SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zws'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 7 GLY A 463
GLY A 462
GLN A 371
TYR A 455
 None
 0.96A 1ekjE-2zwsA:
undetectable
1ekjF-2zwsA:
undetectable		 1ekjE-2zwsA:
17.00
1ekjF-2zwsA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 8 SER A 464
ILE A 326
GLU A 459
ARG A 160
 None
None
None
ZN  A 647 ( 4.3A)
 0.87A 1meiA-2zwsA:
undetectable		 1meiA-2zwsA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_C_SAMC200_0
(METHIONINE REPRESSOR)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 435
GLY A 149
GLU A 290
ARG A 145
LEU A 292
 None
 1.28A 1mjoC-2zwsA:
undetectable
1mjoD-2zwsA:
undetectable		 1mjoC-2zwsA:
9.60
1mjoD-2zwsA:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		5 / 9 ILE A  14
GLY A  16
ALA A  12
GLU A 556
ARG A 132
 None
 1.29A 1mrgA-2zwsA:
undetectable		 1mrgA-2zwsA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_2
(ANGIOTENSIN
CONVERTING ENZYME)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 4 SER A 594
VAL A 512
PHE A 523
VAL A 545
 None
 1.33A 1o86A-2zwsA:
undetectable		 1o86A-2zwsA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 6 ARG A 132
ASP A 579
TYR A 586
GLU A 556
 None
 0.94A 1rjdA-2zwsA:
undetectable		 1rjdA-2zwsA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 6 ARG A 132
ASP A 579
TYR A 586
GLU A 556
 None
 0.92A 1rjdB-2zwsA:
undetectable		 1rjdB-2zwsA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 6 ARG A 132
ASP A 579
TYR A 586
GLU A 556
 None
 0.96A 1rjdC-2zwsA:
undetectable		 1rjdC-2zwsA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 7 TYR A 460
THR A 380
THR A 389
SER A 447
 GOL  A 656 (-4.5A)
None
None
None
 1.20A 1tv8A-2zwsA:
undetectable		 1tv8A-2zwsA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A  97
HIS A  99
HIS A 204
 ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
ZN  A 647 (-3.3A)
 0.72A 1w2zC-2zwsA:
undetectable		 1w2zC-2zwsA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A  97
HIS A  99
HIS A 204
 ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
ZN  A 647 (-3.3A)
 0.70A 1w2zD-2zwsA:
undetectable		 1w2zD-2zwsA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		5 / 10 ARG A 160
TYR A 445
MET A  24
GLY A  64
TYR A 460
 ZN  A 647 ( 4.3A)
None
GOL  A 656 (-4.7A)
None
GOL  A 656 (-4.5A)
 1.47A 2coiA-2zwsA:
undetectable
2coiB-2zwsA:
undetectable		 2coiA-2zwsA:
21.26
2coiB-2zwsA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 204
HIS A  97
HIS A  99
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
 0.75A 2dysA-2zwsA:
undetectable		 2dysA-2zwsA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 204
HIS A  97
HIS A  99
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
 0.75A 2dysN-2zwsA:
undetectable		 2dysN-2zwsA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 204
HIS A  97
HIS A  99
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
 0.73A 2eikA-2zwsA:
undetectable		 2eikA-2zwsA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 204
HIS A  97
HIS A  99
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
 0.76A 2eikN-2zwsA:
undetectable		 2eikN-2zwsA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 204
HIS A  97
HIS A  99
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
 0.75A 2eilA-2zwsA:
undetectable		 2eilA-2zwsA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 204
HIS A  97
HIS A  99
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
 0.72A 2eimN-2zwsA:
undetectable		 2eimN-2zwsA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 204
HIS A  97
HIS A  99
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
 0.72A 2einA-2zwsA:
undetectable		 2einA-2zwsA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 204
HIS A  97
HIS A  99
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
 0.69A 2einN-2zwsA:
undetectable		 2einN-2zwsA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 7 THR A 380
ALA A 410
TYR A 475
LEU A 393
 None
 1.00A 2hzqA-2zwsA:
undetectable		 2hzqA-2zwsA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A  97
HIS A  99
HIS A 204
 ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
ZN  A 647 (-3.3A)
 0.70A 2oqeA-2zwsA:
undetectable		 2oqeA-2zwsA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A  97
HIS A  99
HIS A 204
 ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
ZN  A 647 (-3.3A)
 0.69A 2oqeB-2zwsA:
undetectable		 2oqeB-2zwsA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A  97
HIS A  99
HIS A 204
 ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
ZN  A 647 (-3.3A)
 0.71A 2oqeC-2zwsA:
undetectable		 2oqeC-2zwsA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A  97
HIS A  99
HIS A 204
 ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
ZN  A 647 (-3.3A)
 0.69A 2oqeD-2zwsA:
undetectable		 2oqeD-2zwsA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A  97
HIS A  99
HIS A 204
 ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
ZN  A 647 (-3.3A)
 0.71A 2oqeF-2zwsA:
undetectable		 2oqeF-2zwsA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A  97
HIS A  99
HIS A 204
 ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
ZN  A 647 (-3.3A)
 0.72A 2w0qB-2zwsA:
undetectable		 2w0qB-2zwsA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 7 LEU A 486
GLU A 404
ALA A  44
ILE A 134
 None
 0.83A 2xkwA-2zwsA:
undetectable		 2xkwA-2zwsA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 204
HIS A  97
HIS A  99
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
 0.74A 3abkN-2zwsA:
undetectable		 3abkN-2zwsA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 204
HIS A  97
HIS A  99
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
 0.78A 3ablN-2zwsA:
undetectable		 3ablN-2zwsA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 204
HIS A  97
HIS A  99
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
 0.74A 3ag2N-2zwsA:
undetectable		 3ag2N-2zwsA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 204
HIS A  97
HIS A  99
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
 0.75A 3ag3A-2zwsA:
undetectable		 3ag3A-2zwsA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 204
HIS A  97
HIS A  99
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
 0.76A 3ag3N-2zwsA:
undetectable		 3ag3N-2zwsA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 204
HIS A  97
HIS A  99
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
 0.75A 3ag4N-2zwsA:
undetectable		 3ag4N-2zwsA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOB_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		5 / 12 MET A 182
PHE A 241
ASN A 439
GLY A 440
LEU A 405
 None
 1.39A 3aobC-2zwsA:
undetectable		 3aobC-2zwsA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 204
HIS A  97
HIS A  99
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
 0.76A 3asnA-2zwsA:
undetectable		 3asnA-2zwsA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 204
HIS A  97
HIS A  99
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
 0.75A 3asoN-2zwsA:
undetectable		 3asoN-2zwsA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 462
GLY A 463
GLY A 327
ILE A 376
 None
 0.69A 3d41A-2zwsA:
undetectable		 3d41A-2zwsA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_CUA801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A  97
HIS A  99
HIS A 204
 ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
ZN  A 647 (-3.3A)
 0.72A 3hiiA-2zwsA:
undetectable		 3hiiA-2zwsA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_CUB801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A  97
HIS A  99
HIS A 204
 ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
ZN  A 647 (-3.3A)
 0.73A 3hiiB-2zwsA:
undetectable		 3hiiB-2zwsA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH201_1
(PROTEIN S100-A4)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		5 / 9 ILE A 400
PHE A 147
PHE A 187
GLY A   8
PHE A   7
 None
 1.49A 3ko0H-2zwsA:
undetectable
3ko0I-2zwsA:
undetectable		 3ko0H-2zwsA:
9.49
3ko0I-2zwsA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ201_1
(PROTEIN S100-A4)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		5 / 8 PHE A 187
GLY A   8
PHE A   7
ILE A 400
PHE A 147
 None
 1.48A 3ko0O-2zwsA:
undetectable
3ko0Q-2zwsA:
undetectable		 3ko0O-2zwsA:
9.49
3ko0Q-2zwsA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR201_1
(PROTEIN S100-A4)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		5 / 10 ILE A 400
PHE A 147
PHE A 187
GLY A   8
PHE A   7
 None
 1.49A 3ko0R-2zwsA:
undetectable
3ko0T-2zwsA:
undetectable		 3ko0R-2zwsA:
9.49
3ko0T-2zwsA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 PHE A 201
SER A 199
GLN A 276
 None
 0.97A 3smtA-2zwsA:
undetectable		 3smtA-2zwsA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA2_1
(CYTOCHROME P450 2D6)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		5 / 11 LEU A 560
THR A 558
VAL A 574
THR A 575
PHE A 639
 None
 1.23A 3tbgA-2zwsA:
undetectable		 3tbgA-2zwsA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC2_1
(CYTOCHROME P450 2D6)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		5 / 10 LEU A 560
THR A 558
VAL A 574
THR A 575
PHE A 639
 None
 1.19A 3tbgC-2zwsA:
undetectable		 3tbgC-2zwsA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_0
(GLYCINE
N-METHYLTRANSFERASE)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 6 SER A 601
LEU A 560
HIS A 617
ARG A 587
 None
 1.31A 3thrB-2zwsA:
undetectable		 3thrB-2zwsA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 7 ILE A 519
GLY A 524
ALA A 595
GLN A 529
 None
 0.85A 4g0uB-2zwsA:
undetectable		 4g0uB-2zwsA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_ACTA303_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 TYR A 460
HIS A 204
ARG A 160
 GOL  A 656 (-4.5A)
ZN  A 647 (-3.3A)
ZN  A 647 ( 4.3A)
 0.93A 4htfA-2zwsA:
undetectable		 4htfA-2zwsA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 5 PRO A 169
ASP A 170
ASN A 168
VAL A 414
 None
 1.39A 4hytA-2zwsA:
undetectable		 4hytA-2zwsA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 ASP A 218
ARG A 160
THR A 269
 None
ZN  A 647 ( 4.3A)
None
 0.73A 4i13A-2zwsA:
undetectable		 4i13A-2zwsA:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 ASP A 218
ARG A 160
THR A 269
 None
ZN  A 647 ( 4.3A)
None
 0.71A 4p3rA-2zwsA:
undetectable		 4p3rA-2zwsA:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAH_A_LNRA600_1
(PHENYLALANINE
HYDROXYLASE)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 6 HIS A 204
HIS A  97
TYR A 445
GLU A 411
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
None
ZN  A 647 (-2.0A)
 0.92A 4pahA-2zwsA:
undetectable		 4pahA-2zwsA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		5 / 9 ILE A  14
GLY A  16
ALA A  12
GLU A 556
ARG A 132
 None
 1.38A 4yp2B-2zwsA:
undetectable		 4yp2B-2zwsA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		5 / 9 ILE A  14
GLY A  16
ALA A  12
GLU A 556
ARG A 132
 None
 1.36A 5cf9B-2zwsA:
undetectable		 5cf9B-2zwsA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 ALA A 109
ASN A 112
LEU A 113
 GOL  A 655 (-3.7A)
None
None
 0.44A 5i1nC-2zwsA:
undetectable		 5i1nC-2zwsA:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 ALA A 109
ASN A 112
LEU A 113
 GOL  A 655 (-3.7A)
None
None
 0.42A 5i1oC-2zwsA:
undetectable		 5i1oC-2zwsA:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 ALA A 109
ASN A 112
LEU A 113
 GOL  A 655 (-3.7A)
None
None
 0.43A 5i1pD-2zwsA:
undetectable		 5i1pD-2zwsA:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		5 / 12 PHE A 123
LEU A  93
ILE A 134
ALA A  76
LEU A  78
 None
 1.25A 5ienA-2zwsA:
undetectable		 5ienA-2zwsA:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 4 ASN A 245
ILE A  66
TYR A 445
PHE A 304
 None
 1.37A 5igvA-2zwsA:
undetectable		 5igvA-2zwsA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 GLY A 151
GLN A 288
LYS A 279
 None
None
GOL  A 657 (-2.9A)
 0.79A 5imsB-2zwsA:
undetectable		 5imsB-2zwsA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_1
(PAVINE
N-METHYLTRANSFERASE)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 5 PHE A 187
SER A 186
GLN A 142
ASP A   2
 None
GOL  A 668 ( 4.9A)
None
None
 1.50A 5kpcA-2zwsA:
undetectable		 5kpcA-2zwsA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PAH_A_LDPA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 4 HIS A 204
HIS A  97
TYR A 445
GLU A 411
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
None
ZN  A 647 (-2.0A)
 0.92A 5pahA-2zwsA:
undetectable		 5pahA-2zwsA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 8 ARG A  55
GLY A   8
GLN A 138
LEU A 141
 None
None
None
GOL  A 654 (-4.0A)
 0.78A 5sxqB-2zwsA:
undetectable		 5sxqB-2zwsA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 8 ARG A  55
GLY A   8
GLN A 138
LEU A 141
 None
None
None
GOL  A 654 (-4.0A)
 0.81A 5syjA-2zwsA:
undetectable		 5syjA-2zwsA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 204
HIS A  97
HIS A  99
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
 0.73A 5w97a-2zwsA:
undetectable		 5w97a-2zwsA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 204
HIS A  97
HIS A  99
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
 0.73A 5x1fA-2zwsA:
undetectable		 5x1fA-2zwsA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA503_1
(CYTOCHROME P450 2C9)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 5 PRO A 387
GLY A 381
THR A 380
ASN A 382
 None
 0.84A 5x23A-2zwsA:
undetectable		 5x23A-2zwsA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA503_1
(CYTOCHROME P450 2C9)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 6 PRO A 387
GLY A 381
THR A 380
ASN A 382
 None
 0.90A 5x24A-2zwsA:
undetectable		 5x24A-2zwsA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Z_A_BHAA201_0
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 6 LEU A  78
VAL A  91
LEU A  93
VAL A  57
 None
 0.95A 5x7zA-2zwsA:
undetectable		 5x7zA-2zwsA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA502_1
(CYTOCHROME P450 2C9)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 6 PRO A 387
GLY A 381
THR A 380
ASN A 382
 None
 1.00A 5xxiA-2zwsA:
undetectable		 5xxiA-2zwsA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 204
HIS A  97
HIS A  99
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
 0.78A 5z84A-2zwsA:
undetectable		 5z84A-2zwsA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 204
HIS A  97
HIS A  99
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
 0.79A 5z85A-2zwsA:
undetectable		 5z85A-2zwsA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 204
HIS A  97
HIS A  99
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
 0.76A 5zcoA-2zwsA:
undetectable		 5zcoA-2zwsA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_2
(RIFAMPIN
MONOOXYGENASE)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 6 GLN A 396
VAL A 302
LEU A 405
ARG A 421
 None
 1.33A 6brdB-2zwsA:
undetectable		 6brdB-2zwsA:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_1
(NS3 PROTEASE)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		5 / 9 HIS A  37
ARG A  39
ALA A  12
SER A 133
ASP A  13
 GOL  A 659 ( 4.5A)
None
None
None
None
 1.41A 6c2mA-2zwsA:
undetectable		 6c2mA-2zwsA:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 5 LEU A 466
THR A 389
THR A 323
GLY A 381
 None
 1.16A 6gtqA-2zwsA:
undetectable		 6gtqA-2zwsA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_1
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 5 ASN A 112
GLN A  68
TYR A 475
MET A  24
 None
None
None
GOL  A 656 (-4.7A)
 1.29A 6hlpA-2zwsA:
0.0		 6hlpA-2zwsA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 204
HIS A  97
HIS A  99
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
 0.74A 6nknN-2zwsA:
undetectable		 6nknN-2zwsA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 204
HIS A  97
HIS A  99
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
 0.73A 6nmfN-2zwsA:
undetectable		 6nmfN-2zwsA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 204
HIS A  97
HIS A  99
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
GOL  A 656 ( 4.7A)
 0.72A 6nmpN-2zwsA:
undetectable		 6nmpN-2zwsA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6PAH_A_DAHA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 2zws NEUTRAL CERAMIDASE
(Pseudomonas
aeruginosa) 		4 / 6 HIS A 204
HIS A  97
TYR A 445
GLU A 411
 ZN  A 647 (-3.3A)
ZN  A 647 (-3.4A)
None
ZN  A 647 (-2.0A)
 0.94A 6pahA-2zwsA:
undetectable		 6pahA-2zwsA:
20.75