SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ztg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		4 / 8 ARG A  76
TYR A 161
GLU A 172
TYR A  68
 None
 1.25A 1nx9A-2ztgA:
undetectable		 1nx9A-2ztgA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		4 / 8 ARG A  76
TYR A 161
GLU A 172
TYR A  68
 None
 1.25A 1nx9B-2ztgA:
undetectable		 1nx9B-2ztgA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		4 / 8 ARG A  76
TYR A 161
GLU A 172
TYR A  68
 None
 1.25A 1nx9C-2ztgA:
undetectable		 1nx9C-2ztgA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		4 / 8 ARG A  76
TYR A 161
GLU A 172
TYR A  68
 None
 1.25A 1nx9D-2ztgA:
undetectable		 1nx9D-2ztgA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_1
(TRANSTHYRETIN)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		4 / 6 LEU A 213
ALA A 203
LEU A 201
VAL A 205
 None
 1.11A 1sn5A-2ztgA:
undetectable		 1sn5A-2ztgA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_1
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		3 / 3 ARG A 418
ARG A 367
ILE A 411
 None
 0.82A 1uobA-2ztgA:
undetectable		 1uobA-2ztgA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMA_A_SAMA375_0
(PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		5 / 11 GLY A 299
THR A 138
GLY A 139
HIS A 141
PHE A 145
 None
None
None
A5A  A 801 (-4.7A)
A5A  A 801 (-3.5A)
 1.43A 2hmaA-2ztgA:
undetectable		 2hmaA-2ztgA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		5 / 12 ASN A 545
VAL A 562
LEU A 515
SER A 534
ASP A 591
 None
 1.31A 2iyfB-2ztgA:
undetectable		 2iyfB-2ztgA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_2
(ESTROGEN RECEPTOR)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		4 / 4 LEU A 144
THR A 143
ILE A 396
HIS A 393
 None
 1.41A 2jfaB-2ztgA:
undetectable		 2jfaB-2ztgA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_2
(THYMIDYLATE SYNTHASE)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		3 / 3 HIS A 151
ILE A  81
LEU A  70
 None
 0.70A 2kceA-2ztgA:
undetectable		 2kceA-2ztgA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGZ_D_COCD401_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		4 / 6 TRP A 252
TYR A 338
TYR A  48
ILE A  51
 None
 0.81A 2pgzD-2ztgA:
undetectable
2pgzE-2ztgA:
undetectable		 2pgzD-2ztgA:
14.01
2pgzE-2ztgA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		4 / 7 TRP A 252
TYR A 338
TYR A  48
ILE A  51
 None
 0.70A 2ph9A-2ztgA:
undetectable
2ph9B-2ztgA:
undetectable		 2ph9A-2ztgA:
14.01
2ph9B-2ztgA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_0
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		5 / 12 ALA A 621
GLY A 363
GLY A 728
ALA A 362
LEU A  96
 None
 1.11A 2plwA-2ztgA:
undetectable		 2plwA-2ztgA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_A_SAMA500_0
(HYPOTHETICAL PROTEIN)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		4 / 7 ASP A 270
VAL A 269
ALA A 341
THR A 257
 None
 1.02A 2q6oA-2ztgA:
3.4		 2q6oA-2ztgA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		4 / 8 VAL A 260
THR A 138
VAL A 135
SER A 134
 None
 0.84A 2v32C-2ztgA:
undetectable
2v32D-2ztgA:
undetectable		 2v32C-2ztgA:
15.36
2v32D-2ztgA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_B_CTCB1385_0
(TETX2 PROTEIN)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		4 / 8 GLN A 105
ARG A 128
GLY A 194
GLY A 244
 None
A5A  A 801 (-2.7A)
None
A5A  A 801 (-4.0A)
 0.82A 2y6rB-2ztgA:
undetectable		 2y6rB-2ztgA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		3 / 3 LEU A  13
TRP A 162
TYR A   7
 None
 0.94A 3aicA-2ztgA:
undetectable		 3aicA-2ztgA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		3 / 3 LEU A  13
TRP A 162
TYR A   7
 None
 0.95A 3aicB-2ztgA:
undetectable		 3aicB-2ztgA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		3 / 3 LEU A  13
TRP A 162
TYR A   7
 None
 0.96A 3aicE-2ztgA:
undetectable		 3aicE-2ztgA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		3 / 3 LEU A  13
TRP A 162
TYR A   7
 None
 0.97A 3aicF-2ztgA:
undetectable		 3aicF-2ztgA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_2
(GLUCOSYLTRANSFERASE-
SI)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		3 / 3 LEU A  13
TRP A 162
TYR A   7
 None
 0.92A 3aicG-2ztgA:
undetectable		 3aicG-2ztgA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		3 / 3 LEU A  13
TRP A 162
TYR A   7
 None
 0.94A 3aicH-2ztgA:
undetectable		 3aicH-2ztgA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FGR_B_ACTB21_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		4 / 4 ARG A  83
ASP A 402
ASP A 353
PRO A  85
 None
 1.41A 3fgrB-2ztgA:
undetectable		 3fgrB-2ztgA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		4 / 8 GLY A 206
ASP A 183
ILE A 184
VAL A 210
 None
None
None
A5A  A 801 (-4.8A)
 0.73A 3fi0G-2ztgA:
undetectable		 3fi0G-2ztgA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_I_TRPI1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		4 / 8 GLY A 206
ASP A 183
ILE A 184
VAL A 210
 None
None
None
A5A  A 801 (-4.8A)
 0.74A 3fi0I-2ztgA:
undetectable		 3fi0I-2ztgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_Q_TRPQ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		4 / 8 GLY A 206
ASP A 183
ILE A 184
VAL A 210
 None
None
None
A5A  A 801 (-4.8A)
 0.76A 3fi0Q-2ztgA:
undetectable		 3fi0Q-2ztgA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVC_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		4 / 6 HIS A 600
HIS A 604
ARG A 692
HIS A 707
 ZN  A 902 (-3.2A)
ZN  A 902 (-3.4A)
None
ZN  A 902 (-3.1A)
 0.90A 3nvcA-2ztgA:
undetectable		 3nvcA-2ztgA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		4 / 8 GLN A 105
ARG A 128
GLY A 194
GLY A 244
 None
A5A  A 801 (-2.7A)
None
A5A  A 801 (-4.0A)
 0.65A 3v3nB-2ztgA:
undetectable		 3v3nB-2ztgA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		4 / 8 GLN A 105
ARG A 128
GLY A 194
GLY A 244
 None
A5A  A 801 (-2.7A)
None
A5A  A 801 (-4.0A)
 0.65A 3v3nC-2ztgA:
undetectable		 3v3nC-2ztgA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ARC_A_LEUA1001_0
(LEUCINE--TRNA LIGASE)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		4 / 7 LEU A 213
TYR A 161
HIS A 151
HIS A 150
 None
 1.30A 4arcA-2ztgA:
1.9		 4arcA-2ztgA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_C_NCTC501_1
(CYTOCHROME P450 2A13)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		4 / 7 PHE A  72
PHE A  73
ALA A 168
LEU A 213
 None
 0.91A 4ejgC-2ztgA:
undetectable		 4ejgC-2ztgA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA504_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		4 / 8 PHE A 536
GLY A 586
LEU A 550
ILE A 551
 None
 0.86A 4em2A-2ztgA:
undetectable		 4em2A-2ztgA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		4 / 8 ARG A 128
PHE A 145
THR A 212
ARG A 249
 A5A  A 801 (-2.7A)
A5A  A 801 (-3.5A)
A5A  A 801 (-3.4A)
A5A  A 801 (-4.0A)
 0.53A 4k87A-2ztgA:
8.0		 4k87A-2ztgA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_B_ACTB401_0
(3C-LIKE PROTEINASE)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		3 / 3 ARG A 593
ASP A 546
TYR A 508
 None
 0.87A 4yo9B-2ztgA:
undetectable		 4yo9B-2ztgA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		4 / 6 LEU A 213
ALA A 203
LEU A 201
VAL A 205
 None
 1.28A 5a6iA-2ztgA:
undetectable		 5a6iA-2ztgA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		6 / 11 GLY A 244
LEU A 174
VAL A 167
THR A 212
GLU A 202
ALA A 203
 A5A  A 801 (-4.0A)
None
None
A5A  A 801 (-3.4A)
None
None
 1.48A 5o96G-2ztgA:
undetectable		 5o96G-2ztgA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_H_SAMH501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		5 / 10 LEU A 717
GLY A 715
GLY A 712
LEU A 606
ALA A 602
 None
 1.06A 5o96G-2ztgA:
undetectable
5o96H-2ztgA:
undetectable		 5o96G-2ztgA:
15.06
5o96H-2ztgA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		4 / 5 HIS A 636
HIS A 617
VAL A 356
THR A 407
 None
 1.35A 5ohhA-2ztgA:
undetectable		 5ohhA-2ztgA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA613_1
(SERUM ALBUMIN)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		4 / 8 ARG A 345
SER A 100
THR A  97
GLY A 246
 None
None
None
A5A  A 801 (-3.3A)
 1.00A 5v0vA-2ztgA:
3.3		 5v0vA-2ztgA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		3 / 3 ARG A  83
PHE A 250
LEU A  62
 None
 0.84A 5veuA-2ztgA:
undetectable		 5veuA-2ztgA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		5 / 12 ALA A 341
SER A 339
LEU A 142
VAL A 135
ASP A 262
 None
None
A5A  A 801 (-4.2A)
None
None
 1.14A 5w7pA-2ztgA:
undetectable		 5w7pA-2ztgA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_K_PACK1_0
(SERINE PROTEASE NS3
PEPTIDE
PAC-DLY-DLY-DAR)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		3 / 3 ALA A 481
VAL A 456
TYR A 449
 None
 0.60A 5zmqH-2ztgA:
undetectable		 5zmqH-2ztgA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AJI_A_AY6A1001_0
(DRUG EXPORTERS OF
THE RND
SUPERFAMILY-LIKE
PROTEIN,ENDOLYSIN)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		5 / 12 ILE A  98
LEU A 129
PHE A 145
ALA A 362
LEU A 365
 None
None
A5A  A 801 (-3.5A)
None
None
 1.09A 6ajiA-2ztgA:
undetectable		 6ajiA-2ztgA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_A_ADNA602_1
(LYSINE--TRNA LIGASE)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		6 / 10 ARG A 128
HIS A 141
PHE A 145
GLU A 209
GLY A 246
ARG A 249
 A5A  A 801 (-2.7A)
A5A  A 801 (-4.7A)
A5A  A 801 (-3.5A)
A5A  A 801 (-3.7A)
A5A  A 801 (-3.3A)
A5A  A 801 (-4.0A)
 0.71A 6bniA-2ztgA:
10.8		 6bniA-2ztgA:
7.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_B_ADNB602_1
(LYSINE--TRNA LIGASE)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		6 / 10 ARG A 128
HIS A 141
PHE A 145
GLU A 209
GLY A 246
ARG A 249
 A5A  A 801 (-2.7A)
A5A  A 801 (-4.7A)
A5A  A 801 (-3.5A)
A5A  A 801 (-3.7A)
A5A  A 801 (-3.3A)
A5A  A 801 (-4.0A)
 0.68A 6bniB-2ztgA:
10.7		 6bniB-2ztgA:
7.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB503_0
(AMINE OXIDASE LKCE)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		3 / 3 VAL A 568
GLU A 564
ILE A 530
 None
 0.46A 6f7lB-2ztgA:
undetectable		 6f7lB-2ztgA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 2ztg ALANYL-TRNA
SYNTHETASE
(Archaeoglobus
fulgidus) 		3 / 3 VAL A 729
ALA A 621
GLN A 726
 None
 0.62A 6gb9A-2ztgA:
undetectable		 6gb9A-2ztgA:
20.89