SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zsc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2UZ2_A_ACTA1123_0 (XENAVIDIN)	2zsc	TAMAVIDIN2 (Pleurotus cornucopiae)	6 / 7	ASN A 14 LEU A 16 SER A 18 TYR A 34 VAL A 38 TRP A 80	BTN A 301 (-3.4A) BTN A 301 ( 4.9A) BTN A 301 (-2.6A) BTN A 301 (-4.5A) BTN A 301 (-4.8A) BTN A 301 (-4.8A)	0.29A	2uz2A-2zscA: 15.8	2uz2A-2zscA: 29.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SI7_A_ACTA4_0 (CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR)	2zsc	TAMAVIDIN2 (Pleurotus cornucopiae)	4 / 4	LEU A 63 GLY A 64 GLY A 82 THR A 94	None	0.95A	3si7A-2zscA: undetectable	3si7A-2zscA: 19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HLW_A_TESA1001_1 (ANDROGEN RECEPTOR)	2zsc	TAMAVIDIN2 (Pleurotus cornucopiae)	5 / 12	LEU A 30 ASN A 25 GLY A 28 VAL A 61 THR A 9	None None None GOL A1810 (-4.5A) None	1.49A	4hlwA-2zscA: undetectable	4hlwA-2zscA: 19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X20_D_LOCD502_1 (TUBULIN ALPHA CHAIN TUBULIN BETA CHAIN)	2zsc	TAMAVIDIN2 (Pleurotus cornucopiae)	3 / 3	SER A 81 ALA A 62 VAL A 61	None None GOL A1810 (-4.5A)	0.61A	4x20C-2zscA: undetectable	4x20C-2zscA: 15.40

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2UZ2_A_ACTA1123_0","XENAVIDIN","2zsc","TAMAVIDIN2","Pleurotus cornucopiae",6,"ASN A  14;LEU A  16;SER A  18;TYR A  34;VAL A  38;TRP A  80","BTN A 301 (-3.4A);BTN A 301 ( 4.9A);BTN A 301 (-2.6A);BTN A 301 (-4.5A);BTN A 301 (-4.8A);BTN A 301 (-4.8A)","0.29A","2uz2A-2zscA:15.8","2uz2A-2zscA:29.05"],["3SI7_A_ACTA4_0","CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR","2zsc","TAMAVIDIN2","Pleurotus cornucopiae",4,"LEU A  63;GLY A  64;GLY A  82;THR A  94","None","0.95A","3si7A-2zscA:undetectable","3si7A-2zscA:19.79"],["4HLW_A_TESA1001_1","ANDROGEN RECEPTOR","2zsc","TAMAVIDIN2","Pleurotus cornucopiae",5,"LEU A  30;ASN A  25;GLY A  28;VAL A  61;THR A   9","None;None;None;GOL A1810 (-4.5A);None","1.49A","4hlwA-2zscA:undetectable","4hlwA-2zscA:19.46"],["4X20_D_LOCD502_1","TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN","2zsc","TAMAVIDIN2","Pleurotus cornucopiae",3,"SER A  81;ALA A  62;VAL A  61","None;None;GOL A1810 (-4.5A)","0.61A","4x20C-2zscA:undetectable","4x20C-2zscA:15.40"]]