SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a0v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3a0v SENSOR PROTEIN
(Thermotoga
maritima) 		5 / 12 GLY A 469
SER A 474
ILE A 514
ARG A 435
LEU A 430
 None
None
None
None
EOH  A 101 ( 4.4A)
 1.37A 3iv6C-3a0vA:
undetectable		 3iv6C-3a0vA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ1_B_NPSB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3a0v SENSOR PROTEIN
(Thermotoga
maritima) 		4 / 8 VAL A 475
VAL A 512
ILE A 514
LEU A 484
 None
EOH  A 101 ( 4.7A)
None
None
 0.92A 4jq1B-3a0vA:
undetectable		 4jq1B-3a0vA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3a0v SENSOR PROTEIN
(Thermotoga
maritima) 		3 / 3 ARG A 497
ILE A 514
PHE A 498
 None
 0.51A 5kirA-3a0vA:
undetectable		 5kirA-3a0vA:
11.03