SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zux'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IIU_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		5 / 11 LEU A 312
LEU A 319
ALA A 232
MET A 219
TYR A 221
 None
 1.40A 1iiuA-2zuxA:
undetectable		 1iiuA-2zuxA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		5 / 12 HIS A 421
ALA A 402
VAL A 450
GLY A 451
ALA A 426
 None
 1.20A 1kxhA-2zuxA:
undetectable		 1kxhA-2zuxA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		5 / 10 GLY A 406
HIS A 600
VAL A 583
ALA A 435
ILE A 379
 None
 1.08A 1likA-2zuxA:
undetectable		 1likA-2zuxA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA732_1
(ALPHA AMYLASE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		5 / 9 GLY A 273
GLU A  43
GLY A 157
GLY A 227
ASP A 226
 None
None
None
None
CA  A 633 (-2.9A)
 1.17A 1mxdA-2zuxA:
undetectable		 1mxdA-2zuxA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_B_SAMB302_0
(RRNA
METHYLTRANSFERASE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		5 / 10 ASP A 369
GLU A 377
GLY A 314
ILE A 367
ALA A 310
 CA  A 638 (-3.1A)
CA  A 638 ( 2.0A)
None
None
None
 0.95A 1x7pA-2zuxA:
undetectable
1x7pB-2zuxA:
undetectable		 1x7pA-2zuxA:
20.61
1x7pB-2zuxA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		4 / 4 GLY A  98
SER A 102
VAL A  60
LEU A  83
 None
 1.26A 1yajB-2zuxA:
undetectable		 1yajB-2zuxA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		5 / 12 LEU A 195
LEU A 545
GLY A 163
ASP A 162
ALA A 229
 None
None
None
CA  A 634 (-2.9A)
None
 1.17A 2bm9B-2zuxA:
undetectable		 2bm9B-2zuxA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_A_NCAA1501_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		4 / 7 ALA A 594
ARG A 304
ASP A 401
TYR A 595
 None
None
CA  A 629 (-2.5A)
RAM  A 639 (-4.7A)
 1.07A 2e5dA-2zuxA:
undetectable
2e5dB-2zuxA:
undetectable		 2e5dA-2zuxA:
22.91
2e5dB-2zuxA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_B_NCAB1502_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		4 / 7 ASP A 401
TYR A 595
ALA A 594
ARG A 304
 CA  A 629 (-2.5A)
RAM  A 639 (-4.7A)
None
None
 1.07A 2e5dA-2zuxA:
undetectable
2e5dB-2zuxA:
undetectable		 2e5dA-2zuxA:
22.91
2e5dB-2zuxA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		5 / 10 THR A 537
ALA A 536
ALA A 530
VAL A 552
GLY A 492
 None
 0.90A 2f16K-2zuxA:
undetectable
2f16L-2zuxA:
undetectable		 2f16K-2zuxA:
16.64
2f16L-2zuxA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		5 / 10 THR A 537
ALA A 536
ALA A 530
VAL A 552
GLY A 492
 None
 0.91A 2f16Y-2zuxA:
undetectable
2f16Z-2zuxA:
undetectable		 2f16Y-2zuxA:
16.64
2f16Z-2zuxA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		3 / 3 ASP A 237
ASN A 208
THR A 216
 None
 0.74A 2pymB-2zuxA:
undetectable		 2pymB-2zuxA:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_1
(ADENOSYLHOMOCYSTEINA
SE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		5 / 12 GLU A 502
ASP A 498
LEU A 575
LEU A 605
GLY A 606
 CA  A 632 (-2.2A)
CA  A 632 (-3.3A)
None
None
None
 1.45A 2zj0B-2zuxA:
undetectable		 2zj0B-2zuxA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		5 / 12 GLU A 502
ASP A 498
LEU A 575
LEU A 605
GLY A 606
 CA  A 632 (-2.2A)
CA  A 632 (-3.3A)
None
None
None
 1.46A 2zj0C-2zuxA:
undetectable		 2zj0C-2zuxA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		4 / 8 HIS A 421
GLY A 400
ASN A 362
PHE A 418
 None
 1.36A 3ccfA-2zuxA:
undetectable		 3ccfA-2zuxA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		4 / 6 THR A 269
ILE A 203
LEU A 205
THR A 235
 None
 0.74A 3deuB-2zuxA:
undetectable		 3deuB-2zuxA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		5 / 10 ILE A 378
ILE A 379
VAL A 417
GLY A 406
LEU A 586
 None
 1.19A 3em0A-2zuxA:
1.5		 3em0A-2zuxA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_2
(ADENOSYLHOMOCYSTEINA
SE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		4 / 5 THR A  91
GLU A  68
THR A  67
HIS A 580
 None
 1.34A 3glqA-2zuxA:
undetectable		 3glqA-2zuxA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_2
(ADENOSYLHOMOCYSTEINA
SE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		4 / 5 THR A  91
GLU A  68
THR A  67
HIS A 580
 None
 1.38A 3glqB-2zuxA:
undetectable		 3glqB-2zuxA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		4 / 7 LEU A 500
ARG A 461
PRO A 486
GLY A 517
 None
 0.95A 3hcnA-2zuxA:
undetectable		 3hcnA-2zuxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_A_ADNA300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		5 / 11 ALA A 310
ILE A 320
LEU A 312
LEU A 344
ALA A 333
 None
 1.05A 3kw2A-2zuxA:
undetectable		 3kw2A-2zuxA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_B_ADNB300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		5 / 11 ALA A 310
ILE A 320
LEU A 312
LEU A 344
ALA A 333
 None
 1.04A 3kw2B-2zuxA:
undetectable		 3kw2B-2zuxA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		5 / 12 THR A 537
ALA A 536
ALA A 530
VAL A 552
GLY A 492
 None
 0.86A 3mg0Y-2zuxA:
undetectable
3mg0Z-2zuxA:
undetectable		 3mg0Y-2zuxA:
16.64
3mg0Z-2zuxA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		4 / 5 THR A  91
GLU A  68
THR A  67
HIS A 580
 None
 1.41A 3n58A-2zuxA:
undetectable		 3n58A-2zuxA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		3 / 3 TYR A 514
ASP A 457
ASP A 409
 None
CA  A 635 (-2.9A)
None
 0.86A 3ou6B-2zuxA:
undetectable		 3ou6B-2zuxA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_B_ACRB1_2
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		4 / 5 PRO A 570
ILE A 493
TRP A 548
PHE A  59
 None
 1.50A 3topB-2zuxA:
undetectable		 3topB-2zuxA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UWL_B_FOZB316_0
(THYMIDYLATE SYNTHASE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		5 / 12 LEU A 403
LEU A 586
GLY A 587
ILE A 367
ALA A 368
 None
 0.95A 3uwlB-2zuxA:
undetectable		 3uwlB-2zuxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UWL_D_FOZD316_0
(THYMIDYLATE SYNTHASE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		5 / 12 LEU A 403
LEU A 586
GLY A 587
ILE A 367
ALA A 368
 None
 0.97A 3uwlD-2zuxA:
undetectable		 3uwlD-2zuxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5W_A_8PRA701_2
(G-PROTEIN COUPLED
RECEPTOR KINASE 2)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		3 / 3 LEU A 365
MET A 383
ASP A 386
 None
None
CA  A 637 (-2.9A)
 0.89A 3v5wA-2zuxA:
undetectable		 3v5wA-2zuxA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		4 / 7 LEU A 403
SER A 382
GLU A 422
HIS A 421
 None
None
CA  A 629 (-2.6A)
None
 0.87A 4aq7A-2zuxA:
undetectable		 4aq7A-2zuxA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		4 / 7 LEU A 500
ASP A 607
GLU A 572
HIS A 573
 None
 1.11A 4aq7A-2zuxA:
undetectable		 4aq7A-2zuxA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		5 / 9 GLY A  57
ASP A  95
GLY A  98
VAL A  94
VAL A 123
 None
 1.48A 4c5lB-2zuxA:
undetectable		 4c5lB-2zuxA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_C_UEGC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		5 / 10 GLY A  57
ASP A  95
GLY A  98
VAL A  94
VAL A 123
 None
 1.45A 4c5lC-2zuxA:
undetectable		 4c5lC-2zuxA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA312_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		3 / 3 ARG A 304
HIS A 214
TYR A 326
 None
 1.32A 4fu9A-2zuxA:
undetectable		 4fu9A-2zuxA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_ACTA303_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		3 / 3 TYR A 326
HIS A 214
ARG A 304
 None
 1.09A 4htfA-2zuxA:
undetectable		 4htfA-2zuxA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 453
ALA A 402
PHE A 418
PHE A 432
LEU A 408
 None
 1.21A 4hytA-2zuxA:
undetectable		 4hytA-2zuxA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_C_OBNC2004_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 453
ALA A 402
PHE A 418
PHE A 432
LEU A 408
 None
 1.21A 4hytC-2zuxA:
undetectable		 4hytC-2zuxA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_B_9TPB601_1
(SERUM ALBUMIN)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		5 / 12 PRO A 136
ILE A 168
TYR A 193
LEU A 200
GLY A 273
 None
 1.01A 4l9qB-2zuxA:
undetectable		 4l9qB-2zuxA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		4 / 4 ASN A 208
GLY A 238
ASP A 153
ASP A 187
 None
RAM  A 642 (-3.5A)
CA  A 630 (-2.8A)
RAM  A 641 (-2.7A)
 1.42A 4n49A-2zuxA:
undetectable		 4n49A-2zuxA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		3 / 3 ASN A 300
ASP A 178
ASP A 401
 None
None
CA  A 629 (-2.5A)
 0.69A 4obwD-2zuxA:
undetectable		 4obwD-2zuxA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_B_SAMB401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		5 / 12 SER A 431
GLY A 361
THR A 395
LEU A 306
ASP A 401
 None
None
None
None
CA  A 629 (-2.5A)
 1.38A 4pghB-2zuxA:
undetectable		 4pghB-2zuxA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_H_377H401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		4 / 6 TYR A 595
ASN A 364
GLU A 422
TYR A 326
 RAM  A 639 (-4.7A)
None
CA  A 629 (-2.6A)
None
 1.32A 4twdG-2zuxA:
undetectable
4twdH-2zuxA:
undetectable		 4twdG-2zuxA:
18.07
4twdH-2zuxA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZPH_A_PRLA501_0
(ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
ENDOTHELIAL PAS
DOMAIN-CONTAINING
PROTEIN 1)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		4 / 7 ARG A 288
VAL A 291
LEU A 262
SER A 263
 None
 0.93A 4zphA-2zuxA:
undetectable
4zphB-2zuxA:
undetectable		 4zphA-2zuxA:
20.78
4zphB-2zuxA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		4 / 7 ALA A 426
GLY A 429
SER A 431
GLY A 443
 None
 0.87A 5e26A-2zuxA:
undetectable
5e26B-2zuxA:
undetectable		 5e26A-2zuxA:
20.57
5e26B-2zuxA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		4 / 7 GLY A 429
SER A 431
GLY A 443
ALA A 426
 None
 0.87A 5e26C-2zuxA:
undetectable
5e26D-2zuxA:
undetectable		 5e26C-2zuxA:
20.57
5e26D-2zuxA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_D_PAUD601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		4 / 8 ALA A 426
GLY A 429
SER A 431
GLY A 443
 None
 0.83A 5e26C-2zuxA:
undetectable
5e26D-2zuxA:
undetectable		 5e26C-2zuxA:
20.57
5e26D-2zuxA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_C_PPFC601_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		4 / 6 ARG A  40
ASP A 371
GLY A 372
ASP A 373
 None
CA  A 638 ( 2.7A)
None
CA  A 638 ( 2.6A)
 1.33A 5hp1C-2zuxA:
undetectable		 5hp1C-2zuxA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		5 / 12 ILE A 493
GLY A 492
ALA A 530
ILE A 588
TYR A 584
 None
 1.20A 5igvA-2zuxA:
undetectable		 5igvA-2zuxA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		3 / 3 THR A 395
SER A 394
TYR A 393
 None
 0.77A 5jsdA-2zuxA:
2.6		 5jsdA-2zuxA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		3 / 3 THR A 395
SER A 394
TYR A 393
 None
 0.78A 5jsdB-2zuxA:
undetectable		 5jsdB-2zuxA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		3 / 3 THR A 395
SER A 394
TYR A 393
 None
 0.77A 5jsdC-2zuxA:
2.3		 5jsdC-2zuxA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		3 / 3 THR A 395
SER A 394
TYR A 393
 None
 0.78A 5jseA-2zuxA:
undetectable		 5jseA-2zuxA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		3 / 3 THR A 395
SER A 394
TYR A 393
 None
 0.77A 5jseB-2zuxA:
undetectable		 5jseB-2zuxA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		3 / 3 THR A 395
SER A 394
TYR A 393
 None
 0.77A 5jseC-2zuxA:
2.3		 5jseC-2zuxA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		4 / 5 TYR A 393
ALA A 435
GLN A 419
THR A 405
 None
 1.36A 5n0wB-2zuxA:
undetectable		 5n0wB-2zuxA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		3 / 3 GLY A 186
THR A 141
ASN A 175
 RAM  A 641 ( 4.4A)
None
None
 0.68A 5odiG-2zuxA:
undetectable		 5odiG-2zuxA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_A_CVIA609_0
(ACETYLCHOLINESTERASE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		4 / 6 TYR A 325
ASP A 423
HIS A 421
TYR A 595
 None
None
None
RAM  A 639 (-4.7A)
 1.34A 5ov9A-2zuxA:
undetectable		 5ov9A-2zuxA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		4 / 7 TYR A 325
ASP A 423
HIS A 421
TYR A 595
 None
None
None
RAM  A 639 (-4.7A)
 1.34A 5ov9B-2zuxA:
undetectable		 5ov9B-2zuxA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNI_A_YMZA302_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		5 / 9 VAL A 302
GLY A 259
TYR A 215
ASP A 182
GLY A 183
 None
 1.26A 5zniA-2zuxA:
undetectable		 5zniA-2zuxA:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		3 / 3 GLN A 503
TRP A 468
VAL A 485
 None
 1.14A 6auuA-2zuxA:
undetectable		 6auuA-2zuxA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MHT_D_SAMD328_0
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI)		 2zux YESW PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 429
GLY A 443
ASN A 425
ASP A 449
ASN A 470
 None
 1.00A 6mhtA-2zuxA:
undetectable		 6mhtA-2zuxA:
18.93