SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zxq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1872_0
(FPRA)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 5 ASN A 936
ALA A 939
ASP A 496
GLU A 853
 None
 1.45A 1lqtA-2zxqA:
undetectable
1lqtB-2zxqA:
undetectable		 1lqtA-2zxqA:
15.41
1lqtB-2zxqA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1429_0
(FPRA)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 5 ASN A 936
ALA A 939
ASP A 496
GLU A 853
 None
 1.45A 1lquA-2zxqA:
undetectable
1lquB-2zxqA:
2.1		 1lquA-2zxqA:
15.41
1lquB-2zxqA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		3 / 3 ARG A 549
ASP A 496
ASN A 927
 None
 0.94A 1nbhA-2zxqA:
undetectable		 1nbhA-2zxqA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 10 THR A1245
LEU A1140
VAL A1146
VAL A1163
VAL A1250
 None
 1.32A 1o76A-2zxqA:
undetectable		 1o76A-2zxqA:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 7 TYR A 688
ASP A 774
ASP A 687
HIS A1304
 None
 1.16A 1t03A-2zxqA:
undetectable		 1t03A-2zxqA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 8 THR A1245
LEU A1140
VAL A1146
VAL A1163
VAL A1250
 None
 1.38A 1t86A-2zxqA:
undetectable		 1t86A-2zxqA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 9 THR A1245
LEU A1140
VAL A1146
VAL A1163
VAL A1250
 None
 1.34A 1t86B-2zxqA:
undetectable		 1t86B-2zxqA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 6 VAL A1163
LEU A1161
PHE A1109
SER A1099
 None
 0.92A 1wrlB-2zxqA:
undetectable		 1wrlB-2zxqA:
5.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		3 / 3 PHE A1247
ARG A1251
ASN A1218
 None
 0.84A 1xzxX-2zxqA:
undetectable		 1xzxX-2zxqA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA501_1
(CYTOCHROME P450 2B4)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 7 SER A 489
MET A 487
GLY A 543
THR A 805
 None
 1.04A 2bdmA-2zxqA:
undetectable		 2bdmA-2zxqA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 10 THR A1245
LEU A1140
VAL A1146
VAL A1163
VAL A1250
 None
 1.38A 2cp4A-2zxqA:
undetectable		 2cp4A-2zxqA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		6 / 12 LEU A 563
GLY A 515
VAL A 471
GLY A 613
VAL A 473
ILE A 517
 None
 1.46A 2f8gB-2zxqA:
undetectable		 2f8gB-2zxqA:
5.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 8 ASP A 910
TRP A 636
TYR A 902
HIS A 835
 None
 1.32A 2ha2A-2zxqA:
2.9		 2ha2A-2zxqA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 8 ASP A 910
TRP A 636
TYR A 902
HIS A 835
 None
 1.30A 2ha2B-2zxqA:
3.3		 2ha2B-2zxqA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 8 TYR A1087
ASP A 665
TYR A 907
TYR A1028
 None
 1.38A 2ha2B-2zxqA:
3.3		 2ha2B-2zxqA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 12 LEU A 470
ILE A 354
SER A 528
PRO A 592
VAL A 425
 None
 1.34A 2pnjB-2zxqA:
undetectable		 2pnjB-2zxqA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 12 VAL A1463
PHE A1506
ARG A1493
ILE A1496
ASN A1497
 None
 1.11A 2vdyA-2zxqA:
undetectable		 2vdyA-2zxqA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 6 LEU A 651
THR A 652
LEU A 695
ASP A 699
 None
 1.12A 2wm3A-2zxqA:
2.7		 2wm3A-2zxqA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 12 VAL A 964
SER A 912
THR A 908
GLY A 991
ALA A 989
 None
 1.15A 2x2iA-2zxqA:
6.8		 2x2iA-2zxqA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 12 VAL A 964
SER A 912
THR A 908
GLY A 991
ALA A 989
 None
 1.20A 2x2iC-2zxqA:
5.8		 2x2iC-2zxqA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 5 VAL A 576
TYR A 584
ASP A 758
SER A 797
 None
 1.35A 2x45A-2zxqA:
undetectable		 2x45A-2zxqA:
7.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1161_1
(ALLERGEN ARG R 1)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 5 VAL A 576
TYR A 584
ASP A 758
SER A 797
 None
 1.35A 2x45C-2zxqA:
undetectable		 2x45C-2zxqA:
7.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZQ9_A_CLSA11_1
(BETA-LACTAMASE
TOHO-1)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 4 GLU A1210
ARG A1168
ASN A1167
ASP A1166
 None
 1.26A 2zq9A-2zxqA:
undetectable		 2zq9A-2zxqA:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 12 ASN A1330
GLY A1435
ASP A1432
LEU A1392
TYR A1369
 None
 0.77A 2zw9A-2zxqA:
undetectable		 2zw9A-2zxqA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA1_0
(FERROCHELATASE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 11 LEU A 470
ILE A 354
SER A 528
PRO A 592
VAL A 425
 None
 1.40A 3aqiA-2zxqA:
0.2		 3aqiA-2zxqA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB6_0
(FERROCHELATASE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 12 LEU A 470
ILE A 354
SER A 528
PRO A 592
VAL A 425
 None
 1.05A 3aqiB-2zxqA:
undetectable		 3aqiB-2zxqA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 4 SER A 825
GLY A 824
GLY A 544
GLY A 792
 None
 0.71A 3bogB-2zxqA:
undetectable
3bogD-2zxqA:
undetectable		 3bogB-2zxqA:
undetectable
3bogD-2zxqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 4 SER A1169
GLY A1171
GLY A1242
GLY A1142
 None
 0.85A 3bogB-2zxqA:
undetectable
3bogD-2zxqA:
undetectable		 3bogB-2zxqA:
undetectable
3bogD-2zxqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 8 GLY A 544
GLY A 543
GLY A 792
THR A 821
 None
 0.51A 3d41A-2zxqA:
undetectable		 3d41A-2zxqA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 7 TYR A 873
ASN A 886
LEU A 840
ASP A 839
 None
 1.19A 3lslA-2zxqA:
undetectable
3lslD-2zxqA:
undetectable		 3lslA-2zxqA:
12.39
3lslD-2zxqA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 7 TYR A 873
ASN A 886
LEU A 840
ASP A 839
 None
 1.21A 3lslA-2zxqA:
undetectable
3lslD-2zxqA:
undetectable		 3lslA-2zxqA:
12.39
3lslD-2zxqA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 6 TYR A 873
ASN A 886
LEU A 840
ASP A 839
 None
 1.26A 3lslG-2zxqA:
undetectable		 3lslG-2zxqA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 11 LEU A 633
GLN A 917
ILE A 916
PHE A 919
THR A 820
 None
 1.40A 3qelA-2zxqA:
undetectable
3qelB-2zxqA:
undetectable		 3qelA-2zxqA:
15.01
3qelB-2zxqA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 9 THR A1272
ASN A1273
GLY A1274
ASP A1442
ASP A1322
 None
MPD  A1695 (-4.4A)
MPD  A1695 ( 3.2A)
MN  A   4 (-2.3A)
None
 1.47A 3sfuA-2zxqA:
undetectable		 3sfuA-2zxqA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_B_RBVB601_1
(RNA POLYMERASE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 9 THR A1272
ASN A1273
GLY A1274
ASP A1442
ASP A1322
 None
MPD  A1695 (-4.4A)
MPD  A1695 ( 3.2A)
MN  A   4 (-2.3A)
None
 1.47A 3sfuB-2zxqA:
undetectable		 3sfuB-2zxqA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA5_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		3 / 3 LYS A 920
SER A 627
GLN A 862
 None
 1.38A 3si7A-2zxqA:
undetectable		 3si7A-2zxqA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_A_MIYA2001_1
(TETX2 PROTEIN)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 11 GLN A 753
GLY A 747
PRO A 726
PHE A 731
GLY A 684
 None
 1.29A 3v3nA-2zxqA:
undetectable		 3v3nA-2zxqA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		3 / 3 GLN A 593
THR A 439
ASN A 437
 None
 0.90A 3v4tE-2zxqA:
0.8		 3v4tE-2zxqA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 12 LEU A 470
ILE A 354
SER A 528
PRO A 592
VAL A 425
 None
 1.05A 3w1wA-2zxqA:
undetectable		 3w1wA-2zxqA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 12 VAL A1463
PHE A1506
ARG A1493
ILE A1496
ASN A1497
 None
 1.09A 4c49B-2zxqA:
undetectable		 4c49B-2zxqA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 12 VAL A1463
PHE A1506
ARG A1493
ILE A1496
ASN A1497
 None
 1.08A 4c49C-2zxqA:
undetectable		 4c49C-2zxqA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 12 VAL A1463
PHE A1506
ARG A1493
ILE A1496
ASN A1497
 None
 1.09A 4c49D-2zxqA:
undetectable		 4c49D-2zxqA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 8 ASN A 926
LYS A 955
ASN A 603
THR A 922
 None
None
MN  A   1 (-3.0A)
None
 1.45A 4d1yA-2zxqA:
undetectable
4d1yB-2zxqA:
undetectable		 4d1yA-2zxqA:
9.74
4d1yB-2zxqA:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 8 GLN A 611
LYS A 955
ASN A 603
THR A 922
 None
None
MN  A   1 (-3.0A)
None
 1.34A 4d1yA-2zxqA:
undetectable
4d1yB-2zxqA:
undetectable		 4d1yA-2zxqA:
9.74
4d1yB-2zxqA:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 6 ARG A 549
TYR A 617
TYR A 514
LEU A 858
 None
 1.39A 4f8yA-2zxqA:
undetectable
4f8yB-2zxqA:
undetectable		 4f8yA-2zxqA:
10.09
4f8yB-2zxqA:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_D_VK3D202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 5 ARG A 549
TYR A 617
TYR A 514
LEU A 858
 None
 1.32A 4f8yC-2zxqA:
0.0
4f8yD-2zxqA:
undetectable		 4f8yC-2zxqA:
10.09
4f8yD-2zxqA:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 12 LEU A 522
GLY A 525
GLY A 613
ILE A 598
VAL A 550
 None
 1.04A 4gc9A-2zxqA:
undetectable		 4gc9A-2zxqA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 5 PHE A 516
PHE A 482
LEU A 930
PRO A 494
 None
 1.12A 4o8zA-2zxqA:
undetectable		 4o8zA-2zxqA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		3 / 3 ASP A 789
TYR A 787
TRP A 823
 None
None
MPD  A1696 (-4.1A)
 1.43A 4p7nA-2zxqA:
2.6		 4p7nA-2zxqA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSS_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 12 LEU A 591
ALA A 590
ILE A 423
LEU A 463
ILE A 460
 None
 0.91A 4pssA-2zxqA:
undetectable		 4pssA-2zxqA:
7.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		3 / 3 GLN A 862
HIS A 861
ARG A 618
 None
 1.25A 4qyqA-2zxqA:
undetectable		 4qyqA-2zxqA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		3 / 3 GLN A 862
HIS A 861
ARG A 618
 None
 1.22A 4qyqB-2zxqA:
undetectable		 4qyqB-2zxqA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_A_1N1A601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		3 / 3 MET A1102
ASP A1248
PHE A1247
 None
MN  A   3 (-2.2A)
None
 1.04A 4xeyA-2zxqA:
0.0		 4xeyA-2zxqA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_B_1N1B601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		3 / 3 MET A1102
ASP A1248
PHE A1247
 None
MN  A   3 (-2.2A)
None
 1.04A 4xeyB-2zxqA:
undetectable		 4xeyB-2zxqA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 12 GLY A 525
TYR A 514
ILE A 517
SER A 518
TRP A 610
 None
 1.36A 4xudA-2zxqA:
undetectable		 4xudA-2zxqA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 12 GLY A1142
LEU A1116
GLY A1108
LEU A1235
THR A1141
 None
None
MN  A   3 (-3.8A)
None
None
 1.17A 4ze2A-2zxqA:
undetectable		 4ze2A-2zxqA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 7 VAL A1233
PHE A1247
VAL A1250
ILE A1252
 None
 0.77A 5bmvC-2zxqA:
undetectable		 5bmvC-2zxqA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_1
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		3 / 3 ARG A1139
LYS A1127
GLU A1129
 None
 0.66A 5d0yA-2zxqA:
undetectable		 5d0yA-2zxqA:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		3 / 3 GLU A 800
TRP A 823
ASN A 720
 None
MPD  A1696 (-4.1A)
None
 0.80A 5dv4A-2zxqA:
undetectable		 5dv4A-2zxqA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 12 GLY A 892
ILE A 638
ILE A1198
ASN A1204
PHE A 642
 None
 1.08A 5fa8A-2zxqA:
undetectable		 5fa8A-2zxqA:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 12 ILE A 620
HIS A 435
PHE A 516
ALA A 614
MET A 350
 None
 1.24A 5iwuA-2zxqA:
0.5		 5iwuA-2zxqA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 5 GLY A1404
THR A1403
GLY A1281
LEU A1271
 None
 0.77A 5jlcA-2zxqA:
undetectable		 5jlcA-2zxqA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC0_A_RBFA303_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 12 ASP A1442
ASN A1273
ALA A1279
ASN A1255
PHE A1222
 MN  A   4 (-2.3A)
MPD  A1695 (-4.4A)
None
None
None
 1.35A 5kc0A-2zxqA:
0.0		 5kc0A-2zxqA:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 12 ASP A1442
ASN A1273
ALA A1279
ASN A1255
PHE A1222
 MN  A   4 (-2.3A)
MPD  A1695 (-4.4A)
None
None
None
 1.31A 5kc4A-2zxqA:
undetectable		 5kc4A-2zxqA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		3 / 3 LYS A 674
HIS A 681
HIS A 718
 None
 1.12A 5oexA-2zxqA:
undetectable		 5oexA-2zxqA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		3 / 3 LYS A 674
HIS A 681
HIS A 718
 None
 1.11A 5oexB-2zxqA:
1.9		 5oexB-2zxqA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		3 / 3 LYS A 674
HIS A 681
HIS A 718
 None
 1.11A 5oexC-2zxqA:
1.8		 5oexC-2zxqA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		3 / 3 LYS A 674
HIS A 681
HIS A 718
 None
 1.10A 5oexD-2zxqA:
undetectable		 5oexD-2zxqA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_1
(REGULATORY PROTEIN
TETR)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 7 GLY A 868
TYR A1006
ASP A 910
ASP A 839
 None
 1.07A 5vlmE-2zxqA:
2.8		 5vlmE-2zxqA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_0
(REGULATORY PROTEIN
TETR)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 12 ALA A 713
SER A 670
LEU A 633
TYR A1028
VAL A 660
 None
 1.45A 5vlmH-2zxqA:
undetectable		 5vlmH-2zxqA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW4_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 9 SER A1426
GLY A1434
ALA A1430
GLY A1435
SER A1365
 None
 1.17A 5vw4A-2zxqA:
undetectable		 5vw4A-2zxqA:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA901_0
(MRNA CAPPING ENZYME
P5)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 11 VAL A 779
GLY A 780
SER A 776
LEU A 775
ASN A 815
 None
 1.13A 5x6yA-2zxqA:
undetectable		 5x6yA-2zxqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_A_SALA201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 5 VAL A 993
ARG A 977
PRO A 871
GLY A 996
 None
 1.44A 5x80A-2zxqA:
undetectable
5x80B-2zxqA:
undetectable		 5x80A-2zxqA:
9.57
5x80B-2zxqA:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 5 PRO A 871
GLY A 996
VAL A 993
ARG A 977
 None
 1.44A 5x80C-2zxqA:
undetectable
5x80D-2zxqA:
undetectable		 5x80C-2zxqA:
9.57
5x80D-2zxqA:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AF6_A_GLYA507_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		3 / 3 TYR A 688
HIS A 685
MET A 724
 None
 1.23A 6af6A-2zxqA:
3.6		 6af6A-2zxqA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		4 / 5 VAL A 925
TRP A 924
PRO A 928
THR A 953
 None
 1.38A 6cduA-2zxqA:
undetectable
6cduB-2zxqA:
undetectable		 6cduA-2zxqA:
12.64
6cduB-2zxqA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_A_SAMA401_0
(O-METHYLTRANSFERASE)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		5 / 12 ARG A 979
ALA A 879
GLY A 996
VAL A 992
TRP A1030
 None
 1.21A 6clxA-2zxqA:
undetectable		 6clxA-2zxqA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE
(Bifidobacterium
longum) 		3 / 3 ASP A1319
ASP A1313
ASN A 739
 None
 0.78A 6gngB-2zxqA:
undetectable		 6gngB-2zxqA:
18.92