SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ztb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 2ztb CRYSTAL PROTEIN
(Bacillus
thuringiensis) 		5 / 12 THR A 192
THR A 193
LEU A 276
VAL A 118
ILE A  54
 None
 1.24A 3sp9A-2ztbA:
undetectable		 3sp9A-2ztbA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 2ztb CRYSTAL PROTEIN
(Bacillus
thuringiensis) 		4 / 4 VAL A  73
LEU A  66
ASN A 263
ASP A 267
 None
 1.27A 5vcyA-2ztbA:
undetectable		 5vcyA-2ztbA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EFN_A_SAMA501_0
(SPORULATION KILLING
FACTOR MATURATION
PROTEIN SKFB)		 2ztb CRYSTAL PROTEIN
(Bacillus
thuringiensis) 		5 / 11 PHE A 182
SER A 232
ALA A 233
THR A 279
THR A 163
 None
 1.41A 6efnA-2ztbA:
undetectable		 6efnA-2ztbA:
20.24