SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zy2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9H_A_RAPA108_1
(FKBP12.6)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 12 ASP A 286
PHE A 204
ILE A 210
ILE A 181
PHE A 250
 PLP  A 900 (-3.2A)
PLP  A 900 (-4.2A)
None
None
None
 0.95A 1c9hA-2zy2A:
undetectable		 1c9hA-2zy2A:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.27A 1c9sJ-2zy2A:
undetectable
1c9sK-2zy2A:
undetectable		 1c9sJ-2zy2A:
8.61
1c9sK-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FAP_A_RAPA108_1
(FK506-BINDING
PROTEIN)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 12 ASP A 286
PHE A 204
ILE A 210
ILE A 181
PHE A 250
 PLP  A 900 (-3.2A)
PLP  A 900 (-4.2A)
None
None
None
 0.97A 1fapA-2zy2A:
undetectable		 1fapA-2zy2A:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 12 ASP A 286
PHE A 204
ILE A 210
ILE A 181
PHE A 250
 PLP  A 900 (-3.2A)
PLP  A 900 (-4.2A)
None
None
None
 1.07A 1fklA-2zy2A:
undetectable		 1fklA-2zy2A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.30A 1gtfC-2zy2A:
undetectable
1gtfD-2zy2A:
undetectable		 1gtfC-2zy2A:
8.61
1gtfD-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.25A 1gtfG-2zy2A:
undetectable
1gtfH-2zy2A:
undetectable		 1gtfG-2zy2A:
8.61
1gtfH-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.26A 1gtfH-2zy2A:
undetectable
1gtfI-2zy2A:
undetectable		 1gtfH-2zy2A:
8.61
1gtfI-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.27A 1gtfI-2zy2A:
undetectable
1gtfJ-2zy2A:
undetectable		 1gtfI-2zy2A:
8.61
1gtfJ-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 1gtfP-2zy2A:
undetectable
1gtfQ-2zy2A:
undetectable		 1gtfP-2zy2A:
8.61
1gtfQ-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.27A 1gtfT-2zy2A:
undetectable
1gtfU-2zy2A:
undetectable		 1gtfT-2zy2A:
8.61
1gtfU-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 11 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 1gtfU-2zy2A:
undetectable
1gtfV-2zy2A:
undetectable		 1gtfU-2zy2A:
8.61
1gtfV-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.28A 1gtfL-2zy2A:
undetectable
1gtfV-2zy2A:
undetectable		 1gtfL-2zy2A:
8.61
1gtfV-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.30A 1gtnG-2zy2A:
undetectable
1gtnH-2zy2A:
undetectable		 1gtnG-2zy2A:
8.61
1gtnH-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.32A 1gtnN-2zy2A:
undetectable
1gtnO-2zy2A:
undetectable		 1gtnN-2zy2A:
8.61
1gtnO-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 8 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.28A 1gtnP-2zy2A:
undetectable
1gtnQ-2zy2A:
undetectable		 1gtnP-2zy2A:
8.61
1gtnQ-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K4T_D_TTCD990_1
(DNA TOPOISOMERASE I)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		4 / 5 GLU A 124
ARG A 139
LYS A 365
ASP A 368
 None
 1.46A 1k4tA-2zy2A:
undetectable		 1k4tA-2zy2A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.26A 1utdA-2zy2A:
undetectable
1utdB-2zy2A:
undetectable		 1utdA-2zy2A:
8.61
1utdB-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 1utdC-2zy2A:
undetectable
1utdD-2zy2A:
undetectable		 1utdC-2zy2A:
8.61
1utdD-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.27A 1utdG-2zy2A:
undetectable
1utdH-2zy2A:
undetectable		 1utdG-2zy2A:
8.61
1utdH-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 11 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.28A 1utdM-2zy2A:
undetectable
1utdN-2zy2A:
undetectable		 1utdM-2zy2A:
8.61
1utdN-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.26A 1utdN-2zy2A:
undetectable
1utdO-2zy2A:
undetectable		 1utdN-2zy2A:
8.61
1utdO-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.31A 1utdQ-2zy2A:
undetectable
1utdR-2zy2A:
undetectable		 1utdQ-2zy2A:
8.61
1utdR-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.28A 1utdR-2zy2A:
undetectable
1utdS-2zy2A:
undetectable		 1utdR-2zy2A:
8.61
1utdS-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 12 PRO A 431
ILE A 481
VAL A 475
ILE A 444
LEU A 472
 None
 1.10A 1z9hD-2zy2A:
2.2		 1z9hD-2zy2A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_A_GBNA2414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		4 / 8 GLY A 325
THR A 175
ALA A 176
ALA A 177
 None
PLP  A 900 (-3.8A)
None
None
 0.59A 2ej3A-2zy2A:
undetectable		 2ej3A-2zy2A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_B_GBNB914_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 325
GLY A 174
THR A 175
ALA A 176
ALA A 177
 None
PLP  A 900 (-3.5A)
PLP  A 900 (-3.8A)
None
None
 0.81A 2ej3B-2zy2A:
undetectable		 2ej3B-2zy2A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_C_GBNC1414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 8 GLY A 325
GLY A 174
THR A 175
ALA A 176
ALA A 177
 None
PLP  A 900 (-3.5A)
PLP  A 900 (-3.8A)
None
None
 0.81A 2ej3C-2zy2A:
undetectable		 2ej3C-2zy2A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_FFOB505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 12 GLY A 480
SER A  25
ALA A  24
SER A 499
GLY A  38
 None
 0.99A 2vmyA-2zy2A:
9.4		 2vmyA-2zy2A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WQ5_A_MIYA1120_1
(PHOSPHOLIPASE A2,
ACIDIC)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		4 / 7 LEU A 284
ALA A 177
PHE A 250
PHE A 249
 None
 0.95A 2wq5A-2zy2A:
undetectable		 2wq5A-2zy2A:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 8 SER A 499
PHE A 317
GLY A 318
ASN A  41
ALA A  44
 None
 1.28A 3aodA-2zy2A:
2.4		 3aodA-2zy2A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CWK_A_REAA300_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 12 LEU A  80
ALA A 120
VAL A 136
THR A 142
VAL A 143
 None
 1.23A 3cwkA-2zy2A:
undetectable		 3cwkA-2zy2A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CWK_A_REAA300_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 12 LEU A  80
LEU A 122
ALA A 120
THR A 142
VAL A 143
 None
 1.25A 3cwkA-2zy2A:
undetectable		 3cwkA-2zy2A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_2
(DIHYDROFOLATE
REDUCTASE)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		3 / 3 ARG A 265
ILE A 273
THR A 307
 None
 0.70A 3ia4D-2zy2A:
undetectable		 3ia4D-2zy2A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC800_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		3 / 3 ASP A 373
ARG A 369
ALA A 372
 None
 0.63A 3mbgC-2zy2A:
1.4		 3mbgC-2zy2A:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_C_PM6C1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		4 / 6 GLU A 172
PHE A 169
ALA A 176
ALA A 177
 None
 1.22A 3ns1C-2zy2A:
undetectable		 3ns1C-2zy2A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGL_A_RZXA257_1
(CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		4 / 7 PHE A 313
VAL A 326
ILE A 152
SER A 144
 None
 0.98A 3pglA-2zy2A:
undetectable		 3pglA-2zy2A:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		3 / 3 GLY A 131
THR A 387
ASN A 133
 None
 0.69A 3v4tD-2zy2A:
undetectable		 3v4tD-2zy2A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 12 CYH A 251
HIS A 224
ILE A 223
LEU A 238
MET A 262
 None
 1.39A 3vn2A-2zy2A:
undetectable		 3vn2A-2zy2A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		3 / 3 ASN A 306
LEU A 185
PHE A 249
 None
 0.77A 4dajB-2zy2A:
undetectable		 4dajB-2zy2A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRH_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 12 ASP A 286
PHE A 204
ILE A 210
ILE A 181
PHE A 250
 PLP  A 900 (-3.2A)
PLP  A 900 (-4.2A)
None
None
None
 1.11A 4drhA-2zy2A:
undetectable		 4drhA-2zy2A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRH_D_RAPD201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 12 ASP A 286
PHE A 204
ILE A 210
ILE A 181
PHE A 250
 PLP  A 900 (-3.2A)
PLP  A 900 (-4.2A)
None
None
None
 1.12A 4drhD-2zy2A:
undetectable		 4drhD-2zy2A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 11 ASP A 286
PHE A 204
ILE A 210
ILE A 181
PHE A 250
 PLP  A 900 (-3.2A)
PLP  A 900 (-4.2A)
None
None
None
 1.03A 4driA-2zy2A:
undetectable		 4driA-2zy2A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 11 ASP A 286
PHE A 204
ILE A 210
ILE A 181
PHE A 250
 PLP  A 900 (-3.2A)
PLP  A 900 (-4.2A)
None
None
None
 1.01A 4drjA-2zy2A:
undetectable		 4drjA-2zy2A:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		4 / 4 PRO A 118
LEU A 122
ILE A  83
ARG A  86
 None
 1.42A 4f4dA-2zy2A:
undetectable		 4f4dA-2zy2A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		3 / 3 TYR A 180
ARG A 375
SER A 374
 None
 1.06A 4khpI-2zy2A:
undetectable
4khpJ-2zy2A:
undetectable		 4khpI-2zy2A:
14.78
4khpJ-2zy2A:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		3 / 3 ASP A 263
VAL A 438
ASN A 229
 None
 0.59A 4lmnA-2zy2A:
undetectable		 4lmnA-2zy2A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		4 / 8 LEU A 114
VAL A 394
VAL A 143
LEU A 401
 None
 1.18A 4q0bA-2zy2A:
undetectable		 4q0bA-2zy2A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QT2_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 ASP A 286
PHE A 204
ILE A 210
ILE A 181
PHE A 250
 PLP  A 900 (-3.2A)
PLP  A 900 (-4.2A)
None
None
None
 1.09A 4qt2A-2zy2A:
undetectable		 4qt2A-2zy2A:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 ASP A 286
PHE A 204
ILE A 210
ILE A 181
PHE A 250
 PLP  A 900 (-3.2A)
PLP  A 900 (-4.2A)
None
None
None
 1.05A 4qt3A-2zy2A:
undetectable		 4qt3A-2zy2A:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 GLU A 172
LEU A 168
VAL A 371
LEU A 370
ILE A 367
 None
 1.20A 4r38C-2zy2A:
undetectable		 4r38C-2zy2A:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 12 LEU A 130
GLU A  84
ALA A  60
PHE A  57
LEU A 103
 None
 1.15A 4retA-2zy2A:
undetectable		 4retA-2zy2A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 12 LEU A 130
GLU A  84
ALA A  60
PHE A  57
LEU A 103
 None
 1.15A 4retC-2zy2A:
undetectable		 4retC-2zy2A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1006_1
(SERUM ALBUMIN)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		4 / 7 ILE A 511
LEU A 515
TYR A 424
GLY A 496
 None
 0.97A 4z69A-2zy2A:
undetectable		 4z69A-2zy2A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_C7HA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		4 / 5 TYR A 151
GLY A 290
TYR A 316
GLY A 318
 None
 1.01A 5ayfA-2zy2A:
undetectable		 5ayfA-2zy2A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_P_EVPP2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		4 / 6 SER A 255
ASP A 445
ARG A 493
GLY A 486
 None
 0.90A 5cdnT-2zy2A:
undetectable
5cdnU-2zy2A:
undetectable		 5cdnT-2zy2A:
23.72
5cdnU-2zy2A:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		4 / 8 PHE A 396
ALA A 400
PRO A  47
LEU A 395
 None
 1.18A 5dzkd-2zy2A:
1.9
5dzkr-2zy2A:
undetectable		 5dzkd-2zy2A:
17.86
5dzkr-2zy2A:
1.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.27A 5eeuE-2zy2A:
undetectable
5eeuF-2zy2A:
undetectable		 5eeuE-2zy2A:
8.61
5eeuF-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.25A 5eeuG-2zy2A:
undetectable
5eeuH-2zy2A:
undetectable		 5eeuG-2zy2A:
8.61
5eeuH-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.27A 5eeuJ-2zy2A:
undetectable
5eeuK-2zy2A:
undetectable		 5eeuJ-2zy2A:
8.61
5eeuK-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.28A 5eeuN-2zy2A:
undetectable
5eeuO-2zy2A:
undetectable		 5eeuN-2zy2A:
8.61
5eeuO-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.28A 5eeuP-2zy2A:
undetectable
5eeuQ-2zy2A:
undetectable		 5eeuP-2zy2A:
8.61
5eeuQ-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 5eeuR-2zy2A:
undetectable
5eeuS-2zy2A:
undetectable		 5eeuR-2zy2A:
8.61
5eeuS-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.26A 5eeuS-2zy2A:
undetectable
5eeuT-2zy2A:
undetectable		 5eeuS-2zy2A:
8.61
5eeuT-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.30A 5eeuT-2zy2A:
undetectable
5eeuU-2zy2A:
undetectable		 5eeuT-2zy2A:
8.61
5eeuU-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.26A 5eeuU-2zy2A:
undetectable
5eeuV-2zy2A:
undetectable		 5eeuU-2zy2A:
8.61
5eeuV-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.27A 5eevE-2zy2A:
undetectable
5eevF-2zy2A:
undetectable		 5eevE-2zy2A:
8.61
5eevF-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.25A 5eevG-2zy2A:
undetectable
5eevH-2zy2A:
undetectable		 5eevG-2zy2A:
8.61
5eevH-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.26A 5eevJ-2zy2A:
undetectable
5eevK-2zy2A:
undetectable		 5eevJ-2zy2A:
8.61
5eevK-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 5eevN-2zy2A:
undetectable
5eevO-2zy2A:
undetectable		 5eevN-2zy2A:
8.61
5eevO-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.28A 5eevP-2zy2A:
undetectable
5eevQ-2zy2A:
undetectable		 5eevP-2zy2A:
8.61
5eevQ-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 5eevR-2zy2A:
undetectable
5eevS-2zy2A:
undetectable		 5eevR-2zy2A:
8.61
5eevS-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.27A 5eevS-2zy2A:
undetectable
5eevT-2zy2A:
undetectable		 5eevS-2zy2A:
8.61
5eevT-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.30A 5eevT-2zy2A:
undetectable
5eevU-2zy2A:
undetectable		 5eevT-2zy2A:
8.61
5eevU-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.27A 5eevU-2zy2A:
undetectable
5eevV-2zy2A:
undetectable		 5eevU-2zy2A:
8.61
5eevV-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.27A 5eewE-2zy2A:
undetectable
5eewF-2zy2A:
undetectable		 5eewE-2zy2A:
8.61
5eewF-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.25A 5eewG-2zy2A:
undetectable
5eewH-2zy2A:
undetectable		 5eewG-2zy2A:
8.61
5eewH-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.26A 5eewJ-2zy2A:
undetectable
5eewK-2zy2A:
undetectable		 5eewJ-2zy2A:
8.61
5eewK-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.28A 5eewN-2zy2A:
undetectable
5eewO-2zy2A:
undetectable		 5eewN-2zy2A:
8.61
5eewO-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.28A 5eewP-2zy2A:
undetectable
5eewQ-2zy2A:
undetectable		 5eewP-2zy2A:
8.61
5eewQ-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 5eewR-2zy2A:
undetectable
5eewS-2zy2A:
undetectable		 5eewR-2zy2A:
8.61
5eewS-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.27A 5eewS-2zy2A:
undetectable
5eewT-2zy2A:
undetectable		 5eewS-2zy2A:
8.61
5eewT-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.30A 5eewT-2zy2A:
undetectable
5eewU-2zy2A:
undetectable		 5eewT-2zy2A:
8.61
5eewU-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.27A 5eewU-2zy2A:
undetectable
5eewV-2zy2A:
undetectable		 5eewU-2zy2A:
8.61
5eewV-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.27A 5eexE-2zy2A:
undetectable
5eexF-2zy2A:
undetectable		 5eexE-2zy2A:
8.61
5eexF-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.25A 5eexG-2zy2A:
undetectable
5eexH-2zy2A:
undetectable		 5eexG-2zy2A:
8.61
5eexH-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 11 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.26A 5eexI-2zy2A:
undetectable
5eexJ-2zy2A:
undetectable		 5eexI-2zy2A:
8.61
5eexJ-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.27A 5eexJ-2zy2A:
undetectable
5eexK-2zy2A:
undetectable		 5eexJ-2zy2A:
8.61
5eexK-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 5eexN-2zy2A:
undetectable
5eexO-2zy2A:
undetectable		 5eexN-2zy2A:
8.61
5eexO-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.28A 5eexP-2zy2A:
undetectable
5eexQ-2zy2A:
undetectable		 5eexP-2zy2A:
8.61
5eexQ-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 5eexQ-2zy2A:
undetectable
5eexR-2zy2A:
undetectable		 5eexQ-2zy2A:
8.61
5eexR-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 5eexR-2zy2A:
undetectable
5eexS-2zy2A:
undetectable		 5eexR-2zy2A:
8.61
5eexS-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.27A 5eexS-2zy2A:
undetectable
5eexT-2zy2A:
undetectable		 5eexS-2zy2A:
8.61
5eexT-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.30A 5eexT-2zy2A:
undetectable
5eexU-2zy2A:
undetectable		 5eexT-2zy2A:
8.61
5eexU-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.27A 5eexU-2zy2A:
undetectable
5eexV-2zy2A:
undetectable		 5eexU-2zy2A:
8.61
5eexV-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.27A 5eeyE-2zy2A:
undetectable
5eeyF-2zy2A:
undetectable		 5eeyE-2zy2A:
8.61
5eeyF-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.25A 5eeyG-2zy2A:
undetectable
5eeyH-2zy2A:
undetectable		 5eeyG-2zy2A:
8.61
5eeyH-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 11 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.26A 5eeyI-2zy2A:
undetectable
5eeyJ-2zy2A:
undetectable		 5eeyI-2zy2A:
8.61
5eeyJ-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.27A 5eeyJ-2zy2A:
undetectable
5eeyK-2zy2A:
undetectable		 5eeyJ-2zy2A:
8.61
5eeyK-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 5eeyN-2zy2A:
undetectable
5eeyO-2zy2A:
undetectable		 5eeyN-2zy2A:
8.61
5eeyO-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.28A 5eeyP-2zy2A:
undetectable
5eeyQ-2zy2A:
undetectable		 5eeyP-2zy2A:
8.61
5eeyQ-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 5eeyQ-2zy2A:
undetectable
5eeyR-2zy2A:
undetectable		 5eeyQ-2zy2A:
8.61
5eeyR-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 5eeyR-2zy2A:
undetectable
5eeyS-2zy2A:
undetectable		 5eeyR-2zy2A:
8.61
5eeyS-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.27A 5eeyS-2zy2A:
undetectable
5eeyT-2zy2A:
undetectable		 5eeyS-2zy2A:
8.61
5eeyT-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.30A 5eeyT-2zy2A:
undetectable
5eeyU-2zy2A:
undetectable		 5eeyT-2zy2A:
8.61
5eeyU-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.27A 5eeyU-2zy2A:
undetectable
5eeyV-2zy2A:
undetectable		 5eeyU-2zy2A:
8.61
5eeyV-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.27A 5eezE-2zy2A:
undetectable
5eezF-2zy2A:
undetectable		 5eezE-2zy2A:
8.61
5eezF-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.25A 5eezG-2zy2A:
undetectable
5eezH-2zy2A:
undetectable		 5eezG-2zy2A:
8.61
5eezH-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 11 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.26A 5eezI-2zy2A:
undetectable
5eezJ-2zy2A:
undetectable		 5eezI-2zy2A:
8.61
5eezJ-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.27A 5eezJ-2zy2A:
undetectable
5eezK-2zy2A:
undetectable		 5eezJ-2zy2A:
8.61
5eezK-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 5eezN-2zy2A:
undetectable
5eezO-2zy2A:
undetectable		 5eezN-2zy2A:
8.61
5eezO-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.28A 5eezP-2zy2A:
undetectable
5eezQ-2zy2A:
undetectable		 5eezP-2zy2A:
8.61
5eezQ-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 5eezQ-2zy2A:
undetectable
5eezR-2zy2A:
undetectable		 5eezQ-2zy2A:
8.61
5eezR-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 5eezR-2zy2A:
undetectable
5eezS-2zy2A:
undetectable		 5eezR-2zy2A:
8.61
5eezS-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.27A 5eezS-2zy2A:
undetectable
5eezT-2zy2A:
undetectable		 5eezS-2zy2A:
8.61
5eezT-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.30A 5eezT-2zy2A:
undetectable
5eezU-2zy2A:
undetectable		 5eezT-2zy2A:
8.61
5eezU-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.27A 5eezU-2zy2A:
undetectable
5eezV-2zy2A:
undetectable		 5eezU-2zy2A:
8.61
5eezV-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.27A 5ef0E-2zy2A:
undetectable
5ef0F-2zy2A:
undetectable		 5ef0E-2zy2A:
8.61
5ef0F-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.25A 5ef0G-2zy2A:
undetectable
5ef0H-2zy2A:
undetectable		 5ef0G-2zy2A:
8.61
5ef0H-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 11 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.26A 5ef0I-2zy2A:
undetectable
5ef0J-2zy2A:
undetectable		 5ef0I-2zy2A:
8.61
5ef0J-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.27A 5ef0J-2zy2A:
undetectable
5ef0K-2zy2A:
undetectable		 5ef0J-2zy2A:
8.61
5ef0K-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 5ef0N-2zy2A:
undetectable
5ef0O-2zy2A:
undetectable		 5ef0N-2zy2A:
8.61
5ef0O-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.28A 5ef0P-2zy2A:
undetectable
5ef0Q-2zy2A:
undetectable		 5ef0P-2zy2A:
8.61
5ef0Q-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 5ef0Q-2zy2A:
undetectable
5ef0R-2zy2A:
undetectable		 5ef0Q-2zy2A:
8.61
5ef0R-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 5ef0R-2zy2A:
undetectable
5ef0S-2zy2A:
undetectable		 5ef0R-2zy2A:
8.61
5ef0S-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.27A 5ef0S-2zy2A:
undetectable
5ef0T-2zy2A:
undetectable		 5ef0S-2zy2A:
8.61
5ef0T-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.30A 5ef0T-2zy2A:
undetectable
5ef0U-2zy2A:
undetectable		 5ef0T-2zy2A:
8.61
5ef0U-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.27A 5ef0U-2zy2A:
undetectable
5ef0V-2zy2A:
undetectable		 5ef0U-2zy2A:
8.61
5ef0V-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.27A 5ef1E-2zy2A:
undetectable
5ef1F-2zy2A:
undetectable		 5ef1E-2zy2A:
8.61
5ef1F-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.25A 5ef1G-2zy2A:
undetectable
5ef1H-2zy2A:
undetectable		 5ef1G-2zy2A:
8.61
5ef1H-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 11 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.26A 5ef1I-2zy2A:
undetectable
5ef1J-2zy2A:
undetectable		 5ef1I-2zy2A:
8.61
5ef1J-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.27A 5ef1J-2zy2A:
undetectable
5ef1K-2zy2A:
undetectable		 5ef1J-2zy2A:
8.61
5ef1K-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 5ef1N-2zy2A:
undetectable
5ef1O-2zy2A:
undetectable		 5ef1N-2zy2A:
8.61
5ef1O-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.28A 5ef1P-2zy2A:
undetectable
5ef1Q-2zy2A:
undetectable		 5ef1P-2zy2A:
8.61
5ef1Q-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 5ef1Q-2zy2A:
undetectable
5ef1R-2zy2A:
undetectable		 5ef1Q-2zy2A:
8.61
5ef1R-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 5ef1R-2zy2A:
undetectable
5ef1S-2zy2A:
undetectable		 5ef1R-2zy2A:
8.61
5ef1S-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.27A 5ef1S-2zy2A:
undetectable
5ef1T-2zy2A:
undetectable		 5ef1S-2zy2A:
8.61
5ef1T-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.30A 5ef1T-2zy2A:
undetectable
5ef1U-2zy2A:
undetectable		 5ef1T-2zy2A:
8.61
5ef1U-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.27A 5ef1U-2zy2A:
undetectable
5ef1V-2zy2A:
undetectable		 5ef1U-2zy2A:
8.61
5ef1V-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.27A 5ef2E-2zy2A:
undetectable
5ef2F-2zy2A:
undetectable		 5ef2E-2zy2A:
8.61
5ef2F-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.25A 5ef2G-2zy2A:
undetectable
5ef2H-2zy2A:
undetectable		 5ef2G-2zy2A:
8.61
5ef2H-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 11 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.26A 5ef2I-2zy2A:
undetectable
5ef2J-2zy2A:
undetectable		 5ef2I-2zy2A:
8.61
5ef2J-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.27A 5ef2J-2zy2A:
undetectable
5ef2K-2zy2A:
undetectable		 5ef2J-2zy2A:
8.61
5ef2K-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 5ef2N-2zy2A:
undetectable
5ef2O-2zy2A:
undetectable		 5ef2N-2zy2A:
8.61
5ef2O-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.28A 5ef2P-2zy2A:
undetectable
5ef2Q-2zy2A:
undetectable		 5ef2P-2zy2A:
8.61
5ef2Q-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 5ef2Q-2zy2A:
undetectable
5ef2R-2zy2A:
undetectable		 5ef2Q-2zy2A:
8.61
5ef2R-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 5ef2R-2zy2A:
undetectable
5ef2S-2zy2A:
undetectable		 5ef2R-2zy2A:
8.61
5ef2S-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.27A 5ef2S-2zy2A:
undetectable
5ef2T-2zy2A:
undetectable		 5ef2S-2zy2A:
8.61
5ef2T-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.30A 5ef2T-2zy2A:
undetectable
5ef2U-2zy2A:
undetectable		 5ef2T-2zy2A:
8.61
5ef2U-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.27A 5ef2U-2zy2A:
undetectable
5ef2V-2zy2A:
undetectable		 5ef2U-2zy2A:
8.61
5ef2V-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.27A 5ef3E-2zy2A:
undetectable
5ef3F-2zy2A:
undetectable		 5ef3E-2zy2A:
8.61
5ef3F-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.25A 5ef3G-2zy2A:
undetectable
5ef3H-2zy2A:
undetectable		 5ef3G-2zy2A:
8.61
5ef3H-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 11 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.26A 5ef3I-2zy2A:
undetectable
5ef3J-2zy2A:
undetectable		 5ef3I-2zy2A:
8.61
5ef3J-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 SER A  62
GLY A 128
HIS A 123
ALA A  58
ILE A 129
 None
 1.26A 5ef3J-2zy2A:
undetectable
5ef3K-2zy2A:
undetectable		 5ef3J-2zy2A:
8.61
5ef3K-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 5ef3N-2zy2A:
undetectable
5ef3O-2zy2A:
undetectable		 5ef3N-2zy2A:
8.61
5ef3O-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.28A 5ef3P-2zy2A:
undetectable
5ef3Q-2zy2A:
undetectable		 5ef3P-2zy2A:
8.61
5ef3Q-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 9 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 5ef3Q-2zy2A:
undetectable
5ef3R-2zy2A:
undetectable		 5ef3Q-2zy2A:
8.61
5ef3R-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.29A 5ef3R-2zy2A:
undetectable
5ef3S-2zy2A:
undetectable		 5ef3R-2zy2A:
8.61
5ef3S-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.27A 5ef3S-2zy2A:
undetectable
5ef3T-2zy2A:
undetectable		 5ef3S-2zy2A:
8.61
5ef3T-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.30A 5ef3T-2zy2A:
undetectable
5ef3U-2zy2A:
undetectable		 5ef3T-2zy2A:
8.61
5ef3U-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 GLY A 128
HIS A 123
ALA A  58
ILE A 129
SER A  62
 None
 1.27A 5ef3U-2zy2A:
undetectable
5ef3V-2zy2A:
undetectable		 5ef3U-2zy2A:
8.61
5ef3V-2zy2A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HKG_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1B)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 12 ASP A 286
PHE A 204
ILE A 210
ILE A 181
PHE A 250
 PLP  A 900 (-3.2A)
PLP  A 900 (-4.2A)
None
None
None
 0.99A 5hkgA-2zy2A:
undetectable		 5hkgA-2zy2A:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		4 / 6 SER A 397
GLY A 325
MET A 393
ILE A 152
 None
 1.07A 5j4nA-2zy2A:
undetectable		 5j4nA-2zy2A:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 12 LEU A 281
ALA A 272
SER A 266
LEU A 267
LEU A 238
 None
 1.21A 5mwyA-2zy2A:
undetectable		 5mwyA-2zy2A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_F_CCSF14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		4 / 6 PHE A 317
LEU A  43
SER A 314
GLY A 321
 None
None
PLP  A 900 ( 3.7A)
None
 1.08A 5o4yF-2zy2A:
undetectable		 5o4yF-2zy2A:
3.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_A_ACTA703_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		4 / 6 ARG A  48
ALA A  50
PRO A  47
PHE A 396
 None
 1.07A 5odqA-2zy2A:
undetectable		 5odqA-2zy2A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		4 / 8 GLU A  61
VAL A 126
GLY A  82
LEU A  80
 None
 1.10A 5syjA-2zy2A:
1.9		 5syjA-2zy2A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		4 / 8 GLY A 318
THR A 320
PHE A 292
TYR A 289
 None
None
None
PLP  A 900 (-4.0A)
 1.03A 6eqpA-2zy2A:
2.4		 6eqpA-2zy2A:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 12 ASP A 286
PHE A 204
ILE A 210
ILE A 181
PHE A 250
 PLP  A 900 (-3.2A)
PLP  A 900 (-4.2A)
None
None
None
 1.06A 6mkeA-2zy2A:
undetectable
6mkeD-2zy2A:
undetectable		 6mkeA-2zy2A:
8.27
6mkeD-2zy2A:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)		 2zy2 L-ASPARTATE
4-CARBOXYLYASE
(Pseudomonas
sp.
ATCC
19121) 		5 / 10 ASP A 286
PHE A 204
ILE A 210
ILE A 181
PHE A 250
 PLP  A 900 (-3.2A)
PLP  A 900 (-4.2A)
None
None
None
 1.15A 6mkeC-2zy2A:
undetectable		 6mkeC-2zy2A:
8.27