SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a2q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		4 / 8 CYH A 182
VAL A 147
GLY A 153
GLY A 152
 None
 0.77A 1ekjE-3a2qA:
undetectable
1ekjF-3a2qA:
undetectable		 1ekjE-3a2qA:
19.08
1ekjF-3a2qA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 11 GLY A 124
LEU A  74
GLY A 149
HIS A 167
GLU A 212
 ACA  A 601 ( 3.9A)
None
None
None
None
 1.17A 1iolA-3a2qA:
undetectable		 1iolA-3a2qA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 12 ARG A 191
PHE A 238
VAL A 363
ALA A 210
ALA A 209
 None
None
None
ACA  A 601 ( 4.9A)
None
 1.20A 1n5xA-3a2qA:
undetectable		 1n5xA-3a2qA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 12 ARG A 191
PHE A 238
VAL A 363
ALA A 210
ALA A 209
 None
None
None
ACA  A 601 ( 4.9A)
None
 1.20A 1n5xB-3a2qA:
undetectable		 1n5xB-3a2qA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_F_FUAF704_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 11 SER A 230
LEU A 225
VAL A 165
PHE A 112
VAL A 228
 None
 1.38A 1q23F-3a2qA:
undetectable		 1q23F-3a2qA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 11 SER A 230
LEU A 225
VAL A 165
PHE A 112
VAL A 228
 None
 1.44A 1q23I-3a2qA:
undetectable		 1q23I-3a2qA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 10 SER A 218
LEU A 225
VAL A 228
PHE A 112
VAL A 165
 None
 1.47A 1q23K-3a2qA:
undetectable		 1q23K-3a2qA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 11 SER A 218
LEU A 225
VAL A 228
PHE A 112
VAL A 165
 None
 1.39A 1q23L-3a2qA:
undetectable		 1q23L-3a2qA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TBF_A_VIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 9 LEU A 386
LEU A 303
ALA A 456
LEU A 463
PHE A 428
 None
 1.27A 1tbfA-3a2qA:
undetectable		 1tbfA-3a2qA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TBF_A_VIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 9 LEU A 386
LEU A 303
LEU A 463
GLN A 433
PHE A 428
 None
 1.21A 1tbfA-3a2qA:
undetectable		 1tbfA-3a2qA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_1
(DIHYDROFOLATE
REDUCTASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 12 ILE A 177
ALA A 172
GLN A 420
PRO A 267
ASN A 266
 None
ACA  A 602 (-3.6A)
None
None
None
 1.33A 1u70A-3a2qA:
undetectable		 1u70A-3a2qA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 12 VAL A 454
ARG A 367
GLY A 208
ILE A 315
TYR A 312
 None
 1.48A 1xvaA-3a2qA:
undetectable		 1xvaA-3a2qA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		4 / 7 GLU A 323
ALA A 171
ASN A 169
ALA A 210
 None
ACA  A 602 ( 3.3A)
None
ACA  A 601 ( 4.9A)
 1.07A 2ejfA-3a2qA:
undetectable		 2ejfA-3a2qA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_1
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		3 / 3 SER A 416
THR A 343
GLN A 126
 None
 0.67A 2fk8A-3a2qA:
undetectable		 2fk8A-3a2qA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_J_TACJ5888_1
(ELONGATION FACTOR
EF-TU)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		4 / 6 THR A 393
SER A 180
PRO A 448
VAL A 184
 None
 1.15A 2hdnI-3a2qA:
undetectable
2hdnJ-3a2qA:
undetectable
2hdnL-3a2qA:
undetectable		 2hdnI-3a2qA:
6.47
2hdnJ-3a2qA:
21.96
2hdnL-3a2qA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_L_TACL6888_1
(ELONGATION FACTOR
EF-TU)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		4 / 6 VAL A 184
THR A 393
SER A 180
PRO A 448
 None
 1.23A 2hdnJ-3a2qA:
undetectable
2hdnK-3a2qA:
undetectable
2hdnL-3a2qA:
undetectable		 2hdnJ-3a2qA:
21.96
2hdnK-3a2qA:
6.47
2hdnL-3a2qA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 12 PHE A  64
ALA A  65
SER A  61
ALA A  14
GLY A  66
 None
 1.27A 2igtC-3a2qA:
undetectable		 2igtC-3a2qA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OK6_D_BEZD2002_0
(AROMATIC AMINE
DEHYDROGENASE, LARGE
SUBUNIT
AROMATIC AMINE
DEHYDROGENASE, SMALL
SUBUNIT)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 9 GLN A 126
GLY A 124
LEU A  74
ASP A 202
ASN A 125
 None
ACA  A 601 ( 3.9A)
None
ACA  A 601 ( 4.7A)
ACA  A 601 ( 3.7A)
 1.12A 2ok6B-3a2qA:
0.0
2ok6D-3a2qA:
0.0		 2ok6B-3a2qA:
22.24
2ok6D-3a2qA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OK6_H_BEZH2001_0
(AROMATIC AMINE
DEHYDROGENASE, LARGE
SUBUNIT
AROMATIC AMINE
DEHYDROGENASE, SMALL
SUBUNIT)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 10 GLN A 126
GLY A 124
LEU A  74
ASP A 202
ASN A 125
 None
ACA  A 601 ( 3.9A)
None
ACA  A 601 ( 4.7A)
ACA  A 601 ( 3.7A)
 1.12A 2ok6A-3a2qA:
undetectable
2ok6H-3a2qA:
undetectable		 2ok6A-3a2qA:
22.24
2ok6H-3a2qA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_3
(PROTEASE RETROPEPSIN)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		6 / 12 LEU A 384
ALA A 281
ILE A 440
GLY A 450
VAL A 454
ILE A 385
 None
 1.20A 2q64B-3a2qA:
undetectable		 2q64B-3a2qA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		4 / 7 ILE A 251
ILE A 453
LEU A 438
ILE A 436
 None
 0.81A 2q83A-3a2qA:
undetectable		 2q83A-3a2qA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		6 / 12 GLY A 283
ALA A 284
ILE A 453
GLY A 450
ILE A 449
ILE A 385
 None
 1.27A 2rkfB-3a2qA:
undetectable		 2rkfB-3a2qA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_1
(PROTEASE RETROPEPSIN)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		6 / 12 GLY A 283
ALA A 284
ILE A 453
GLY A 450
ILE A 449
ILE A 385
 None
 1.22A 2rkgA-3a2qA:
undetectable		 2rkgA-3a2qA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		4 / 6 PHE A 308
TYR A 369
LEU A 303
VAL A 268
 None
 1.12A 2zawA-3a2qA:
undetectable		 2zawA-3a2qA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		4 / 8 SER A 180
THR A 388
VAL A 389
ALA A 281
 None
 0.90A 3ax7A-3a2qA:
undetectable		 3ax7A-3a2qA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_A_SALA1341_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		4 / 8 SER A 180
THR A 388
VAL A 389
ALA A 281
 None
 0.87A 3ax9A-3a2qA:
undetectable		 3ax9A-3a2qA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_PNTB901_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 12 TYR A 457
ASP A 236
GLY A 231
SER A 230
ASN A 205
 None
 1.49A 3hiiB-3a2qA:
undetectable		 3hiiB-3a2qA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		4 / 4 PRO A 387
THR A 388
GLY A 148
THR A 128
 None
 0.92A 3ib1A-3a2qA:
1.7		 3ib1A-3a2qA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		4 / 4 GLY A 450
VAL A 389
GLY A 148
THR A 128
 None
 0.95A 3ib2A-3a2qA:
1.5		 3ib2A-3a2qA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_D_VIAD901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 11 ARG A 108
ALA A 216
PHE A 103
LEU A  71
PHE A 112
 None
 1.31A 3jwqA-3a2qA:
undetectable
3jwqD-3a2qA:
undetectable		 3jwqA-3a2qA:
21.08
3jwqD-3a2qA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_2
(HIV-1 PROTEASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		3 / 3 ARG A 138
VAL A 181
THR A 393
 None
 0.84A 3k4vA-3a2qA:
undetectable		 3k4vA-3a2qA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		4 / 6 VAL A 373
LEU A 419
ILE A 177
LEU A 303
 None
 0.96A 3kk6A-3a2qA:
undetectable		 3kk6A-3a2qA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_2
(PROTEASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		3 / 3 ARG A 138
VAL A 181
THR A 393
 None
 0.71A 3ndtA-3a2qA:
undetectable		 3ndtA-3a2qA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		6 / 9 GLY A 283
ALA A 284
ILE A 453
GLY A 450
ILE A 449
ILE A 385
 None
 1.34A 3nu4B-3a2qA:
undetectable		 3nu4B-3a2qA:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA310_1
(BETA-LACTAMASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		4 / 8 LEU A 263
ALA A 279
GLY A 269
PRO A 267
 None
None
GOL  A 603 (-3.4A)
None
 0.92A 3ny4A-3a2qA:
undetectable		 3ny4A-3a2qA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_2
(PROTEASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		3 / 3 ARG A 138
VAL A 181
THR A 393
 None
 0.77A 3pwrA-3a2qA:
undetectable		 3pwrA-3a2qA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		3 / 4 SER A 443
GLY A 144
GLU A  41
 None
 0.67A 3raeA-3a2qA:
1.0
3raeC-3a2qA:
undetectable		 3raeA-3a2qA:
21.96
3raeC-3a2qA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_2
(PROTEASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		3 / 3 ARG A 138
VAL A 181
THR A 393
 None
 0.84A 3tl9A-3a2qA:
undetectable		 3tl9A-3a2qA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 10 SER A 218
LEU A 225
VAL A 228
PHE A 112
VAL A 165
 None
 1.40A 3u9fE-3a2qA:
undetectable		 3u9fE-3a2qA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 12 SER A 218
LEU A 225
VAL A 228
PHE A 112
VAL A 165
 None
 1.41A 3u9fH-3a2qA:
undetectable
3u9fI-3a2qA:
undetectable		 3u9fH-3a2qA:
17.65
3u9fI-3a2qA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 10 SER A 218
LEU A 225
VAL A 228
PHE A 112
VAL A 165
 None
 1.41A 3u9fI-3a2qA:
undetectable		 3u9fI-3a2qA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 10 SER A 230
LEU A 225
VAL A 165
PHE A 112
VAL A 228
 None
 1.50A 3u9fI-3a2qA:
undetectable		 3u9fI-3a2qA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_J_CLMJ221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 12 SER A 218
LEU A 225
VAL A 228
PHE A 112
VAL A 165
 None
 1.39A 3u9fJ-3a2qA:
undetectable
3u9fK-3a2qA:
undetectable		 3u9fJ-3a2qA:
17.65
3u9fK-3a2qA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 10 SER A 218
LEU A 225
VAL A 228
PHE A 112
VAL A 165
 None
 1.39A 3u9fK-3a2qA:
undetectable		 3u9fK-3a2qA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_N_CLMN221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 11 SER A 218
LEU A 225
VAL A 228
PHE A 112
VAL A 165
 None
 1.44A 3u9fN-3a2qA:
undetectable
3u9fO-3a2qA:
undetectable		 3u9fN-3a2qA:
17.65
3u9fO-3a2qA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_P_CLMP221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 9 SER A 218
LEU A 225
VAL A 228
PHE A 112
VAL A 165
 None
 1.46A 3u9fP-3a2qA:
undetectable		 3u9fP-3a2qA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 10 SER A 218
LEU A 225
VAL A 228
PHE A 112
VAL A 165
 None
 1.44A 3u9fR-3a2qA:
undetectable		 3u9fR-3a2qA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 12 SER A 218
LEU A 225
VAL A 228
PHE A 112
VAL A 165
 None
 1.41A 3u9fP-3a2qA:
undetectable
3u9fS-3a2qA:
undetectable		 3u9fP-3a2qA:
17.65
3u9fS-3a2qA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		4 / 4 SER A 150
ASP A 202
ASP A 204
ALA A 171
 ACA  A 601 ( 2.7A)
ACA  A 601 ( 4.7A)
None
ACA  A 602 ( 3.3A)
 1.31A 3uj6A-3a2qA:
undetectable		 3uj6A-3a2qA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		4 / 7 MET A 400
LEU A 401
SER A 412
GLU A 132
 None
 1.05A 4aq7A-3a2qA:
undetectable		 4aq7A-3a2qA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		3 / 3 ARG A  54
ARG A  55
ILE A  32
 None
 0.91A 4b7qA-3a2qA:
undetectable		 4b7qA-3a2qA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOS_A_4KOA201_1
(UNCHARACTERIZED
PROTEIN)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 12 PRO A 427
ARG A 176
PHE A 308
ARG A 306
LEU A 309
 None
 1.37A 4kosA-3a2qA:
undetectable		 4kosA-3a2qA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 12 PRO A 427
ARG A 176
PHE A 308
ARG A 306
LEU A 309
 None
 1.43A 4kotA-3a2qA:
0.2		 4kotA-3a2qA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A206_1
(UNCHARACTERIZED
PROTEIN)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 10 PRO A 427
ARG A 176
PHE A 308
ARG A 306
LEU A 309
 None
 1.39A 4kouA-3a2qA:
0.0		 4kouA-3a2qA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOV_A_KOVA204_1
(UNCHARACTERIZED
PROTEIN)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 12 PRO A 427
ARG A 176
PHE A 308
ARG A 306
LEU A 309
 None
 1.39A 4kovA-3a2qA:
undetectable		 4kovA-3a2qA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOW_A_CFXA204_1
(UNCHARACTERIZED
PROTEIN)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 12 PRO A 427
ARG A 176
PHE A 308
ARG A 306
LEU A 309
 None
 1.36A 4kowA-3a2qA:
undetectable		 4kowA-3a2qA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_A_QI9A602_0
(CYTOCHROME P450 2D6)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 9 LEU A 419
SER A 313
VAL A 430
VAL A 426
LEU A 366
 None
 1.34A 4wnvA-3a2qA:
undetectable		 4wnvA-3a2qA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		4 / 6 LEU A 115
TYR A  69
PRO A  68
GLU A  56
 None
 1.20A 4z4gA-3a2qA:
undetectable		 4z4gA-3a2qA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_F_MFXF2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		4 / 6 SER A 230
ASP A 170
ARG A 176
GLY A 186
 None
 0.91A 5cdqA-3a2qA:
undetectable
5cdqC-3a2qA:
undetectable
5cdqD-3a2qA:
undetectable		 5cdqA-3a2qA:
23.19
5cdqC-3a2qA:
23.19
5cdqD-3a2qA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSH_B_ACTB401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		4 / 5 ARG A 191
ARG A 367
LEU A 366
VAL A 363
 None
 1.32A 5cshB-3a2qA:
undetectable		 5cshB-3a2qA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		4 / 7 GLY A 155
SER A 151
GLY A 149
ALA A 179
 None
 0.68A 5e26A-3a2qA:
undetectable
5e26B-3a2qA:
undetectable		 5e26A-3a2qA:
21.21
5e26B-3a2qA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		4 / 7 ALA A 179
GLY A 155
SER A 151
GLY A 149
 None
 0.67A 5e26A-3a2qA:
undetectable
5e26B-3a2qA:
undetectable		 5e26A-3a2qA:
21.21
5e26B-3a2qA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		4 / 7 GLY A 155
SER A 151
GLY A 149
ALA A 179
 None
 0.68A 5e26C-3a2qA:
undetectable
5e26D-3a2qA:
undetectable		 5e26C-3a2qA:
21.21
5e26D-3a2qA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_D_PAUD601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		4 / 8 ALA A 179
GLY A 155
SER A 151
GLY A 149
 None
 0.70A 5e26C-3a2qA:
undetectable
5e26D-3a2qA:
undetectable		 5e26C-3a2qA:
21.21
5e26D-3a2qA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		6 / 12 GLY A 283
ALA A 284
ILE A 453
GLY A 450
ILE A 449
ILE A 385
 None
 1.37A 5e5jB-3a2qA:
undetectable		 5e5jB-3a2qA:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		4 / 6 SER A  93
GLY A 328
ASN A 327
MET A  90
 None
 1.08A 5j4nA-3a2qA:
undetectable		 5j4nA-3a2qA:
25.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		4 / 5 GLU A 460
GLY A 192
SER A 230
GLY A 231
 None
 1.13A 5kprA-3a2qA:
undetectable		 5kprA-3a2qA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_0
(METHYLTRANSFERASE)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		5 / 12 ALA A 174
VAL A 175
GLY A 153
GLU A 130
ALA A 156
 ACA  A 602 ( 3.0A)
None
None
None
None
 1.15A 5n5dA-3a2qA:
undetectable		 5n5dA-3a2qA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OS7_B_ACTB401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		4 / 5 ARG A 191
ARG A 367
LEU A 366
VAL A 363
 None
 1.34A 5os7B-3a2qA:
undetectable		 5os7B-3a2qA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA819_0
(GEPHYRIN)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		3 / 3 ARG A 350
GLY A 409
GLU A 408
 None
 0.63A 6fgdA-3a2qA:
undetectable		 6fgdA-3a2qA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GMD_A_ACTA401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE
(Arthrobacter
sp.
KI72) 		4 / 5 ARG A 191
ARG A 367
LEU A 366
VAL A 363
 None
 1.34A 6gmdA-3a2qA:
undetectable		 6gmdA-3a2qA:
20.16