SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zxx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 2zxx DNA REPLICATION
FACTOR CDT1
(Mus
musculus) 		3 / 3 GLN C 191
HIS C 187
PRO C 200
 None
 0.93A 1d8cA-2zxxC:
undetectable		 1d8cA-2zxxC:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2zxx DNA REPLICATION
FACTOR CDT1
(Mus
musculus) 		4 / 7 LEU C 199
GLN C 191
LEU C 314
PHE C 310
 None
 0.95A 1v55P-2zxxC:
undetectable
1v55W-2zxxC:
undetectable		 1v55P-2zxxC:
20.21
1v55W-2zxxC:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA502_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 2zxx DNA REPLICATION
FACTOR CDT1
(Mus
musculus) 		3 / 3 LEU C 197
HIS C 322
LYS C 319
 None
 1.06A 1y7iA-2zxxC:
undetectable		 1y7iA-2zxxC:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2zxx DNA REPLICATION
FACTOR CDT1
(Mus
musculus) 		4 / 7 LEU C 199
GLN C 191
LEU C 314
PHE C 310
 None
 0.92A 2dysC-2zxxC:
undetectable
2dysJ-2zxxC:
undetectable		 2dysC-2zxxC:
20.21
2dysJ-2zxxC:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2zxx DNA REPLICATION
FACTOR CDT1
(Mus
musculus) 		4 / 7 LEU C 199
GLN C 191
LEU C 314
PHE C 310
 None
 0.98A 2eijP-2zxxC:
undetectable
2eijW-2zxxC:
undetectable		 2eijP-2zxxC:
20.21
2eijW-2zxxC:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2zxx DNA REPLICATION
FACTOR CDT1
(Mus
musculus) 		4 / 8 LEU C 199
GLN C 191
LEU C 314
PHE C 310
 None
 0.95A 2eilP-2zxxC:
undetectable
2eilW-2zxxC:
undetectable		 2eilP-2zxxC:
20.21
2eilW-2zxxC:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2zxx DNA REPLICATION
FACTOR CDT1
(Mus
musculus) 		4 / 7 LEU C 298
LEU C 303
GLU C 225
ARG C 223
 None
 1.06A 2jn3A-2zxxC:
undetectable		 2jn3A-2zxxC:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2zxx DNA REPLICATION
FACTOR CDT1
(Mus
musculus) 		4 / 7 LEU C 199
GLN C 191
LEU C 314
PHE C 310
 None
 1.00A 2zxwC-2zxxC:
undetectable
2zxwJ-2zxxC:
undetectable		 2zxwC-2zxxC:
20.21
2zxwJ-2zxxC:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2zxx DNA REPLICATION
FACTOR CDT1
(Mus
musculus) 		4 / 7 LEU C 199
GLN C 191
LEU C 314
PHE C 310
 None
 0.93A 3x2qC-2zxxC:
undetectable
3x2qJ-2zxxC:
undetectable		 3x2qC-2zxxC:
20.21
3x2qJ-2zxxC:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 2zxx DNA REPLICATION
FACTOR CDT1
(Mus
musculus) 		5 / 12 PHE C 347
LEU C 314
VAL C 207
GLN C 204
ALA C 188
 None
 1.50A 4a84A-2zxxC:
undetectable		 4a84A-2zxxC:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2zxx GEMININ
(Mus
musculus) 		4 / 7 ASN A 114
GLU A 113
GLU A 109
TYR A 108
 None
 1.27A 4mj8C-2zxxA:
undetectable		 4mj8C-2zxxA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2zxx GEMININ
(Mus
musculus) 		4 / 7 ASN A 114
GLU A 113
GLU A 109
TYR A 108
 None
 1.12A 4r87I-2zxxA:
undetectable		 4r87I-2zxxA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 2zxx DNA REPLICATION
FACTOR CDT1
(Mus
musculus) 		3 / 3 LEU C 314
VAL C 349
ASP C 350
 None
 0.63A 4y8wC-2zxxC:
undetectable		 4y8wC-2zxxC:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2zxx DNA REPLICATION
FACTOR CDT1
(Mus
musculus) 		4 / 7 LEU C 199
GLN C 191
LEU C 314
PHE C 310
 None
 0.97A 5b1aC-2zxxC:
undetectable
5b1aJ-2zxxC:
undetectable		 5b1aC-2zxxC:
20.21
5b1aJ-2zxxC:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2zxx DNA REPLICATION
FACTOR CDT1
(Mus
musculus) 		4 / 7 LEU C 199
GLN C 191
LEU C 314
PHE C 310
 None
 0.92A 5iy5C-2zxxC:
undetectable
5iy5J-2zxxC:
undetectable		 5iy5C-2zxxC:
19.86
5iy5J-2zxxC:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 2zxx DNA REPLICATION
FACTOR CDT1
(Mus
musculus) 		5 / 12 VAL C 349
ASP C 350
THR C 254
ARG C 311
LEU C 206
 None
 1.39A 5m50B-2zxxC:
undetectable		 5m50B-2zxxC:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2zxx DNA REPLICATION
FACTOR CDT1
(Mus
musculus) 		4 / 7 LEU C 199
GLN C 191
LEU C 314
PHE C 310
 None
 0.86A 5z84C-2zxxC:
undetectable
5z84J-2zxxC:
undetectable		 5z84C-2zxxC:
20.21
5z84J-2zxxC:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2zxx DNA REPLICATION
FACTOR CDT1
(Mus
musculus) 		4 / 7 LEU C 199
GLN C 191
LEU C 314
PHE C 310
 None
 0.88A 5z85C-2zxxC:
undetectable
5z85J-2zxxC:
undetectable		 5z85C-2zxxC:
20.21
5z85J-2zxxC:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2zxx DNA REPLICATION
FACTOR CDT1
(Mus
musculus) 		4 / 7 LEU C 199
GLN C 191
LEU C 314
PHE C 310
 None
 0.83A 5zcoC-2zxxC:
undetectable
5zcoJ-2zxxC:
undetectable		 5zcoC-2zxxC:
20.21
5zcoJ-2zxxC:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2zxx DNA REPLICATION
FACTOR CDT1
(Mus
musculus) 		4 / 7 LEU C 199
GLN C 191
LEU C 314
PHE C 310
 None
 0.89A 5zcqP-2zxxC:
undetectable
5zcqW-2zxxC:
undetectable		 5zcqP-2zxxC:
20.21
5zcqW-2zxxC:
14.07