SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a01'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 3a01 HOMEOBOX PROTEIN
ARISTALESS
(Drosophila
melanogaster) 		3 / 3 THR B 107
ASP B 111
GLU B 117
 None
 0.75A 3qowA-3a01B:
undetectable		 3qowA-3a01B:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 3a01 HOMEODOMAIN-CONTAINI
NG PROTEIN
(Drosophila
melanogaster) 		3 / 3 LYS A 186
LYS A 187
PRO A 188
 None
 1.28A 4dv1L-3a01A:
undetectable		 4dv1L-3a01A:
25.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)		 3a01 HOMEODOMAIN-CONTAINI
NG PROTEIN
(Drosophila
melanogaster) 		3 / 3 TRP A 232
ARG A 236
LEU A 210
 None
 0.70A 5dbyA-3a01A:
undetectable		 5dbyA-3a01A:
9.06