SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zup'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JAP_A_J01A1249_1 (CLAVALDEHYDE DEHYDROGENASE)	2zup	DISULFIDE BOND FORMATION PROTEIN B (Escherichia coli)	5 / 12	ILE B 63 ALA B 14 VAL B 161 ALA B 157 LEU B 55	None	1.14A	2japA-2zupB: undetectable	2japA-2zupB: 24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JAP_B_J01B1249_1 (CLAVALDEHYDE DEHYDROGENASE)	2zup	DISULFIDE BOND FORMATION PROTEIN B (Escherichia coli)	5 / 12	ILE B 63 ALA B 14 VAL B 161 ALA B 157 LEU B 55	None	1.18A	2japB-2zupB: undetectable	2japB-2zupB: 24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JAP_C_J01C1249_1 (CLAVALDEHYDE DEHYDROGENASE)	2zup	DISULFIDE BOND FORMATION PROTEIN B (Escherichia coli)	5 / 12	ILE B 63 ALA B 14 VAL B 161 ALA B 157 LEU B 55	None	1.13A	2japC-2zupB: undetectable	2japC-2zupB: 24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JAP_D_J01D1249_1 (CLAVALDEHYDE DEHYDROGENASE)	2zup	DISULFIDE BOND FORMATION PROTEIN B (Escherichia coli)	5 / 12	ILE B 63 ALA B 14 VAL B 161 ALA B 157 LEU B 55	None	1.16A	2japD-2zupB: undetectable	2japD-2zupB: 24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KSZ_A_CYSA620_0 (LACTOPEROXIDASE)	2zup	DISULFIDE BOND FORMATION PROTEIN B (Escherichia coli)	3 / 3	ARG B 48 GLU B 47 PHE B 150	UQ1 B 177 (-4.5A) UQ1 B 177 (-3.5A) None	0.87A	4kszA-2zupB: undetectable	4kszA-2zupB: 14.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2JAP_A_J01A1249_1","CLAVALDEHYDE DEHYDROGENASE","2zup","DISULFIDE BOND FORMATION PROTEIN B","Escherichia coli",5,"ILE B  63;ALA B  14;VAL B 161;ALA B 157;LEU B  55","None","1.14A","2japA-2zupB:undetectable","2japA-2zupB:24.59"],["2JAP_B_J01B1249_1","CLAVALDEHYDE DEHYDROGENASE","2zup","DISULFIDE BOND FORMATION PROTEIN B","Escherichia coli",5,"ILE B  63;ALA B  14;VAL B 161;ALA B 157;LEU B  55","None","1.18A","2japB-2zupB:undetectable","2japB-2zupB:24.59"],["2JAP_C_J01C1249_1","CLAVALDEHYDE DEHYDROGENASE","2zup","DISULFIDE BOND FORMATION PROTEIN B","Escherichia coli",5,"ILE B  63;ALA B  14;VAL B 161;ALA B 157;LEU B  55","None","1.13A","2japC-2zupB:undetectable","2japC-2zupB:24.59"],["2JAP_D_J01D1249_1","CLAVALDEHYDE DEHYDROGENASE","2zup","DISULFIDE BOND FORMATION PROTEIN B","Escherichia coli",5,"ILE B  63;ALA B  14;VAL B 161;ALA B 157;LEU B  55","None","1.16A","2japD-2zupB:undetectable","2japD-2zupB:24.59"],["4KSZ_A_CYSA620_0","LACTOPEROXIDASE","2zup","DISULFIDE BOND FORMATION PROTEIN B","Escherichia coli",3,"ARG B  48;GLU B  47;PHE B 150","UQ1 B 177 (-4.5A);UQ1 B 177 (-3.5A);None","0.87A","4kszA-2zupB:undetectable","4kszA-2zupB:14.00"]]