SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zvf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FDU_B_ESTB354_1 (17-BETA-HYDROXYSTERO ID DEHYDROGENASE)	2zvf	ALANYL-TRNA SYNTHETASE (Archaeoglobus fulgidus)	4 / 8	VAL A 896 LEU A 888 MET A 839 VAL A 846	None	1.04A	1fduB-2zvfA: undetectable	1fduB-2zvfA: 20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1N4H_A_REAA500_1 (NUCLEAR RECEPTOR ROR-BETA)	2zvf	ALANYL-TRNA SYNTHETASE (Archaeoglobus fulgidus)	5 / 11	GLN A 886 ILE A 865 ALA A 869 VAL A 884 VAL A 814	None	1.25A	1n4hA-2zvfA: undetectable	1n4hA-2zvfA: 21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C12_F_SPMF1433_1 (NITROALKANE OXIDASE)	2zvf	ALANYL-TRNA SYNTHETASE (Archaeoglobus fulgidus)	5 / 11	LEU A 838 GLU A 813 ALA A 802 LEU A 798 ASP A 796	None	1.32A	2c12F-2zvfA: undetectable	2c12F-2zvfA: 17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_G_SVRG506_1 (PHOSPHOLIPASE A2)	2zvf	ALANYL-TRNA SYNTHETASE (Archaeoglobus fulgidus)	4 / 8	VAL A 810 VAL A 811 GLY A 836 LYS A 832	None	0.97A	3bjwA-2zvfA: undetectable	3bjwA-2zvfA: 16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NWV_A_ACAA18_2 (SCRFP-TAG,GP41)	2zvf	ALANYL-TRNA SYNTHETASE (Archaeoglobus fulgidus)	4 / 7	ASP A 792 TRP A 794 ALA A 791 LEU A 825	None	0.99A	5nwvA-2zvfA: undetectable	5nwvA-2zvfA: 12.50

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FDU_B_ESTB354_1","17-BETA-HYDROXYSTEROID DEHYDROGENASE","2zvf","ALANYL-TRNA SYNTHETASE","Archaeoglobus fulgidus",4,"VAL A 896;LEU A 888;MET A 839;VAL A 846","None","1.04A","1fduB-2zvfA:undetectable","1fduB-2zvfA:20.60"],["1N4H_A_REAA500_1","NUCLEAR RECEPTOR ROR-BETA","2zvf","ALANYL-TRNA SYNTHETASE","Archaeoglobus fulgidus",5,"GLN A 886;ILE A 865;ALA A 869;VAL A 884;VAL A 814","None","1.25A","1n4hA-2zvfA:undetectable","1n4hA-2zvfA:21.32"],["2C12_F_SPMF1433_1","NITROALKANE OXIDASE","2zvf","ALANYL-TRNA SYNTHETASE","Archaeoglobus fulgidus",5,"LEU A 838;GLU A 813;ALA A 802;LEU A 798;ASP A 796","None","1.32A","2c12F-2zvfA:undetectable","2c12F-2zvfA:17.55"],["3BJW_G_SVRG506_1","PHOSPHOLIPASE A2;PHOSPHOLIPASE A2","2zvf","ALANYL-TRNA SYNTHETASE","Archaeoglobus fulgidus",4,"VAL A 810;VAL A 811;GLY A 836;LYS A 832","None","0.97A","3bjwA-2zvfA:undetectable","3bjwA-2zvfA:16.48"],["5NWV_A_ACAA18_2","SCRFP-TAG,GP41","2zvf","ALANYL-TRNA SYNTHETASE","Archaeoglobus fulgidus",4,"ASP A 792;TRP A 794;ALA A 791;LEU A 825","None","0.99A","5nwvA-2zvfA:undetectable","5nwvA-2zvfA:12.50"]]