SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zvy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_1
(POL POLYPROTEIN)		 2zvy CHEMOTAXIS PROTEIN
MOTB
(Salmonella
enterica) 		5 / 12 LEU A 193
VAL A 265
ILE A 187
GLY A 186
ILE A 191
 None
 0.89A 2avvD-2zvyA:
undetectable		 2avvD-2zvyA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		 2zvy CHEMOTAXIS PROTEIN
MOTB
(Salmonella
enterica) 		4 / 6 LEU A 149
LEU A 144
ILE A 151
ARG A 150
 None
 1.00A 2rlfA-2zvyA:
undetectable
2rlfB-2zvyA:
undetectable		 2rlfA-2zvyA:
13.77
2rlfB-2zvyA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		 2zvy CHEMOTAXIS PROTEIN
MOTB
(Salmonella
enterica) 		4 / 6 LEU A 149
LEU A 144
ILE A 151
ARG A 150
 None
 1.06A 2rlfB-2zvyA:
undetectable
2rlfC-2zvyA:
undetectable		 2rlfB-2zvyA:
13.77
2rlfC-2zvyA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		 2zvy CHEMOTAXIS PROTEIN
MOTB
(Salmonella
enterica) 		4 / 6 LEU A 149
LEU A 144
ILE A 151
ARG A 150
 None
 0.93A 2rlfC-2zvyA:
undetectable
2rlfD-2zvyA:
undetectable		 2rlfC-2zvyA:
13.77
2rlfD-2zvyA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_C_VDYC6178_1
(VITAMIN D
HYDROXYLASE)		 2zvy CHEMOTAXIS PROTEIN
MOTB
(Salmonella
enterica) 		5 / 12 ILE A 151
LEU A 140
MET A 161
ILE A 261
LEU A 226
 None
 1.20A 3a51C-2zvyA:
undetectable		 3a51C-2zvyA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_2
(DIHYDROFOLATE
REDUCTASE)		 2zvy CHEMOTAXIS PROTEIN
MOTB
(Salmonella
enterica) 		3 / 3 ARG A 174
ILE A 153
THR A 197
 None
 0.55A 3ia4D-2zvyA:
undetectable		 3ia4D-2zvyA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_2
(FIV PROTEASE)		 2zvy CHEMOTAXIS PROTEIN
MOTB
(Salmonella
enterica) 		5 / 10 ALA A 181
GLY A 186
ILE A 187
VAL A 236
LEU A 231
 None
 0.94A 3ogpB-2zvyA:
undetectable		 3ogpB-2zvyA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RV6_A_RPBA1103_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		 2zvy CHEMOTAXIS PROTEIN
MOTB
(Salmonella
enterica) 		5 / 11 GLN A 157
HIS A 196
GLY A 195
ALA A 243
SER A 215
 None
 1.31A 4rv6A-2zvyA:
undetectable		 4rv6A-2zvyA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RV6_B_RPBB1103_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		 2zvy CHEMOTAXIS PROTEIN
MOTB
(Salmonella
enterica) 		5 / 11 GLN A 157
HIS A 196
GLY A 195
ALA A 243
SER A 215
 None
 1.32A 4rv6B-2zvyA:
undetectable		 4rv6B-2zvyA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 2zvy CHEMOTAXIS PROTEIN
MOTB
(Salmonella
enterica) 		6 / 12 LEU A 123
ALA A 179
ASP A 175
ILE A 176
ILE A 151
ILE A 180
 None
 1.49A 5e5jB-2zvyA:
undetectable		 5e5jB-2zvyA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)		 2zvy CHEMOTAXIS PROTEIN
MOTB
(Salmonella
enterica) 		3 / 3 HIS A 280
HIS A 277
HIS A 278
 None
 0.97A 5oexA-2zvyA:
undetectable		 5oexA-2zvyA:
16.38