SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a1i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_0
(FTSJ)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		5 / 12 ALA A 139
GLY A 190
GLY A 173
GLY A 174
ARG A 256
 None
 0.99A 1eizA-3a1iA:
undetectable		 1eizA-3a1iA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_0
(FTSJ)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		5 / 12 ALA A 139
GLY A 190
GLY A 173
GLY A 174
ARG A 256
 None
 0.98A 1ej0A-3a1iA:
undetectable		 1ej0A-3a1iA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_A_CCSA47_0
(GLUTATHIONE
S-TRANSFERASE)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 7 LEU A 277
THR A 489
LEU A 491
GLY A 494
 None
 0.87A 1gtiA-3a1iA:
undetectable		 1gtiA-3a1iA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 7 THR A 424
VAL A 205
GLY A 207
ILE A 233
 None
 0.59A 1gtnC-3a1iA:
undetectable
1gtnD-3a1iA:
undetectable		 1gtnC-3a1iA:
10.57
1gtnD-3a1iA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 8 ARG A 127
PRO A 118
VAL A  99
GLY A 219
 None
 1.02A 1hrkB-3a1iA:
undetectable		 1hrkB-3a1iA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_1
(POL POLYPROTEIN)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		5 / 10 VAL A 124
ILE A 188
GLY A 189
GLY A 190
THR A 218
 None
 0.98A 1k6cA-3a1iA:
undetectable		 1k6cA-3a1iA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 7 GLY A 137
MET A 106
ILE A  80
VAL A 135
 None
 1.03A 1rxcD-3a1iA:
undetectable		 1rxcD-3a1iA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 7 GLY A 137
MET A 106
ILE A  80
VAL A 135
 None
 1.02A 1rxcL-3a1iA:
undetectable		 1rxcL-3a1iA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_2
(POL POLYPROTEIN)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		6 / 10 ARG A 235
GLY A 173
ASP A  97
ILE A  95
GLY A 190
ILE A 196
 None
 1.27A 1sh9B-3a1iA:
undetectable		 1sh9B-3a1iA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FJ1_A_CTCA222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		5 / 12 SER A 147
ARG A 366
THR A 376
VAL A 377
ILE A 223
 None
 1.25A 2fj1A-3a1iA:
undetectable		 2fj1A-3a1iA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JST_A_HLTA101_1
(FOUR-ALPHA-HELIX
BUNDLE)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 5 ALA A  94
TRP A  74
LEU A  71
ALA A 139
 None
 1.05A 2jstA-3a1iA:
undetectable
2jstB-3a1iA:
undetectable		 2jstA-3a1iA:
7.68
2jstB-3a1iA:
7.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O7O_A_DXTA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		5 / 12 SER A 147
ARG A 366
THR A 376
VAL A 377
ILE A 223
 None
 1.48A 2o7oA-3a1iA:
1.1		 2o7oA-3a1iA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 7 ILE A 196
ARG A 197
PRO A 153
GLY A 148
 None
None
None
UNU  A 522 (-3.8A)
 1.03A 2pnjB-3a1iA:
undetectable		 2pnjB-3a1iA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TCT_A_CTCA222_0
(TETRACYCLINE
REPRESSOR)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		5 / 12 SER A 147
ARG A 366
THR A 376
VAL A 377
ILE A 223
 None
 1.24A 2tctA-3a1iA:
undetectable		 2tctA-3a1iA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		5 / 12 VAL A 184
ASN A 160
VAL A 158
GLY A 173
ALA A  73
 None
 1.23A 2x2iA-3a1iA:
undetectable		 2x2iA-3a1iA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_B_J01B600_1
(ORF12)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		5 / 11 ALA A 200
THR A 424
SER A 465
GLY A 204
PHE A 504
 None
 1.07A 2xfsB-3a1iA:
0.8		 2xfsB-3a1iA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		5 / 12 ILE A 196
ALA A 220
GLY A 231
LEU A 358
PRO A 222
 None
 0.98A 2y7hB-3a1iA:
undetectable		 2y7hB-3a1iA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		5 / 12 ILE A 196
ALA A 220
GLY A 231
LEU A 358
PRO A 222
 None
 0.98A 2y7hC-3a1iA:
undetectable		 2y7hC-3a1iA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 8 THR A 236
ARG A 501
ASP A 271
LEU A 270
 None
 0.96A 2zw9A-3a1iA:
undetectable		 2zw9A-3a1iA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_3
(PHOSPHOLIPASE A2)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 5 VAL A 125
VAL A 124
THR A  83
THR A 100
 None
 1.27A 3bjwG-3a1iA:
undetectable		 3bjwG-3a1iA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 5 VAL A 125
VAL A 124
THR A  83
THR A 100
 None
 1.23A 3bjwC-3a1iA:
undetectable		 3bjwC-3a1iA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 5 VAL A 125
VAL A 124
THR A  83
THR A 100
 None
 1.26A 3bjwD-3a1iA:
undetectable		 3bjwD-3a1iA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA201_1
(PROTEIN S100-A4)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		5 / 9 GLY A 482
ILE A 318
PHE A 325
PHE A 456
GLY A 460
 None
 1.23A 3ko0A-3a1iA:
undetectable
3ko0C-3a1iA:
undetectable		 3ko0A-3a1iA:
10.17
3ko0C-3a1iA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI201_1
(PROTEIN S100-A4)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		5 / 9 PHE A 456
GLY A 460
GLY A 482
ILE A 318
PHE A 325
 None
 1.24A 3ko0H-3a1iA:
undetectable
3ko0I-3a1iA:
undetectable		 3ko0H-3a1iA:
10.17
3ko0I-3a1iA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR201_1
(PROTEIN S100-A4)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		5 / 10 GLY A 482
ILE A 318
PHE A 325
PHE A 456
GLY A 460
 None
 1.31A 3ko0R-3a1iA:
undetectable
3ko0T-3a1iA:
undetectable		 3ko0R-3a1iA:
10.17
3ko0T-3a1iA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 6 GLY A 137
MET A 106
ILE A  80
VAL A 135
 None
 1.04A 3kvvA-3a1iA:
undetectable		 3kvvA-3a1iA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 6 GLY A 137
MET A 106
ILE A  80
VAL A 135
 None
 1.06A 3kvvC-3a1iA:
undetectable		 3kvvC-3a1iA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 6 GLY A 137
MET A 106
ILE A  80
VAL A 135
 None
 1.05A 3kvvD-3a1iA:
undetectable		 3kvvD-3a1iA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 6 GLY A 137
MET A 106
ILE A  80
VAL A 135
 None
 1.08A 3kvvE-3a1iA:
undetectable		 3kvvE-3a1iA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 7 VAL A  99
LEU A 128
MET A 243
ILE A 247
 None
 0.99A 3rfmA-3a1iA:
undetectable		 3rfmA-3a1iA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 6 ASP A 143
LEU A 144
ALA A 370
THR A 112
 None
 1.10A 3rozA-3a1iA:
undetectable		 3rozA-3a1iA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 7 GLY A 137
MET A 106
ILE A  80
VAL A 135
 None
 1.04A 4e1vB-3a1iA:
undetectable		 4e1vB-3a1iA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 6 GLY A 137
MET A 106
ILE A  80
VAL A 135
 None
 1.04A 4e1vF-3a1iA:
undetectable		 4e1vF-3a1iA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 8 GLY A 137
MET A 106
ILE A  80
VAL A 135
 None
 1.01A 4e1vH-3a1iA:
undetectable		 4e1vH-3a1iA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_B_MOAB502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 8 SER A 149
SER A 150
GLY A 156
GLY A 174
 None
 0.78A 4fo4B-3a1iA:
undetectable		 4fo4B-3a1iA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_A_ACTA603_0
(CHOLINE OXIDASE)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		3 / 3 ARG A 365
HIS A 369
SER A 364
 None
 0.94A 4mjwA-3a1iA:
undetectable
4mjwB-3a1iA:
undetectable		 4mjwA-3a1iA:
25.48
4mjwB-3a1iA:
25.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_B_ACTB603_0
(CHOLINE OXIDASE)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		3 / 3 SER A 364
ARG A 365
HIS A 369
 None
 0.91A 4mjwA-3a1iA:
undetectable
4mjwB-3a1iA:
undetectable		 4mjwA-3a1iA:
25.48
4mjwB-3a1iA:
25.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_A_STRA601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 6 ALA A 413
ILE A 480
GLY A 482
ILE A 318
 None
 0.62A 4r21A-3a1iA:
undetectable		 4r21A-3a1iA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVD_A_SAMA502_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		5 / 12 ILE A 279
GLY A 280
ALA A 413
VAL A 421
ILE A 480
 None
 0.83A 4rvdA-3a1iA:
undetectable		 4rvdA-3a1iA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_SAMA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		5 / 12 ILE A 279
GLY A 280
ALA A 413
VAL A 421
ILE A 480
 None
 0.83A 4rvgA-3a1iA:
undetectable		 4rvgA-3a1iA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2G_B_CTCB222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		5 / 12 SER A 147
ARG A 366
THR A 376
VAL A 377
ILE A 223
 None
 1.32A 4v2gB-3a1iA:
undetectable		 4v2gB-3a1iA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WAN_C_ACTC303_0
(BRANCHPOINT-BRIDGING
PROTEIN)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		3 / 3 ASP A 183
ARG A 164
PRO A  70
 None
 0.90A 4wanC-3a1iA:
undetectable		 4wanC-3a1iA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1008_1
(SERUM ALBUMIN)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		5 / 9 PHE A 442
ALA A 446
VAL A 380
SER A 374
VAL A 377
 None
 1.48A 4z69A-3a1iA:
2.3		 4z69A-3a1iA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 5 THR A 424
THR A 234
HIS A 238
LEU A 491
 None
 1.04A 5axaA-3a1iA:
undetectable		 5axaA-3a1iA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 5 THR A 424
THR A 234
HIS A 238
LEU A 491
 None
 1.05A 5axaC-3a1iA:
undetectable		 5axaC-3a1iA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_A_FUAA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 5 ILE A 247
LYS A  96
ILE A  95
VAL A  93
 None
 0.99A 5jmnA-3a1iA:
undetectable		 5jmnA-3a1iA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N1T_W_CUW201_0
(COPC)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		3 / 3 HIS A 484
ASP A 411
HIS A 461
 None
 0.96A 5n1tW-3a1iA:
undetectable		 5n1tW-3a1iA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_2
(PROTEASE)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		6 / 12 GLY A 174
ALA A 139
ASP A  97
ILE A  95
GLY A 190
ILE A 196
 None
 1.30A 5t8hB-3a1iA:
undetectable		 5t8hB-3a1iA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_2
(ADENOSYLHOMOCYSTEINA
SE)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 5 THR A 424
THR A 234
HIS A 238
LEU A 491
 None
 1.08A 5utuH-3a1iA:
undetectable		 5utuH-3a1iA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		5 / 12 GLY A 173
VAL A 215
VAL A 124
ASN A  98
ILE A 188
 None
 1.02A 5vopA-3a1iA:
undetectable		 5vopA-3a1iA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 6 GLU A 224
TYR A 396
GLY A 393
GLY A 392
 None
 0.85A 5x7pB-3a1iA:
undetectable		 5x7pB-3a1iA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		5 / 9 ALA A 187
ALA A 139
SER A 175
VAL A  99
GLY A 137
 None
 1.15A 6bklA-3a1iA:
undetectable
6bklB-3a1iA:
undetectable
6bklC-3a1iA:
undetectable
6bklD-3a1iA:
undetectable		 6bklA-3a1iA:
4.46
6bklB-3a1iA:
4.46
6bklC-3a1iA:
4.46
6bklD-3a1iA:
4.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		5 / 9 ALA A 429
SER A 430
ALA A 168
SER A 150
GLY A 170
 None
 1.22A 6bklA-3a1iA:
undetectable
6bklB-3a1iA:
undetectable
6bklC-3a1iA:
undetectable
6bklD-3a1iA:
undetectable		 6bklA-3a1iA:
4.46
6bklB-3a1iA:
4.46
6bklC-3a1iA:
4.46
6bklD-3a1iA:
4.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		5 / 9 ALA A 429
SER A 430
ALA A 168
SER A 150
GLY A 170
 None
 1.21A 6bklE-3a1iA:
undetectable
6bklF-3a1iA:
undetectable
6bklG-3a1iA:
undetectable
6bklH-3a1iA:
undetectable		 6bklE-3a1iA:
4.46
6bklF-3a1iA:
4.46
6bklG-3a1iA:
4.46
6bklH-3a1iA:
4.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 6 SER A 171
ALA A 139
ALA A 176
SER A 175
 UNU  A 522 ( 4.8A)
None
None
None
 0.89A 6bocA-3a1iA:
undetectable
6bocB-3a1iA:
undetectable
6bocC-3a1iA:
undetectable
6bocD-3a1iA:
undetectable		 6bocA-3a1iA:
4.46
6bocB-3a1iA:
4.46
6bocC-3a1iA:
4.46
6bocD-3a1iA:
4.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CJK_C_ACTC301_0
(IMMUNOGLOBULIN FAB
LIGHT CHAIN)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		4 / 4 VAL A 419
GLY A 482
ASP A 486
ASP A 487
 None
 1.20A 6cjkC-3a1iA:
undetectable		 6cjkC-3a1iA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_1
(HIV-1 PROTEASE)		 3a1i AMIDASE
(Rhodococcus
sp.
N-771) 		6 / 12 GLY A 174
ALA A 139
VAL A  93
ILE A  95
GLY A 189
ILE A 196
 None
 1.36A 6dj1B-3a1iA:
undetectable		 6dj1B-3a1iA:
10.78