SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zv7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_A_STIA201_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 LEU A 253
VAL A 261
GLU A 290
MET A 294
THR A 319
PHE A 321
ASP A 385
 None
 1.21A 1iepA-2zv7A:
26.2		 1iepA-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_A_STIA201_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 LEU A 253
VAL A 261
MET A 294
THR A 319
PHE A 321
ALA A 384
ASP A 385
 None
 1.20A 1iepA-2zv7A:
26.2		 1iepA-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_A_STIA201_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
GLU A 290
MET A 294
THR A 319
PHE A 321
ASP A 385
 None
 1.11A 1iepA-2zv7A:
26.2		 1iepA-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_A_STIA201_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
MET A 294
THR A 319
PHE A 321
ALA A 384
ASP A 385
 None
 1.09A 1iepA-2zv7A:
26.2		 1iepA-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_A_STIA201_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		4 / 6 VAL A 303
ILE A 317
MET A 322
ARG A 366
 None
 1.05A 1iepA-2zv7A:
26.2		 1iepA-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_B_STIB202_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 LEU A 253
VAL A 261
GLU A 290
MET A 294
THR A 319
PHE A 321
ASP A 385
 None
 1.27A 1iepB-2zv7A:
26.3		 1iepB-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_B_STIB202_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 LEU A 253
VAL A 261
MET A 294
THR A 319
PHE A 321
ALA A 384
ASP A 385
 None
 1.26A 1iepB-2zv7A:
26.3		 1iepB-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_B_STIB202_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
GLU A 290
MET A 294
THR A 319
PHE A 321
ASP A 385
 None
 1.14A 1iepB-2zv7A:
26.3		 1iepB-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_B_STIB202_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
MET A 294
THR A 319
PHE A 321
ALA A 384
ASP A 385
 None
 1.12A 1iepB-2zv7A:
26.3		 1iepB-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M17_A_AQ4A999_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
ALA A 273
LYS A 275
GLU A 290
THR A 319
MET A 322
GLY A 325
LEU A 374
 None
 0.59A 1m17A-2zv7A:
32.7		 1m17A-2zv7A:
32.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OPJ_A_STIA3_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
VAL A 303
THR A 319
PHE A 321
ALA A 384
ASP A 385
 None
 0.73A 1opjA-2zv7A:
25.4		 1opjA-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OPJ_A_STIA3_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
VAL A 303
THR A 319
PHE A 321
LEU A 374
ALA A 384
 None
 0.87A 1opjA-2zv7A:
25.4		 1opjA-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OPJ_B_STIB4_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 ALA A 273
MET A 294
VAL A 303
THR A 319
PHE A 321
GLY A 325
ALA A 384
 None
 0.96A 1opjB-2zv7A:
25.3		 1opjB-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OPJ_B_STIB4_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 VAL A 261
ALA A 273
GLU A 290
MET A 294
VAL A 303
THR A 319
PHE A 321
ASP A 385
 None
 1.03A 1opjB-2zv7A:
25.3		 1opjB-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OPJ_B_STIB4_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 VAL A 261
ALA A 273
MET A 294
VAL A 303
THR A 319
PHE A 321
ALA A 384
ASP A 385
 None
 1.06A 1opjB-2zv7A:
25.3		 1opjB-2zv7A:
46.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		4 / 7 ASN A 372
HIS A 365
PHE A 386
ILE A 351
 None
 1.17A 1tdnA-2zv7A:
undetectable		 1tdnA-2zv7A:
20.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XBB_A_STIA1_1
(TYROSINE-PROTEIN
KINASE SYK)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 9 LEU A 253
VAL A 261
ALA A 273
GLY A 325
LEU A 374
 None
 0.44A 1xbbA-2zv7A:
34.0		 1xbbA-2zv7A:
36.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XKK_A_FMMA91_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 ALA A 273
THR A 319
GLY A 325
LEU A 328
ASP A 329
LEU A 374
 None
 0.82A 1xkkA-2zv7A:
24.7		 1xkkA-2zv7A:
31.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XKK_A_FMMA91_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 THR A 319
GLY A 325
LEU A 328
ASP A 329
LEU A 374
ASP A 385
 None
 0.85A 1xkkA-2zv7A:
24.7		 1xkkA-2zv7A:
31.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GQG_A_1N1A501_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		11 / 12 LEU A 253
ALA A 273
GLU A 290
MET A 294
VAL A 303
ILE A 317
THR A 319
PHE A 321
GLY A 325
LEU A 374
ALA A 384
 None
 0.44A 2gqgA-2zv7A:
35.0		 2gqgA-2zv7A:
47.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GQG_A_1N1A501_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		10 / 12 LEU A 253
ALA A 273
LYS A 275
GLU A 290
MET A 294
VAL A 303
ILE A 317
PHE A 321
GLY A 325
ALA A 384
 None
 0.52A 2gqgA-2zv7A:
35.0		 2gqgA-2zv7A:
47.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GQG_B_1N1B502_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		9 / 12 LEU A 253
VAL A 261
ALA A 273
GLU A 290
MET A 294
VAL A 303
ILE A 317
GLY A 325
ALA A 384
 None
 0.65A 2gqgB-2zv7A:
34.8		 2gqgB-2zv7A:
47.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GQG_B_1N1B502_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		10 / 12 LEU A 253
VAL A 261
ALA A 273
MET A 294
VAL A 303
ILE A 317
THR A 319
GLY A 325
LEU A 374
ALA A 384
 None
 0.68A 2gqgB-2zv7A:
34.8		 2gqgB-2zv7A:
47.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_A_STIA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 ALA A 273
MET A 294
THR A 319
PHE A 321
GLY A 325
LEU A 374
ALA A 384
 None
 0.87A 2hyyA-2zv7A:
31.8		 2hyyA-2zv7A:
46.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_A_STIA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
MET A 294
THR A 319
PHE A 321
ALA A 384
ASP A 385
 None
 1.09A 2hyyA-2zv7A:
31.8		 2hyyA-2zv7A:
46.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_A_STIA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
MET A 294
THR A 319
PHE A 321
LEU A 374
ALA A 384
 None
 1.13A 2hyyA-2zv7A:
31.8		 2hyyA-2zv7A:
46.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_B_STIB600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 ALA A 273
MET A 294
THR A 319
PHE A 321
GLY A 325
LEU A 374
ALA A 384
 None
 0.86A 2hyyB-2zv7A:
31.9		 2hyyB-2zv7A:
46.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_B_STIB600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
MET A 294
THR A 319
PHE A 321
ALA A 384
ASP A 385
 None
 1.04A 2hyyB-2zv7A:
31.9		 2hyyB-2zv7A:
46.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_B_STIB600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
MET A 294
THR A 319
PHE A 321
LEU A 374
ALA A 384
 None
 1.10A 2hyyB-2zv7A:
31.9		 2hyyB-2zv7A:
46.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_B_STIB600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		4 / 6 LEU A 253
LYS A 275
VAL A 303
ILE A 317
 None
 0.92A 2hyyB-2zv7A:
31.9		 2hyyB-2zv7A:
46.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_C_STIC600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
GLU A 290
VAL A 303
THR A 319
PHE A 321
ASP A 385
 None
 0.93A 2hyyC-2zv7A:
26.3		 2hyyC-2zv7A:
46.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_C_STIC600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
VAL A 303
THR A 319
PHE A 321
ALA A 384
ASP A 385
 None
 0.75A 2hyyC-2zv7A:
26.3		 2hyyC-2zv7A:
46.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_C_STIC600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 VAL A 261
ALA A 273
VAL A 303
THR A 319
PHE A 321
GLY A 325
LEU A 374
ALA A 384
 None
 0.83A 2hyyC-2zv7A:
26.3		 2hyyC-2zv7A:
46.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_C_STIC600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		4 / 6 LEU A 253
LYS A 275
MET A 294
ILE A 317
 None
 0.95A 2hyyC-2zv7A:
26.3		 2hyyC-2zv7A:
46.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_D_STID600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 VAL A 261
ALA A 273
GLU A 290
MET A 294
ILE A 317
THR A 319
PHE A 321
ASP A 385
 None
 1.08A 2hyyD-2zv7A:
31.9		 2hyyD-2zv7A:
46.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_D_STID600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 VAL A 261
ALA A 273
MET A 294
ILE A 317
THR A 319
PHE A 321
ALA A 384
ASP A 385
 None
 0.99A 2hyyD-2zv7A:
31.9		 2hyyD-2zv7A:
46.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_D_STID600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 VAL A 261
ALA A 273
MET A 294
ILE A 317
THR A 319
PHE A 321
LEU A 374
ALA A 384
 None
 1.08A 2hyyD-2zv7A:
31.9		 2hyyD-2zv7A:
46.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ITO_A_IREA2020_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
ALA A 273
LYS A 275
GLU A 290
MET A 294
GLY A 325
ASP A 329
LEU A 374
 None
 0.77A 2itoA-2zv7A:
32.8		 2itoA-2zv7A:
33.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ITO_A_IREA2020_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
ALA A 273
LYS A 275
MET A 294
THR A 319
GLY A 325
ASP A 329
LEU A 374
 None
 0.76A 2itoA-2zv7A:
32.8		 2itoA-2zv7A:
33.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ITY_A_IREA2020_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
GLY A 254
VAL A 261
ALA A 273
LYS A 275
THR A 319
GLY A 325
LEU A 374
 None
 0.58A 2ityA-2zv7A:
32.9		 2ityA-2zv7A:
33.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ITY_A_IREA2020_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
ALA A 273
LYS A 275
MET A 294
THR A 319
GLY A 325
LEU A 374
 None
 0.63A 2ityA-2zv7A:
32.9		 2ityA-2zv7A:
33.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ITZ_A_IREA2021_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		9 / 12 LEU A 253
VAL A 261
ALA A 273
LYS A 275
GLU A 290
MET A 294
GLY A 325
ASP A 329
LEU A 374
 None
 0.71A 2itzA-2zv7A:
29.0		 2itzA-2zv7A:
33.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ITZ_A_IREA2021_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		9 / 12 LEU A 253
VAL A 261
ALA A 273
LYS A 275
MET A 294
THR A 319
GLY A 325
ASP A 329
LEU A 374
 None
 0.74A 2itzA-2zv7A:
29.0		 2itzA-2zv7A:
33.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_CCSB417_0
(ESTROGEN RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		3 / 3 GLN A 350
LYS A 382
VAL A 373
 None
 0.83A 2jfaB-2zv7A:
undetectable		 2jfaB-2zv7A:
20.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OIQ_A_STIA1001_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 VAL A 261
ALA A 273
MET A 294
ILE A 317
THR A 319
GLY A 325
LEU A 374
ALA A 384
 None
 0.93A 2oiqA-2zv7A:
34.7		 2oiqA-2zv7A:
64.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PL0_A_STIA200_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE LCK)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 VAL A 261
ALA A 273
GLU A 290
MET A 294
VAL A 303
ILE A 317
THR A 319
ASP A 385
 None
 0.98A 2pl0A-2zv7A:
34.3		 2pl0A-2zv7A:
71.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PL0_A_STIA200_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE LCK)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 VAL A 261
ALA A 273
LYS A 275
GLU A 290
MET A 294
VAL A 303
ILE A 317
ASP A 385
 None
 0.97A 2pl0A-2zv7A:
34.3		 2pl0A-2zv7A:
71.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PL0_A_STIA200_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE LCK)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 VAL A 261
ALA A 273
MET A 294
VAL A 303
ILE A 317
THR A 319
ALA A 384
ASP A 385
 None
 0.99A 2pl0A-2zv7A:
34.3		 2pl0A-2zv7A:
71.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WGJ_A_VGHA2346_1
(HEPATOCYTE GROWTH
FACTOR RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 VAL A 261
ALA A 273
MET A 322
GLY A 325
ALA A 384
ASP A 385
 None
 0.72A 2wgjA-2zv7A:
31.0		 2wgjA-2zv7A:
36.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 12 ILE A 358
PHE A 386
LEU A 327
ILE A 383
MET A 355
 None
 1.34A 2xkwB-2zv7A:
undetectable		 2xkwB-2zv7A:
21.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XP2_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 9 LEU A 253
VAL A 261
ALA A 273
MET A 322
GLY A 325
LEU A 374
ASP A 385
 None
 0.50A 2xp2A-2zv7A:
32.8		 2xp2A-2zv7A:
35.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y6O_A_1N1A1892_1
(EPHRIN TYPE-A
RECEPTOR 4)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		9 / 12 LYS A 251
ALA A 273
LYS A 275
GLU A 290
MET A 294
ILE A 317
THR A 319
GLY A 325
LEU A 374
 None
 0.96A 2y6oA-2zv7A:
27.1		 2y6oA-2zv7A:
41.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_C_B49C1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 10 VAL A 261
ALA A 273
MET A 322
GLY A 325
ASP A 329
LEU A 374
 None
 0.57A 2y7jC-2zv7A:
26.8		 2y7jC-2zv7A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_D_B49D1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 10 VAL A 261
ALA A 273
MET A 322
GLY A 325
ASP A 329
LEU A 374
 None
 0.42A 2y7jD-2zv7A:
27.1		 2y7jD-2zv7A:
23.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZVA_A_1N1A513_1
(TYROSINE-PROTEIN
KINASE LYN)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		12 / 12 LEU A 253
ALA A 273
LYS A 275
GLU A 290
MET A 294
VAL A 303
ILE A 317
THR A 319
MET A 322
GLY A 325
LEU A 374
ALA A 384
 None
 0.46A 2zvaA-2zv7A:
42.5		 2zvaA-2zv7A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AOX_A_EMHA901_1
(ALK TYROSINE KINASE
RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 10 LEU A 253
ALA A 273
LYS A 275
VAL A 303
MET A 322
GLY A 325
LEU A 374
 None
 0.38A 3aoxA-2zv7A:
31.4		 3aoxA-2zv7A:
34.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3C7Q_A_XINA1172_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 LEU A 253
ALA A 273
LYS A 275
VAL A 303
PHE A 321
GLY A 325
LEU A 374
 None
 0.86A 3c7qA-2zv7A:
25.7		 3c7qA-2zv7A:
37.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3C7Q_A_XINA1172_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 LEU A 253
GLY A 254
ALA A 273
LYS A 275
PHE A 321
GLY A 325
LEU A 374
 None
 0.83A 3c7qA-2zv7A:
25.7		 3c7qA-2zv7A:
37.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_A_NILA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 10 LEU A 253
VAL A 261
LYS A 275
VAL A 303
ILE A 317
 None
 0.80A 3cs9A-2zv7A:
25.9		 3cs9A-2zv7A:
47.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_A_NILA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 10 LEU A 253
VAL A 261
VAL A 303
ILE A 317
PHE A 321
ASP A 385
 None
 0.79A 3cs9A-2zv7A:
25.9		 3cs9A-2zv7A:
47.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_A_NILA600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 ALA A 273
LEU A 302
THR A 319
GLY A 325
HIS A 365
LEU A 374
ALA A 384
 None
 0.60A 3cs9A-2zv7A:
25.9		 3cs9A-2zv7A:
47.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_A_NILA600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 ALA A 273
MET A 294
LEU A 302
THR A 319
HIS A 365
ALA A 384
 None
 0.78A 3cs9A-2zv7A:
25.9		 3cs9A-2zv7A:
47.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_B_NILB600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 ALA A 273
LEU A 302
THR A 319
GLY A 325
HIS A 365
ALA A 384
 None
 0.49A 3cs9B-2zv7A:
26.7		 3cs9B-2zv7A:
47.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_B_NILB600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 ALA A 273
MET A 294
LEU A 302
THR A 319
HIS A 365
ALA A 384
 None
 0.79A 3cs9B-2zv7A:
26.7		 3cs9B-2zv7A:
47.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_B_NILB600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 9 LEU A 253
VAL A 261
LYS A 275
VAL A 303
ILE A 317
 None
 0.85A 3cs9B-2zv7A:
26.7		 3cs9B-2zv7A:
47.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_C_NILC600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 ALA A 273
GLU A 290
MET A 294
LEU A 302
THR A 319
PHE A 321
ASP A 385
 None
 1.10A 3cs9C-2zv7A:
31.5		 3cs9C-2zv7A:
47.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_C_NILC600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 ALA A 273
MET A 294
LEU A 302
THR A 319
PHE A 321
HIS A 365
ALA A 384
ASP A 385
 None
 1.05A 3cs9C-2zv7A:
31.5		 3cs9C-2zv7A:
47.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_C_NILC600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 9 LEU A 253
VAL A 261
ILE A 317
MET A 322
VAL A 373
 None
 1.22A 3cs9C-2zv7A:
31.5		 3cs9C-2zv7A:
47.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_C_NILC600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 9 LEU A 253
VAL A 261
LYS A 275
ILE A 317
VAL A 373
 None
 1.23A 3cs9C-2zv7A:
31.5		 3cs9C-2zv7A:
47.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_C_NILC600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 9 LEU A 253
VAL A 261
LYS A 275
VAL A 303
ILE A 317
 None
 0.78A 3cs9C-2zv7A:
31.5		 3cs9C-2zv7A:
47.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_C_NILC600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 9 LEU A 253
VAL A 261
VAL A 303
ILE A 317
MET A 322
 None
 0.79A 3cs9C-2zv7A:
31.5		 3cs9C-2zv7A:
47.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_D_NILD600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 12 ALA A 273
GLU A 290
MET A 294
THR A 319
PHE A 321
 None
 0.60A 3cs9D-2zv7A:
25.8		 3cs9D-2zv7A:
47.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_D_NILD600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 ALA A 273
LEU A 302
THR A 319
PHE A 321
GLY A 325
HIS A 365
ALA A 384
 None
 0.58A 3cs9D-2zv7A:
25.8		 3cs9D-2zv7A:
47.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_D_NILD600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 ALA A 273
MET A 294
LEU A 302
THR A 319
PHE A 321
HIS A 365
ALA A 384
 None
 0.73A 3cs9D-2zv7A:
25.8		 3cs9D-2zv7A:
47.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G5D_A_1N1A1_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		10 / 12 LEU A 253
VAL A 261
ALA A 273
GLU A 290
MET A 294
VAL A 303
ILE A 317
THR A 319
GLY A 325
ALA A 384
 None
 0.68A 3g5dA-2zv7A:
36.1		 3g5dA-2zv7A:
64.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G5D_A_1N1A1_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		10 / 12 LEU A 253
VAL A 261
ALA A 273
MET A 294
VAL A 303
ILE A 317
THR A 319
GLY A 325
LEU A 374
ALA A 384
 None
 0.68A 3g5dA-2zv7A:
36.1		 3g5dA-2zv7A:
64.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G5D_B_1N1B1_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		11 / 12 LEU A 253
VAL A 261
ALA A 273
LYS A 275
GLU A 290
MET A 294
VAL A 303
THR A 319
GLY A 325
LEU A 374
ALA A 384
 None
 0.66A 3g5dB-2zv7A:
29.0		 3g5dB-2zv7A:
64.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 12 VAL A 261
ALA A 273
LEU A 293
THR A 319
HIS A 365
 None
 1.03A 3gcsA-2zv7A:
20.1		 3gcsA-2zv7A:
25.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 12 VAL A 261
ALA A 273
THR A 319
ILE A 358
HIS A 365
 None
 0.97A 3gcsA-2zv7A:
20.1		 3gcsA-2zv7A:
25.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GP0_A_NILA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 11)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 VAL A 261
ALA A 273
LEU A 293
THR A 319
HIS A 365
ASP A 385
 None
 0.98A 3gp0A-2zv7A:
21.8		 3gp0A-2zv7A:
26.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GVU_A_STIA1001_1
(TYROSINE-PROTEIN
KINASE ABL2)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
ALA A 273
GLU A 290
MET A 294
VAL A 303
THR A 319
ASP A 385
 None
 1.04A 3gvuA-2zv7A:
31.8		 3gvuA-2zv7A:
43.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GVU_A_STIA1001_1
(TYROSINE-PROTEIN
KINASE ABL2)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
ALA A 273
MET A 294
VAL A 303
THR A 319
ALA A 384
ASP A 385
 None
 1.05A 3gvuA-2zv7A:
31.8		 3gvuA-2zv7A:
43.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GVU_A_STIA1001_1
(TYROSINE-PROTEIN
KINASE ABL2)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
ALA A 273
MET A 294
VAL A 303
THR A 319
LEU A 374
ALA A 384
 None
 1.02A 3gvuA-2zv7A:
31.8		 3gvuA-2zv7A:
43.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEG_A_BAXA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 12 VAL A 261
ALA A 273
LYS A 275
THR A 319
ILE A 358
 None
 0.78A 3hegA-2zv7A:
20.7		 3hegA-2zv7A:
26.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK3_A_0LIA1_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 12 ALA A 273
LEU A 302
HIS A 365
LEU A 374
ALA A 384
 None
 0.43A 3ik3A-2zv7A:
31.4		 3ik3A-2zv7A:
45.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK3_B_0LIB2_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 12 ALA A 273
LEU A 302
HIS A 365
LEU A 374
ALA A 384
 None
 0.44A 3ik3B-2zv7A:
25.6		 3ik3B-2zv7A:
45.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K54_A_1N1A1_1
(TYROSINE-PROTEIN
KINASE BTK)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		10 / 12 LEU A 253
ALA A 273
LYS A 275
GLU A 290
MET A 294
VAL A 303
ILE A 317
THR A 319
GLY A 325
LEU A 374
 None
 0.61A 3k54A-2zv7A:
15.1		 3k54A-2zv7A:
40.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K5V_A_STIA2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 ALA A 273
MET A 294
THR A 319
PHE A 321
GLY A 325
LEU A 374
ALA A 384
 None
 0.92A 3k5vA-2zv7A:
25.3		 3k5vA-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K5V_A_STIA2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
GLU A 290
MET A 294
THR A 319
PHE A 321
ASP A 385
 None
 1.05A 3k5vA-2zv7A:
25.3		 3k5vA-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K5V_A_STIA2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
MET A 294
THR A 319
PHE A 321
ALA A 384
ASP A 385
 None
 1.07A 3k5vA-2zv7A:
25.3		 3k5vA-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K5V_A_STIA2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
MET A 294
THR A 319
PHE A 321
LEU A 374
ALA A 384
 None
 1.14A 3k5vA-2zv7A:
25.3		 3k5vA-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K5V_A_STIA2_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		4 / 6 LEU A 253
LYS A 275
VAL A 303
ILE A 317
 None
 0.83A 3k5vA-2zv7A:
25.3		 3k5vA-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K5V_B_STIB2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 ALA A 273
MET A 294
THR A 319
PHE A 321
GLY A 325
LEU A 374
ALA A 384
 None
 0.89A 3k5vB-2zv7A:
31.0		 3k5vB-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K5V_B_STIB2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
GLU A 290
MET A 294
THR A 319
PHE A 321
ASP A 385
 None
 1.06A 3k5vB-2zv7A:
31.0		 3k5vB-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K5V_B_STIB2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
MET A 294
THR A 319
PHE A 321
ALA A 384
ASP A 385
 None
 1.07A 3k5vB-2zv7A:
31.0		 3k5vB-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K5V_B_STIB2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
MET A 294
THR A 319
PHE A 321
LEU A 374
ALA A 384
 None
 1.12A 3k5vB-2zv7A:
31.0		 3k5vB-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MIY_A_B49A1_1
(TYROSINE-PROTEIN
KINASE ITK/TSK)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 11 ALA A 273
LYS A 275
VAL A 303
PHE A 321
MET A 322
GLY A 325
LEU A 374
 None
 0.57A 3miyA-2zv7A:
32.9		 3miyA-2zv7A:
41.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MIY_B_B49B2_1
(TYROSINE-PROTEIN
KINASE ITK/TSK)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 9 ALA A 273
LYS A 275
PHE A 321
MET A 322
GLY A 325
LEU A 374
 None
 0.41A 3miyB-2zv7A:
32.8		 3miyB-2zv7A:
41.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MS9_A_STIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
ALA A 273
GLU A 290
MET A 294
THR A 319
PHE A 321
ASP A 385
 None
 1.09A 3ms9A-2zv7A:
26.2		 3ms9A-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MS9_A_STIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
ALA A 273
MET A 294
THR A 319
PHE A 321
ALA A 384
ASP A 385
 None
 1.09A 3ms9A-2zv7A:
26.2		 3ms9A-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MS9_A_STIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
ALA A 273
MET A 294
THR A 319
PHE A 321
LEU A 374
ALA A 384
 None
 1.16A 3ms9A-2zv7A:
26.2		 3ms9A-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MS9_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		4 / 6 VAL A 303
ILE A 317
MET A 322
ARG A 366
 None
 1.01A 3ms9A-2zv7A:
26.2		 3ms9A-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MS9_B_STIB1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
ALA A 273
MET A 294
THR A 319
PHE A 321
GLY A 325
LEU A 374
ALA A 384
 None
 1.14A 3ms9B-2zv7A:
26.1		 3ms9B-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MS9_B_STIB1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
ALA A 273
GLU A 290
MET A 294
THR A 319
PHE A 321
ASP A 385
 None
 1.14A 3ms9B-2zv7A:
26.1		 3ms9B-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MS9_B_STIB1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
ALA A 273
MET A 294
THR A 319
PHE A 321
ALA A 384
ASP A 385
 None
 1.14A 3ms9B-2zv7A:
26.1		 3ms9B-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MS9_B_STIB1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
ALA A 273
MET A 294
THR A 319
PHE A 321
LEU A 374
ALA A 384
 None
 1.20A 3ms9B-2zv7A:
26.1		 3ms9B-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_A_STIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
ALA A 273
GLU A 290
MET A 294
THR A 319
PHE A 321
ASP A 385
 None
 1.13A 3mssA-2zv7A:
31.4		 3mssA-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_A_STIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
ALA A 273
MET A 294
THR A 319
PHE A 321
ALA A 384
ASP A 385
 None
 1.12A 3mssA-2zv7A:
31.4		 3mssA-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_A_STIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
ALA A 273
MET A 294
THR A 319
PHE A 321
LEU A 374
ALA A 384
 None
 1.20A 3mssA-2zv7A:
31.4		 3mssA-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		4 / 6 VAL A 303
ILE A 317
MET A 322
ARG A 366
 None
 1.03A 3mssA-2zv7A:
31.4		 3mssA-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_B_STIB1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 VAL A 261
ALA A 273
THR A 319
PHE A 321
ALA A 384
ASP A 385
 None
 0.65A 3mssB-2zv7A:
31.5		 3mssB-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		4 / 7 VAL A 303
ILE A 317
MET A 322
ARG A 366
 None
 1.06A 3mssB-2zv7A:
31.5		 3mssB-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_C_STIC1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
ALA A 273
GLU A 290
MET A 294
THR A 319
PHE A 321
ASP A 385
 None
 1.14A 3mssC-2zv7A:
31.3		 3mssC-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_C_STIC1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
ALA A 273
MET A 294
THR A 319
PHE A 321
ALA A 384
ASP A 385
 None
 1.12A 3mssC-2zv7A:
31.3		 3mssC-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_C_STIC1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 LEU A 253
VAL A 261
ALA A 273
THR A 319
PHE A 321
LEU A 374
ALA A 384
 None
 0.91A 3mssC-2zv7A:
31.3		 3mssC-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_C_STIC1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		4 / 6 VAL A 303
ILE A 317
MET A 322
ARG A 366
 None
 1.08A 3mssC-2zv7A:
31.3		 3mssC-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_D_STID1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 LEU A 253
ALA A 273
GLU A 290
MET A 294
THR A 319
PHE A 321
ASP A 385
 None
 1.16A 3mssD-2zv7A:
26.3		 3mssD-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_D_STID1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 LEU A 253
ALA A 273
MET A 294
THR A 319
PHE A 321
ALA A 384
ASP A 385
 None
 1.15A 3mssD-2zv7A:
26.3		 3mssD-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_D_STID1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
ALA A 273
MET A 294
THR A 319
PHE A 321
GLY A 325
LEU A 374
ALA A 384
 None
 1.18A 3mssD-2zv7A:
26.3		 3mssD-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_D_STID1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		4 / 6 VAL A 261
LYS A 275
VAL A 303
ILE A 317
 None
 0.79A 3mssD-2zv7A:
26.3		 3mssD-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_D_STID1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		4 / 6 VAL A 261
VAL A 303
ILE A 317
MET A 322
 None
 0.78A 3mssD-2zv7A:
26.3		 3mssD-2zv7A:
46.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OCT_A_1N1A663_1
(TYROSINE-PROTEIN
KINASE BTK)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
ALA A 273
LYS A 275
MET A 294
THR A 319
GLY A 325
GLU A 335
 None
 1.19A 3octA-2zv7A:
32.2		 3octA-2zv7A:
42.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OCT_A_1N1A663_1
(TYROSINE-PROTEIN
KINASE BTK)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		9 / 12 LEU A 253
VAL A 261
ALA A 273
LYS A 275
VAL A 303
THR A 319
GLY A 325
GLU A 335
LEU A 374
 None
 0.81A 3octA-2zv7A:
32.2		 3octA-2zv7A:
42.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OEZ_B_STIB601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
MET A 294
ILE A 317
THR A 319
LEU A 374
ALA A 384
 None
 0.78A 3oezB-2zv7A:
27.4		 3oezB-2zv7A:
64.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OG7_A_032A1_1
(AKAP9-BRAF FUSION
PROTEIN)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 12 VAL A 261
ALA A 273
LYS A 275
THR A 319
PHE A 386
 None
 0.71A 3og7A-2zv7A:
27.6		 3og7A-2zv7A:
34.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_1
(P38A)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 GLY A 254
VAL A 261
ALA A 273
LYS A 275
THR A 319
LEU A 374
 None
 1.01A 3ohtA-2zv7A:
17.0		 3ohtA-2zv7A:
23.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXZ_A_0LIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 ALA A 273
GLU A 290
MET A 294
LEU A 302
VAL A 303
THR A 319
HIS A 365
ASP A 385
 None
 1.15A 3oxzA-2zv7A:
26.2		 3oxzA-2zv7A:
46.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXZ_A_0LIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 ALA A 273
MET A 294
LEU A 302
VAL A 303
THR A 319
GLY A 325
HIS A 365
ALA A 384
 None
 0.74A 3oxzA-2zv7A:
26.2		 3oxzA-2zv7A:
46.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXZ_A_0LIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 ALA A 273
MET A 294
LEU A 302
VAL A 303
THR A 319
HIS A 365
ALA A 384
ASP A 385
 None
 1.05A 3oxzA-2zv7A:
26.2		 3oxzA-2zv7A:
46.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXZ_A_0LIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 9 LEU A 253
ILE A 317
MET A 322
LEU A 374
VAL A 373
 None
 1.44A 3oxzA-2zv7A:
26.2		 3oxzA-2zv7A:
46.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PYY_A_STIA3_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 LEU A 253
VAL A 261
ALA A 273
GLU A 290
PHE A 321
ASP A 385
 None
 1.07A 3pyyA-2zv7A:
26.3		 3pyyA-2zv7A:
43.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PYY_A_STIA3_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 VAL A 261
ALA A 273
MET A 294
THR A 319
PHE A 321
ASP A 385
 None
 1.06A 3pyyA-2zv7A:
26.3		 3pyyA-2zv7A:
43.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PYY_A_STIA3_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 VAL A 261
ALA A 273
THR A 319
PHE A 321
ALA A 384
ASP A 385
 None
 0.69A 3pyyA-2zv7A:
26.3		 3pyyA-2zv7A:
43.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PYY_B_STIB4_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
ALA A 273
GLU A 290
MET A 294
VAL A 303
THR A 319
ASP A 385
 None
 1.09A 3pyyB-2zv7A:
31.5		 3pyyB-2zv7A:
43.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PYY_B_STIB4_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
ALA A 273
MET A 294
VAL A 303
THR A 319
ALA A 384
ASP A 385
 None
 1.09A 3pyyB-2zv7A:
31.5		 3pyyB-2zv7A:
43.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PYY_B_STIB4_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
ALA A 273
MET A 294
VAL A 303
THR A 319
LEU A 374
ALA A 384
 None
 1.08A 3pyyB-2zv7A:
31.5		 3pyyB-2zv7A:
43.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		4 / 8 ALA A 352
LEU A 493
ASP A 498
ASP A 346
 None
 0.94A 3qj7A-2zv7A:
undetectable
3qj7D-2zv7A:
undetectable		 3qj7A-2zv7A:
20.81
3qj7D-2zv7A:
20.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QLG_A_1N1A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		10 / 12 LEU A 253
VAL A 261
ALA A 273
GLU A 290
MET A 294
VAL A 303
THR A 319
GLY A 325
LEU A 374
ALA A 384
 None
 0.64A 3qlgA-2zv7A:
35.6		 3qlgA-2zv7A:
64.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QLG_A_1N1A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
ALA A 273
LYS A 275
GLU A 290
MET A 294
VAL A 303
THR A 319
 None
 0.62A 3qlgA-2zv7A:
35.6		 3qlgA-2zv7A:
64.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QLG_B_1N1B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		10 / 12 LEU A 253
VAL A 261
ALA A 273
GLU A 290
MET A 294
VAL A 303
THR A 319
GLY A 325
LEU A 374
ALA A 384
 None
 0.64A 3qlgB-2zv7A:
28.5		 3qlgB-2zv7A:
64.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QLG_B_1N1B601_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		4 / 4 LYS A 275
ILE A 317
MET A 322
LYS A 324
 None
 0.53A 3qlgB-2zv7A:
28.5		 3qlgB-2zv7A:
64.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SXR_A_1N1A1_1
(CYTOPLASMIC
TYROSINE-PROTEIN
KINASE BMX)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		9 / 12 LEU A 253
VAL A 261
ALA A 273
MET A 294
VAL A 303
ILE A 317
THR A 319
GLY A 325
LEU A 374
 None
 0.63A 3sxrA-2zv7A:
33.9		 3sxrA-2zv7A:
43.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SXR_B_1N1B2_1
(CYTOPLASMIC
TYROSINE-PROTEIN
KINASE BMX)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
ALA A 273
MET A 294
VAL A 303
THR A 319
GLY A 325
LEU A 374
 None
 0.69A 3sxrB-2zv7A:
33.5		 3sxrB-2zv7A:
43.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UE4_A_DB8A601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		10 / 12 LEU A 253
ALA A 273
LYS A 275
VAL A 303
ILE A 317
THR A 319
PHE A 321
MET A 322
GLY A 325
LEU A 374
 None
 0.59A 3ue4A-2zv7A:
34.0		 3ue4A-2zv7A:
45.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UE4_B_DB8B601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		10 / 12 LEU A 253
VAL A 261
ALA A 273
MET A 294
VAL A 303
ILE A 317
THR A 319
PHE A 321
GLY A 325
LEU A 374
 None
 0.72A 3ue4B-2zv7A:
33.7		 3ue4B-2zv7A:
45.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_C_ACHC301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		4 / 8 TYR A 460
TRP A 480
ARG A 464
MET A 476
 None
 1.48A 3wipC-2zv7A:
undetectable
3wipD-2zv7A:
undetectable		 3wipC-2zv7A:
20.56
3wipD-2zv7A:
20.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZBF_A_VGHA3000_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ROS)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 LEU A 253
ALA A 273
MET A 322
GLY A 325
LEU A 374
ASP A 385
 None
 0.50A 3zbfA-2zv7A:
33.1		 3zbfA-2zv7A:
38.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AGD_A_B49A2000_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 11 LEU A 253
ALA A 273
LYS A 275
VAL A 303
PHE A 321
GLY A 325
LEU A 374
 None
 0.83A 4agdA-2zv7A:
29.9		 4agdA-2zv7A:
34.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ANQ_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 9 LEU A 253
VAL A 261
ALA A 273
MET A 322
GLY A 325
LEU A 374
ALA A 384
ASP A 385
 None
 0.48A 4anqA-2zv7A:
32.5		 4anqA-2zv7A:
34.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ANS_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 9 LEU A 253
VAL A 261
ALA A 273
MET A 322
GLY A 325
LEU A 374
ALA A 384
ASP A 385
 None
 0.47A 4ansA-2zv7A:
32.4		 4ansA-2zv7A:
34.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_A_0LIA1000_1
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 ALA A 273
LYS A 275
GLU A 290
ILE A 317
THR A 319
HIS A 365
ASP A 385
 None
 1.01A 4c8bA-2zv7A:
26.9		 4c8bA-2zv7A:
26.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_A_0LIA1000_1
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 ALA A 273
LYS A 275
ILE A 317
THR A 319
HIS A 365
LEU A 374
ALA A 384
ASP A 385
 None
 0.81A 4c8bA-2zv7A:
26.9		 4c8bA-2zv7A:
26.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CKI_A_ADNA2022_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 11 LEU A 253
GLY A 254
VAL A 261
ALA A 273
GLY A 325
SER A 326
LEU A 374
 None
 0.66A 4ckiA-2zv7A:
15.7		 4ckiA-2zv7A:
35.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CSV_A_STIA1265_1
(SRC-ABL TYROSINE
KINASE ANCESTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
GLU A 290
MET A 294
VAL A 303
THR A 319
ASP A 385
 None
 0.96A 4csvA-2zv7A:
27.2		 4csvA-2zv7A:
57.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CSV_A_STIA1265_1
(SRC-ABL TYROSINE
KINASE ANCESTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
MET A 294
VAL A 303
THR A 319
ALA A 384
ASP A 385
 None
 0.95A 4csvA-2zv7A:
27.2		 4csvA-2zv7A:
57.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HJO_A_AQ4A1001_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
ALA A 273
LYS A 275
THR A 319
MET A 322
GLY A 325
LEU A 374
 None
 0.72A 4hjoA-2zv7A:
30.1		 4hjoA-2zv7A:
32.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I22_A_IREA9001_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
GLY A 254
VAL A 261
ALA A 273
LYS A 275
GLY A 325
ASP A 329
LEU A 374
 None
 0.80A 4i22A-2zv7A:
28.6		 4i22A-2zv7A:
32.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 12 LEU A 432
LEU A 433
LEU A 493
ILE A 383
HIS A 365
 None
 1.00A 4j24A-2zv7A:
undetectable		 4j24A-2zv7A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 12 LEU A 432
LEU A 433
LEU A 493
ILE A 383
HIS A 365
 None
 1.01A 4j24B-2zv7A:
undetectable		 4j24B-2zv7A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KS8_A_B49A701_1
(SERINE/THREONINE-PRO
TEIN KINASE PAK 6)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 10 ALA A 273
VAL A 303
PHE A 321
GLY A 325
LEU A 374
 None
 0.33A 4ks8A-2zv7A:
27.0		 4ks8A-2zv7A:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_A_8PRA601_1
(RHODOPSIN KINASE)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		4 / 7 VAL A 261
ALA A 273
MET A 322
LEU A 374
 None
 0.74A 4l9iA-2zv7A:
8.9		 4l9iA-2zv7A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_B_8PRB601_1
(RHODOPSIN KINASE)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 8 VAL A 261
ALA A 273
LYS A 275
MET A 322
ASP A 329
 None
 1.19A 4l9iB-2zv7A:
23.5		 4l9iB-2zv7A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_B_8PRB601_1
(RHODOPSIN KINASE)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 8 VAL A 261
ALA A 273
LYS A 275
MET A 322
LEU A 374
 None
 0.71A 4l9iB-2zv7A:
23.5		 4l9iB-2zv7A:
18.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MKC_A_4MKA1503_1
(ALK TYROSINE KINASE
RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 LEU A 253
VAL A 261
ALA A 273
LYS A 275
GLY A 325
LEU A 374
ASP A 385
 None
 0.65A 4mkcA-2zv7A:
32.3		 4mkcA-2zv7A:
34.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXO_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		10 / 12 LEU A 253
VAL A 261
ALA A 273
GLU A 290
MET A 294
VAL A 303
ILE A 317
THR A 319
GLY A 325
ASP A 385
 None
 0.60A 4mxoA-2zv7A:
37.5		 4mxoA-2zv7A:
64.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXO_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		10 / 12 LEU A 253
VAL A 261
ALA A 273
LYS A 275
GLU A 290
MET A 294
ILE A 317
THR A 319
GLY A 325
ASP A 385
 None
 0.69A 4mxoA-2zv7A:
37.5		 4mxoA-2zv7A:
64.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXO_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		10 / 12 LEU A 253
VAL A 261
ALA A 273
GLU A 290
VAL A 303
ILE A 317
THR A 319
GLY A 325
LEU A 374
ASP A 385
 None
 0.60A 4mxoB-2zv7A:
38.0		 4mxoB-2zv7A:
64.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXO_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
ALA A 273
LYS A 275
GLU A 290
ILE A 317
GLY A 325
ASP A 385
 None
 0.79A 4mxoB-2zv7A:
38.0		 4mxoB-2zv7A:
64.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXX_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		9 / 12 LEU A 253
ALA A 273
LYS A 275
GLU A 290
MET A 294
VAL A 303
ILE A 317
THR A 319
GLY A 325
 None
 0.75A 4mxxA-2zv7A:
37.2		 4mxxA-2zv7A:
64.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXX_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		9 / 12 LEU A 253
ALA A 273
LYS A 275
MET A 294
VAL A 303
ILE A 317
THR A 319
GLY A 325
LEU A 374
 None
 0.67A 4mxxA-2zv7A:
37.2		 4mxxA-2zv7A:
64.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXX_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		9 / 12 LEU A 253
VAL A 261
ALA A 273
LYS A 275
VAL A 303
THR A 319
MET A 322
GLY A 325
LEU A 374
 None
 0.58A 4mxxB-2zv7A:
34.9		 4mxxB-2zv7A:
64.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXY_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		9 / 12 LEU A 253
VAL A 261
ALA A 273
GLU A 290
VAL A 303
ILE A 317
GLY A 325
LEU A 374
ASP A 385
 None
 0.69A 4mxyA-2zv7A:
37.2		 4mxyA-2zv7A:
63.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXY_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		9 / 12 LEU A 253
VAL A 261
ALA A 273
GLU A 290
VAL A 303
GLY A 325
LEU A 374
ALA A 384
ASP A 385
 None
 0.57A 4mxyB-2zv7A:
37.7		 4mxyB-2zv7A:
63.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXZ_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		9 / 12 LEU A 253
VAL A 261
ALA A 273
GLU A 290
VAL A 303
ILE A 317
GLY A 325
LEU A 374
ASP A 385
 None
 0.69A 4mxzA-2zv7A:
37.2		 4mxzA-2zv7A:
63.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXZ_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		9 / 12 LEU A 253
VAL A 261
ALA A 273
GLU A 290
VAL A 303
GLY A 325
LEU A 374
ALA A 384
ASP A 385
 None
 0.57A 4mxzB-2zv7A:
37.7		 4mxzB-2zv7A:
63.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OTW_A_DB8A1101_1
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
LYS A 275
VAL A 303
THR A 319
GLY A 325
LEU A 374
ALA A 384
 None
 0.75A 4otwA-2zv7A:
28.8		 4otwA-2zv7A:
31.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_C_MTXC604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 12 ALA A 352
LEU A 497
LEU A 433
LEU A 331
CYH A 381
 None
 1.18A 4q0dC-2zv7A:
undetectable		 4q0dC-2zv7A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_D_MTXD604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 12 ALA A 352
LEU A 497
LEU A 433
LEU A 331
CYH A 381
 None
 1.18A 4q0dD-2zv7A:
undetectable		 4q0dD-2zv7A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		4 / 8 PHE A 490
SER A 428
GLU A 290
ASP A 385
 None
 1.38A 4qb9D-2zv7A:
undetectable		 4qb9D-2zv7A:
19.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R7I_A_STIA1001_1
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
LYS A 275
GLU A 290
MET A 294
THR A 319
ASP A 385
 None
 0.85A 4r7iA-2zv7A:
31.2		 4r7iA-2zv7A:
35.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R7I_A_STIA1001_1
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 VAL A 261
ALA A 273
LYS A 275
THR A 319
LEU A 374
ASP A 385
 None
 0.68A 4r7iA-2zv7A:
31.2		 4r7iA-2zv7A:
35.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RZV_A_032A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 12 ALA A 273
LYS A 275
ILE A 317
THR A 319
SER A 326
 None
 0.62A 4rzvA-2zv7A:
8.0		 4rzvA-2zv7A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RZV_A_032A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 12 ALA A 273
LYS A 275
THR A 319
SER A 326
PHE A 386
 None
 0.94A 4rzvA-2zv7A:
8.0		 4rzvA-2zv7A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RZV_B_032B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 VAL A 261
ALA A 273
LYS A 275
THR A 319
SER A 326
PHE A 386
 None
 0.98A 4rzvB-2zv7A:
26.3		 4rzvB-2zv7A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWP_A_AXIA601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		9 / 12 VAL A 261
ALA A 273
PHE A 321
MET A 322
GLY A 325
ASN A 372
LEU A 374
ALA A 384
ASP A 385
 None
 0.82A 4twpA-2zv7A:
33.5		 4twpA-2zv7A:
46.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWP_B_AXIB601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		9 / 12 LEU A 253
VAL A 261
ALA A 273
PHE A 321
MET A 322
GLY A 325
ASN A 372
LEU A 374
ALA A 384
 None
 0.84A 4twpB-2zv7A:
33.9		 4twpB-2zv7A:
46.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWP_B_AXIB601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		9 / 12 VAL A 261
ALA A 273
PHE A 321
MET A 322
GLY A 325
ASN A 372
LEU A 374
ALA A 384
ASP A 385
 None
 0.76A 4twpB-2zv7A:
33.9		 4twpB-2zv7A:
46.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TYJ_A_0LIA801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 12 ALA A 273
MET A 294
HIS A 365
LEU A 374
ALA A 384
 None
 0.65A 4tyjA-2zv7A:
31.4		 4tyjA-2zv7A:
40.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U5J_A_RXTA601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		9 / 11 LEU A 253
VAL A 261
ALA A 273
MET A 322
GLY A 325
ASN A 372
LEU A 374
ALA A 384
ASP A 385
 None
 0.51A 4u5jA-2zv7A:
37.6		 4u5jA-2zv7A:
64.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U5J_B_RXTB601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 9 LEU A 253
VAL A 261
ALA A 273
MET A 322
GLY A 325
LEU A 374
ASP A 385
 None
 0.44A 4u5jB-2zv7A:
28.8		 4u5jB-2zv7A:
64.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_A_0LIA1772_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
GLU A 290
HIS A 365
ALA A 384
ASP A 385
GLY A 387
 None
 1.41A 4v04A-2zv7A:
30.7		 4v04A-2zv7A:
38.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_B_0LIB1771_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 ALA A 273
GLU A 290
HIS A 365
ALA A 384
ASP A 385
GLY A 387
 None
 1.46A 4v04B-2zv7A:
31.2		 4v04B-2zv7A:
38.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA9_A_AXIA9000_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 11 LEU A 253
ALA A 273
THR A 319
MET A 322
GLY A 325
ASN A 372
LEU A 374
ALA A 384
 None
 0.47A 4wa9A-2zv7A:
29.5		 4wa9A-2zv7A:
45.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA9_B_AXIB9000_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
LYS A 275
THR A 319
PHE A 321
MET A 322
ALA A 384
 None
 0.84A 4wa9B-2zv7A:
32.6		 4wa9B-2zv7A:
45.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA9_B_AXIB9000_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		9 / 12 VAL A 261
ALA A 273
THR A 319
PHE A 321
MET A 322
GLY A 325
ASN A 372
LEU A 374
ALA A 384
 None
 0.81A 4wa9B-2zv7A:
32.6		 4wa9B-2zv7A:
45.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_C_ANWC601_0
(RHODOPSIN KINASE)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		4 / 6 LEU A 253
ALA A 273
MET A 322
LEU A 374
 None
 0.60A 4wboC-2zv7A:
23.6		 4wboC-2zv7A:
18.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WKQ_A_IREA1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 LEU A 253
ALA A 273
LYS A 275
MET A 294
GLY A 325
ASP A 329
LEU A 374
 None
 0.70A 4wkqA-2zv7A:
32.4		 4wkqA-2zv7A:
33.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WKQ_A_IREA1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 LEU A 253
ALA A 273
MET A 294
THR A 319
GLY A 325
ASP A 329
LEU A 374
 None
 0.80A 4wkqA-2zv7A:
32.4		 4wkqA-2zv7A:
33.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XEY_A_1N1A601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		11 / 12 LEU A 253
VAL A 261
ALA A 273
LYS A 275
MET A 294
VAL A 303
THR A 319
PHE A 321
GLY A 325
LEU A 374
ALA A 384
 None
 0.79A 4xeyA-2zv7A:
29.0		 4xeyA-2zv7A:
34.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XEY_A_1N1A601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		11 / 12 LEU A 253
VAL A 261
ALA A 273
LYS A 275
VAL A 303
ILE A 317
THR A 319
PHE A 321
GLY A 325
LEU A 374
ALA A 384
 None
 0.65A 4xeyA-2zv7A:
29.0		 4xeyA-2zv7A:
34.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XEY_B_1N1B601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		9 / 12 LEU A 253
VAL A 261
ALA A 273
LYS A 275
MET A 294
THR A 319
PHE A 321
GLY A 325
ALA A 384
 None
 0.79A 4xeyB-2zv7A:
32.9		 4xeyB-2zv7A:
34.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XEY_B_1N1B601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		11 / 12 LEU A 253
VAL A 261
ALA A 273
LYS A 275
VAL A 303
ILE A 317
THR A 319
PHE A 321
GLY A 325
LEU A 374
ALA A 384
 None
 0.62A 4xeyB-2zv7A:
32.9		 4xeyB-2zv7A:
34.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLI_A_1N1A601_1
(NON-SPECIFIC
PROTEIN-TYROSINE
KINASE)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		10 / 12 LEU A 253
ALA A 273
GLU A 290
MET A 294
VAL A 303
THR A 319
MET A 322
GLY A 325
LEU A 374
ALA A 384
 None
 0.66A 4xliA-2zv7A:
34.6		 4xliA-2zv7A:
46.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLI_B_1N1B600_1
(NON-SPECIFIC
PROTEIN-TYROSINE
KINASE)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		10 / 12 LEU A 253
ALA A 273
GLU A 290
MET A 294
VAL A 303
ILE A 317
THR A 319
GLY A 325
LEU A 374
ALA A 384
 None
 0.60A 4xliB-2zv7A:
29.3		 4xliB-2zv7A:
46.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLI_B_1N1B600_1
(NON-SPECIFIC
PROTEIN-TYROSINE
KINASE)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		9 / 12 LEU A 253
ALA A 273
LYS A 275
GLU A 290
MET A 294
VAL A 303
ILE A 317
THR A 319
ALA A 384
 None
 0.59A 4xliB-2zv7A:
29.3		 4xliB-2zv7A:
46.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		4 / 5 ALA A 411
ARG A 461
ALA A 484
GLU A 482
 None
 1.22A 5a06C-2zv7A:
undetectable
5a06D-2zv7A:
undetectable		 5a06C-2zv7A:
22.35
5a06D-2zv7A:
22.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AAA_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 9 LEU A 253
VAL A 261
ALA A 273
MET A 322
GLY A 325
LEU A 374
ASP A 385
 None
 0.54A 5aaaA-2zv7A:
32.8		 5aaaA-2zv7A:
35.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AAB_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 10 LEU A 253
VAL A 261
ALA A 273
LYS A 275
MET A 322
GLY A 325
LEU A 374
ASP A 385
 None
 0.74A 5aabA-2zv7A:
32.8		 5aabA-2zv7A:
35.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AAC_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 10 LEU A 253
VAL A 261
ALA A 273
LYS A 275
MET A 322
GLY A 325
LEU A 374
ASP A 385
 None
 0.72A 5aacA-2zv7A:
32.5		 5aacA-2zv7A:
35.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_1
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 LEU A 253
GLY A 254
ALA A 273
PHE A 321
GLY A 325
LEU A 374
ALA A 384
 None
 0.82A 5ajqA-2zv7A:
24.2		 5ajqA-2zv7A:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_1
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 LEU A 253
GLY A 254
PHE A 321
GLY A 325
LEU A 374
ALA A 384
ASP A 385
 None
 0.98A 5ajqA-2zv7A:
24.2		 5ajqA-2zv7A:
24.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CSW_B_P06B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 12 VAL A 261
ALA A 273
LYS A 275
THR A 319
PHE A 386
 None
 0.85A 5cswB-2zv7A:
27.1		 5cswB-2zv7A:
34.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		4 / 8 LEU A 497
ILE A 475
PRO A 488
LEU A 493
 None
 0.90A 5g48A-2zv7A:
undetectable		 5g48A-2zv7A:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H2U_A_1N1A501_1
(PROTEIN-TYROSINE
KINASE 6)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 LEU A 253
VAL A 261
ALA A 273
THR A 319
GLY A 325
LEU A 374
 None
 0.43A 5h2uA-2zv7A:
27.0		 5h2uA-2zv7A:
45.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H2U_B_1N1B501_1
(PROTEIN-TYROSINE
KINASE 6)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 LEU A 253
VAL A 261
ALA A 273
ILE A 317
THR A 319
GLY A 325
LEU A 374
 None
 0.50A 5h2uB-2zv7A:
27.2		 5h2uB-2zv7A:
45.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H2U_B_1N1B501_1
(PROTEIN-TYROSINE
KINASE 6)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 VAL A 261
LYS A 275
ILE A 317
THR A 319
GLY A 325
LEU A 374
 None
 0.84A 5h2uB-2zv7A:
27.2		 5h2uB-2zv7A:
45.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H2U_C_1N1C501_1
(PROTEIN-TYROSINE
KINASE 6)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 12 ALA A 273
LYS A 275
THR A 319
GLY A 325
LEU A 374
 None
 0.66A 5h2uC-2zv7A:
31.1		 5h2uC-2zv7A:
45.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H2U_C_1N1C501_1
(PROTEIN-TYROSINE
KINASE 6)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 12 LEU A 253
ALA A 273
ILE A 317
GLY A 325
LEU A 374
 None
 0.53A 5h2uC-2zv7A:
31.1		 5h2uC-2zv7A:
45.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H2U_C_1N1C501_1
(PROTEIN-TYROSINE
KINASE 6)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 12 LEU A 253
ALA A 273
THR A 319
GLY A 325
LEU A 374
 None
 0.49A 5h2uC-2zv7A:
31.1		 5h2uC-2zv7A:
45.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H2U_D_1N1D504_1
(PROTEIN-TYROSINE
KINASE 6)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 LEU A 253
VAL A 261
ALA A 273
ILE A 317
GLY A 325
LEU A 374
 None
 0.43A 5h2uD-2zv7A:
27.3		 5h2uD-2zv7A:
45.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H2U_D_1N1D504_1
(PROTEIN-TYROSINE
KINASE 6)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 LEU A 253
VAL A 261
ALA A 273
THR A 319
GLY A 325
LEU A 374
 None
 0.45A 5h2uD-2zv7A:
27.3		 5h2uD-2zv7A:
45.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_B_032B401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 VAL A 261
ALA A 273
LYS A 275
ILE A 317
THR A 319
PHE A 386
 None
 0.69A 5hesB-2zv7A:
26.8		 5hesB-2zv7A:
25.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HIE_A_P06A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 12 VAL A 261
ALA A 273
LYS A 275
ILE A 317
THR A 319
 None
 0.52A 5hieA-2zv7A:
26.5		 5hieA-2zv7A:
33.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HIE_B_P06B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 12 VAL A 261
ALA A 273
LYS A 275
ILE A 317
THR A 319
 None
 0.54A 5hieB-2zv7A:
26.4		 5hieB-2zv7A:
33.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HIE_D_P06D801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 12 VAL A 261
ALA A 273
LYS A 275
ILE A 317
THR A 319
 None
 0.52A 5hieD-2zv7A:
26.3		 5hieD-2zv7A:
33.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I9X_A_DB8A1001_1
(EPHRIN TYPE-A
RECEPTOR 2)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 ALA A 273
GLU A 290
ILE A 317
THR A 319
GLY A 325
LEU A 374
 None
 0.50A 5i9xA-2zv7A:
27.4		 5i9xA-2zv7A:
40.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I9Y_A_1N1A1001_1
(EPHRIN TYPE-A
RECEPTOR 2)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 ALA A 273
LYS A 275
GLU A 290
MET A 294
THR A 319
GLY A 325
LEU A 374
 None
 0.60A 5i9yA-2zv7A:
27.4		 5i9yA-2zv7A:
40.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZJ_F_AZ1F2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAR-DAR-DAR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		4 / 7 GLY A 254
GLY A 256
GLY A 259
VAL A 261
 None
 0.34A 5izjB-2zv7A:
24.1		 5izjB-2zv7A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MO4_A_NILA601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 10 LEU A 253
VAL A 261
ILE A 317
PHE A 321
MET A 322
GLY A 325
 None
 0.95A 5mo4A-2zv7A:
26.5		 5mo4A-2zv7A:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MO4_A_NILA601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 10 LEU A 253
VAL A 261
LYS A 275
GLU A 290
ILE A 317
 None
 0.63A 5mo4A-2zv7A:
26.5		 5mo4A-2zv7A:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MO4_A_NILA601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 ALA A 273
LEU A 302
VAL A 303
HIS A 365
LEU A 374
ALA A 384
 None
 0.58A 5mo4A-2zv7A:
26.5		 5mo4A-2zv7A:
28.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5P9I_A_1E8A701_1
(TYROSINE-PROTEIN
KINASE BTK)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 VAL A 261
ALA A 273
LYS A 275
ILE A 317
THR A 319
GLY A 325
LEU A 374
PHE A 386
 None
 0.87A 5p9iA-2zv7A:
32.2		 5p9iA-2zv7A:
41.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE0_A_XINA401_1
(AP2-ASSOCIATED
PROTEIN KINASE 1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 ALA A 273
MET A 294
VAL A 303
PHE A 321
GLY A 325
LEU A 374
 None
 0.77A 5te0A-2zv7A:
25.0		 5te0A-2zv7A:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCV_A_1N1A404_1
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 LEU A 253
ALA A 273
LYS A 275
GLU A 290
VAL A 303
THR A 319
 None
 0.93A 5vcvA-2zv7A:
25.7		 5vcvA-2zv7A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_1
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 LEU A 253
VAL A 261
ALA A 273
LYS A 275
GLU A 290
THR A 319
 None
 0.80A 5vcyA-2zv7A:
25.4		 5vcyA-2zv7A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_1
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 12 LEU A 253
GLY A 254
VAL A 261
GLY A 325
ALA A 384
 None
 0.72A 5xv7A-2zv7A:
23.6		 5xv7A-2zv7A:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YU9_C_1E8C1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 12 VAL A 261
ALA A 273
LYS A 275
GLY A 325
ASP A 329
 None
 0.73A 5yu9C-2zv7A:
25.2		 5yu9C-2zv7A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YU9_D_1E8D1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 VAL A 261
ALA A 273
LYS A 275
GLY A 325
ASP A 329
LEU A 374
 None
 0.80A 5yu9D-2zv7A:
25.9		 5yu9D-2zv7A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_B_LEVB801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		6 / 12 LEU A 253
VAL A 261
ALA A 273
LYS A 275
GLU A 290
MET A 294
 None
 0.64A 5zv2B-2zv7A:
30.7		 5zv2B-2zv7A:
15.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FNM_A_1N1A1001_1
(-)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		10 / 12 VAL A 261
ALA A 273
LYS A 275
GLU A 290
MET A 294
ILE A 317
THR A 319
MET A 322
GLY A 325
LEU A 374
 None
 0.53A 6fnmA-2zv7A:
33.8		 6fnmA-2zv7A:
39.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
GLU A 290
MET A 294
VAL A 303
THR A 319
ASP A 385
 None
 1.06A 6hd4A-2zv7A:
30.8		 6hd4A-2zv7A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
GLU A 290
VAL A 303
ILE A 317
THR A 319
ASP A 385
 None
 0.87A 6hd4A-2zv7A:
30.8		 6hd4A-2zv7A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
MET A 294
VAL A 303
THR A 319
ALA A 384
ASP A 385
 None
 1.08A 6hd4A-2zv7A:
30.8		 6hd4A-2zv7A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
MET A 294
VAL A 303
THR A 319
LEU A 374
ALA A 384
 None
 1.11A 6hd4A-2zv7A:
30.8		 6hd4A-2zv7A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
VAL A 303
ILE A 317
THR A 319
ALA A 384
ASP A 385
 None
 0.70A 6hd4A-2zv7A:
30.8		 6hd4A-2zv7A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
VAL A 303
ILE A 317
THR A 319
LEU A 374
ALA A 384
 None
 0.86A 6hd4A-2zv7A:
30.8		 6hd4A-2zv7A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
GLU A 290
MET A 294
VAL A 303
THR A 319
ASP A 385
 None
 1.08A 6hd4B-2zv7A:
31.0		 6hd4B-2zv7A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
GLU A 290
VAL A 303
ILE A 317
THR A 319
ASP A 385
 None
 0.88A 6hd4B-2zv7A:
31.0		 6hd4B-2zv7A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
MET A 294
VAL A 303
THR A 319
ALA A 384
ASP A 385
 None
 1.09A 6hd4B-2zv7A:
31.0		 6hd4B-2zv7A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
MET A 294
VAL A 303
THR A 319
LEU A 374
ALA A 384
 None
 1.09A 6hd4B-2zv7A:
31.0		 6hd4B-2zv7A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
VAL A 303
ILE A 317
THR A 319
ALA A 384
ASP A 385
 None
 0.70A 6hd4B-2zv7A:
31.0		 6hd4B-2zv7A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		7 / 12 VAL A 261
ALA A 273
VAL A 303
ILE A 317
THR A 319
LEU A 374
ALA A 384
 None
 0.82A 6hd4B-2zv7A:
31.0		 6hd4B-2zv7A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		4 / 6 LEU A 253
PHE A 321
MET A 322
GLY A 325
 None
 0.76A 6hd4B-2zv7A:
31.0		 6hd4B-2zv7A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 VAL A 261
ALA A 273
GLU A 290
MET A 294
VAL A 303
THR A 319
PHE A 321
ASP A 385
 None
 1.02A 6hd6A-2zv7A:
25.4		 6hd6A-2zv7A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 VAL A 261
ALA A 273
GLU A 290
VAL A 303
ILE A 317
THR A 319
PHE A 321
ASP A 385
 None
 0.83A 6hd6A-2zv7A:
25.4		 6hd6A-2zv7A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 VAL A 261
ALA A 273
MET A 294
VAL A 303
THR A 319
PHE A 321
ALA A 384
ASP A 385
 None
 1.02A 6hd6A-2zv7A:
25.4		 6hd6A-2zv7A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 VAL A 261
ALA A 273
MET A 294
VAL A 303
THR A 319
PHE A 321
LEU A 374
ALA A 384
 None
 1.08A 6hd6A-2zv7A:
25.4		 6hd6A-2zv7A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 VAL A 261
ALA A 273
VAL A 303
ILE A 317
THR A 319
PHE A 321
ALA A 384
ASP A 385
 None
 0.68A 6hd6A-2zv7A:
25.4		 6hd6A-2zv7A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 VAL A 261
ALA A 273
VAL A 303
ILE A 317
THR A 319
PHE A 321
LEU A 374
ALA A 384
 None
 0.84A 6hd6A-2zv7A:
25.4		 6hd6A-2zv7A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_B_STIB601_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		9 / 12 LEU A 253
VAL A 261
ALA A 273
GLU A 290
MET A 294
VAL A 303
THR A 319
PHE A 321
ASP A 385
 None
 1.07A 6hd6B-2zv7A:
30.9		 6hd6B-2zv7A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_B_STIB601_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
ALA A 273
LYS A 275
GLU A 290
MET A 294
VAL A 303
PHE A 321
 None
 0.89A 6hd6B-2zv7A:
30.9		 6hd6B-2zv7A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_B_STIB601_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		8 / 12 LEU A 253
VAL A 261
ALA A 273
MET A 294
VAL A 303
THR A 319
PHE A 321
LEU A 374
 None
 1.18A 6hd6B-2zv7A:
30.9		 6hd6B-2zv7A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_B_STIB601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2zv7 TYROSINE-PROTEIN
KINASE LYN
(Mus
musculus) 		5 / 7 ILE A 317
MET A 322
GLY A 325
ARG A 366
ALA A 384
 None
 0.96A 6hd6B-2zv7A:
30.9		 6hd6B-2zv7A:
19.81