SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zyz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
(Pyrobaculum
aerophilum) 		5 / 9 SER A  63
GLY A  59
VAL A  66
GLU A  34
ILE A  56
 None
 1.23A 1pw7B-2zyzA:
undetectable		 1pw7B-2zyzA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_2
(POL POLYPROTEIN)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
TRNA-SPLICING
ENDONUCLEASE
(Pyrobaculum
aerophilum) 		5 / 10 GLY A  44
ASP B 146
ILE B 147
ILE B 142
ALA A  69
 None
 1.07A 1sh9B-2zyzA:
undetectable		 1sh9B-2zyzA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
(Pyrobaculum
aerophilum) 		5 / 11 SER A  63
GLY A  59
VAL A  66
GLU A  34
ILE A  56
 None
 1.18A 1vhwA-2zyzA:
undetectable
1vhwD-2zyzA:
undetectable		 1vhwA-2zyzA:
17.77
1vhwD-2zyzA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
(Pyrobaculum
aerophilum) 		5 / 11 SER A  63
GLY A  59
VAL A  66
GLU A  34
ILE A  56
 None
 1.17A 1vhwC-2zyzA:
undetectable
1vhwE-2zyzA:
undetectable		 1vhwC-2zyzA:
17.77
1vhwE-2zyzA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
(Pyrobaculum
aerophilum) 		5 / 11 SER A  63
GLY A  59
VAL A  66
GLU A  34
ILE A  56
 None
 1.17A 1vhwA-2zyzA:
undetectable
1vhwD-2zyzA:
undetectable		 1vhwA-2zyzA:
17.77
1vhwD-2zyzA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
(Pyrobaculum
aerophilum) 		5 / 11 SER A  63
GLY A  59
VAL A  66
GLU A  34
ILE A  56
 None
 1.19A 1vhwC-2zyzA:
undetectable
1vhwE-2zyzA:
undetectable		 1vhwC-2zyzA:
17.77
1vhwE-2zyzA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VM1_A_TAZA504_1
(BETA-LACTAMASE SHV-1)		 2zyz TRNA-SPLICING
ENDONUCLEASE
(Pyrobaculum
aerophilum) 		3 / 3 ASP B  34
TYR B  33
GLU B  40
 None
 0.74A 1vm1A-2zyzB:
undetectable		 1vm1A-2zyzB:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA502_1
(CYTOCHROME P450 2B4)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
TRNA-SPLICING
ENDONUCLEASE
(Pyrobaculum
aerophilum) 		5 / 12 LEU A  68
ILE B 142
LEU B 163
THR B 162
LEU B 176
 None
 0.83A 2bdmA-2zyzA:
undetectable		 2bdmA-2zyzA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
(Pyrobaculum
aerophilum) 		3 / 3 TYR A  79
VAL A   8
THR A  78
 None
 0.77A 2ygnA-2zyzA:
undetectable		 2ygnA-2zyzA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
TRNA-SPLICING
ENDONUCLEASE
(Pyrobaculum
aerophilum;
Pyrobaculum
aerophilum) 		4 / 4 LEU A  87
PRO A  88
LEU B 103
ARG B 101
 None
 1.25A 3hcoB-2zyzA:
undetectable		 3hcoB-2zyzA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KSZ_A_CYSA620_0
(LACTOPEROXIDASE)		 2zyz TRNA-SPLICING
ENDONUCLEASE
(Pyrobaculum
aerophilum) 		3 / 3 ARG B  88
GLU B 137
PHE B 135
 None
 0.72A 4kszA-2zyzB:
undetectable		 4kszA-2zyzB:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
(Pyrobaculum
aerophilum) 		5 / 9 SER A  63
GLY A  59
VAL A  66
GLU A  34
ILE A  56
 None
 1.21A 5i3cA-2zyzA:
undetectable		 5i3cA-2zyzA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
(Pyrobaculum
aerophilum) 		5 / 11 SER A  63
GLY A  59
VAL A  66
GLU A  34
ILE A  56
 None
 1.24A 5i3cC-2zyzA:
undetectable		 5i3cC-2zyzA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
(Pyrobaculum
aerophilum) 		3 / 3 VAL A  77
VAL A  71
GLN A   5
 None
 0.66A 5qgjA-2zyzA:
undetectable		 5qgjA-2zyzA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
(Pyrobaculum
aerophilum) 		3 / 3 VAL A  77
VAL A  71
GLN A   5
 None
 0.60A 5qgmA-2zyzA:
undetectable		 5qgmA-2zyzA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
(Pyrobaculum
aerophilum) 		3 / 3 VAL A  77
VAL A  71
GLN A   5
 None
 0.69A 5qguA-2zyzA:
undetectable		 5qguA-2zyzA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
(Pyrobaculum
aerophilum) 		3 / 3 VAL A  77
VAL A  71
GLN A   5
 None
 0.69A 5qgvA-2zyzA:
undetectable		 5qgvA-2zyzA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
(Pyrobaculum
aerophilum) 		3 / 3 VAL A  77
VAL A  71
GLN A   5
 None
 0.70A 5qgwA-2zyzA:
undetectable		 5qgwA-2zyzA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
(Pyrobaculum
aerophilum) 		3 / 3 VAL A  77
VAL A  71
GLN A   5
 None
 0.70A 5qgxA-2zyzA:
undetectable		 5qgxA-2zyzA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
(Pyrobaculum
aerophilum) 		3 / 3 VAL A  77
VAL A  71
GLN A   5
 None
 0.69A 5qh1A-2zyzA:
undetectable		 5qh1A-2zyzA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
(Pyrobaculum
aerophilum) 		3 / 3 VAL A  77
VAL A  71
GLN A   5
 None
 0.68A 5qh4A-2zyzA:
undetectable		 5qh4A-2zyzA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
(Pyrobaculum
aerophilum) 		3 / 3 VAL A  77
VAL A  71
GLN A   5
 None
 0.67A 5qh5A-2zyzA:
undetectable		 5qh5A-2zyzA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
(Pyrobaculum
aerophilum) 		3 / 3 VAL A  77
VAL A  71
GLN A   5
 None
 0.67A 5qh6A-2zyzA:
undetectable		 5qh6A-2zyzA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
(Pyrobaculum
aerophilum) 		3 / 3 VAL A  77
VAL A  71
GLN A   5
 None
 0.67A 5qh9A-2zyzA:
undetectable		 5qh9A-2zyzA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
(Pyrobaculum
aerophilum) 		3 / 3 VAL A  77
VAL A  71
GLN A   5
 None
 0.66A 5qhcA-2zyzA:
undetectable		 5qhcA-2zyzA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
(Pyrobaculum
aerophilum) 		3 / 3 VAL A  77
VAL A  71
GLN A   5
 None
 0.67A 5qheA-2zyzA:
undetectable		 5qheA-2zyzA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
(Pyrobaculum
aerophilum) 		3 / 3 VAL A  77
VAL A  71
GLN A   5
 None
 0.68A 5qhfA-2zyzA:
undetectable		 5qhfA-2zyzA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
(Pyrobaculum
aerophilum) 		3 / 3 VAL A  77
VAL A  71
GLN A   5
 None
 0.66A 5qhgA-2zyzA:
undetectable		 5qhgA-2zyzA:
19.31