SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a1z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHI_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3a1z HEMOLYMPH JUVENILE
HORMONE BINDING
PROTEIN
(Bombyx
mori) 		5 / 11 ILE A  60
ALA A  52
LEU A 185
LEU A 169
ILE A 103
 MPD  A 232 ( 4.4A)
None
None
None
None
 1.08A 1dhiB-3a1zA:
undetectable		 1dhiB-3a1zA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_C_ACTC3004_0
(BETA-CARBONIC
ANHYDRASE)		 3a1z HEMOLYMPH JUVENILE
HORMONE BINDING
PROTEIN
(Bombyx
mori) 		4 / 6 GLN A  73
TYR A 201
VAL A 126
GLY A 124
 None
 1.26A 1ekjC-3a1zA:
undetectable
1ekjD-3a1zA:
undetectable		 1ekjC-3a1zA:
23.62
1ekjD-3a1zA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 3a1z HEMOLYMPH JUVENILE
HORMONE BINDING
PROTEIN
(Bombyx
mori) 		5 / 12 VAL A  45
ILE A  97
TYR A 201
ILE A 154
LEU A  48
 None
 1.23A 1fm4A-3a1zA:
undetectable		 1fm4A-3a1zA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 3a1z HEMOLYMPH JUVENILE
HORMONE BINDING
PROTEIN
(Bombyx
mori) 		4 / 7 GLU A  26
LEU A  25
VAL A 204
LEU A  43
 None
 0.64A 1hk3A-3a1zA:
undetectable		 1hk3A-3a1zA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 3a1z HEMOLYMPH JUVENILE
HORMONE BINDING
PROTEIN
(Bombyx
mori) 		3 / 3 ARG A 209
ILE A  37
TRP A  38
 None
None
ZN  A 226 (-4.4A)
 1.14A 1nodB-3a1zA:
undetectable		 1nodB-3a1zA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 3a1z HEMOLYMPH JUVENILE
HORMONE BINDING
PROTEIN
(Bombyx
mori) 		3 / 3 ARG A 209
ILE A  37
TRP A  38
 None
None
ZN  A 226 (-4.4A)
 1.09A 2nodB-3a1zA:
undetectable		 2nodB-3a1zA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3a1z HEMOLYMPH JUVENILE
HORMONE BINDING
PROTEIN
(Bombyx
mori) 		5 / 12 VAL A  45
ILE A  97
TYR A 201
ILE A 154
LEU A  48
 None
 1.22A 4a84A-3a1zA:
undetectable		 4a84A-3a1zA:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 3a1z HEMOLYMPH JUVENILE
HORMONE BINDING
PROTEIN
(Bombyx
mori) 		4 / 4 ASN A  66
SER A 162
LEU A 115
THR A  68
 None
 0.96A 4an2A-3a1zA:
undetectable		 4an2A-3a1zA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P66_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3a1z HEMOLYMPH JUVENILE
HORMONE BINDING
PROTEIN
(Bombyx
mori) 		5 / 11 ILE A  60
ALA A  52
LEU A 185
LEU A 169
ILE A 103
 MPD  A 232 ( 4.4A)
None
None
None
None
 1.08A 4p66A-3a1zA:
undetectable		 4p66A-3a1zA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3a1z HEMOLYMPH JUVENILE
HORMONE BINDING
PROTEIN
(Bombyx
mori) 		5 / 12 VAL A 122
LEU A  48
ILE A 196
ILE A  97
ILE A  67
 None
 1.06A 4y0rA-3a1zA:
undetectable		 4y0rA-3a1zA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3a1z HEMOLYMPH JUVENILE
HORMONE BINDING
PROTEIN
(Bombyx
mori) 		4 / 6 ILE A 196
LEU A  48
PHE A  62
ARG A 189
 None
 1.06A 5b1aN-3a1zA:
undetectable
5b1aW-3a1zA:
undetectable		 5b1aN-3a1zA:
17.58
5b1aW-3a1zA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3a1z HEMOLYMPH JUVENILE
HORMONE BINDING
PROTEIN
(Bombyx
mori) 		4 / 6 PHE A  78
VAL A  87
TYR A 128
ILE A 208
 None
 1.18A 5iwuA-3a1zA:
undetectable		 5iwuA-3a1zA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3a1z HEMOLYMPH JUVENILE
HORMONE BINDING
PROTEIN
(Bombyx
mori) 		5 / 11 ILE A  67
PHE A  62
THR A 120
ILE A 193
ALA A 192
 None
None
None
None
MPD  A 232 ( 4.3A)
 1.04A 5lg3A-3a1zA:
undetectable		 5lg3A-3a1zA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3a1z HEMOLYMPH JUVENILE
HORMONE BINDING
PROTEIN
(Bombyx
mori) 		5 / 12 ILE A  67
PHE A  62
THR A 120
ILE A 193
ALA A 192
 None
None
None
None
MPD  A 232 ( 4.3A)
 1.03A 5lg3E-3a1zA:
undetectable		 5lg3E-3a1zA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MQT_C_STIC302_1
(DEOXYCYTIDINE KINASE)		 3a1z HEMOLYMPH JUVENILE
HORMONE BINDING
PROTEIN
(Bombyx
mori) 		5 / 12 ILE A 202
VAL A 126
GLN A  73
LEU A  70
GLU A 198
 None
 1.38A 5mqtC-3a1zA:
undetectable		 5mqtC-3a1zA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND2_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3a1z HEMOLYMPH JUVENILE
HORMONE BINDING
PROTEIN
(Bombyx
mori) 		5 / 12 VAL A  50
ASP A  49
LEU A 161
ALA A 192
LEU A  65
 None
None
None
MPD  A 232 ( 4.3A)
None
 1.04A 5nd2B-3a1zA:
undetectable		 5nd2B-3a1zA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3a1z HEMOLYMPH JUVENILE
HORMONE BINDING
PROTEIN
(Bombyx
mori) 		3 / 3 LYS A  90
LEU A  88
ARG A 127
 None
 0.93A 5yw0A-3a1zA:
undetectable		 5yw0A-3a1zA:
21.17