B1 (Oligobrachia mashikoi)	5 / 12	ILE D 35 PHE D 61 VAL D 68 LEU D 110 SER D 43	None None HEM D 200 (-4.0A) HEM D 200 (-3.8A) None	1.24A	2bxeB-2zs0D: 2.7	2bxeB-2zs0D: 13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CZV_A_AZMA263_1 (CARBONIC ANHYDRASE 13)	2zs0	EXTRACELLULAR GIANT HEMOGLOBIN MAJOR GLOBIN SUBUNIT B1 (Oligobrachia mashikoi)	5 / 12	HIS D 96 PHE D 50 VAL D 68 VAL D 107 VAL D 45	HEM D 200 (-3.3A) HEM D 200 ( 4.3A) HEM D 200 (-4.0A) HEM D 200 (-3.9A) HEM D 200 ( 4.9A)	1.08A	3czvA-2zs0D: undetectable 3czvB-2zs0D: undetectable	3czvA-2zs0D: 19.38 3czvB-2zs0D: 19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	2zs0	EXTRACELLULAR GIANT HEMOGLOBIN MAJOR GLOBIN SUBUNIT B1 (Oligobrachia mashikoi)	5 / 12	PHE D 36 HIS D 96 ILE D 141 VAL D 118 ILE D 69	OXY D 201 (-4.5A) HEM D 200 (-3.3A) HEM D 200 (-4.5A) None None	1.30A	3sp9A-2zs0D: undetectable	3sp9A-2zs0D: 19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VNS_A_DVAA602_0 (NRPS ADENYLATION PROTEIN CYTC1)	2zs0	EXTRACELLULAR GIANT HEMOGLOBIN MAJOR GLOBIN SUBUNIT B1 (Oligobrachia mashikoi)	4 / 7	PHE D 40 ASP D 37 PHE D 36 GLY D 54	None None OXY D 201 (-4.5A) None	0.94A	3vnsA-2zs0D: undetectable	3vnsA-2zs0D: 13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_B_W9TB513_1 (HEMOLYTIC LECTIN CEL-III)	2zs0	EXTRACELLULAR GIANT HEMOGLOBIN MAJOR GLOBIN SUBUNIT B1 (Oligobrachia mashikoi)	4 / 6	THR D 80 ASN D 81 CYH D 85 ILE D 74	None	1.16A	3w9tB-2zs0D: undetectable	3w9tB-2zs0D: 16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O2B_B_LOCB503_2 (TUBULIN BETA-2B CHAIN)	2zs0	EXTRACELLULAR GIANT HEMOGLOBIN MAJOR GLOBIN SUBUNIT B1 (Oligobrachia mashikoi)	5 / 12	LEU D 110 ALA D 113 ALA D 72 ILE D 137 ILE D 76	HEM D 200 (-3.8A) None HEM D 200 ( 4.7A) None None	1.07A	4o2bB-2zs0D: undetectable	4o2bB-2zs0D: 16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E4D_A_BEZA201_0 (HYDROXYNITRILE LYASE)	2zs0	EXTRACELLULAR GIANT HEMOGLOBIN MAJOR GLOBIN SUBUNIT B1 (Oligobrachia mashikoi)	5 / 9	VAL D 68 VAL D 65 PHE D 61 PHE D 39 LEU D 110	HEM D 200 (-4.0A) None None HEM D 200 ( 4.7A) HEM D 200 (-3.8A)	1.41A	5e4dA-2zs0D: undetectable	5e4dA-2zs0D: 23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ENT_C_MIYC901_1 (MULTIDRUG EFFLUX PUMP SUBUNIT ACRB,MULTIDRUG EFFLUX PUMP SUBUNIT ACRB)	2zs0	EXTRACELLULAR GIANT HEMOGLOBIN MAJOR GLOBIN SUBUNIT B1 (Oligobrachia mashikoi)	5 / 9	GLN D 64 GLY D 32 GLU D 28 ILE D 114 ALA D 113	HEM D 200 ( 3.6A) None None None None	1.30A	5entC-2zs0D: undetectable	5entC-2zs0D: 14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MIO_B_LOCB502_1 (TUBULIN BETA CHAIN)	2zs0	EXTRACELLULAR GIANT HEMOGLOBIN MAJOR GLOBIN SUBUNIT B1 (Oligobrachia mashikoi)	5 / 12	LEU D 110 ALA D 113 ALA D 72 ILE D 137 ILE D 76	HEM D 200 (-3.8A) None HEM D 200 ( 4.7A) None None	1.03A	5mioB-2zs0D: undetectable	5mioB-2zs0D: 16.39

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2BXE_B_1FLB2001_1","SERUM ALBUMIN","2zs0","EXTRACELLULAR GIANT HEMOGLOBIN MAJOR GLOBIN SUBUNIT B1","Oligobrachia mashikoi",5,"ILE D  35;PHE D  61;VAL D  68;LEU D 110;SER D  43","None;None;HEM D 200 (-4.0A);HEM D 200 (-3.8A);None","1.24A","2bxeB-2zs0D:2.7","2bxeB-2zs0D:13.28"],["3CZV_A_AZMA263_1","CARBONIC ANHYDRASE 13;CARBONIC ANHYDRASE 13","2zs0","EXTRACELLULAR GIANT HEMOGLOBIN MAJOR GLOBIN SUBUNIT B1","Oligobrachia mashikoi",5,"HIS D  96;PHE D  50;VAL D  68;VAL D 107;VAL D  45","HEM D 200 (-3.3A);HEM D 200 ( 4.3A);HEM D 200 (-4.0A);HEM D 200 (-3.9A);HEM D 200 ( 4.9A)","1.08A","3czvA-2zs0D:undetectable;3czvB-2zs0D:undetectable","3czvA-2zs0D:19.38;3czvB-2zs0D:19.38"],["3SP9_A_IL2A901_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA","2zs0","EXTRACELLULAR GIANT HEMOGLOBIN MAJOR GLOBIN SUBUNIT B1","Oligobrachia mashikoi",5,"PHE D  36;HIS D  96;ILE D 141;VAL D 118;ILE D  69","OXY D 201 (-4.5A);HEM D 200 (-3.3A);HEM D 200 (-4.5A);None;None","1.30A","3sp9A-2zs0D:undetectable","3sp9A-2zs0D:19.26"],["3VNS_A_DVAA602_0","NRPS ADENYLATION PROTEIN CYTC1","2zs0","EXTRACELLULAR GIANT HEMOGLOBIN MAJOR GLOBIN SUBUNIT B1","Oligobrachia mashikoi",4,"PHE D  40;ASP D  37;PHE D  36;GLY D  54","None;None;OXY D 201 (-4.5A);None","0.94A","3vnsA-2zs0D:undetectable","3vnsA-2zs0D:13.60"],["3W9T_B_W9TB513_1","HEMOLYTIC LECTIN CEL-III","2zs0","EXTRACELLULAR GIANT HEMOGLOBIN MAJOR GLOBIN SUBUNIT B1","Oligobrachia mashikoi",4,"THR D  80;ASN D  81;CYH D  85;ILE D  74","None","1.16A","3w9tB-2zs0D:undetectable","3w9tB-2zs0D:16.13"],["4O2B_B_LOCB503_2","TUBULIN BETA-2B CHAIN","2zs0","EXTRACELLULAR GIANT HEMOGLOBIN MAJOR GLOBIN SUBUNIT B1","Oligobrachia mashikoi",5,"LEU D 110;ALA D 113;ALA D  72;ILE D 137;ILE D  76","HEM D 200 (-3.8A);None;HEM D 200 ( 4.7A);None;None","1.07A","4o2bB-2zs0D:undetectable","4o2bB-2zs0D:16.39"],["5E4D_A_BEZA201_0","HYDROXYNITRILE LYASE","2zs0","EXTRACELLULAR GIANT HEMOGLOBIN MAJOR GLOBIN SUBUNIT B1","Oligobrachia mashikoi",5,"VAL D  68;VAL D  65;PHE D  61;PHE D  39;LEU D 110","HEM D 200 (-4.0A);None;None;HEM D 200 ( 4.7A);HEM D 200 (-3.8A)","1.41A","5e4dA-2zs0D:undetectable","5e4dA-2zs0D:23.08"],["5ENT_C_MIYC901_1","MULTIDRUG EFFLUX PUMP SUBUNIT ACRB,MULTIDRUG EFFLUX PUMP SUBUNIT ACRB","2zs0","EXTRACELLULAR GIANT HEMOGLOBIN MAJOR GLOBIN SUBUNIT B1","Oligobrachia mashikoi",5,"GLN D  64;GLY D  32;GLU D  28;ILE D 114;ALA D 113","HEM D 200 ( 3.6A);None;None;None;None","1.30A","5entC-2zs0D:undetectable","5entC-2zs0D:14.64"],["5MIO_B_LOCB502_1","TUBULIN BETA CHAIN","2zs0","EXTRACELLULAR GIANT HEMOGLOBIN MAJOR GLOBIN SUBUNIT B1","Oligobrachia mashikoi",5,"LEU D 110;ALA D 113;ALA D  72;ILE D 137;ILE D  76","HEM D 200 (-3.8A);None;HEM D 200 ( 4.7A);None;None","1.03A","5mioB-2zs0D:undetectable","5mioB-2zs0D:16.39"]]