SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zu6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_A_ADNA601_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
PROGRAMMED CELL
DEATH PROTEIN 4
(Homo
sapiens) 		4 / 5 THR B 169
GLU A 111
THR A 109
HIS B 215
 None
 1.34A 1d4fA-2zu6B:
undetectable		 1d4fA-2zu6B:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
PROGRAMMED CELL
DEATH PROTEIN 4
(Homo
sapiens) 		4 / 5 THR B 169
GLU A 111
THR A 109
HIS B 215
 None
 1.33A 1d4fB-2zu6B:
undetectable		 1d4fB-2zu6B:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
PROGRAMMED CELL
DEATH PROTEIN 4
(Homo
sapiens) 		4 / 5 THR B 169
GLU A 111
THR A 109
HIS B 215
 None
 1.30A 1d4fD-2zu6B:
undetectable		 1d4fD-2zu6B:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)		 2zu6 PROGRAMMED CELL
DEATH PROTEIN 4
(Homo
sapiens) 		4 / 7 PHE B 240
ALA B 268
PHE B 264
SER B 220
 None
 1.14A 1lqtA-2zu6B:
undetectable		 1lqtA-2zu6B:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)		 2zu6 PROGRAMMED CELL
DEATH PROTEIN 4
(Homo
sapiens) 		4 / 7 PHE B 240
ALA B 268
PHE B 264
SER B 220
 None
 1.16A 1lquA-2zu6B:
undetectable		 1lquA-2zu6B:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_0
(AMINOMETHYLTRANSFERA
SE)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
(Homo
sapiens) 		5 / 12 LEU A 263
ILE A 345
VAL A 344
MET A 375
LEU A 288
 None
 1.20A 1wsvA-2zu6A:
undetectable		 1wsvA-2zu6A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
(Homo
sapiens) 		5 / 12 LEU A 263
ILE A 345
VAL A 344
MET A 375
LEU A 288
 None
 1.18A 1wsvB-2zu6A:
undetectable		 1wsvB-2zu6A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_A_J01A1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
(Homo
sapiens) 		5 / 12 LEU A 212
SER A  89
VAL A 236
ALA A  74
THR A  83
 EDO  A   3 ( 4.5A)
ACY  A   1 (-3.6A)
None
None
None
 1.26A 2japA-2zu6A:
2.8		 2japA-2zu6A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_D_J01D1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
(Homo
sapiens) 		5 / 12 LEU A 212
SER A  89
VAL A 236
ALA A  74
THR A  83
 EDO  A   3 ( 4.5A)
ACY  A   1 (-3.6A)
None
None
None
 1.27A 2japD-2zu6A:
2.1		 2japD-2zu6A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
(Homo
sapiens) 		4 / 7 ARG A 362
ILE A 360
ASN A 346
PHE A 278
 None
 1.23A 2jc9A-2zu6A:
undetectable		 2jc9A-2zu6A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 2zu6 PROGRAMMED CELL
DEATH PROTEIN 4
(Homo
sapiens) 		5 / 9 GLY B 270
LEU B 274
TYR B 278
ALA B 266
LEU B 301
 None
 0.89A 2npnA-2zu6B:
undetectable		 2npnA-2zu6B:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_GLYA333_0
(CHOLOYLGLYCINE
HYDROLASE)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
(Homo
sapiens) 		3 / 3 ASN A 352
ASN A 355
ARG A 334
 None
 0.70A 2rlcA-2zu6A:
undetectable		 2rlcA-2zu6A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRH_A_NIOA200_1
(PROTEIN HP0721)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
(Homo
sapiens) 		4 / 7 GLY A 370
ILE A 360
ARG A 362
LEU A 343
 None
 0.97A 2xrhA-2zu6A:
undetectable		 2xrhA-2zu6A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CO4_A_GCSA401_1
(CHITINASE)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
PROGRAMMED CELL
DEATH PROTEIN 4
(Homo
sapiens) 		3 / 3 GLU A 240
HIS B 361
HIS B 360
 None
 0.86A 3co4A-2zu6A:
undetectable		 3co4A-2zu6A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
PROGRAMMED CELL
DEATH PROTEIN 4
(Homo
sapiens) 		5 / 12 ASP A 219
LEU B 390
SER B 393
GLU B 348
LEU B 351
 None
 1.25A 3ko0G-2zu6A:
undetectable
3ko0H-2zu6A:
undetectable
3ko0I-2zu6A:
undetectable
3ko0J-2zu6A:
undetectable		 3ko0G-2zu6A:
13.40
3ko0H-2zu6A:
13.40
3ko0I-2zu6A:
13.40
3ko0J-2zu6A:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RNJ_A_EDTA1_0
(BRAIN-SPECIFIC
ANGIOGENESIS
INHIBITOR
1-ASSOCIATED PROTEIN
2)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
(Homo
sapiens) 		4 / 4 LYS A 291
ARG A 295
LEU A 260
ASP A 261
 None
 1.25A 3rnjA-2zu6A:
0.0		 3rnjA-2zu6A:
9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
PROGRAMMED CELL
DEATH PROTEIN 4
(Homo
sapiens) 		3 / 3 TYR B 409
LEU A 243
ARG B 407
 None
 0.76A 3sufB-2zu6B:
undetectable		 3sufB-2zu6B:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
(Homo
sapiens) 		4 / 8 LEU A 263
LEU A 266
ILE A 272
MET A 292
 None
 0.93A 4oj4A-2zu6A:
undetectable		 4oj4A-2zu6A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA601_1
(SERUM ALBUMIN)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
(Homo
sapiens) 		5 / 12 VAL A 344
LEU A 243
TYR A 391
VAL A 338
ARG A 359
 None
 1.44A 4po0A-2zu6A:
undetectable		 4po0A-2zu6A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
(Homo
sapiens) 		3 / 3 GLY A 160
PRO A 159
ALA A 107
 None
 0.49A 4qn9B-2zu6A:
undetectable		 4qn9B-2zu6A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
(Homo
sapiens) 		4 / 8 LEU A 263
LEU A 266
ILE A 272
MET A 292
 None
 0.93A 4xtaB-2zu6A:
undetectable		 4xtaB-2zu6A:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2zu6 PROGRAMMED CELL
DEATH PROTEIN 4
(Homo
sapiens) 		4 / 5 GLU B 165
THR B 169
THR B 219
LEU B 209
 None
 1.31A 5axaA-2zu6B:
undetectable		 5axaA-2zu6B:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
(Homo
sapiens) 		3 / 3 THR A 207
HIS A 132
LEU A 171
 None
 0.85A 5axdC-2zu6A:
undetectable		 5axdC-2zu6A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNU_A_BEZA319_0
(SHKAI2IB)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
(Homo
sapiens) 		4 / 5 GLN A 248
ILE A 360
ILE A 373
TYR A 356
 None
 1.27A 5dnuA-2zu6A:
undetectable		 5dnuA-2zu6A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
(Homo
sapiens) 		4 / 8 ILE A 116
ALA A 103
VAL A 180
VAL A 120
 None
 0.60A 5ecnD-2zu6A:
2.3		 5ecnD-2zu6A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 2zu6 PROGRAMMED CELL
DEATH PROTEIN 4
(Homo
sapiens) 		5 / 11 PHE B 380
ILE B 368
TYR B 405
ILE B 439
ILE B 438
 None
 1.14A 5hw8E-2zu6B:
undetectable		 5hw8E-2zu6B:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 2zu6 PROGRAMMED CELL
DEATH PROTEIN 4
(Homo
sapiens) 		5 / 12 PHE B 380
ILE B 368
TYR B 405
ILE B 439
ILE B 438
 None
 1.10A 5hw8B-2zu6B:
undetectable
5hw8F-2zu6B:
undetectable
5hw8G-2zu6B:
undetectable		 5hw8B-2zu6B:
18.94
5hw8F-2zu6B:
18.94
5hw8G-2zu6B:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IM2_A_BEZA401_0
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
(Homo
sapiens) 		5 / 12 PHE A 179
PRO A 173
LEU A 104
LEU A 171
VAL A 162
 None
 1.08A 5im2A-2zu6A:
1.8		 5im2A-2zu6A:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 2zu6 PROGRAMMED CELL
DEATH PROTEIN 4
(Homo
sapiens) 		3 / 3 LYS B 311
ASP B 312
ARG B 267
 None
 1.05A 5jwaA-2zu6B:
undetectable
5jwaH-2zu6B:
undetectable		 5jwaA-2zu6B:
20.12
5jwaH-2zu6B:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
(Homo
sapiens) 		3 / 3 THR A 215
PRO A 217
ASP A 219
 None
 0.79A 5l8dB-2zu6A:
undetectable		 5l8dB-2zu6A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0I_B_ACTB303_0
(SWI5-DEPENDENT HO
EXPRESSION PROTEIN 2)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
(Homo
sapiens) 		4 / 5 THR A 351
ASN A 280
ASP A 348
LEU A 349
 None
 1.26A 5m0iB-2zu6A:
undetectable		 5m0iB-2zu6A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
(Homo
sapiens) 		4 / 5 ARG A 334
THR A 329
ALA A 333
ASP A 330
 None
 1.44A 5mfxA-2zu6A:
9.7		 5mfxA-2zu6A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
(Homo
sapiens) 		3 / 3 THR A 215
PRO A 217
ASP A 219
 None
 0.79A 5mwuB-2zu6A:
undetectable		 5mwuB-2zu6A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I
PROGRAMMED CELL
DEATH PROTEIN 4
(Homo
sapiens) 		3 / 3 GLY A  79
THR B 254
PRO A 108
 None
 0.54A 5v5zA-2zu6A:
undetectable		 5v5zA-2zu6A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_A_ADNA502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 2zu6 PROGRAMMED CELL
DEATH PROTEIN 4
(Homo
sapiens) 		4 / 4 GLU B 165
THR B 169
THR B 219
LEU B 209
 None
 1.31A 5v96A-2zu6B:
undetectable		 5v96A-2zu6B:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 2zu6 PROGRAMMED CELL
DEATH PROTEIN 4
(Homo
sapiens) 		4 / 4 GLU B 165
THR B 169
THR B 219
LEU B 209
 None
 1.31A 5v96B-2zu6B:
undetectable		 5v96B-2zu6B:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 2zu6 PROGRAMMED CELL
DEATH PROTEIN 4
(Homo
sapiens) 		4 / 4 GLU B 165
THR B 169
THR B 219
LEU B 209
 None
 1.33A 5v96C-2zu6B:
undetectable		 5v96C-2zu6B:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 2zu6 PROGRAMMED CELL
DEATH PROTEIN 4
(Homo
sapiens) 		4 / 4 GLU B 165
THR B 169
THR B 219
LEU B 209
 None
 1.33A 5v96D-2zu6B:
undetectable		 5v96D-2zu6B:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2zu6 PROGRAMMED CELL
DEATH PROTEIN 4
(Homo
sapiens) 		4 / 6 GLN B 263
PHE B 264
PHE B 240
LEU B 274
 None
 1.11A 5z84P-2zu6B:
undetectable
5z84W-2zu6B:
undetectable		 5z84P-2zu6B:
22.29
5z84W-2zu6B:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2zu6 PROGRAMMED CELL
DEATH PROTEIN 4
(Homo
sapiens) 		4 / 6 GLN B 263
PHE B 264
PHE B 240
LEU B 274
 None
 1.09A 5z86C-2zu6B:
undetectable
5z86J-2zu6B:
undetectable		 5z86C-2zu6B:
22.29
5z86J-2zu6B:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2zu6 PROGRAMMED CELL
DEATH PROTEIN 4
(Homo
sapiens) 		4 / 6 GLN B 263
PHE B 264
PHE B 240
LEU B 274
 None
 1.10A 5zcpC-2zu6B:
undetectable
5zcpJ-2zu6B:
undetectable		 5zcpC-2zu6B:
22.29
5zcpJ-2zu6B:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2zu6 PROGRAMMED CELL
DEATH PROTEIN 4
(Homo
sapiens) 		4 / 6 GLN B 263
PHE B 264
PHE B 240
LEU B 274
 None
 1.09A 5zcpP-2zu6B:
undetectable
5zcpW-2zu6B:
undetectable		 5zcpP-2zu6B:
22.29
5zcpW-2zu6B:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 2zu6 PROGRAMMED CELL
DEATH PROTEIN 4
(Homo
sapiens) 		5 / 12 ILE B 396
TYR B 405
LEU B 351
ALA B 367
LEU B 335
 None
 1.39A 5zwrB-2zu6B:
undetectable		 5zwrB-2zu6B:
23.28