SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a0r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 3a0r SENSOR PROTEIN
(Thermotoga
maritima) 		4 / 6 LEU A 614
VAL A 618
VAL A 654
GLN A 653
 None
 0.87A 1e7aB-3a0rA:
undetectable		 1e7aB-3a0rA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 3a0r SENSOR PROTEIN
(Thermotoga
maritima) 		4 / 8 PHE A 635
PHE A 633
LEU A 655
VAL A 685
 None
 0.88A 1fslB-3a0rA:
1.5		 1fslB-3a0rA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_2
(CYTOCHROME P450 2C8)		 3a0r SENSOR PROTEIN
(Thermotoga
maritima) 		4 / 8 ILE A 428
ILE A 496
ARG A 458
ALA A 472
 None
 0.70A 2nniA-3a0rA:
undetectable		 2nniA-3a0rA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 3a0r SENSOR PROTEIN
(Thermotoga
maritima) 		3 / 3 THR A 637
SER A 676
PHE A 633
 None
 0.81A 3d4sA-3a0rA:
undetectable		 3d4sA-3a0rA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 3a0r SENSOR PROTEIN
(Thermotoga
maritima) 		5 / 12 THR A 581
ILE A 553
GLY A 557
ASN A 582
LEU A 587
 None
 1.12A 3eeyH-3a0rA:
undetectable		 3eeyH-3a0rA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 3a0r SENSOR PROTEIN
(Thermotoga
maritima) 		5 / 10 ALA A 665
VAL A 742
ILE A 702
ILE A 694
THR A 666
 None
 1.09A 3jw3A-3a0rA:
undetectable		 3jw3A-3a0rA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 3a0r SENSOR PROTEIN
(Thermotoga
maritima) 		5 / 10 GLY A 469
PHE A 465
GLU A 467
LEU A 430
ILE A 428
 None
 1.09A 3kvrA-3a0rA:
undetectable		 3kvrA-3a0rA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 3a0r SENSOR PROTEIN
(Thermotoga
maritima) 		5 / 10 GLY A 469
PHE A 465
GLU A 467
LEU A 430
ILE A 514
 None
 1.34A 3kvrA-3a0rA:
undetectable		 3kvrA-3a0rA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 3a0r SENSOR PROTEIN
(Thermotoga
maritima) 		5 / 10 GLY A 469
PHE A 465
GLU A 467
LEU A 430
ILE A 428
 None
 1.09A 3kvrB-3a0rA:
undetectable		 3kvrB-3a0rA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMA_D_ADND604_1
(PYRUVATE KINASE)		 3a0r SENSOR PROTEIN
(Thermotoga
maritima) 		3 / 3 ARG A 738
GLU A 736
ASN A 737
 None
 0.87A 4imaD-3a0rA:
undetectable		 4imaD-3a0rA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IP7_D_ADND604_1
(PYRUVATE KINASE
ISOZYMES L)		 3a0r SENSOR PROTEIN
(Thermotoga
maritima) 		3 / 3 ARG A 738
GLU A 736
ASN A 737
 None
 0.88A 4ip7D-3a0rA:
undetectable		 4ip7D-3a0rA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ1_B_NPSB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3a0r SENSOR PROTEIN
(Thermotoga
maritima) 		4 / 8 VAL A 475
VAL A 512
ILE A 514
LEU A 484
 None
 0.83A 4jq1B-3a0rA:
undetectable		 4jq1B-3a0rA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3a0r SENSOR PROTEIN
(Thermotoga
maritima) 		4 / 8 THR A 735
ILE A 725
LEU A 716
PHE A 746
 None
 0.76A 4r38A-3a0rA:
9.2		 4r38A-3a0rA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3a0r SENSOR PROTEIN
(Thermotoga
maritima) 		3 / 3 ARG A 497
ILE A 514
PHE A 498
 None
 0.56A 5kirA-3a0rA:
0.2		 5kirA-3a0rA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 3a0r SENSOR PROTEIN
(Thermotoga
maritima) 		4 / 5 LEU A 655
VAL A 618
GLU A 617
LEU A 614
 None
 0.88A 5xooB-3a0rA:
undetectable		 5xooB-3a0rA:
13.06