SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a1f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_A_SAMA300_0
(HEMK PROTEIN)		 3a1f CYTOCHROME B-245
HEAVY CHAIN
(Homo
sapiens) 		5 / 12 THR A  97
ILE A  27
GLY A  28
GLY A  24
THR A  30
 None
 0.93A 1nv8A-3a1fA:
3.2		 1nv8A-3a1fA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_B_SAMB301_0
(HEMK PROTEIN)		 3a1f CYTOCHROME B-245
HEAVY CHAIN
(Homo
sapiens) 		5 / 12 THR A  97
ILE A  27
GLY A  28
GLY A  24
THR A  30
 None
 0.90A 1nv8B-3a1fA:
4.3		 1nv8B-3a1fA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_C_H4BC1290_1
(PTERIDINE REDUCTASE
1)		 3a1f CYTOCHROME B-245
HEAVY CHAIN
(Homo
sapiens) 		4 / 8 SER A 168
PHE A 136
LEU A 158
LEU A 152
 None
 0.99A 2bfpC-3a1fA:
3.2		 2bfpC-3a1fA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 3a1f CYTOCHROME B-245
HEAVY CHAIN
(Homo
sapiens) 		4 / 8 SER A 168
PHE A 136
LEU A 158
LEU A 152
 None
 0.98A 2bfpD-3a1fA:
3.1		 2bfpD-3a1fA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 3a1f CYTOCHROME B-245
HEAVY CHAIN
(Homo
sapiens) 		4 / 8 ILE A   1
SER A  11
GLY A   8
SER A  38
 NI  A 193 (-4.0A)
None
None
None
 0.83A 3lslA-3a1fA:
undetectable
3lslD-3a1fA:
undetectable		 3lslA-3a1fA:
20.46
3lslD-3a1fA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 3a1f CYTOCHROME B-245
HEAVY CHAIN
(Homo
sapiens) 		4 / 8 SER A  38
ILE A   1
SER A  11
GLY A   8
 None
NI  A 193 (-4.0A)
None
None
 0.85A 3lslA-3a1fA:
undetectable
3lslD-3a1fA:
undetectable		 3lslA-3a1fA:
20.46
3lslD-3a1fA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U88_A_CHDA611_0
(MENIN)		 3a1f CYTOCHROME B-245
HEAVY CHAIN
(Homo
sapiens) 		3 / 3 SER A 170
PHE A 136
LYS A 137
 None
 0.99A 3u88A-3a1fA:
undetectable		 3u88A-3a1fA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA502_1
(CHITINASE)		 3a1f CYTOCHROME B-245
HEAVY CHAIN
(Homo
sapiens) 		4 / 4 TRP A 132
GLY A  24
TRP A  59
ALA A  25
 None
 1.32A 3wqvA-3a1fA:
undetectable		 3wqvA-3a1fA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA502_1
(CHITINASE)		 3a1f CYTOCHROME B-245
HEAVY CHAIN
(Homo
sapiens) 		4 / 5 TRP A 132
GLY A  24
TRP A  59
ALA A  25
 None
 1.31A 3wqwA-3a1fA:
undetectable		 3wqwA-3a1fA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_A_QI9A602_0
(CYTOCHROME P450 2D6)		 3a1f CYTOCHROME B-245
HEAVY CHAIN
(Homo
sapiens) 		5 / 9 PHE A 136
SER A 163
VAL A  23
PHE A 151
LEU A 152
 None
 1.49A 4wnvA-3a1fA:
undetectable		 4wnvA-3a1fA:
19.58