SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a0g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_A_ESTA351_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3a0g HEMOGLOBIN SUBUNIT
ALPHA
(Cavia
porcellus) 		5 / 12 VAL A  25
GLY A  28
LEU A 101
GLY A  59
LEU A 136
 None
None
HEM  A 201 (-4.1A)
None
None
 1.06A 1fduA-3a0gA:
undetectable		 1fduA-3a0gA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1501_0
(FERROCHELATASE)		 3a0g HEMOGLOBIN SUBUNIT
ALPHA
(Cavia
porcellus) 		5 / 12 LEU A  29
PHE A  33
LEU A 101
ILE A  46
LEU A 136
 None
None
HEM  A 201 (-4.1A)
None
None
 1.14A 1hrkA-3a0gA:
undetectable		 1hrkA-3a0gA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2501_0
(FERROCHELATASE)		 3a0g HEMOGLOBIN SUBUNIT
ALPHA
(Cavia
porcellus) 		5 / 12 LEU A  29
PHE A  33
LEU A 101
ILE A  46
HIS A  87
 None
None
HEM  A 201 (-4.1A)
None
HEM  A 201 (-3.3A)
 1.31A 1hrkB-3a0gA:
undetectable		 1hrkB-3a0gA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)		 3a0g HEMOGLOBIN SUBUNIT
ALPHA
(Cavia
porcellus) 		5 / 11 VAL A  25
GLY A  28
LEU A 101
GLY A  59
HIS A  87
 None
None
HEM  A 201 (-4.1A)
None
HEM  A 201 (-3.3A)
 1.11A 1iolA-3a0gA:
undetectable		 1iolA-3a0gA:
18.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IWH_A_PEMA501_1
(HEMOGLOBIN ALPHA
CHAIN)		 3a0g HEMOGLOBIN SUBUNIT
ALPHA
(Cavia
porcellus) 		6 / 6 ALA A  57
LYS A  60
LYS A  61
ASP A  64
ALA A  65
LEU A  83
 None
None
HEM  A 201 (-4.5A)
None
HEM  A 201 ( 3.8A)
HEM  A 201 ( 4.6A)
 0.53A 1iwhA-3a0gA:
26.0		 1iwhA-3a0gA:
76.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3a0g HEMOGLOBIN SUBUNIT
BETA
(Cavia
porcellus) 		4 / 7 PHE B  42
PHE B  45
VAL B  67
HIS B  92
 HEM  B 401 (-4.4A)
None
HEM  B 401 (-3.9A)
HEM  B 401 (-3.2A)
 0.79A 1lh6A-3a0gB:
13.2		 1lh6A-3a0gB:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3a0g HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA
(Cavia
porcellus) 		5 / 12 PHE B  71
PHE B 130
PHE A  36
PHE B 122
ALA B  27
 None
 1.19A 1q23A-3a0gB:
undetectable
1q23B-3a0gB:
undetectable		 1q23A-3a0gB:
22.11
1q23B-3a0gB:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3a0g HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA
(Cavia
porcellus) 		5 / 12 PHE B 130
VAL A 107
PHE B 122
ALA B  27
ALA B 113
 None
 1.27A 1q23A-3a0gB:
undetectable
1q23B-3a0gB:
undetectable		 1q23A-3a0gB:
22.11
1q23B-3a0gB:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TBF_A_VIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3a0g HEMOGLOBIN SUBUNIT
BETA
(Cavia
porcellus) 		5 / 9 LEU B  68
LEU B 110
VAL B 137
ALA B 140
LEU B  88
 None
None
None
None
HEM  B 401 ( 4.7A)
 1.27A 1tbfA-3a0gB:
undetectable		 1tbfA-3a0gB:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_A_MTXA605_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 3a0g HEMOGLOBIN SUBUNIT
BETA
(Cavia
porcellus) 		5 / 12 VAL B 137
LEU B  68
PHE B  71
SER B  72
ILE B 114
 None
 0.83A 2oipA-3a0gB:
undetectable		 2oipA-3a0gB:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3a0g HEMOGLOBIN SUBUNIT
ALPHA
(Cavia
porcellus) 		5 / 12 LEU A  29
PHE A  33
LEU A 101
ILE A  46
HIS A  87
 None
None
HEM  A 201 (-4.1A)
None
HEM  A 201 (-3.3A)
 1.19A 2pnjB-3a0gA:
undetectable		 2pnjB-3a0gA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3a0g HEMOGLOBIN SUBUNIT
ALPHA
(Cavia
porcellus) 		5 / 12 LEU A  29
PHE A  33
LEU A 101
ILE A  46
LEU A 136
 None
None
HEM  A 201 (-4.1A)
None
None
 1.09A 2po5A-3a0gA:
undetectable		 2po5A-3a0gA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3a0g HEMOGLOBIN SUBUNIT
ALPHA
(Cavia
porcellus) 		5 / 12 LEU A  29
PHE A  33
LEU A 101
ILE A  46
HIS A  87
 None
None
HEM  A 201 (-4.1A)
None
HEM  A 201 (-3.3A)
 1.19A 2po7A-3a0gA:
undetectable		 2po7A-3a0gA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3a0g HEMOGLOBIN SUBUNIT
ALPHA
(Cavia
porcellus) 		5 / 12 LEU A  29
PHE A  33
LEU A 101
ILE A  46
LEU A 136
 None
None
HEM  A 201 (-4.1A)
None
None
 1.09A 2po7A-3a0gA:
undetectable		 2po7A-3a0gA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3a0g HEMOGLOBIN SUBUNIT
ALPHA
(Cavia
porcellus) 		5 / 12 LEU A  29
PHE A  33
LEU A 101
ILE A  46
LEU A 136
 None
None
HEM  A 201 (-4.1A)
None
None
 1.19A 2po7B-3a0gA:
undetectable		 2po7B-3a0gA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_D_D16D609_1
(THYMIDYLATE SYNTHASE)		 3a0g HEMOGLOBIN SUBUNIT
BETA
(Cavia
porcellus) 		5 / 9 ASP B  47
LEU B  48
GLY B  46
PHE B  45
THR B  38
 None
None
None
None
HEM  B 401 ( 4.4A)
 1.34A 2tsrD-3a0gB:
undetectable		 2tsrD-3a0gB:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB6_0
(FERROCHELATASE)		 3a0g HEMOGLOBIN SUBUNIT
ALPHA
(Cavia
porcellus) 		5 / 12 LEU A  29
PHE A  33
LEU A 101
ILE A  46
HIS A  87
 None
None
HEM  A 201 (-4.1A)
None
HEM  A 201 (-3.3A)
 1.23A 3aqiB-3a0gA:
undetectable		 3aqiB-3a0gA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_D_MTXD615_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 3a0g HEMOGLOBIN SUBUNIT
BETA
(Cavia
porcellus) 		5 / 12 VAL B 137
LEU B  68
PHE B  71
SER B  72
ILE B 114
 None
 0.68A 3hj3D-3a0gB:
undetectable		 3hj3D-3a0gB:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA202_1
(PROTEIN S100-A4)		 3a0g HEMOGLOBIN SUBUNIT
BETA
(Cavia
porcellus) 		5 / 12 LEU B  68
SER B  70
PHE B  71
LEU B 106
PHE B  85
 None
HEM  B 401 ( 3.8A)
None
HEM  B 401 ( 4.5A)
None
 1.16A 3ko0A-3a0gB:
undetectable
3ko0B-3a0gB:
undetectable
3ko0C-3a0gB:
undetectable
3ko0D-3a0gB:
undetectable		 3ko0A-3a0gB:
21.92
3ko0B-3a0gB:
21.92
3ko0C-3a0gB:
21.92
3ko0D-3a0gB:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)		 3a0g HEMOGLOBIN SUBUNIT
BETA
(Cavia
porcellus) 		5 / 12 PHE B  85
LEU B  68
SER B  70
PHE B  71
LEU B 106
 None
None
HEM  B 401 ( 3.8A)
None
HEM  B 401 ( 4.5A)
 1.14A 3ko0G-3a0gB:
undetectable
3ko0H-3a0gB:
undetectable
3ko0I-3a0gB:
undetectable
3ko0J-3a0gB:
undetectable		 3ko0G-3a0gB:
21.92
3ko0H-3a0gB:
21.92
3ko0I-3a0gB:
21.92
3ko0J-3a0gB:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ202_1
(PROTEIN S100-A4)		 3a0g HEMOGLOBIN SUBUNIT
BETA
(Cavia
porcellus) 		5 / 11 PHE B  85
LEU B 106
LEU B  68
SER B  70
PHE B  71
 None
HEM  B 401 ( 4.5A)
None
HEM  B 401 ( 3.8A)
None
 1.18A 3ko0A-3a0gB:
undetectable
3ko0B-3a0gB:
undetectable
3ko0I-3a0gB:
undetectable
3ko0J-3a0gB:
undetectable		 3ko0A-3a0gB:
21.92
3ko0B-3a0gB:
21.92
3ko0I-3a0gB:
21.92
3ko0J-3a0gB:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK202_1
(PROTEIN S100-A4)		 3a0g HEMOGLOBIN SUBUNIT
BETA
(Cavia
porcellus) 		5 / 12 LEU B  68
SER B  70
PHE B  71
LEU B 106
PHE B  85
 None
HEM  B 401 ( 3.8A)
None
HEM  B 401 ( 4.5A)
None
 1.20A 3ko0K-3a0gB:
undetectable
3ko0L-3a0gB:
undetectable
3ko0S-3a0gB:
undetectable
3ko0T-3a0gB:
undetectable		 3ko0K-3a0gB:
21.92
3ko0L-3a0gB:
21.92
3ko0S-3a0gB:
21.92
3ko0T-3a0gB:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL202_1
(PROTEIN S100-A4)		 3a0g HEMOGLOBIN SUBUNIT
BETA
(Cavia
porcellus) 		5 / 12 LEU B 106
LEU B  68
SER B  70
PHE B  71
PHE B  85
 HEM  B 401 ( 4.5A)
None
HEM  B 401 ( 3.8A)
None
None
 1.15A 3ko0K-3a0gB:
undetectable
3ko0L-3a0gB:
undetectable
3ko0M-3a0gB:
undetectable
3ko0N-3a0gB:
undetectable		 3ko0K-3a0gB:
21.92
3ko0L-3a0gB:
21.92
3ko0M-3a0gB:
21.92
3ko0N-3a0gB:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)		 3a0g HEMOGLOBIN SUBUNIT
BETA
(Cavia
porcellus) 		5 / 12 LEU B  68
SER B  70
PHE B  71
LEU B 106
PHE B  85
 None
HEM  B 401 ( 3.8A)
None
HEM  B 401 ( 4.5A)
None
 1.19A 3ko0M-3a0gB:
undetectable
3ko0N-3a0gB:
undetectable
3ko0O-3a0gB:
undetectable
3ko0P-3a0gB:
undetectable		 3ko0M-3a0gB:
21.92
3ko0N-3a0gB:
21.92
3ko0O-3a0gB:
21.92
3ko0P-3a0gB:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 3a0g HEMOGLOBIN SUBUNIT
BETA
(Cavia
porcellus) 		5 / 12 PHE B  85
LEU B 106
LEU B  68
SER B  70
PHE B  71
 None
HEM  B 401 ( 4.5A)
None
HEM  B 401 ( 3.8A)
None
 1.22A 3ko0M-3a0gB:
undetectable
3ko0N-3a0gB:
undetectable
3ko0O-3a0gB:
undetectable
3ko0P-3a0gB:
undetectable		 3ko0M-3a0gB:
21.92
3ko0N-3a0gB:
21.92
3ko0O-3a0gB:
21.92
3ko0P-3a0gB:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3a0g HEMOGLOBIN SUBUNIT
BETA
(Cavia
porcellus) 		5 / 12 ALA B  27
GLY B  29
GLY B  64
LEU B  68
HIS B 117
 None
 1.10A 3ou6B-3a0gB:
undetectable		 3ou6B-3a0gB:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3a0g HEMOGLOBIN SUBUNIT
BETA
(Cavia
porcellus) 		5 / 12 ALA B  27
GLY B  29
GLY B  64
LEU B  68
HIS B 117
 None
 1.10A 3ou7B-3a0gB:
undetectable		 3ou7B-3a0gB:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3a0g HEMOGLOBIN SUBUNIT
ALPHA
(Cavia
porcellus) 		5 / 12 LEU A  29
PHE A  33
LEU A 101
ILE A  46
HIS A  87
 None
None
HEM  A 201 (-4.1A)
None
HEM  A 201 (-3.3A)
 1.21A 3w1wA-3a0gA:
undetectable		 3w1wA-3a0gA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3a0g HEMOGLOBIN SUBUNIT
ALPHA
(Cavia
porcellus) 		5 / 12 LEU A  29
PHE A  33
LEU A 101
ILE A  46
HIS A  87
 None
None
HEM  A 201 (-4.1A)
None
HEM  A 201 (-3.3A)
 1.26A 3w1wB-3a0gA:
undetectable		 3w1wB-3a0gA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3a0g HEMOGLOBIN SUBUNIT
ALPHA
(Cavia
porcellus) 		5 / 12 LEU A  29
VAL A  25
LEU A 105
LEU A  66
THR A  67
 None
None
None
HEM  A 201 ( 4.4A)
None
 0.98A 4m2wA-3a0gA:
undetectable		 4m2wA-3a0gA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 3a0g HEMOGLOBIN SUBUNIT
BETA
(Cavia
porcellus) 		3 / 3 PHE B  85
THR B 111
LEU B  75
 None
 0.59A 4qztA-3a0gB:
undetectable		 4qztA-3a0gB:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 3a0g HEMOGLOBIN SUBUNIT
BETA
(Cavia
porcellus) 		4 / 6 ASP B  47
LEU B  48
GLY B  46
PHE B  45
 None
 1.06A 5nooC-3a0gB:
undetectable		 5nooC-3a0gB:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 3a0g HEMOGLOBIN SUBUNIT
BETA
(Cavia
porcellus) 		5 / 8 ARG B  40
ASP B  47
LEU B  48
GLY B  46
PHE B  45
 None
 1.48A 5nooD-3a0gB:
undetectable		 5nooD-3a0gB:
20.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X2S_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 3a0g HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA
(Cavia
porcellus) 		4 / 8 PRO A  95
THR A 134
THR A 137
TRP B  37
 None
 0.63A 5x2sI-3a0gA:
24.8
5x2sJ-3a0gA:
20.8
5x2sK-3a0gA:
25.1		 5x2sI-3a0gA:
75.89
5x2sJ-3a0gA:
38.00
5x2sK-3a0gA:
75.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 3a0g HEMOGLOBIN SUBUNIT
ALPHA
(Cavia
porcellus) 		4 / 8 PRO A  95
ALA A 130
THR A 134
THR A 137
 None
 0.49A 5x2tI-3a0gA:
25.1
5x2tJ-3a0gA:
20.9
5x2tK-3a0gA:
25.1
5x2tL-3a0gA:
19.6		 5x2tI-3a0gA:
75.89
5x2tJ-3a0gA:
38.00
5x2tK-3a0gA:
75.89
5x2tL-3a0gA:
38.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 3a0g HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA
(Cavia
porcellus) 		4 / 8 PRO A  95
ALA A 130
THR A 134
TRP B  37
 None
 0.81A 5x2tI-3a0gA:
25.1
5x2tJ-3a0gA:
20.9
5x2tK-3a0gA:
25.1
5x2tL-3a0gA:
19.6		 5x2tI-3a0gA:
75.89
5x2tJ-3a0gA:
38.00
5x2tK-3a0gA:
75.89
5x2tL-3a0gA:
38.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BTX_A_EDTA503_0
(SOLUTE CARRIER
FAMILY 39
(IRON-REGULATED
TRANSPORTER))		 3a0g HEMOGLOBIN SUBUNIT
BETA
(Cavia
porcellus) 		4 / 7 SER B  70
HIS B  63
GLY B  64
LEU B  88
 HEM  B 401 ( 3.8A)
OXY  B 501 ( 4.1A)
None
HEM  B 401 ( 4.7A)
 1.12A 6btxA-3a0gB:
undetectable		 6btxA-3a0gB:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3a0g HEMOGLOBIN SUBUNIT
ALPHA
(Cavia
porcellus) 		5 / 9 LEU A  66
THR A  67
GLY A  18
ILE A  17
PHE A 128
 HEM  A 201 ( 4.4A)
None
None
None
None
 1.29A 6ebpA-3a0gA:
undetectable		 6ebpA-3a0gA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_C_PCFC607_0
(CYTOCHROME B)		 3a0g HEMOGLOBIN SUBUNIT
ALPHA
(Cavia
porcellus) 		5 / 10 ALA A  69
THR A  13
PHE A 128
PHE A 129
VAL A 132
 None
 1.11A 6hu9C-3a0gA:
undetectable		 6hu9C-3a0gA:
17.45