SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zwv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NV8_A_SAMA300_0 (HEMK PROTEIN)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	PHE A 207 GLY A 241 GLY A 243 ASN A 305 PRO A 307	SAH A 376 (-3.4A) SAH A 376 (-3.1A) SAH A 376 (-3.4A) SAH A 376 (-4.4A) SAH A 376 ( 4.3A)	0.36A	1nv8A-2zwvA: 13.5	1nv8A-2zwvA: 24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QAO_A_SAMA245_0 (ERMC' METHYLTRANSFERASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	6 / 12	GLY A 241 GLY A 243 ASP A 264 ASP A 288 ASN A 305 PRO A 307	SAH A 376 (-3.1A) SAH A 376 (-3.4A) None SAH A 376 (-4.1A) SAH A 376 (-4.4A) SAH A 376 ( 4.3A)	0.68A	1qaoA-2zwvA: 11.5	1qaoA-2zwvA: 18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SG9_C_SAMC303_0 (HEMK PROTEIN)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	PHE A 207 GLY A 243 ALA A 246 ASN A 305 PRO A 307	SAH A 376 (-3.4A) SAH A 376 (-3.4A) SAH A 376 (-3.3A) SAH A 376 (-4.4A) SAH A 376 ( 4.3A)	0.60A	1sg9C-2zwvA: 18.0	1sg9C-2zwvA: 23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YVP_B_ACTB2002_0 (60-KDA SS-A/RO RIBONUCLEOPROTEIN)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	4 / 6	SER A 190 ALA A 191 THR A 199 ASN A 278	None	1.03A	1yvpB-2zwvA: 2.5	1yvpB-2zwvA: 23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ADM_A_SAMA500_0 (ADENINE-N6-DNA-METHY LTRANSFERASE TAQI)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 11	GLU A 262 ASP A 264 ASP A 288 PRO A 307 PHE A 322	SAH A 376 (-2.7A) None SAH A 376 (-4.1A) SAH A 376 ( 4.3A) None	0.96A	2admA-2zwvA: 11.9	2admA-2zwvA: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AVV_E_MK1E902_4 (POL POLYPROTEIN)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	3 / 3	ARG A 163 VAL A 106 GLY A 57	None	0.53A	2avvE-2zwvA: undetectable	2avvE-2zwvA: 14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BR4_D_SAMD301_1 (CEPHALOSPORIN HYDROXYLASE CMCI)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	3 / 3	LYS A 24 ASP A 239 ASP A 288	None SAH A 376 ( 4.2A) SAH A 376 (-4.1A)	0.97A	2br4D-2zwvA: 8.9	2br4D-2zwvA: 21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2E1Q_D_SALD5006_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	4 / 5	ARG A 28 THR A 74 LEU A 91 ALA A 78	None	1.46A	2e1qD-2zwvA: undetectable	2e1qD-2zwvA: 15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2I91_A_ACTA601_0 (60 KDA SS-A/RO RIBONUCLEOPROTEIN)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	4 / 7	SER A 190 ALA A 191 THR A 199 ASN A 278	None	1.02A	2i91A-2zwvA: 2.5	2i91A-2zwvA: 23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2I91_B_ACTB602_0 (60 KDA SS-A/RO RIBONUCLEOPROTEIN)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	4 / 7	SER A 190 ALA A 191 THR A 199 ASN A 278	None	1.02A	2i91B-2zwvA: undetectable	2i91B-2zwvA: 23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NXE_A_SAMA302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	8 / 12	PHE A 207 ASP A 239 LEU A 240 GLY A 241 GLY A 243 LEU A 247 ASP A 264 ASN A 305	SAH A 376 (-3.4A) SAH A 376 ( 4.2A) None SAH A 376 (-3.1A) SAH A 376 (-3.4A) SAH A 376 ( 4.4A) None SAH A 376 (-4.4A)	0.63A	2nxeA-2zwvA: 16.3	2nxeA-2zwvA: 27.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NXE_B_SAMB303_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	7 / 12	PHE A 207 ASP A 239 GLY A 241 GLY A 243 LEU A 247 ASP A 264 ASN A 305	SAH A 376 (-3.4A) SAH A 376 ( 4.2A) SAH A 376 (-3.1A) SAH A 376 (-3.4A) SAH A 376 ( 4.4A) None SAH A 376 (-4.4A)	0.47A	2nxeB-2zwvA: 18.3	2nxeB-2zwvA: 27.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NXE_B_SAMB303_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	7 / 12	PHE A 207 ASP A 239 LEU A 240 GLY A 241 GLY A 243 LEU A 247 ASN A 305	SAH A 376 (-3.4A) SAH A 376 ( 4.2A) None SAH A 376 (-3.1A) SAH A 376 (-3.4A) SAH A 376 ( 4.4A) SAH A 376 (-4.4A)	0.55A	2nxeB-2zwvA: 18.3	2nxeB-2zwvA: 27.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Z0Y_A_SAMA300_0 (PUTATIVE UNCHARACTERIZED PROTEIN TTHA0657)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 9	ALA A 282 VAL A 258 GLY A 255 LEU A 275 LEU A 249	None	0.84A	2z0yA-2zwvA: 2.3	2z0yA-2zwvA: 26.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Z0Y_B_SAMB400_0 (PUTATIVE UNCHARACTERIZED PROTEIN TTHA0657)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 9	ALA A 282 VAL A 258 GLY A 255 LEU A 275 LEU A 249	None	0.79A	2z0yB-2zwvA: undetectable	2z0yB-2zwvA: 26.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZBP_A_SAMA300_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	6 / 12	PHE A 207 GLY A 241 GLY A 243 LEU A 247 ASP A 264 ASN A 305	SAH A 376 (-3.4A) SAH A 376 (-3.1A) SAH A 376 (-3.4A) SAH A 376 ( 4.4A) None SAH A 376 (-4.4A)	0.57A	2zbpA-2zwvA: 17.9	2zbpA-2zwvA: 27.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZBP_A_SAMA300_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	6 / 12	PHE A 207 LEU A 240 GLY A 241 GLY A 243 LEU A 247 ASN A 305	SAH A 376 (-3.4A) None SAH A 376 (-3.1A) SAH A 376 (-3.4A) SAH A 376 ( 4.4A) SAH A 376 (-4.4A)	0.63A	2zbpA-2zwvA: 17.9	2zbpA-2zwvA: 27.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2ZUL_A_SAMA376_0 (PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	7 / 12	PHE A 207 GLY A 241 GLY A 243 ALA A 246 VAL A 289 PRO A 306 PHE A 322	SAH A 376 (-3.4A) SAH A 376 (-3.1A) SAH A 376 (-3.4A) SAH A 376 (-3.3A) SAH A 376 (-4.0A) None None	1.49A	2zulA-2zwvA: 64.1	2zulA-2zwvA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2ZUL_A_SAMA376_0 (PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	6 / 12	TYR A 8 LEU A 219 ASN A 305 PRO A 307 VAL A 318 PHE A 322	None None SAH A 376 (-4.4A) SAH A 376 ( 4.3A) SAH A 376 (-4.5A) None	1.39A	2zulA-2zwvA: 64.1	2zulA-2zwvA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2ZUL_A_SAMA376_0 (PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	12 / 12	TYR A 8 PHE A 207 GLY A 241 GLY A 243 ALA A 246 LEU A 247 ASP A 263 VAL A 289 ASN A 305 PRO A 307 VAL A 318 PHE A 322	None SAH A 376 (-3.4A) SAH A 376 (-3.1A) SAH A 376 (-3.4A) SAH A 376 (-3.3A) SAH A 376 ( 4.4A) SAH A 376 (-4.2A) SAH A 376 (-4.0A) SAH A 376 (-4.4A) SAH A 376 ( 4.3A) SAH A 376 (-4.5A) None	0.10A	2zulA-2zwvA: 64.1	2zulA-2zwvA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2ZUL_A_SAMA376_1 (PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	3 / 3	SER A 216 GLU A 262 ASP A 288	SAH A 376 (-2.5A) SAH A 376 (-2.7A) SAH A 376 (-4.1A)	0.06A	2zulA-2zwvA: 64.1	2zulA-2zwvA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A302_1 (THIOPURINE S-METHYLTRANSFERASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	4 / 6	HIS A 286 GLN A 272 LEU A 265 LEU A 269	None	1.20A	3bgdA-2zwvA: 6.2	3bgdA-2zwvA: 23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CJT_G_SAMG302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	GLY A 241 GLY A 243 LEU A 247 ASP A 264 ASN A 305	SAH A 376 (-3.1A) SAH A 376 (-3.4A) SAH A 376 ( 4.4A) None SAH A 376 (-4.4A)	0.42A	3cjtG-2zwvA: 15.3	3cjtG-2zwvA: 27.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CJT_G_SAMG302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	LEU A 240 GLY A 241 GLY A 243 LEU A 247 ASN A 305	None SAH A 376 (-3.1A) SAH A 376 (-3.4A) SAH A 376 ( 4.4A) SAH A 376 (-4.4A)	0.60A	3cjtG-2zwvA: 15.3	3cjtG-2zwvA: 27.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CJT_O_SAMO302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	GLY A 241 GLY A 243 LEU A 247 ASP A 264 ASN A 305	SAH A 376 (-3.1A) SAH A 376 (-3.4A) SAH A 376 ( 4.4A) None SAH A 376 (-4.4A)	0.40A	3cjtO-2zwvA: 17.6	3cjtO-2zwvA: 27.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CJT_O_SAMO302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	LEU A 240 GLY A 241 GLY A 243 LEU A 247 ASN A 305	None SAH A 376 (-3.1A) SAH A 376 (-3.4A) SAH A 376 ( 4.4A) SAH A 376 (-4.4A)	0.59A	3cjtO-2zwvA: 17.6	3cjtO-2zwvA: 27.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DMF_A_SAMA388_0 (PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	12 / 12	TYR A 8 PHE A 207 GLY A 241 GLY A 243 ALA A 246 ASP A 263 ASP A 288 VAL A 289 ASN A 305 PRO A 307 VAL A 318 PHE A 322	None SAH A 376 (-3.4A) SAH A 376 (-3.1A) SAH A 376 (-3.4A) SAH A 376 (-3.3A) SAH A 376 (-4.2A) SAH A 376 (-4.1A) SAH A 376 (-4.0A) SAH A 376 (-4.4A) SAH A 376 ( 4.3A) SAH A 376 (-4.5A) None	0.18A	3dmfA-2zwvA: 61.8	3dmfA-2zwvA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DMH_A_SAMA384_0 (PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	12 / 12	TYR A 8 PHE A 207 GLY A 241 GLY A 243 ALA A 246 LEU A 247 ASP A 263 VAL A 289 ASN A 305 PRO A 307 VAL A 318 PHE A 322	None SAH A 376 (-3.4A) SAH A 376 (-3.1A) SAH A 376 (-3.4A) SAH A 376 (-3.3A) SAH A 376 ( 4.4A) SAH A 376 (-4.2A) SAH A 376 (-4.0A) SAH A 376 (-4.4A) SAH A 376 ( 4.3A) SAH A 376 (-4.5A) None	0.19A	3dmhA-2zwvA: 61.7	3dmhA-2zwvA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DMH_A_SAMA384_0 (PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	7 / 12	TYR A 8 PHE A 207 LEU A 219 ASN A 305 PRO A 307 VAL A 318 PHE A 322	None SAH A 376 (-3.4A) None SAH A 376 (-4.4A) SAH A 376 ( 4.3A) SAH A 376 (-4.5A) None	1.33A	3dmhA-2zwvA: 61.7	3dmhA-2zwvA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DMH_A_SAMA384_1 (PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	3 / 3	SER A 216 GLU A 262 ASP A 288	SAH A 376 (-2.5A) SAH A 376 (-2.7A) SAH A 376 (-4.1A)	0.05A	3dmhA-2zwvA: 61.7	3dmhA-2zwvA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ERD_B_DESB800_1 (ESTROGEN RECEPTOR ALPHA)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 10	GLU A 73 LEU A 87 LEU A 82 ARG A 28 MET A 67	None	1.39A	3erdB-2zwvA: undetectable	3erdB-2zwvA: 21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FUU_A_ADNA0_1 (DIMETHYLADENOSINE TRANSFERASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	GLY A 241 GLY A 243 GLU A 262 ASP A 264 ASP A 288	SAH A 376 (-3.1A) SAH A 376 (-3.4A) SAH A 376 (-2.7A) None SAH A 376 (-4.1A)	0.51A	3fuuA-2zwvA: 10.6	3fuuA-2zwvA: 27.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GRV_A_ADNA300_1 (DIMETHYLADENOSINE TRANSFERASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	6 / 11	GLY A 241 GLY A 243 GLU A 262 ASP A 264 ASN A 305 PRO A 307	SAH A 376 (-3.1A) SAH A 376 (-3.4A) SAH A 376 (-2.7A) None SAH A 376 (-4.4A) SAH A 376 ( 4.3A)	0.80A	3grvA-2zwvA: 11.2	3grvA-2zwvA: 22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GRY_A_SAMA300_0 (DIMETHYLADENOSINE TRANSFERASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	6 / 12	GLY A 241 GLU A 262 ASP A 264 ASP A 288 ASN A 305 PRO A 307	SAH A 376 (-3.1A) SAH A 376 (-2.7A) None SAH A 376 (-4.1A) SAH A 376 (-4.4A) SAH A 376 ( 4.3A)	0.94A	3gryA-2zwvA: 11.2	3gryA-2zwvA: 22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GRY_A_SAMA300_0 (DIMETHYLADENOSINE TRANSFERASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	6 / 12	GLY A 241 GLY A 243 ASP A 264 ASP A 288 ASN A 305 PRO A 307	SAH A 376 (-3.1A) SAH A 376 (-3.4A) None SAH A 376 (-4.1A) SAH A 376 (-4.4A) SAH A 376 ( 4.3A)	1.22A	3gryA-2zwvA: 11.2	3gryA-2zwvA: 22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LCV_B_SAMB301_0 (SISOMICIN-GENTAMICIN RESISTANCE METHYLASE SGM)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	TYR A 102 ALA A 125 ASP A 51 LEU A 107 LEU A 155	None	1.39A	3lcvB-2zwvA: 8.2	3lcvB-2zwvA: 24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LXI_B_CAMB423_0 (CYTOCHROME P450)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 11	LEU A 220 LEU A 223 VAL A 258 ASP A 239 VAL A 237	None None None SAH A 376 ( 4.2A) None	1.18A	3lxiB-2zwvA: undetectable	3lxiB-2zwvA: 25.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PP7_B_SVRB499_1 (PYRUVATE KINASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 10	ASN A 53 HIS A 35 GLY A 57 GLY A 139 ALA A 138	None	1.32A	3pp7B-2zwvA: 3.5	3pp7B-2zwvA: 22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R9T_A_BEZA264_0 (ECHA1_1)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	4 / 8	ALA A 152 LEU A 173 ALA A 125 ALA A 126	None	0.53A	3r9tA-2zwvA: undetectable	3r9tA-2zwvA: 25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V8V_A_SAMA801_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	GLY A 243 ASP A 264 VAL A 289 ASN A 305 PRO A 307	SAH A 376 (-3.4A) None SAH A 376 (-4.0A) SAH A 376 (-4.4A) SAH A 376 ( 4.3A)	0.62A	3v8vA-2zwvA: 13.3	3v8vA-2zwvA: 22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V8V_B_SAMB801_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	6 / 11	GLY A 243 ASP A 264 ASP A 288 VAL A 289 ASN A 305 PRO A 307	SAH A 376 (-3.4A) None SAH A 376 (-4.1A) SAH A 376 (-4.0A) SAH A 376 (-4.4A) SAH A 376 ( 4.3A)	0.65A	3v8vB-2zwvA: 12.7	3v8vB-2zwvA: 22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VYW_C_SAMC401_1 (MNMC2)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	4 / 6	GLY A 243 GLU A 262 ASP A 288 ASP A 239	SAH A 376 (-3.4A) SAH A 376 (-2.7A) SAH A 376 (-4.1A) SAH A 376 ( 4.2A)	0.89A	3vywC-2zwvA: 8.9	3vywC-2zwvA: 24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C9N_B_CAMB1420_0 (CYTOCHROME P450)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 10	LEU A 220 LEU A 223 VAL A 258 ASP A 239 VAL A 237	None None None SAH A 376 ( 4.2A) None	1.17A	4c9nB-2zwvA: undetectable	4c9nB-2zwvA: 25.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C9P_B_CAMB423_0 (CYTOCHROME P450)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 10	LEU A 220 LEU A 223 VAL A 258 ASP A 239 VAL A 237	None None None SAH A 376 ( 4.2A) None	1.21A	4c9pB-2zwvA: undetectable	4c9pB-2zwvA: 25.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CP4_A_CAMA416_0 (CYTOCHROME P450-CAM)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	4 / 7	LEU A 220 VAL A 258 ASP A 239 VAL A 237	None None SAH A 376 ( 4.2A) None	1.00A	4cp4A-2zwvA: undetectable	4cp4A-2zwvA: 24.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DCM_A_SAMA401_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE G)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	6 / 11	PHE A 207 ASP A 239 GLY A 241 GLY A 243 ASN A 305 PRO A 307	SAH A 376 (-3.4A) SAH A 376 ( 4.2A) SAH A 376 (-3.1A) SAH A 376 (-3.4A) SAH A 376 (-4.4A) SAH A 376 ( 4.3A)	0.53A	4dcmA-2zwvA: 33.6	4dcmA-2zwvA: 27.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E1G_A_LNLA701_2 (PROSTAGLANDIN G/H SYNTHASE 2)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	4 / 5	ARG A 329 VAL A 261 LEU A 285 SER A 287	None	1.36A	4e1gA-2zwvA: undetectable	4e1gA-2zwvA: 20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FO4_B_MOAB502_1 (INOSINE 5'-MONOPHOSPHATE DEHYDROGENASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	4 / 8	SER A 267 GLY A 260 THR A 248 GLY A 274	SAH A 376 ( 4.4A) None None None	0.86A	4fo4B-2zwvA: undetectable	4fo4B-2zwvA: 23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GC9_A_SAMA401_1 (DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	3 / 3	GLU A 262 ASP A 264 ASP A 288	SAH A 376 (-2.7A) None SAH A 376 (-4.1A)	0.33A	4gc9A-2zwvA: 8.1	4gc9A-2zwvA: 24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LVC_B_ADNB501_1 (S-ADENOSYL-L-HOMOCYS TEINE HYDROLASE (SAHASE))	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	LEU A 293 ASP A 290 HIS A 9 GLY A 241 PHE A 299	None None None SAH A 376 (-3.1A) None	1.38A	4lvcB-2zwvA: 3.9	4lvcB-2zwvA: 24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q15_A_HFGA803_1 (PROLINE--TRNA LIGASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	3 / 3	GLU A 276 THR A 199 HIS A 201	None	0.84A	4q15A-2zwvA: undetectable	4q15A-2zwvA: 20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q15_B_HFGB803_1 (PROLINE--TRNA LIGASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	3 / 3	GLU A 276 THR A 199 HIS A 201	None	0.82A	4q15B-2zwvA: undetectable	4q15B-2zwvA: 20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QTU_D_SAMD301_1 (PUTATIVE METHYLTRANSFERASE BUD23)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	4 / 5	GLN A 272 LEU A 271 SER A 270 ASP A 264	None	1.23A	4qtuD-2zwvA: 14.2	4qtuD-2zwvA: 19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RET_C_DGXC2005_1 (SODIUM/POTASSIUM-TRA NSPORTING ATPASE SUBUNIT ALPHA-1)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	GLU A 73 LEU A 50 LEU A 269 ALA A 125 ARG A 113	None	1.18A	4retC-2zwvA: undetectable	4retC-2zwvA: 18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YDQ_B_HFGB802_1 (PROLINE--TRNA LIGASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	3 / 3	GLU A 276 THR A 199 HIS A 201	None	0.77A	4ydqB-2zwvA: undetectable	4ydqB-2zwvA: 21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZBQ_A_DIFA601_1 (SERUM ALBUMIN)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 11	LEU A 107 ASN A 53 GLY A 57 SER A 60 LEU A 38	None	1.27A	4zbqA-2zwvA: 1.2	4zbqA-2zwvA: 21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZN7_B_DESB600_1 (ESTROGEN RECEPTOR)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 11	GLU A 73 LEU A 87 LEU A 82 ARG A 28 MET A 67	None	1.35A	4zn7B-2zwvA: undetectable	4zn7B-2zwvA: 21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DL9_A_ACTA214_0 (LYSOZYME C)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	4 / 5	GLU A 73 ASP A 51 VAL A 56 ALA A 78	None	1.47A	5dl9A-2zwvA: undetectable	5dl9A-2zwvA: 16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ERG_B_SAMB401_1 (TRNA (ADENINE(58)-N(1))-M ETHYLTRANSFERASE CATALYTIC SUBUNIT TRM61)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	4 / 7	GLY A 241 GLY A 243 GLU A 262 ASP A 288	SAH A 376 (-3.1A) SAH A 376 (-3.4A) SAH A 376 (-2.7A) SAH A 376 (-4.1A)	0.75A	5ergB-2zwvA: 13.9	5ergB-2zwvA: 22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_A_ADNA501_1 (ADENOSYLHOMOCYSTEINA SE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	LEU A 293 ASP A 290 HIS A 9 GLY A 241 PHE A 299	None None None SAH A 376 (-3.1A) None	1.32A	5hm8A-2zwvA: 6.1	5hm8A-2zwvA: 22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_B_ADNB501_1 (ADENOSYLHOMOCYSTEINA SE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	LEU A 293 ASP A 290 HIS A 9 GLY A 241 PHE A 299	None None None SAH A 376 (-3.1A) None	1.32A	5hm8B-2zwvA: 6.1	5hm8B-2zwvA: 22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_C_ADNC501_1 (ADENOSYLHOMOCYSTEINA SE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	LEU A 293 ASP A 290 HIS A 9 GLY A 241 PHE A 299	None None None SAH A 376 (-3.1A) None	1.31A	5hm8C-2zwvA: 7.9	5hm8C-2zwvA: 22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_D_ADND501_1 (ADENOSYLHOMOCYSTEINA SE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	LEU A 293 ASP A 290 HIS A 9 GLY A 241 PHE A 299	None None None SAH A 376 (-3.1A) None	1.31A	5hm8D-2zwvA: 5.5	5hm8D-2zwvA: 22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_E_ADNE501_1 (ADENOSYLHOMOCYSTEINA SE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	LEU A 293 ASP A 290 HIS A 9 GLY A 241 PHE A 299	None None None SAH A 376 (-3.1A) None	1.31A	5hm8E-2zwvA: 3.8	5hm8E-2zwvA: 22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_F_ADNF501_1 (ADENOSYLHOMOCYSTEINA SE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	LEU A 293 ASP A 290 HIS A 9 GLY A 241 PHE A 299	None None None SAH A 376 (-3.1A) None	1.32A	5hm8F-2zwvA: 4.0	5hm8F-2zwvA: 22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_G_ADNG501_1 (ADENOSYLHOMOCYSTEINA SE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	LEU A 293 ASP A 290 HIS A 9 GLY A 241 PHE A 299	None None None SAH A 376 (-3.1A) None	1.31A	5hm8G-2zwvA: 3.9	5hm8G-2zwvA: 22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_H_ADNH501_1 (ADENOSYLHOMOCYSTEINA SE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	LEU A 293 ASP A 290 HIS A 9 GLY A 241 PHE A 299	None None None SAH A 376 (-3.1A) None	1.32A	5hm8H-2zwvA: 5.5	5hm8H-2zwvA: 22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MVS_A_ADNA401_1 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	4 / 7	GLY A 241 GLU A 262 ASP A 288 ASN A 305	SAH A 376 (-3.1A) SAH A 376 (-2.7A) SAH A 376 (-4.1A) SAH A 376 (-4.4A)	0.51A	5mvsA-2zwvA: 12.2	5mvsA-2zwvA: 21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MVS_B_ADNB401_1 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	4 / 8	GLY A 241 GLU A 262 ASP A 288 ASN A 305	SAH A 376 (-3.1A) SAH A 376 (-2.7A) SAH A 376 (-4.1A) SAH A 376 (-4.4A)	0.53A	5mvsB-2zwvA: 11.4	5mvsB-2zwvA: 21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0O_A_SAMA501_0 (PEPTIDE N-METHYLTRANSFERASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	HIS A 202 VAL A 206 SER A 270 ALA A 284 VAL A 261	None	1.19A	5n0oA-2zwvA: 2.4	5n0oA-2zwvA: 20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0S_B_SAMB501_0 (PEPTIDE N-METHYLTRANSFERASE)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	HIS A 202 VAL A 206 SER A 270 ALA A 284 VAL A 261	None	1.18A	5n0sB-2zwvA: 2.5	5n0sB-2zwvA: 21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ND3_B_TA1B601_1 (TUBULIN BETA-2B CHAIN)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	GLU A 73 LEU A 3 ALA A 77 SER A 75 ARG A 28	None	1.19A	5nd3B-2zwvA: 2.4	5nd3B-2zwvA: 23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X80_D_SALD201_1 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	4 / 5	GLY A 114 TYR A 117 VAL A 206 ARG A 113	None	1.37A	5x80C-2zwvA: undetectable 5x80D-2zwvA: undetectable	5x80C-2zwvA: 20.53 5x80D-2zwvA: 20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A7J_A_TESA502_0 (CYTOCHROME P450)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	4 / 7	LEU A 137 LEU A 135 ALA A 126 ALA A 125	None	0.68A	6a7jA-2zwvA: undetectable	6a7jA-2zwvA: 12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_B_TA1B501_1 (TUBULIN BETA CHAIN)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	ASP A 51 LEU A 185 LEU A 203 ALA A 97 LEU A 182	None	1.12A	6ew0B-2zwvA: 2.3	6ew0B-2zwvA: 11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_D_TA1D501_1 (TUBULIN BETA CHAIN)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	ASP A 51 LEU A 185 LEU A 203 ALA A 97 LEU A 182	None	1.12A	6ew0D-2zwvA: 2.5	6ew0D-2zwvA: 11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_H_TA1H501_1 (TUBULIN BETA CHAIN)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	ASP A 51 LEU A 185 LEU A 203 ALA A 97 LEU A 182	None	1.12A	6ew0H-2zwvA: 3.0	6ew0H-2zwvA: 11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_I_TA1I501_1 (TUBULIN BETA CHAIN)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	ASP A 51 LEU A 185 LEU A 203 ALA A 97 LEU A 182	None	1.12A	6ew0I-2zwvA: 2.5	6ew0I-2zwvA: 11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6IFT_A_SAMA301_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE A)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	GLY A 241 ALA A 246 ASP A 264 VAL A 289 PRO A 307	SAH A 376 (-3.1A) SAH A 376 (-3.3A) None SAH A 376 (-4.0A) SAH A 376 ( 4.3A)	0.79A	6iftA-2zwvA: 9.2	6iftA-2zwvA: 21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6IFT_A_SAMA301_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE A)	2zwv	PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	GLY A 241 GLY A 243 ALA A 246 ASP A 264 PRO A 307	SAH A 376 (-3.1A) SAH A 376 (-3.4A) SAH A 376 (-3.3A) None SAH A 376 ( 4.3A)	0.57A	6iftA-2zwvA: 9.2	6iftA-2zwvA: 21.84

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1NV8_A_SAMA300_0","HEMK PROTEIN","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"PHE A 207;GLY A 241;GLY A 243;ASN A 305;PRO A 307","SAH A 376 (-3.4A);SAH A 376 (-3.1A);SAH A 376 (-3.4A);SAH A 376 (-4.4A);SAH A 376 ( 4.3A)","0.36A","1nv8A-2zwvA:13.5","1nv8A-2zwvA:24.39"],["1QAO_A_SAMA245_0","ERMC' METHYLTRANSFERASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",6,"GLY A 241;GLY A 243;ASP A 264;ASP A 288;ASN A 305;PRO A 307","SAH A 376 (-3.1A);SAH A 376 (-3.4A);None;SAH A 376 (-4.1A);SAH A 376 (-4.4A);SAH A 376 ( 4.3A)","0.68A","1qaoA-2zwvA:11.5","1qaoA-2zwvA:18.57"],["1SG9_C_SAMC303_0","HEMK PROTEIN","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"PHE A 207;GLY A 243;ALA A 246;ASN A 305;PRO A 307","SAH A 376 (-3.4A);SAH A 376 (-3.4A);SAH A 376 (-3.3A);SAH A 376 (-4.4A);SAH A 376 ( 4.3A)","0.60A","1sg9C-2zwvA:18.0","1sg9C-2zwvA:23.35"],["1YVP_B_ACTB2002_0","60-KDA SS-A\/RO RIBONUCLEOPROTEIN","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",4,"SER A 190;ALA A 191;THR A 199;ASN A 278","None","1.03A","1yvpB-2zwvA:2.5","1yvpB-2zwvA:23.89"],["2ADM_A_SAMA500_0","ADENINE-N6-DNA-METHYLTRANSFERASE TAQI","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"GLU A 262;ASP A 264;ASP A 288;PRO A 307;PHE A 322","SAH A 376 (-2.7A);None;SAH A 376 (-4.1A);SAH A 376 ( 4.3A);None","0.96A","2admA-2zwvA:11.9","2admA-2zwvA:23.56"],["2AVV_E_MK1E902_4","POL POLYPROTEIN","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",3,"ARG A 163;VAL A 106;GLY A  57","None","0.53A","2avvE-2zwvA:undetectable","2avvE-2zwvA:14.63"],["2BR4_D_SAMD301_1","CEPHALOSPORIN HYDROXYLASE CMCI","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",3,"LYS A  24;ASP A 239;ASP A 288","None;SAH A 376 ( 4.2A);SAH A 376 (-4.1A)","0.97A","2br4D-2zwvA:8.9","2br4D-2zwvA:21.96"],["2E1Q_D_SALD5006_1","XANTHINE DEHYDROGENASE\/OXIDASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",4,"ARG A  28;THR A  74;LEU A  91;ALA A  78","None","1.46A","2e1qD-2zwvA:undetectable","2e1qD-2zwvA:15.47"],["2I91_A_ACTA601_0","60 KDA SS-A\/RO RIBONUCLEOPROTEIN","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",4,"SER A 190;ALA A 191;THR A 199;ASN A 278","None","1.02A","2i91A-2zwvA:2.5","2i91A-2zwvA:23.89"],["2I91_B_ACTB602_0","60 KDA SS-A\/RO RIBONUCLEOPROTEIN","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",4,"SER A 190;ALA A 191;THR A 199;ASN A 278","None","1.02A","2i91B-2zwvA:undetectable","2i91B-2zwvA:23.89"],["2NXE_A_SAMA302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",8,"PHE A 207;ASP A 239;LEU A 240;GLY A 241;GLY A 243;LEU A 247;ASP A 264;ASN A 305","SAH A 376 (-3.4A);SAH A 376 ( 4.2A);None;SAH A 376 (-3.1A);SAH A 376 (-3.4A);SAH A 376 ( 4.4A);None;SAH A 376 (-4.4A)","0.63A","2nxeA-2zwvA:16.3","2nxeA-2zwvA:27.76"],["2NXE_B_SAMB303_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",7,"PHE A 207;ASP A 239;GLY A 241;GLY A 243;LEU A 247;ASP A 264;ASN A 305","SAH A 376 (-3.4A);SAH A 376 ( 4.2A);SAH A 376 (-3.1A);SAH A 376 (-3.4A);SAH A 376 ( 4.4A);None;SAH A 376 (-4.4A)","0.47A","2nxeB-2zwvA:18.3","2nxeB-2zwvA:27.76"],["2NXE_B_SAMB303_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",7,"PHE A 207;ASP A 239;LEU A 240;GLY A 241;GLY A 243;LEU A 247;ASN A 305","SAH A 376 (-3.4A);SAH A 376 ( 4.2A);None;SAH A 376 (-3.1A);SAH A 376 (-3.4A);SAH A 376 ( 4.4A);SAH A 376 (-4.4A)","0.55A","2nxeB-2zwvA:18.3","2nxeB-2zwvA:27.76"],["2Z0Y_A_SAMA300_0","PUTATIVE UNCHARACTERIZED PROTEIN TTHA0657","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"ALA A 282;VAL A 258;GLY A 255;LEU A 275;LEU A 249","None","0.84A","2z0yA-2zwvA:2.3","2z0yA-2zwvA:26.68"],["2Z0Y_B_SAMB400_0","PUTATIVE UNCHARACTERIZED PROTEIN TTHA0657","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"ALA A 282;VAL A 258;GLY A 255;LEU A 275;LEU A 249","None","0.79A","2z0yB-2zwvA:undetectable","2z0yB-2zwvA:26.68"],["2ZBP_A_SAMA300_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",6,"PHE A 207;GLY A 241;GLY A 243;LEU A 247;ASP A 264;ASN A 305","SAH A 376 (-3.4A);SAH A 376 (-3.1A);SAH A 376 (-3.4A);SAH A 376 ( 4.4A);None;SAH A 376 (-4.4A)","0.57A","2zbpA-2zwvA:17.9","2zbpA-2zwvA:27.76"],["2ZBP_A_SAMA300_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",6,"PHE A 207;LEU A 240;GLY A 241;GLY A 243;LEU A 247;ASN A 305","SAH A 376 (-3.4A);None;SAH A 376 (-3.1A);SAH A 376 (-3.4A);SAH A 376 ( 4.4A);SAH A 376 (-4.4A)","0.63A","2zbpA-2zwvA:17.9","2zbpA-2zwvA:27.76"],["2ZUL_A_SAMA376_0","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",7,"PHE A 207;GLY A 241;GLY A 243;ALA A 246;VAL A 289;PRO A 306;PHE A 322","SAH A 376 (-3.4A);SAH A 376 (-3.1A);SAH A 376 (-3.4A);SAH A 376 (-3.3A);SAH A 376 (-4.0A);None;None","1.49A","2zulA-2zwvA:64.1","2zulA-2zwvA:100.00"],["2ZUL_A_SAMA376_0","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",6,"TYR A   8;LEU A 219;ASN A 305;PRO A 307;VAL A 318;PHE A 322","None;None;SAH A 376 (-4.4A);SAH A 376 ( 4.3A);SAH A 376 (-4.5A);None","1.39A","2zulA-2zwvA:64.1","2zulA-2zwvA:100.00"],["2ZUL_A_SAMA376_0","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",12,"TYR A   8;PHE A 207;GLY A 241;GLY A 243;ALA A 246;LEU A 247;ASP A 263;VAL A 289;ASN A 305;PRO A 307;VAL A 318;PHE A 322","None;SAH A 376 (-3.4A);SAH A 376 (-3.1A);SAH A 376 (-3.4A);SAH A 376 (-3.3A);SAH A 376 ( 4.4A);SAH A 376 (-4.2A);SAH A 376 (-4.0A);SAH A 376 (-4.4A);SAH A 376 ( 4.3A);SAH A 376 (-4.5A);None","0.10A","2zulA-2zwvA:64.1","2zulA-2zwvA:100.00"],["2ZUL_A_SAMA376_1","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",3,"SER A 216;GLU A 262;ASP A 288","SAH A 376 (-2.5A);SAH A 376 (-2.7A);SAH A 376 (-4.1A)","0.06A","2zulA-2zwvA:64.1","2zulA-2zwvA:100.00"],["3BGD_A_PM6A302_1","THIOPURINE S-METHYLTRANSFERASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",4,"HIS A 286;GLN A 272;LEU A 265;LEU A 269","None","1.20A","3bgdA-2zwvA:6.2","3bgdA-2zwvA:23.59"],["3CJT_G_SAMG302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"GLY A 241;GLY A 243;LEU A 247;ASP A 264;ASN A 305","SAH A 376 (-3.1A);SAH A 376 (-3.4A);SAH A 376 ( 4.4A);None;SAH A 376 (-4.4A)","0.42A","3cjtG-2zwvA:15.3","3cjtG-2zwvA:27.76"],["3CJT_G_SAMG302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"LEU A 240;GLY A 241;GLY A 243;LEU A 247;ASN A 305","None;SAH A 376 (-3.1A);SAH A 376 (-3.4A);SAH A 376 ( 4.4A);SAH A 376 (-4.4A)","0.60A","3cjtG-2zwvA:15.3","3cjtG-2zwvA:27.76"],["3CJT_O_SAMO302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"GLY A 241;GLY A 243;LEU A 247;ASP A 264;ASN A 305","SAH A 376 (-3.1A);SAH A 376 (-3.4A);SAH A 376 ( 4.4A);None;SAH A 376 (-4.4A)","0.40A","3cjtO-2zwvA:17.6","3cjtO-2zwvA:27.76"],["3CJT_O_SAMO302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"LEU A 240;GLY A 241;GLY A 243;LEU A 247;ASN A 305","None;SAH A 376 (-3.1A);SAH A 376 (-3.4A);SAH A 376 ( 4.4A);SAH A 376 (-4.4A)","0.59A","3cjtO-2zwvA:17.6","3cjtO-2zwvA:27.76"],["3DMF_A_SAMA388_0","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",12,"TYR A   8;PHE A 207;GLY A 241;GLY A 243;ALA A 246;ASP A 263;ASP A 288;VAL A 289;ASN A 305;PRO A 307;VAL A 318;PHE A 322","None;SAH A 376 (-3.4A);SAH A 376 (-3.1A);SAH A 376 (-3.4A);SAH A 376 (-3.3A);SAH A 376 (-4.2A);SAH A 376 (-4.1A);SAH A 376 (-4.0A);SAH A 376 (-4.4A);SAH A 376 ( 4.3A);SAH A 376 (-4.5A);None","0.18A","3dmfA-2zwvA:61.8","3dmfA-2zwvA:100.00"],["3DMH_A_SAMA384_0","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",12,"TYR A   8;PHE A 207;GLY A 241;GLY A 243;ALA A 246;LEU A 247;ASP A 263;VAL A 289;ASN A 305;PRO A 307;VAL A 318;PHE A 322","None;SAH A 376 (-3.4A);SAH A 376 (-3.1A);SAH A 376 (-3.4A);SAH A 376 (-3.3A);SAH A 376 ( 4.4A);SAH A 376 (-4.2A);SAH A 376 (-4.0A);SAH A 376 (-4.4A);SAH A 376 ( 4.3A);SAH A 376 (-4.5A);None","0.19A","3dmhA-2zwvA:61.7","3dmhA-2zwvA:100.00"],["3DMH_A_SAMA384_0","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",7,"TYR A   8;PHE A 207;LEU A 219;ASN A 305;PRO A 307;VAL A 318;PHE A 322","None;SAH A 376 (-3.4A);None;SAH A 376 (-4.4A);SAH A 376 ( 4.3A);SAH A 376 (-4.5A);None","1.33A","3dmhA-2zwvA:61.7","3dmhA-2zwvA:100.00"],["3DMH_A_SAMA384_1","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",3,"SER A 216;GLU A 262;ASP A 288","SAH A 376 (-2.5A);SAH A 376 (-2.7A);SAH A 376 (-4.1A)","0.05A","3dmhA-2zwvA:61.7","3dmhA-2zwvA:100.00"],["3ERD_B_DESB800_1","ESTROGEN RECEPTOR ALPHA","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"GLU A  73;LEU A  87;LEU A  82;ARG A  28;MET A  67","None","1.39A","3erdB-2zwvA:undetectable","3erdB-2zwvA:21.26"],["3FUU_A_ADNA0_1","DIMETHYLADENOSINE TRANSFERASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"GLY A 241;GLY A 243;GLU A 262;ASP A 264;ASP A 288","SAH A 376 (-3.1A);SAH A 376 (-3.4A);SAH A 376 (-2.7A);None;SAH A 376 (-4.1A)","0.51A","3fuuA-2zwvA:10.6","3fuuA-2zwvA:27.13"],["3GRV_A_ADNA300_1","DIMETHYLADENOSINE TRANSFERASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",6,"GLY A 241;GLY A 243;GLU A 262;ASP A 264;ASN A 305;PRO A 307","SAH A 376 (-3.1A);SAH A 376 (-3.4A);SAH A 376 (-2.7A);None;SAH A 376 (-4.4A);SAH A 376 ( 4.3A)","0.80A","3grvA-2zwvA:11.2","3grvA-2zwvA:22.66"],["3GRY_A_SAMA300_0","DIMETHYLADENOSINE TRANSFERASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",6,"GLY A 241;GLU A 262;ASP A 264;ASP A 288;ASN A 305;PRO A 307","SAH A 376 (-3.1A);SAH A 376 (-2.7A);None;SAH A 376 (-4.1A);SAH A 376 (-4.4A);SAH A 376 ( 4.3A)","0.94A","3gryA-2zwvA:11.2","3gryA-2zwvA:22.66"],["3GRY_A_SAMA300_0","DIMETHYLADENOSINE TRANSFERASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",6,"GLY A 241;GLY A 243;ASP A 264;ASP A 288;ASN A 305;PRO A 307","SAH A 376 (-3.1A);SAH A 376 (-3.4A);None;SAH A 376 (-4.1A);SAH A 376 (-4.4A);SAH A 376 ( 4.3A)","1.22A","3gryA-2zwvA:11.2","3gryA-2zwvA:22.66"],["3LCV_B_SAMB301_0","SISOMICIN-GENTAMICIN RESISTANCE METHYLASE SGM","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"TYR A 102;ALA A 125;ASP A  51;LEU A 107;LEU A 155","None","1.39A","3lcvB-2zwvA:8.2","3lcvB-2zwvA:24.94"],["3LXI_B_CAMB423_0","CYTOCHROME P450","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"LEU A 220;LEU A 223;VAL A 258;ASP A 239;VAL A 237","None;None;None;SAH A 376 ( 4.2A);None","1.18A","3lxiB-2zwvA:undetectable","3lxiB-2zwvA:25.16"],["3PP7_B_SVRB499_1","PYRUVATE KINASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"ASN A  53;HIS A  35;GLY A  57;GLY A 139;ALA A 138","None","1.32A","3pp7B-2zwvA:3.5","3pp7B-2zwvA:22.03"],["3R9T_A_BEZA264_0","ECHA1_1","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",4,"ALA A 152;LEU A 173;ALA A 125;ALA A 126","None","0.53A","3r9tA-2zwvA:undetectable","3r9tA-2zwvA:25.32"],["3V8V_A_SAMA801_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"GLY A 243;ASP A 264;VAL A 289;ASN A 305;PRO A 307","SAH A 376 (-3.4A);None;SAH A 376 (-4.0A);SAH A 376 (-4.4A);SAH A 376 ( 4.3A)","0.62A","3v8vA-2zwvA:13.3","3v8vA-2zwvA:22.46"],["3V8V_B_SAMB801_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",6,"GLY A 243;ASP A 264;ASP A 288;VAL A 289;ASN A 305;PRO A 307","SAH A 376 (-3.4A);None;SAH A 376 (-4.1A);SAH A 376 (-4.0A);SAH A 376 (-4.4A);SAH A 376 ( 4.3A)","0.65A","3v8vB-2zwvA:12.7","3v8vB-2zwvA:22.46"],["3VYW_C_SAMC401_1","MNMC2","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",4,"GLY A 243;GLU A 262;ASP A 288;ASP A 239","SAH A 376 (-3.4A);SAH A 376 (-2.7A);SAH A 376 (-4.1A);SAH A 376 ( 4.2A)","0.89A","3vywC-2zwvA:8.9","3vywC-2zwvA:24.32"],["4C9N_B_CAMB1420_0","CYTOCHROME P450","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"LEU A 220;LEU A 223;VAL A 258;ASP A 239;VAL A 237","None;None;None;SAH A 376 ( 4.2A);None","1.17A","4c9nB-2zwvA:undetectable","4c9nB-2zwvA:25.16"],["4C9P_B_CAMB423_0","CYTOCHROME P450","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"LEU A 220;LEU A 223;VAL A 258;ASP A 239;VAL A 237","None;None;None;SAH A 376 ( 4.2A);None","1.21A","4c9pB-2zwvA:undetectable","4c9pB-2zwvA:25.16"],["4CP4_A_CAMA416_0","CYTOCHROME P450-CAM","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",4,"LEU A 220;VAL A 258;ASP A 239;VAL A 237","None;None;SAH A 376 ( 4.2A);None","1.00A","4cp4A-2zwvA:undetectable","4cp4A-2zwvA:24.85"],["4DCM_A_SAMA401_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE G","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",6,"PHE A 207;ASP A 239;GLY A 241;GLY A 243;ASN A 305;PRO A 307","SAH A 376 (-3.4A);SAH A 376 ( 4.2A);SAH A 376 (-3.1A);SAH A 376 (-3.4A);SAH A 376 (-4.4A);SAH A 376 ( 4.3A)","0.53A","4dcmA-2zwvA:33.6","4dcmA-2zwvA:27.90"],["4E1G_A_LNLA701_2","PROSTAGLANDIN G\/H SYNTHASE 2","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",4,"ARG A 329;VAL A 261;LEU A 285;SER A 287","None","1.36A","4e1gA-2zwvA:undetectable","4e1gA-2zwvA:20.65"],["4FO4_B_MOAB502_1","INOSINE 5'-MONOPHOSPHATE DEHYDROGENASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",4,"SER A 267;GLY A 260;THR A 248;GLY A 274","SAH A 376 ( 4.4A);None;None;None","0.86A","4fo4B-2zwvA:undetectable","4fo4B-2zwvA:23.00"],["4GC9_A_SAMA401_1","DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",3,"GLU A 262;ASP A 264;ASP A 288","SAH A 376 (-2.7A);None;SAH A 376 (-4.1A)","0.33A","4gc9A-2zwvA:8.1","4gc9A-2zwvA:24.06"],["4LVC_B_ADNB501_1","S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE (SAHASE)","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"LEU A 293;ASP A 290;HIS A   9;GLY A 241;PHE A 299","None;None;None;SAH A 376 (-3.1A);None","1.38A","4lvcB-2zwvA:3.9","4lvcB-2zwvA:24.11"],["4Q15_A_HFGA803_1","PROLINE--TRNA LIGASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",3,"GLU A 276;THR A 199;HIS A 201","None","0.84A","4q15A-2zwvA:undetectable","4q15A-2zwvA:20.90"],["4Q15_B_HFGB803_1","PROLINE--TRNA LIGASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",3,"GLU A 276;THR A 199;HIS A 201","None","0.82A","4q15B-2zwvA:undetectable","4q15B-2zwvA:20.90"],["4QTU_D_SAMD301_1","PUTATIVE METHYLTRANSFERASE BUD23","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",4,"GLN A 272;LEU A 271;SER A 270;ASP A 264","None","1.23A","4qtuD-2zwvA:14.2","4qtuD-2zwvA:19.10"],["4RET_C_DGXC2005_1","SODIUM\/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-1","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"GLU A  73;LEU A  50;LEU A 269;ALA A 125;ARG A 113","None","1.18A","4retC-2zwvA:undetectable","4retC-2zwvA:18.64"],["4YDQ_B_HFGB802_1","PROLINE--TRNA LIGASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",3,"GLU A 276;THR A 199;HIS A 201","None","0.77A","4ydqB-2zwvA:undetectable","4ydqB-2zwvA:21.35"],["4ZBQ_A_DIFA601_1","SERUM ALBUMIN","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"LEU A 107;ASN A  53;GLY A  57;SER A  60;LEU A  38","None","1.27A","4zbqA-2zwvA:1.2","4zbqA-2zwvA:21.76"],["4ZN7_B_DESB600_1","ESTROGEN RECEPTOR","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"GLU A  73;LEU A  87;LEU A  82;ARG A  28;MET A  67","None","1.35A","4zn7B-2zwvA:undetectable","4zn7B-2zwvA:21.41"],["5DL9_A_ACTA214_0","LYSOZYME C","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",4,"GLU A  73;ASP A  51;VAL A  56;ALA A  78","None","1.47A","5dl9A-2zwvA:undetectable","5dl9A-2zwvA:16.43"],["5ERG_B_SAMB401_1","TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE CATALYTIC SUBUNIT TRM61","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",4,"GLY A 241;GLY A 243;GLU A 262;ASP A 288","SAH A 376 (-3.1A);SAH A 376 (-3.4A);SAH A 376 (-2.7A);SAH A 376 (-4.1A)","0.75A","5ergB-2zwvA:13.9","5ergB-2zwvA:22.41"],["5HM8_A_ADNA501_1","ADENOSYLHOMOCYSTEINASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"LEU A 293;ASP A 290;HIS A   9;GLY A 241;PHE A 299","None;None;None;SAH A 376 (-3.1A);None","1.32A","5hm8A-2zwvA:6.1","5hm8A-2zwvA:22.31"],["5HM8_B_ADNB501_1","ADENOSYLHOMOCYSTEINASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"LEU A 293;ASP A 290;HIS A   9;GLY A 241;PHE A 299","None;None;None;SAH A 376 (-3.1A);None","1.32A","5hm8B-2zwvA:6.1","5hm8B-2zwvA:22.31"],["5HM8_C_ADNC501_1","ADENOSYLHOMOCYSTEINASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"LEU A 293;ASP A 290;HIS A   9;GLY A 241;PHE A 299","None;None;None;SAH A 376 (-3.1A);None","1.31A","5hm8C-2zwvA:7.9","5hm8C-2zwvA:22.31"],["5HM8_D_ADND501_1","ADENOSYLHOMOCYSTEINASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"LEU A 293;ASP A 290;HIS A   9;GLY A 241;PHE A 299","None;None;None;SAH A 376 (-3.1A);None","1.31A","5hm8D-2zwvA:5.5","5hm8D-2zwvA:22.31"],["5HM8_E_ADNE501_1","ADENOSYLHOMOCYSTEINASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"LEU A 293;ASP A 290;HIS A   9;GLY A 241;PHE A 299","None;None;None;SAH A 376 (-3.1A);None","1.31A","5hm8E-2zwvA:3.8","5hm8E-2zwvA:22.31"],["5HM8_F_ADNF501_1","ADENOSYLHOMOCYSTEINASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"LEU A 293;ASP A 290;HIS A   9;GLY A 241;PHE A 299","None;None;None;SAH A 376 (-3.1A);None","1.32A","5hm8F-2zwvA:4.0","5hm8F-2zwvA:22.31"],["5HM8_G_ADNG501_1","ADENOSYLHOMOCYSTEINASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"LEU A 293;ASP A 290;HIS A   9;GLY A 241;PHE A 299","None;None;None;SAH A 376 (-3.1A);None","1.31A","5hm8G-2zwvA:3.9","5hm8G-2zwvA:22.31"],["5HM8_H_ADNH501_1","ADENOSYLHOMOCYSTEINASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"LEU A 293;ASP A 290;HIS A   9;GLY A 241;PHE A 299","None;None;None;SAH A 376 (-3.1A);None","1.32A","5hm8H-2zwvA:5.5","5hm8H-2zwvA:22.31"],["5MVS_A_ADNA401_1","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",4,"GLY A 241;GLU A 262;ASP A 288;ASN A 305","SAH A 376 (-3.1A);SAH A 376 (-2.7A);SAH A 376 (-4.1A);SAH A 376 (-4.4A)","0.51A","5mvsA-2zwvA:12.2","5mvsA-2zwvA:21.31"],["5MVS_B_ADNB401_1","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",4,"GLY A 241;GLU A 262;ASP A 288;ASN A 305","SAH A 376 (-3.1A);SAH A 376 (-2.7A);SAH A 376 (-4.1A);SAH A 376 (-4.4A)","0.53A","5mvsB-2zwvA:11.4","5mvsB-2zwvA:21.31"],["5N0O_A_SAMA501_0","PEPTIDE N-METHYLTRANSFERASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"HIS A 202;VAL A 206;SER A 270;ALA A 284;VAL A 261","None","1.19A","5n0oA-2zwvA:2.4","5n0oA-2zwvA:20.18"],["5N0S_B_SAMB501_0","PEPTIDE N-METHYLTRANSFERASE","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"HIS A 202;VAL A 206;SER A 270;ALA A 284;VAL A 261","None","1.18A","5n0sB-2zwvA:2.5","5n0sB-2zwvA:21.78"],["5ND3_B_TA1B601_1","TUBULIN BETA-2B CHAIN","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"GLU A  73;LEU A   3;ALA A  77;SER A  75;ARG A  28","None","1.19A","5nd3B-2zwvA:2.4","5nd3B-2zwvA:23.33"],["5X80_D_SALD201_1","UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887;UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",4,"GLY A 114;TYR A 117;VAL A 206;ARG A 113","None","1.37A","5x80C-2zwvA:undetectable;5x80D-2zwvA:undetectable","5x80C-2zwvA:20.53;5x80D-2zwvA:20.53"],["6A7J_A_TESA502_0","CYTOCHROME P450","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",4,"LEU A 137;LEU A 135;ALA A 126;ALA A 125","None","0.68A","6a7jA-2zwvA:undetectable","6a7jA-2zwvA:12.30"],["6EW0_B_TA1B501_1","TUBULIN BETA CHAIN","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"ASP A  51;LEU A 185;LEU A 203;ALA A  97;LEU A 182","None","1.12A","6ew0B-2zwvA:2.3","6ew0B-2zwvA:11.02"],["6EW0_D_TA1D501_1","TUBULIN BETA CHAIN","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"ASP A  51;LEU A 185;LEU A 203;ALA A  97;LEU A 182","None","1.12A","6ew0D-2zwvA:2.5","6ew0D-2zwvA:11.02"],["6EW0_H_TA1H501_1","TUBULIN BETA CHAIN","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"ASP A  51;LEU A 185;LEU A 203;ALA A  97;LEU A 182","None","1.12A","6ew0H-2zwvA:3.0","6ew0H-2zwvA:11.02"],["6EW0_I_TA1I501_1","TUBULIN BETA CHAIN","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"ASP A  51;LEU A 185;LEU A 203;ALA A  97;LEU A 182","None","1.12A","6ew0I-2zwvA:2.5","6ew0I-2zwvA:11.02"],["6IFT_A_SAMA301_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE A","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"GLY A 241;ALA A 246;ASP A 264;VAL A 289;PRO A 307","SAH A 376 (-3.1A);SAH A 376 (-3.3A);None;SAH A 376 (-4.0A);SAH A 376 ( 4.3A)","0.79A","6iftA-2zwvA:9.2","6iftA-2zwvA:21.84"],["6IFT_A_SAMA301_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE A","2zwv","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","Thermus thermophilus",5,"GLY A 241;GLY A 243;ALA A 246;ASP A 264;PRO A 307","SAH A 376 (-3.1A);SAH A 376 (-3.4A);SAH A 376 (-3.3A);None;SAH A 376 ( 4.3A)","0.57A","6iftA-2zwvA:9.2","6iftA-2zwvA:21.84"]]