SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a2b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_GLYA1292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3a2b SERINE
PALMITOYLTRANSFERASE
(Sphingobacterium
multivorum) 		5 / 8 HIS A 138
SER A 185
HIS A 213
LYS A 244
ARG A 367
 PLP  A 400 ( 3.2A)
PLP  A 400 ( 4.2A)
PLP  A 400 (-4.1A)
PLP  A 400 ( 3.3A)
None
 1.14A 1eqbA-3a2bA:
28.6
1eqbB-3a2bA:
28.6		 1eqbA-3a2bA:
25.11
1eqbB-3a2bA:
25.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_GLYB2292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3a2b SERINE
PALMITOYLTRANSFERASE
(Sphingobacterium
multivorum) 		5 / 8 HIS A 138
SER A 185
HIS A 213
LYS A 244
ARG A 367
 PLP  A 400 ( 3.2A)
PLP  A 400 ( 4.2A)
PLP  A 400 (-4.1A)
PLP  A 400 ( 3.3A)
None
 1.14A 1eqbA-3a2bA:
28.6
1eqbB-3a2bA:
28.6		 1eqbA-3a2bA:
25.11
1eqbB-3a2bA:
25.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_GLYC3292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3a2b SERINE
PALMITOYLTRANSFERASE
(Sphingobacterium
multivorum) 		5 / 8 HIS A 138
SER A 185
HIS A 213
LYS A 244
ARG A 367
 PLP  A 400 ( 3.2A)
PLP  A 400 ( 4.2A)
PLP  A 400 (-4.1A)
PLP  A 400 ( 3.3A)
None
 1.14A 1eqbC-3a2bA:
28.6
1eqbD-3a2bA:
28.2		 1eqbC-3a2bA:
25.11
1eqbD-3a2bA:
25.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_GLYD4292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3a2b SERINE
PALMITOYLTRANSFERASE
(Sphingobacterium
multivorum) 		5 / 8 HIS A 138
SER A 185
HIS A 213
LYS A 244
ARG A 367
 PLP  A 400 ( 3.2A)
PLP  A 400 ( 4.2A)
PLP  A 400 (-4.1A)
PLP  A 400 ( 3.3A)
None
 1.14A 1eqbC-3a2bA:
28.6
1eqbD-3a2bA:
28.2		 1eqbC-3a2bA:
25.11
1eqbD-3a2bA:
25.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 3a2b SERINE
PALMITOYLTRANSFERASE
(Sphingobacterium
multivorum) 		5 / 12 VAL A 351
ILE A 366
ILE A 329
PHE A 390
VAL A 349
 None
 1.00A 1qhsA-3a2bA:
undetectable		 1qhsA-3a2bA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 3a2b SERINE
PALMITOYLTRANSFERASE
(Sphingobacterium
multivorum) 		4 / 7 ASP A 181
ASP A 210
ASP A 137
HIS A 157
 PLP  A 400 (-3.8A)
PLP  A 400 (-2.6A)
None
None
 1.35A 1t03A-3a2bA:
3.0		 1t03A-3a2bA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_A_SAMA1500_0
(ASPARTOKINASE)		 3a2b SERINE
PALMITOYLTRANSFERASE
(Sphingobacterium
multivorum) 		4 / 8 ILE A 141
ASP A 143
SER A 269
LEU A 121
 None
 0.97A 2cdqA-3a2bA:
undetectable		 2cdqA-3a2bA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 3a2b SERINE
PALMITOYLTRANSFERASE
(Sphingobacterium
multivorum) 		4 / 7 THR A 225
TYR A 155
ASN A 158
PHE A 184
 None
 0.88A 2hzqA-3a2bA:
undetectable		 2hzqA-3a2bA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_GLYB502_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3a2b SERINE
PALMITOYLTRANSFERASE
(Sphingobacterium
multivorum) 		4 / 8 HIS A 138
SER A 185
HIS A 213
LYS A 244
 PLP  A 400 ( 3.2A)
PLP  A 400 ( 4.2A)
PLP  A 400 (-4.1A)
PLP  A 400 ( 3.3A)
 1.07A 2vmyA-3a2bA:
29.2
2vmyB-3a2bA:
28.6		 2vmyA-3a2bA:
25.74
2vmyB-3a2bA:
25.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGQ_A_PCFA1275_0
(WNT INHIBITORY
FACTOR 1)		 3a2b SERINE
PALMITOYLTRANSFERASE
(Sphingobacterium
multivorum) 		5 / 12 ILE A 383
ILE A 379
PRO A 328
ILE A 366
MET A 386
 None
 1.00A 2ygqA-3a2bA:
undetectable		 2ygqA-3a2bA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QT0_A_486A4_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3a2b SERINE
PALMITOYLTRANSFERASE
(Sphingobacterium
multivorum) 		5 / 12 SER A 227
ALA A 226
TYR A 101
LEU A 215
ILE A 183
 None
 1.47A 3qt0A-3a2bA:
undetectable		 3qt0A-3a2bA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3a2b SERINE
PALMITOYLTRANSFERASE
(Sphingobacterium
multivorum) 		5 / 12 SER A 214
VAL A 217
GLN A  35
THR A  58
SER A  51
 None
 1.43A 4c49D-3a2bA:
undetectable		 4c49D-3a2bA:
24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3a2b SERINE
PALMITOYLTRANSFERASE
(Sphingobacterium
multivorum) 		5 / 11 GLY A 182
VAL A 191
SER A 214
ASP A 211
VAL A 209
 None
 0.70A 4d9hA-3a2bA:
undetectable		 4d9hA-3a2bA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3a2b SERINE
PALMITOYLTRANSFERASE
(Sphingobacterium
multivorum) 		5 / 9 GLY A 182
VAL A 191
GLU A 323
ASP A 211
VAL A 209
 None
 1.08A 4da6A-3a2bA:
undetectable		 4da6A-3a2bA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3a2b SERINE
PALMITOYLTRANSFERASE
(Sphingobacterium
multivorum) 		5 / 9 GLY A 182
VAL A 191
SER A 214
ASP A 211
VAL A 209
 None
 0.67A 4da6A-3a2bA:
undetectable		 4da6A-3a2bA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3a2b SERINE
PALMITOYLTRANSFERASE
(Sphingobacterium
multivorum) 		5 / 11 GLY A 182
VAL A 191
SER A 214
ASP A 211
VAL A 209
 None
 0.67A 4danA-3a2bA:
undetectable		 4danA-3a2bA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3a2b SERINE
PALMITOYLTRANSFERASE
(Sphingobacterium
multivorum) 		5 / 12 GLY A 182
VAL A 191
GLU A 323
ASP A 211
VAL A 209
 None
 1.02A 4danA-3a2bA:
undetectable
4danB-3a2bA:
undetectable		 4danA-3a2bA:
22.53
4danB-3a2bA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3a2b SERINE
PALMITOYLTRANSFERASE
(Sphingobacterium
multivorum) 		5 / 12 GLY A 182
VAL A 191
SER A 214
ASP A 211
VAL A 209
 None
 0.61A 4danA-3a2bA:
undetectable
4danB-3a2bA:
undetectable		 4danA-3a2bA:
22.53
4danB-3a2bA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3a2b SERINE
PALMITOYLTRANSFERASE
(Sphingobacterium
multivorum) 		5 / 12 LEU A 215
ASP A 211
ASN A 232
GLY A 103
PHE A 252
 None
 1.16A 4pgfA-3a2bA:
undetectable		 4pgfA-3a2bA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA602_1
(SERUM ALBUMIN)		 3a2b SERINE
PALMITOYLTRANSFERASE
(Sphingobacterium
multivorum) 		5 / 12 LEU A  98
TYR A 101
GLY A 250
SER A 248
LEU A 246
 None
 1.49A 4zbrA-3a2bA:
undetectable		 4zbrA-3a2bA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3a2b SERINE
PALMITOYLTRANSFERASE
(Sphingobacterium
multivorum) 		3 / 3 VAL A 270
LEU A 177
MET A 125
 None
 0.88A 5ikrA-3a2bA:
undetectable		 5ikrA-3a2bA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 3a2b SERINE
PALMITOYLTRANSFERASE
(Sphingobacterium
multivorum) 		4 / 7 LEU A 263
THR A 241
ASP A 211
LEU A 124
 None
PLP  A 400 (-3.8A)
None
None
 1.02A 5jq7B-3a2bA:
undetectable		 5jq7B-3a2bA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA826_0
(GEPHYRIN)		 3a2b SERINE
PALMITOYLTRANSFERASE
(Sphingobacterium
multivorum) 		3 / 3 HIS A 213
ARG A 367
ILE A 326
 PLP  A 400 (-4.1A)
None
None
 0.81A 6fgdA-3a2bA:
2.4		 6fgdA-3a2bA:
20.94