SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zt9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5

(Nostoc
sp.
PCC
7120)
4 / 6 ASN A  31
ALA G  24
GLY G  20
TYR G  23
None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
1.00A 1c8lA-2zt9A:
undetectable
1c8lA-2zt9A:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVT_A_FLPA125_1
(TRANSTHYRETIN)
2zt9 CYTOCHROME B6-F
COMPLEX SUBUNIT 4

(Nostoc
sp.
PCC
7120)
4 / 8 LEU B 149
LEU B  96
LEU B  91
SER B  90
None
0.98A 1dvtA-2zt9B:
undetectable
1dvtB-2zt9B:
undetectable
1dvtA-2zt9B:
23.31
1dvtB-2zt9B:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5

(Nostoc
sp.
PCC
7120)
4 / 6 ASN A  31
ALA G  24
GLY G  20
TYR G  23
None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
1.01A 1gfzA-2zt9A:
undetectable
1gfzA-2zt9A:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5

(Nostoc
sp.
PCC
7120)
4 / 6 ASN A  31
ALA G  24
GLY G  20
TYR G  23
None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
1.04A 1l5qA-2zt9A:
undetectable
1l5qA-2zt9A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5

(Nostoc
sp.
PCC
7120)
4 / 6 ASN A  31
ALA G  24
GLY G  20
TYR G  23
None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
1.03A 1l5qB-2zt9A:
undetectable
1l5qB-2zt9A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5

(Nostoc
sp.
PCC
7120)
4 / 6 ASN A  31
ALA G  24
GLY G  20
TYR G  23
None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
1.02A 1l7xA-2zt9A:
undetectable
1l7xA-2zt9A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5

(Nostoc
sp.
PCC
7120)
4 / 6 ASN A  31
ALA G  24
GLY G  20
TYR G  23
None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
1.06A 1l7xB-2zt9A:
undetectable
1l7xB-2zt9A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_D_MTXD354_1
(PTERIDINE REDUCTASE
1)
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 4

(Nostoc
sp.
PCC
7120)
5 / 12 SER A  91
PRO B  77
TYR B  80
LEU A 138
TYR A 183
None
None
None
HEM  A 301 ( 4.2A)
None
1.50A 1p33D-2zt9A:
undetectable
1p33D-2zt9A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)
2zt9 CYTOCHROME B6-F
COMPLEX SUBUNIT 4
CYTOCHROME B6-F
COMPLEX SUBUNIT 8

(Nostoc
sp.
PCC
7120;
Nostoc
sp.
PCC
7120)
3 / 3 SER H  10
VAL B  56
LEU B  57
None
0.56A 1yajG-2zt9H:
undetectable
1yajG-2zt9H:
4.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA501_1
(CYTOCHROME P450 2B4)
2zt9 CYTOCHROME B6-F
COMPLEX SUBUNIT 4
CYTOCHROME B6-F
COMPLEX SUBUNIT 5
CYTOCHROME B6-F
COMPLEX SUBUNIT 7

(Nostoc
sp.
PCC
7120)
4 / 7 LEU F  10
PHE F  13
GLY G  12
ILE B 145
None
0.92A 2bdmA-2zt9F:
undetectable
2bdmA-2zt9F:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_A_IPHA2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 4

(Nostoc
sp.
PCC
7120;
Nostoc
sp.
PCC
7120)
4 / 5 HIS B  24
PRO A 214
TYR B  27
PRO B   7
None
1.50A 2ombA-2zt9B:
undetectable
2ombB-2zt9B:
undetectable
2ombA-2zt9B:
19.81
2ombB-2zt9B:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA142_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)
2zt9 CYTOCHROME B6
(Nostoc
sp.
PCC
7120)
4 / 5 GLU A 156
PRO A 155
ILE A 165
GLY A 162
None
1.15A 2qeuA-2zt9A:
undetectable
2qeuC-2zt9A:
undetectable
2qeuA-2zt9A:
20.83
2qeuC-2zt9A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5

(Nostoc
sp.
PCC
7120;
Nostoc
sp.
PCC
7120)
3 / 3 PRO A  28
ASN G  33
ARG G  31
None
0.97A 2qeuB-2zt9A:
undetectable
2qeuB-2zt9A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_A_BEZA1162_0
(PEROXIREDOXIN-5)
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 4

(Nostoc
sp.
PCC
7120;
Nostoc
sp.
PCC
7120)
5 / 10 PRO B   7
PRO A  27
GLY B  28
LEU B  18
GLY B  23
None
1.44A 2vl2A-2zt9B:
undetectable
2vl2C-2zt9B:
undetectable
2vl2A-2zt9B:
22.11
2vl2C-2zt9B:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_D_TOPD1158_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 4

(Nostoc
sp.
PCC
7120)
5 / 10 ILE B  51
ALA B  53
LEU A  81
ILE A  85
PHE B  48
None
1.14A 2w9sD-2zt9B:
undetectable
2w9sD-2zt9B:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_F_TOPF1159_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 4

(Nostoc
sp.
PCC
7120)
5 / 10 ILE B  51
ALA B  53
LEU A  81
ILE A  85
PHE B  48
None
1.13A 2w9sF-2zt9B:
undetectable
2w9sF-2zt9B:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1050_2
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)
2zt9 CYTOCHROME B6-F
COMPLEX IRON-SULFUR
SUBUNIT 1

(Nostoc
sp.
PCC
7120)
4 / 6 TYR D 133
TRP D 177
TRP D 178
THR D  89
None
1.46A 2x2iB-2zt9D:
undetectable
2x2iB-2zt9D:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5

(Nostoc
sp.
PCC
7120)
4 / 5 ASN A  31
ALA G  24
GLY G  20
TYR G  23
None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
1.00A 3bcrA-2zt9A:
undetectable
3bcrA-2zt9A:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5

(Nostoc
sp.
PCC
7120)
4 / 6 ASN A  31
ALA G  24
GLY G  20
TYR G  23
None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
1.02A 3dd1A-2zt9A:
undetectable
3dd1A-2zt9A:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5

(Nostoc
sp.
PCC
7120)
4 / 6 ASN A  31
ALA G  24
GLY G  20
TYR G  23
None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
1.03A 3dd1B-2zt9A:
undetectable
3dd1B-2zt9A:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5

(Nostoc
sp.
PCC
7120)
4 / 6 ASN A  31
ALA G  24
GLY G  20
TYR G  23
None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
1.03A 3ddsA-2zt9A:
undetectable
3ddsA-2zt9A:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5

(Nostoc
sp.
PCC
7120)
4 / 6 ASN A  31
ALA G  24
GLY G  20
TYR G  23
None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
1.03A 3ddsB-2zt9A:
undetectable
3ddsB-2zt9A:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5

(Nostoc
sp.
PCC
7120)
4 / 6 ASN A  31
ALA G  24
GLY G  20
TYR G  23
None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
1.02A 3ddwA-2zt9A:
undetectable
3ddwA-2zt9A:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5

(Nostoc
sp.
PCC
7120)
4 / 6 ASN A  31
ALA G  24
GLY G  20
TYR G  23
None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
1.01A 3ddwB-2zt9A:
undetectable
3ddwB-2zt9A:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 4
CYTOCHROME B6-F
COMPLEX SUBUNIT 8

(Nostoc
sp.
PCC
7120;
Nostoc
sp.
PCC
7120;
Nostoc
sp.
PCC
7120)
5 / 10 ILE B  44
VAL A  42
GLY A  38
VAL H  22
LEU B  36
None
None
HEM  A 303 ( 3.4A)
None
None
1.10A 3elzC-2zt9B:
undetectable
3elzC-2zt9B:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 4
CYTOCHROME B6-F
COMPLEX SUBUNIT 8

(Nostoc
sp.
PCC
7120;
Nostoc
sp.
PCC
7120;
Nostoc
sp.
PCC
7120)
5 / 10 ILE B  44
VAL A  42
GLY A  38
VAL H  22
LEU B  36
None
None
HEM  A 303 ( 3.4A)
None
None
1.11A 3em0A-2zt9B:
undetectable
3em0A-2zt9B:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 4
CYTOCHROME B6-F
COMPLEX SUBUNIT 5

(Nostoc
sp.
PCC
7120;
Nostoc
sp.
PCC
7120;
Nostoc
sp.
PCC
7120)
5 / 9 MET A  96
LEU G  13
SER A  89
VAL B  43
GLY B  46
OPC  H  30 ( 3.9A)
BCR  G 101 ( 4.0A)
None
BCR  G 101 ( 3.9A)
BCR  G 101 ( 4.7A)
1.41A 3hcoA-2zt9A:
undetectable
3hcoA-2zt9A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 4
CYTOCHROME B6-F
COMPLEX SUBUNIT 5

(Nostoc
sp.
PCC
7120;
Nostoc
sp.
PCC
7120;
Nostoc
sp.
PCC
7120)
5 / 10 MET A  96
LEU G  13
SER A  89
VAL B  43
GLY B  46
OPC  H  30 ( 3.9A)
BCR  G 101 ( 4.0A)
None
BCR  G 101 ( 3.9A)
BCR  G 101 ( 4.7A)
1.42A 3hcoB-2zt9A:
undetectable
3hcoB-2zt9A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)
2zt9 CYTOCHROME B6-F
COMPLEX SUBUNIT 4
CYTOCHROME B6-F
COMPLEX SUBUNIT 5

(Nostoc
sp.
PCC
7120;
Nostoc
sp.
PCC
7120)
3 / 3 GLY B  23
PRO B   7
LEU G  35
None
0.61A 3hcpB-2zt9B:
undetectable
3hcpB-2zt9B:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA500_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)
2zt9 CYTOCHROME B6-F
COMPLEX IRON-SULFUR
SUBUNIT 1

(Nostoc
sp.
PCC
7120)
4 / 4 ALA D 144
HIS D 110
HIS D 129
PRO D 143
FES  D 200 ( 4.8A)
FES  D 200 (-3.2A)
FES  D 200 (-3.0A)
FES  D 200 ( 4.5A)
1.25A 3mbgA-2zt9D:
undetectable
3mbgA-2zt9D:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC900_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)
2zt9 CYTOCHROME B6-F
COMPLEX IRON-SULFUR
SUBUNIT 1

(Nostoc
sp.
PCC
7120)
4 / 4 ALA D 144
HIS D 110
HIS D 129
PRO D 143
FES  D 200 ( 4.8A)
FES  D 200 (-3.2A)
FES  D 200 (-3.0A)
FES  D 200 ( 4.5A)
1.25A 3mbgC-2zt9D:
undetectable
3mbgC-2zt9D:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_A_AICA375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)
2zt9 CYTOCHROME B6-F
COMPLEX SUBUNIT 5
CYTOCHROME B6-F
COMPLEX SUBUNIT 7

(Nostoc
sp.
PCC
7120)
5 / 11 GLY G   8
LEU F  10
SER F  12
LEU F   6
LEU F   5
None
None
OPC  H  30 (-4.8A)
None
None
1.18A 3ndvA-2zt9G:
undetectable
3ndvB-2zt9G:
undetectable
3ndvA-2zt9G:
9.84
3ndvB-2zt9G:
9.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_B_AICB376_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)
2zt9 CYTOCHROME B6-F
COMPLEX SUBUNIT 5
CYTOCHROME B6-F
COMPLEX SUBUNIT 7

(Nostoc
sp.
PCC
7120)
5 / 11 LEU F   6
LEU F   5
GLY G   8
LEU F  10
SER F  12
None
None
None
None
OPC  H  30 (-4.8A)
1.15A 3ndvA-2zt9F:
undetectable
3ndvB-2zt9F:
undetectable
3ndvA-2zt9F:
7.78
3ndvB-2zt9F:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_C_AICC375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)
2zt9 CYTOCHROME B6-F
COMPLEX SUBUNIT 5
CYTOCHROME B6-F
COMPLEX SUBUNIT 7

(Nostoc
sp.
PCC
7120)
5 / 11 GLY G   8
LEU F  10
SER F  12
LEU F   6
LEU F   5
None
None
OPC  H  30 (-4.8A)
None
None
1.15A 3ndvC-2zt9G:
undetectable
3ndvD-2zt9G:
undetectable
3ndvC-2zt9G:
9.84
3ndvD-2zt9G:
9.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_D_AICD374_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)
2zt9 CYTOCHROME B6-F
COMPLEX SUBUNIT 5
CYTOCHROME B6-F
COMPLEX SUBUNIT 7

(Nostoc
sp.
PCC
7120)
5 / 11 LEU F   6
LEU F   5
GLY G   8
LEU F  10
SER F  12
None
None
None
None
OPC  H  30 (-4.8A)
1.16A 3ndvC-2zt9F:
undetectable
3ndvD-2zt9F:
undetectable
3ndvC-2zt9F:
7.78
3ndvD-2zt9F:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 4

(Nostoc
sp.
PCC
7120)
4 / 7 ARG A  87
TYR B  80
LEU B  81
TYR A 183
HEM  A 301 (-3.6A)
None
None
None
1.13A 4f8yC-2zt9A:
undetectable
4f8yD-2zt9A:
undetectable
4f8yC-2zt9A:
22.62
4f8yD-2zt9A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_A_8PRA601_1
(RHODOPSIN KINASE)
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 4

(Nostoc
sp.
PCC
7120)
4 / 7 VAL A 151
ALA A 147
LEU A 169
LEU B  81
None
0.82A 4l9iA-2zt9A:
2.5
4l9iA-2zt9A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_B_ACTB202_0
(RETINOL-BINDING
PROTEIN 2)
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 4

(Nostoc
sp.
PCC
7120;
Nostoc
sp.
PCC
7120)
4 / 7 TYR A 136
TYR B  82
LEU B  76
TRP B  79
None
1.40A 4qzuB-2zt9A:
0.0
4qzuB-2zt9A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)
2zt9 CYTOCHROME B6-F
COMPLEX IRON-SULFUR
SUBUNIT 1
CYTOCHROME B6-F
COMPLEX SUBUNIT 4

(Nostoc
sp.
PCC
7120)
4 / 8 LEU D  32
GLY D  33
MET B  45
ALA B  49
None
0.90A 4rjdA-2zt9D:
undetectable
4rjdB-2zt9D:
undetectable
4rjdA-2zt9D:
18.06
4rjdB-2zt9D:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_G_377G401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
2zt9 CYTOCHROME B6-F
COMPLEX SUBUNIT 4

(Nostoc
sp.
PCC
7120)
4 / 6 TYR B  82
ARG B  89
GLU B  74
LEU B 149
None
1.15A 4twdF-2zt9B:
undetectable
4twdG-2zt9B:
undetectable
4twdF-2zt9B:
19.22
4twdG-2zt9B:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)
2zt9 CYTOCHROME B6
(Nostoc
sp.
PCC
7120)
4 / 4 ALA A 125
VAL A 101
GLY A  37
THR A  40
HEM  A 302 ( 3.8A)
HEM  A 302 (-4.1A)
HEM  A 302 (-3.3A)
HEM  A 302 (-4.2A)
1.10A 4ubeA-2zt9A:
undetectable
4ubeA-2zt9A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)
2zt9 CYTOCHROME B6-F
COMPLEX SUBUNIT 4

(Nostoc
sp.
PCC
7120)
4 / 7 SER B  90
LEU B 155
ILE B 145
LEU B 157
None
0.88A 5te8A-2zt9B:
undetectable
5te8A-2zt9B:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA605_0
(ALPHA-AMYLASE)
2zt9 CYTOCHROME B6-F
COMPLEX SUBUNIT 4
CYTOCHROME B6-F
COMPLEX SUBUNIT 8

(Nostoc
sp.
PCC
7120;
Nostoc
sp.
PCC
7120)
4 / 8 TYR B  38
GLY H  25
ASP B  35
PRO B  30
None
None
HEM  A 303 ( 4.6A)
None
0.78A 6ag0A-2zt9B:
undetectable
6ag0A-2zt9B:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC605_0
(ALPHA-AMYLASE)
2zt9 CYTOCHROME B6-F
COMPLEX SUBUNIT 4
CYTOCHROME B6-F
COMPLEX SUBUNIT 8

(Nostoc
sp.
PCC
7120;
Nostoc
sp.
PCC
7120)
4 / 8 TYR B  38
GLY H  25
ASP B  35
PRO B  30
None
None
HEM  A 303 ( 4.6A)
None
0.82A 6ag0C-2zt9B:
undetectable
6ag0C-2zt9B:
23.12