SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zx0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2zx0 CSL3
(Oncorhynchus
keta) 		3 / 3 GLN A  43
THR A  45
ASN A  42
 None
 0.79A 3v4tE-2zx0A:
undetectable		 3v4tE-2zx0A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_B_GLYB709_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 2zx0 CSL3
(Oncorhynchus
keta) 		4 / 5 ASN A 126
ASP A 189
ARG A 129
ARG A 130
 None
 1.22A 6dwdB-2zx0A:
undetectable
6dwdD-2zx0A:
undetectable		 6dwdB-2zx0A:
14.86
6dwdD-2zx0A:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWJ_B_GLYB710_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 2zx0 CSL3
(Oncorhynchus
keta) 		4 / 5 ARG A 129
ARG A 130
ASN A 126
ASP A 189
 None
 1.30A 6dwjB-2zx0A:
undetectable
6dwjD-2zx0A:
undetectable		 6dwjB-2zx0A:
14.86
6dwjD-2zx0A:
14.86