SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zs6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 2zs6 HEMAGGLUTININ
COMPONENTS HA3
(Clostridium
botulinum) 		4 / 7 PHE A  91
TYR A 141
TYR A  68
PRO A  67
 None
 1.21A 2q6kA-2zs6A:
undetectable		 2q6kA-2zs6A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 2zs6 HEMAGGLUTININ
COMPONENTS HA3
(Clostridium
botulinum) 		4 / 5 TYR A 124
ILE A 126
TYR A  69
ILE A  80
 None
 1.05A 4jtpA-2zs6A:
undetectable		 4jtpA-2zs6A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_B_SALB203_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 2zs6 HEMAGGLUTININ
COMPONENTS HA3
(Clostridium
botulinum) 		4 / 6 GLY A 146
TYR A 147
LEU A  43
VAL A  56
 None
 0.92A 5x80A-2zs6A:
undetectable
5x80B-2zs6A:
undetectable		 5x80A-2zs6A:
18.69
5x80B-2zs6A:
18.69