SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2zzt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W67_A_VIVA301_0 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	2zzt	PUTATIVE UNCHARACTERIZED PROTEIN (Thermotoga maritima)	5 / 11	ILE A 238 ILE A 220 VAL A 223 LEU A 224 VAL A 230	None	0.78A	3w67A-2zztA: undetectable	3w67A-2zztA: 15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QT2_A_RAPA202_1 (FK506-BINDING PROTEIN (FKBP)-TYPE PEPTIDYL-PROPYL ISOMERASE)	2zzt	PUTATIVE UNCHARACTERIZED PROTEIN (Thermotoga maritima)	5 / 10	ASP A 279 GLU A 272 VAL A 223 ILE A 220 ILE A 238	None	1.41A	4qt2A-2zztA: undetectable	4qt2A-2zztA: 24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QT3_A_RAPA202_1 (FK506-BINDING PROTEIN (FKBP)-TYPE PEPTIDYL-PROPYL ISOMERASE)	2zzt	PUTATIVE UNCHARACTERIZED PROTEIN (Thermotoga maritima)	5 / 10	ASP A 279 GLU A 272 VAL A 223 ILE A 220 ILE A 238	None	1.36A	4qt3A-2zztA: undetectable	4qt3A-2zztA: 23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MUE_A_VIVA302_0 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	2zzt	PUTATIVE UNCHARACTERIZED PROTEIN (Thermotoga maritima)	5 / 12	ILE A 220 VAL A 223 LEU A 224 VAL A 230 ILE A 251	None	0.98A	5mueA-2zztA: undetectable	5mueA-2zztA: 18.86

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3W67_A_VIVA301_0","ALPHA-TOCOPHEROL TRANSFER PROTEIN","2zzt","PUTATIVE UNCHARACTERIZED PROTEIN","Thermotoga maritima",5,"ILE A 238;ILE A 220;VAL A 223;LEU A 224;VAL A 230","None","0.78A","3w67A-2zztA:undetectable","3w67A-2zztA:15.79"],["4QT2_A_RAPA202_1","FK506-BINDING PROTEIN (FKBP)-TYPE PEPTIDYL-PROPYL ISOMERASE","2zzt","PUTATIVE UNCHARACTERIZED PROTEIN","Thermotoga maritima",5,"ASP A 279;GLU A 272;VAL A 223;ILE A 220;ILE A 238","None","1.41A","4qt2A-2zztA:undetectable","4qt2A-2zztA:24.44"],["4QT3_A_RAPA202_1","FK506-BINDING PROTEIN (FKBP)-TYPE PEPTIDYL-PROPYL ISOMERASE","2zzt","PUTATIVE UNCHARACTERIZED PROTEIN","Thermotoga maritima",5,"ASP A 279;GLU A 272;VAL A 223;ILE A 220;ILE A 238","None","1.36A","4qt3A-2zztA:undetectable","4qt3A-2zztA:23.91"],["5MUE_A_VIVA302_0","ALPHA-TOCOPHEROL TRANSFER PROTEIN","2zzt","PUTATIVE UNCHARACTERIZED PROTEIN","Thermotoga maritima",5,"ILE A 220;VAL A 223;LEU A 224;VAL A 230;ILE A 251","None","0.98A","5mueA-2zztA:undetectable","5mueA-2zztA:18.86"]]