SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zvw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 2zvw PROLIFERATING CELL
NUCLEAR ANTIGEN 2
(Arabidopsis
thaliana) 		4 / 8 ILE A 121
ASN A  74
MET A 119
LEU A  37
 None
 0.98A 1dzmA-2zvwA:
undetectable		 1dzmA-2zvwA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 2zvw PROLIFERATING CELL
NUCLEAR ANTIGEN 2
(Arabidopsis
thaliana) 		4 / 7 PHE A 144
VAL A 158
VAL A 235
ILE A 227
 None
 0.97A 1p7rA-2zvwA:
undetectable		 1p7rA-2zvwA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_A_SALA710_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 2zvw PROLIFERATING CELL
NUCLEAR ANTIGEN 2
(Arabidopsis
thaliana) 		4 / 7 VAL A  19
LEU A  22
ALA A  39
LEU A  37
 None
 0.76A 1pthA-2zvwA:
undetectable		 1pthA-2zvwA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 2zvw PROLIFERATING CELL
NUCLEAR ANTIGEN 2
(Arabidopsis
thaliana) 		4 / 7 VAL A  19
LEU A  22
ALA A  39
LEU A  37
 None
 0.76A 1pthB-2zvwA:
undetectable		 1pthB-2zvwA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2zvw PROLIFERATING CELL
NUCLEAR ANTIGEN 2
(Arabidopsis
thaliana) 		5 / 11 THR A 224
PHE A 144
LEU A 182
VAL A 167
PHE A 169
 None
 1.44A 1q23G-2zvwA:
undetectable		 1q23G-2zvwA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2zvw PROLIFERATING CELL
NUCLEAR ANTIGEN 2
(Arabidopsis
thaliana) 		5 / 11 THR A 224
PHE A 215
PHE A 144
VAL A 167
PHE A 169
 None
 1.46A 1q23G-2zvwA:
undetectable		 1q23G-2zvwA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)		 2zvw PROLIFERATING CELL
NUCLEAR ANTIGEN 2
(Arabidopsis
thaliana) 		5 / 12 THR A  89
LEU A   4
ILE A  90
VAL A  99
LEU A  52
 None
 1.36A 1wsvB-2zvwA:
undetectable		 1wsvB-2zvwA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_2
(ANDROGEN RECEPTOR)		 2zvw PROLIFERATING CELL
NUCLEAR ANTIGEN 2
(Arabidopsis
thaliana) 		4 / 6 LEU A   4
MET A  75
MET A  78
LEU A  16
 None
 1.42A 2oz7A-2zvwA:
undetectable		 2oz7A-2zvwA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2zvw PROLIFERATING CELL
NUCLEAR ANTIGEN 2
(Arabidopsis
thaliana) 		5 / 12 LEU A  79
LEU A  16
LEU A  72
ILE A  88
VAL A  99
 None
 1.06A 2pnjA-2zvwA:
undetectable		 2pnjA-2zvwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 2zvw PROLIFERATING CELL
NUCLEAR ANTIGEN 2
(Arabidopsis
thaliana) 		4 / 7 VAL A 236
TYR A 250
ILE A 128
ASP A 130
 None
 1.13A 2x45B-2zvwA:
undetectable		 2x45B-2zvwA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 2zvw PROLIFERATING CELL
NUCLEAR ANTIGEN 2
(Arabidopsis
thaliana) 		4 / 7 VAL A 236
TYR A 250
ILE A 128
ASP A 130
 None
 1.13A 2x45C-2zvwA:
undetectable		 2x45C-2zvwA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)		 2zvw PROLIFERATING CELL
NUCLEAR ANTIGEN 2
(Arabidopsis
thaliana) 		4 / 7 VAL A 236
TYR A 250
ILE A 128
ASP A 130
 None
 1.05A 3bu1A-2zvwA:
undetectable		 3bu1A-2zvwA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3003_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2zvw PROLIFERATING CELL
NUCLEAR ANTIGEN 2
(Arabidopsis
thaliana) 		4 / 6 ILE A 247
VAL A  19
LEU A  16
LEU A  12
 None
 0.92A 3kp6A-2zvwA:
undetectable
3kp6B-2zvwA:
undetectable		 3kp6A-2zvwA:
19.71
3kp6B-2zvwA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 2zvw PROLIFERATING CELL
NUCLEAR ANTIGEN 2
(Arabidopsis
thaliana) 		3 / 3 THR A 186
ASP A 189
GLU A 192
 None
 0.85A 3qowA-2zvwA:
undetectable		 3qowA-2zvwA:
23.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VKX_A_T3A301_1
(PROLIFERATING CELL
NUCLEAR ANTIGEN)		 2zvw PROLIFERATING CELL
NUCLEAR ANTIGEN 2
(Arabidopsis
thaliana) 		4 / 6 MET A  40
LEU A  47
PRO A 234
TYR A 250
 None
 0.51A 3vkxA-2zvwA:
36.4		 3vkxA-2zvwA:
61.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2zvw PROLIFERATING CELL
NUCLEAR ANTIGEN 2
(Arabidopsis
thaliana) 		5 / 12 LEU A  79
LEU A  16
LEU A  72
ILE A  88
VAL A  99
 None
 1.19A 4f4dA-2zvwA:
undetectable		 4f4dA-2zvwA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2zvw PROLIFERATING CELL
NUCLEAR ANTIGEN 2
(Arabidopsis
thaliana) 		5 / 12 LEU A  79
LEU A  16
LEU A  72
ILE A  88
VAL A  99
 None
 0.98A 4f4dB-2zvwA:
undetectable		 4f4dB-2zvwA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)		 2zvw PROLIFERATING CELL
NUCLEAR ANTIGEN 2
(Arabidopsis
thaliana) 		3 / 3 PHE A 144
TYR A 249
TYR A 239
 None
 1.08A 4ffwA-2zvwA:
undetectable		 4ffwA-2zvwA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2zvw PROLIFERATING CELL
NUCLEAR ANTIGEN 2
(Arabidopsis
thaliana) 		5 / 10 LEU A  79
LEU A  16
LEU A  72
ILE A  88
VAL A  99
 None
 1.16A 4mk4A-2zvwA:
undetectable		 4mk4A-2zvwA:
20.05